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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
127
+9 vs. Q1 2024
Shares held
279.0M
+106.2M (+61.4%) vs. Q1 2024
Total value
$471.0M
+$53.2M (+12.7%) vs. Q1 2024
New holders
26
49 more added
Sold out
17
21 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 127 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ2 2024: $471.0M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2024.

Institutions holding LXRX in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Artal Group S.A.175,099,384$294.2M7.55%+57,546,100+49.0%Added
FMR LLC38,687,123$65.0M0.00%+24,793,061+178.4%Added
BlackRock Inc.9,890,153$16.6M0.00%+2,196,876+28.6%Added
Braidwell LP8,294,950$13.9M0.44%+8,294,950New
Vanguard Group Inc7,675,125$12.9M0.00%+1,273,900+19.9%Added
OrbiMed Advisors LLC5,846,100$9.82M0.21%+2,304,100+65.1%Added
Point72 Asset Management, L.P.4,121,191$6.92M0.02%+3,536,805+605.2%Added
Geode Capital Management, LLC3,250,535$5.46M0.00%+861,398+36.1%Added
Citadel Advisors LLC2,409,456$4.05M0.00%+2,274,979+1,691.7%Added
NEA Management Company, LLC2,382,286$4.00M0.30%00.0%Unchanged
State Street Corp2,313,477$3.89M0.00%+325,967+16.4%Added
Nantahala Capital Management, LLC2,304,150$3.87M0.39%+2,304,150New
Ameriprise Financial Inc2,092,710$3.52M0.00%+674,760+47.6%Added
Schonfeld Strategic Advisors LLC571,492$3.24M0.03%−388,658−40.5%Reduced
Opaleye Management Inc.1,875,000$3.15M0.72%+1,875,000New
Pinnacle Associates Ltd1,715,831$2.88M0.05%−31,999−1.8%Reduced
Charles Schwab Investment Management Inc1,359,148$2.28M0.00%+478,025+54.3%Added
Marshall Wace, LLP1,190,448$2.00M0.00%+691,276+138.5%Added
Northern Trust Corp997,528$1.68M0.00%+130,972+15.1%Added
Wellington Management Group LLP738,628$1.24M0.00%+52,210+7.6%Added
Millennium Management LLC597,321$1.00M0.00%+63,137+11.8%Added
Hennion & Walsh Asset Management, Inc.542,899$912.1K0.05%+542,899New
Bank of New York Mellon Corp401,908$675.2K0.00%+109,902+37.6%Added
Goldman Sachs Group Inc373,431$627.4K0.00%+217,217+139.1%Added
Morgan Stanley354,036$594.8K0.00%+109,827+45.0%Added
Alliancebernstein L.P.273,041$458.7K0.00%+53,100+24.1%Added
BBR Partners, LLC270,000$453.6K0.04%+240,000+800.0%Added
Nuveen Asset Management, LLC216,266$363.3K0.00%−307,911−58.7%Reduced
Virtus ETF Advisers LLC179,972$302.4K0.15%−113,120−38.6%Reduced
UBS Group AG161,113$270.7K0.00%−5,848−3.5%Reduced
Rhumbline Advisers152,785$256.7K0.00%+17,940+13.3%Added
Jane Street Group, LLC129,856$218.2K0.00%−151,732−53.9%Reduced
Altium Capital Management LP121,986$204.9K0.08%+121,986New
Price T Rowe Associates Inc117,179$197.0K0.00%+11,864+11.3%Added
Susquehanna International Group, LLP114,126$191.7K0.00%+103,283+952.5%Added
Commonwealth Equity Services, LLC101,134$170.0K0.00%+5,950+6.3%Added
Compagnie Lombard Odier SCmA94,000$157.9K0.00%00.0%Unchanged
JPMorgan Chase & Co90,426$151.9K0.00%+290+0.3%Added
Bank of America Corp87,185$146.5K0.00%+1,313+1.5%Added
Simplex Trading, LLC84,637$142.0K0.00%+84,637New
Dimensional Fund Advisors LP76,086$127.8K0.00%+26,143+52.3%Added
Bank of Montreal70,001$125.3K0.00%+30,000+75.0%Added
Corebridge Financial, Inc.61,770$103.8K0.00%+61,770New
LPL Financial LLC61,085$102.6K0.00%−28,878−32.1%Reduced
Pathstone Holdings, LLC60,038$100.9K0.00%−2,687−4.3%Reduced
Invesco Ltd.59,743$100.4K0.00%+9,925+19.9%Added
KWB Wealth40,640$97.5K0.01%00.0%Unchanged
MetLife Investment Management55,182$92.7K0.00%+22,320+67.9%Added
Russell Investments Group, Ltd.53,080$89.2K0.00%+3,980+8.1%Added
Stifel Financial Corp51,451$86.4K0.00%−723−1.4%Reduced
Manufacturers Life Insurance Company, The49,957$83.9K0.00%+14,411+40.5%Added
Mirae Asset Global ETFs Holdings Ltd.47,183$79.3K0.00%+47,183New
Wells Fargo & Company45,601$76.6K0.00%+14,586+47.0%Added
Victory Capital Management Inc45,341$76.2K0.00%+13,972+44.5%Added
China Universal Asset Management Co., Ltd.42,469$71.3K0.01%−4,461−9.5%Reduced
Wedbush Securities Inc40,850$69.0K0.00%−800−1.9%Reduced
Voya Investment Management LLC39,646$66.6K0.00%+10,677+36.9%Added
Barclays PLC39,437$66.3K0.00%−25,182−39.0%Reduced
University of Texas/Texas Am Investment Managment Co35,714$60.0K0.01%−35,714−50.0%Reduced
ProShare Advisors LLC34,725$58.3K0.00%+979+2.9%Added
New York State Common Retirement Fund33,702$56.6K0.00%−31−0.1%Reduced
Citigroup Inc33,130$55.7K0.00%+15,582+88.8%Added
Deutsche Bank AG31,890$53.6K0.00%−6,847−17.7%Reduced
Prosperity Financial Group, Inc.31,500$52.9K0.03%00.0%Unchanged
Great Point Partners LLC30,000$50.4K0.01%+30,000New
Tiaa Trust, National Association27,057$45.5K0.00%00.0%Unchanged
Tudor Investment Corp Et Al23,531$39.5K0.00%+23,531New
Principal Financial Group Inc22,759$38.2K0.00%+12,225+116.1%Added
Cerity Partners LLC22,512$37.8K0.00%00.0%Unchanged
SG Americas Securities, LLC22,197$37.0K0.00%+2,928+15.2%Added
Principal Securities, Inc.20,000$33.6K0.00%00.0%Unchanged
CVI Holdings, LLC20,000$33.6K0.03%+20,000New
JustInvest LLC19,329$32.5K0.00%+3,844+24.8%Added
Two Sigma Investments, LP19,156$32.2K0.00%−170,275−89.9%Reduced
BNP Paribas Arbitrage, SA18,607$31.3K0.00%−40,771−68.7%Reduced
Verition Fund Management LLC18,158$30.5K0.00%+18,158New
Coyle Financial Counsel LLC12,500$30.0K0.01%00.0%Unchanged
Two Sigma Securities, LLC17,771$29.9K0.00%+17,771New
Tower Research Capital LLC (TRC)16,952$28.5K0.00%−1,085−6.0%Reduced
Kestra Advisory Services, LLC15,500$26.0K0.00%+1,000+6.9%Added
Cresset Asset Management, LLC15,120$25.4K0.00%+15,120New
Truist Financial Corp13,400$22.5K0.00%+400+3.1%Added
North Star Asset Management Inc12,550$21.1K0.00%00.0%Unchanged
Pinnacle Wealth Management Advisory Group, LLC12,445$20.9K0.00%00.0%Unchanged
Vermillion & White Wealth Management Group, LLC12,415$20.9K0.02%00.0%Unchanged
Chemistry Wealth Management LLC12,000$20.2K0.01%00.0%Unchanged
Legal & General Group Plc11,466$19.3K0.00%+3,254+39.6%Added
Mirae Asset Global Investments Co., Ltd.10,792$18.8K0.00%+10,792New
Berger Financial Group, Inc10,929$18.4K0.00%00.0%Unchanged
Raymond James & Associates10,912$18.3K0.00%+71+0.7%Added
Captrust Financial Advisors10,865$18.3K0.00%+54+0.5%Added
Royal Bank of Canada10,838$18.0K0.00%+8,670+399.9%Added
CIBC World Markets Inc.10,980$18.0K0.00%+10,980New
Estabrook Capital Management10,000$16.8K0.00%00.0%Unchanged
River Wealth Advisors LLC10,000$16.8K0.00%00.0%Unchanged
LifeSteps Financial, Inc.10,000$16.8K0.01%00.0%Unchanged
Ameritas Investment Partners, Inc.8,867$14.9K0.00%00.0%Unchanged
California State Teachers Retirement System8,319$14.0K0.00%−997−10.7%Reduced
Nordwand Advisors, LLC4,000$6.72K0.00%00.0%Unchanged
Amalgamated Bank2,409$4.00K0.00%00.0%Unchanged