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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
127
+9 vs. Q1 2024
Shares held
279.0M
+106.2M (+61.4%) vs. Q1 2024
Total value
$471.0M
+$53.2M (+12.7%) vs. Q1 2024
New holders
26
49 more added
Sold out
17
21 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 127 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ2 2024: $471.0M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2024.

Institutions holding LXRX in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Avion Wealth407$00.00%00.0%Unchanged
CWM, LLC67$00.00%+65+3,250.0%Added
Covestor Ltd66$00.00%00.0%Unchanged
Federated Hermes, Inc.1$20.00%+1New
Farther Finance Advisors, LLC2$30.00%00.0%Unchanged
CIBC Private Wealth Group, LLC10$160.00%00.0%Unchanged
Coppell Advisory Solutions LLC52$870.00%+52New
Rothschild Investment LLC75$1260.00%+75New
Larson Financial Group LLC100$1680.00%+100New
The PNC Financial Services Group, Inc.111$1860.00%00.0%Unchanged
Nisa Investment Advisors, LLC121$2030.00%+72+146.9%Added
Comerica Bank122$2050.00%00.0%Unchanged
Syntax Research, Inc.142$2390.00%00.0%Unchanged
Optiver Holding B.V.155$2600.00%+155New
Innealta Capital, LLC175$2940.00%+175New
SJS Investment Consulting Inc.400$6720.00%+400New
Northwestern Mutual Wealth Management Co500$8400.00%00.0%Unchanged
SRS Capital Advisors, Inc.639$1.07K0.00%+639New
Advisor Group Holdings, Inc.742$1.25K0.00%−693−48.3%Reduced
Smartleaf Asset Management LLC726$1.26K0.00%+726New
Global Retirement Partners, LLC1,000$1.68K0.00%00.0%Unchanged
Signaturefd, LLC1,174$1.97K0.00%00.0%Unchanged
Daiwa Securities Group Inc.1,369$2.00K0.00%+935+215.4%Added
Quadrant Capital Group LLC1,371$2.30K0.00%00.0%Unchanged
Quintet Private Bank (Europe) S.A.1,682$3.24K0.00%−67−3.8%Reduced
National Bank of Canada2,200$3.66K0.00%00.0%Unchanged
Manchester Capital Management LLC2,380$4.00K0.00%+2,380New
Amalgamated Bank2,409$4.00K0.00%00.0%Unchanged
Nordwand Advisors, LLC4,000$6.72K0.00%00.0%Unchanged
California State Teachers Retirement System8,319$14.0K0.00%−997−10.7%Reduced
Ameritas Investment Partners, Inc.8,867$14.9K0.00%00.0%Unchanged
Estabrook Capital Management10,000$16.8K0.00%00.0%Unchanged
River Wealth Advisors LLC10,000$16.8K0.00%00.0%Unchanged
LifeSteps Financial, Inc.10,000$16.8K0.01%00.0%Unchanged
Royal Bank of Canada10,838$18.0K0.00%+8,670+399.9%Added
CIBC World Markets Inc.10,980$18.0K0.00%+10,980New
Captrust Financial Advisors10,865$18.3K0.00%+54+0.5%Added
Raymond James & Associates10,912$18.3K0.00%+71+0.7%Added
Berger Financial Group, Inc10,929$18.4K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.10,792$18.8K0.00%+10,792New
Legal & General Group Plc11,466$19.3K0.00%+3,254+39.6%Added
Chemistry Wealth Management LLC12,000$20.2K0.01%00.0%Unchanged
Vermillion & White Wealth Management Group, LLC12,415$20.9K0.02%00.0%Unchanged
Pinnacle Wealth Management Advisory Group, LLC12,445$20.9K0.00%00.0%Unchanged
North Star Asset Management Inc12,550$21.1K0.00%00.0%Unchanged
Truist Financial Corp13,400$22.5K0.00%+400+3.1%Added
Cresset Asset Management, LLC15,120$25.4K0.00%+15,120New
Kestra Advisory Services, LLC15,500$26.0K0.00%+1,000+6.9%Added
Tower Research Capital LLC (TRC)16,952$28.5K0.00%−1,085−6.0%Reduced
Two Sigma Securities, LLC17,771$29.9K0.00%+17,771New
Coyle Financial Counsel LLC12,500$30.0K0.01%00.0%Unchanged
Verition Fund Management LLC18,158$30.5K0.00%+18,158New
BNP Paribas Arbitrage, SA18,607$31.3K0.00%−40,771−68.7%Reduced
Two Sigma Investments, LP19,156$32.2K0.00%−170,275−89.9%Reduced
JustInvest LLC19,329$32.5K0.00%+3,844+24.8%Added
Principal Securities, Inc.20,000$33.6K0.00%00.0%Unchanged
CVI Holdings, LLC20,000$33.6K0.03%+20,000New
SG Americas Securities, LLC22,197$37.0K0.00%+2,928+15.2%Added
Cerity Partners LLC22,512$37.8K0.00%00.0%Unchanged
Principal Financial Group Inc22,759$38.2K0.00%+12,225+116.1%Added
Tudor Investment Corp Et Al23,531$39.5K0.00%+23,531New
Tiaa Trust, National Association27,057$45.5K0.00%00.0%Unchanged
Great Point Partners LLC30,000$50.4K0.01%+30,000New
Prosperity Financial Group, Inc.31,500$52.9K0.03%00.0%Unchanged
Deutsche Bank AG31,890$53.6K0.00%−6,847−17.7%Reduced
Citigroup Inc33,130$55.7K0.00%+15,582+88.8%Added
New York State Common Retirement Fund33,702$56.6K0.00%−31−0.1%Reduced
ProShare Advisors LLC34,725$58.3K0.00%+979+2.9%Added
University of Texas/Texas Am Investment Managment Co35,714$60.0K0.01%−35,714−50.0%Reduced
Barclays PLC39,437$66.3K0.00%−25,182−39.0%Reduced
Voya Investment Management LLC39,646$66.6K0.00%+10,677+36.9%Added
Wedbush Securities Inc40,850$69.0K0.00%−800−1.9%Reduced
China Universal Asset Management Co., Ltd.42,469$71.3K0.01%−4,461−9.5%Reduced
Victory Capital Management Inc45,341$76.2K0.00%+13,972+44.5%Added
Wells Fargo & Company45,601$76.6K0.00%+14,586+47.0%Added
Mirae Asset Global ETFs Holdings Ltd.47,183$79.3K0.00%+47,183New
Manufacturers Life Insurance Company, The49,957$83.9K0.00%+14,411+40.5%Added
Stifel Financial Corp51,451$86.4K0.00%−723−1.4%Reduced
Russell Investments Group, Ltd.53,080$89.2K0.00%+3,980+8.1%Added
MetLife Investment Management55,182$92.7K0.00%+22,320+67.9%Added
KWB Wealth40,640$97.5K0.01%00.0%Unchanged
Invesco Ltd.59,743$100.4K0.00%+9,925+19.9%Added
Pathstone Holdings, LLC60,038$100.9K0.00%−2,687−4.3%Reduced
LPL Financial LLC61,085$102.6K0.00%−28,878−32.1%Reduced
Corebridge Financial, Inc.61,770$103.8K0.00%+61,770New
Bank of Montreal70,001$125.3K0.00%+30,000+75.0%Added
Dimensional Fund Advisors LP76,086$127.8K0.00%+26,143+52.3%Added
Simplex Trading, LLC84,637$142.0K0.00%+84,637New
Bank of America Corp87,185$146.5K0.00%+1,313+1.5%Added
JPMorgan Chase & Co90,426$151.9K0.00%+290+0.3%Added
Compagnie Lombard Odier SCmA94,000$157.9K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC101,134$170.0K0.00%+5,950+6.3%Added
Susquehanna International Group, LLP114,126$191.7K0.00%+103,283+952.5%Added
Price T Rowe Associates Inc117,179$197.0K0.00%+11,864+11.3%Added
Altium Capital Management LP121,986$204.9K0.08%+121,986New
Jane Street Group, LLC129,856$218.2K0.00%−151,732−53.9%Reduced
Rhumbline Advisers152,785$256.7K0.00%+17,940+13.3%Added
UBS Group AG161,113$270.7K0.00%−5,848−3.5%Reduced
Virtus ETF Advisers LLC179,972$302.4K0.15%−113,120−38.6%Reduced
Nuveen Asset Management, LLC216,266$363.3K0.00%−307,911−58.7%Reduced