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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q2 2021

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
107
+1 vs. Q1 2021
Shares held
117.7M
+789.3K (+0.7%) vs. Q1 2021
Total value
$540.2M
−$146.0M (−21.3%) vs. Q1 2021
New holders
23
41 more added
Sold out
22
26 more reduced

1 institution that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 107 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ2 2021: $540.2M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2021.

Institutions holding LXRX in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Artal Group S.A.71,178,364$326.7M7.43%00.0%Unchanged
BVF Inc8,394,000$38.5M1.44%00.0%Unchanged
FMR LLC7,436,513$34.1M0.00%−1,666,325−18.3%Reduced
BlackRock Inc.4,646,859$21.3M0.00%+742,712+19.0%Added
Vanguard Group Inc3,969,989$18.2M0.00%+11,142+0.3%Added
D. E. Shaw & Co., Inc.3,402,425$15.6M0.02%+395,813+13.2%Added
NEA Management Company, LLC2,382,286$10.9M0.14%00.0%Unchanged
Pinnacle Associates Ltd2,190,782$10.1M0.18%+23,610+1.1%Added
JPMorgan Chase & Co1,313,161$6.03M0.00%+919,275+233.4%Added
Geode Capital Management, LLC1,280,654$5.88M0.00%+202,496+18.8%Added
State Street Corp1,037,647$4.76M0.00%+287,262+38.3%Added
Nomura Holdings Inc918,767$4.25M0.04%00.0%Unchanged
Northern Trust Corp727,996$3.34M0.00%+131,765+22.1%Added
Nuveen Asset Management, LLC668,483$3.07M0.00%+222,456+49.9%Added
Dimensional Fund Advisors LP541,655$2.49M0.00%+541,655New
Charles Schwab Investment Management Inc469,704$2.16M0.00%+46,478+11.0%Added
Boothe Investment Group, Inc.467,919$2.04M1.07%+31,980+7.3%Added
Bridgeway Capital Management, LLC400,092$1.84M0.03%−74,500−15.7%Reduced
Two Sigma Advisers, LP359,316$1.65M0.00%+294,743+456.4%Added
Norges Bank344,600$1.58M0.00%+344,600New
AQR Capital Management LLC325,004$1.49M0.00%+85,817+35.9%Added
Wells Fargo & Company293,408$1.35M0.00%+244,808+503.7%Added
Two Sigma Investments, LP292,896$1.34M0.00%−177,442−37.7%Reduced
AXA S.A.285,500$1.31M0.00%−116,800−29.0%Reduced
Panagora Asset Management Inc273,734$1.26M0.01%+101,861+59.3%Added
Russell Investments Group, Ltd.242,187$1.11M0.00%00.0%Unchanged
Bank of New York Mellon Corp241,335$1.11M0.00%+39,919+19.8%Added
Eversept Partners, LP229,289$1.05M0.10%−181,304−44.2%Reduced
Principal Financial Group Inc199,282$915.0K0.00%+17,420+9.6%Added
Millennium Management LLC179,855$826.0K0.00%−3,832−2.1%Reduced
Deutsche Bank AG166,281$764.0K0.00%+78,283+89.0%Added
State of Wisconsin Investment Board153,700$705.0K0.00%+99,100+181.5%Added
Massachusetts Financial Services Co151,659$696.0K0.00%+1,296+0.9%Added
Winton Group Ltd148,302$681.0K0.04%−15,367−9.4%Reduced
Morgan Stanley134,761$619.0K0.00%−570,377−80.9%Reduced
Price T Rowe Associates Inc129,568$595.0K0.00%+26,637+25.9%Added
Swiss National Bank127,300$584.0K0.00%+127,300New
Natixis Advisors, L.P.94,745$435.0K0.00%−114−0.1%Reduced
California State Teachers Retirement System93,834$431.0K0.00%+18,824+25.1%Added
Parametric Portfolio Associates LLC85,846$394.0K0.00%−6,855−7.4%Reduced
SG Americas Securities, LLC83,953$385.0K0.00%+83,953New
Rhumbline Advisers81,792$375.0K0.00%+26,714+48.5%Added
Stifel Financial Corp81,589$374.0K0.00%+3,671+4.7%Added
Vontobel Holding Ltd.80,000$367.0K0.00%00.0%Unchanged
UBS Asset Management Americas Inc76,375$350.6K0.00%+76,375New
Salem Investment Counselors Inc73,000$335.0K0.02%00.0%Unchanged
Goldman Sachs Group Inc70,988$326.0K0.00%+5,929+9.1%Added
Simplex Trading, LLC70,413$323.0K0.01%+44,739+174.3%Added
Renaissance Technologies LLC59,775$274.0K0.00%−252,704−80.9%Reduced
New York State Common Retirement Fund58,522$269.0K0.00%+29,322+100.4%Added
Los Angeles Capital Management LLC58,249$267.0K0.00%+58,249New
Alliancebernstein L.P.56,111$258.0K0.00%+12,000+27.2%Added
Caption Management, LLC54,333$250.0K0.02%+54,333New
Virtus ETF Advisers LLC46,699$214.0K0.09%+46,699New
Manufacturers Life Insurance Company, The41,525$191.0K0.00%+10,151+32.4%Added
Susquehanna International Group, LLP39,576$182.0K0.00%+39,576New
American International Group, Inc.38,038$175.0K0.00%+9,054+31.2%Added
Group One Trading, L.P.36,583$168.0K0.00%+36,583New
University of Texas/Texas Am Investment Managment Co35,714$164.0K0.13%00.0%Unchanged
Bank of America Corp33,246$153.0K0.00%−149,841−81.8%Reduced
Parallax Volatility Advisers, L.P.33,333$153.0K0.00%+33,333New
ExodusPoint Capital Management, LP31,838$146.0K0.00%−53,777−62.8%Reduced
Occudo Quantitative Strategies LP31,408$144.0K0.02%−34,891−52.6%Reduced
Credit Suisse AG31,562$144.0K0.00%+20,526+186.0%Added
State Board of Administration of Florida Retirement System29,214$134.0K0.00%+382+1.3%Added
Voya Investment Management LLC26,907$124.0K0.00%+6,507+31.9%Added
Invesco Ltd.23,185$106.0K0.00%+10,714+85.9%Added
Federated Hermes, Inc.21,505$99.0K0.00%+2,083+10.7%Added
PDT Partners, LLC21,454$98.0K0.01%−5,106−19.2%Reduced
Summit Global Investments20,700$95.0K0.01%+20,700New
ProShare Advisors LLC17,612$81.0K0.00%+4,323+32.5%Added
HighVista Strategies LLC16,043$74.0K0.05%+16,043New
Susquehanna Fundamental Investments, LLC15,800$73.0K0.00%+15,800New
STRS Ohio15,700$72.0K0.00%−103,100−86.8%Reduced
Arizona State Retirement System15,696$72.0K0.00%+15,696New
Jane Street Group, LLC15,211$70.0K0.00%−7,465−32.9%Reduced
Tudor Investment Corp Et Al15,061$69.0K0.00%+15,061New
Wolverine Trading, LLC13,677$68.0K0.00%+13,677New
Commonwealth Equity Services, LLC14,169$65.0K0.00%00.0%Unchanged
Barclays PLC13,250$60.0K0.00%−28,378−68.2%Reduced
Squarepoint Ops LLC12,752$59.0K0.00%−74,745−85.4%Reduced
Citadel Advisors LLC11,633$54.0K0.00%−120,859−91.2%Reduced
Citigroup Inc11,595$53.0K0.00%+8,124+234.1%Added
Amalgamated Bank10,868$50.0K0.00%+10,868New
Klingenstein Fields & Co LP10,618$49.0K0.00%00.0%Unchanged
Victory Capital Management Inc10,693$49.0K0.00%+578+5.7%Added
Pegasus Asset Management, Inc.10,000$46.0K0.02%00.0%Unchanged
O'Shaughnessy Asset Management, LLC6,547$30.0K0.00%−25,475−79.6%Reduced
Legal & General Group Plc6,154$28.0K0.00%+696+12.8%Added
Ameritas Investment Partners, Inc.5,367$25.0K0.00%+1,585+41.9%Added
Royal Bank of Canada5,185$23.0K0.00%+533+11.5%Added
Tower Research Capital LLC (TRC)3,857$18.0K0.00%−2,267−37.0%Reduced
Compagnie Lombard Odier SCmA4,000$18.0K0.00%00.0%Unchanged
Quantbot Technologies LP3,625$16.0K0.00%−24,317−87.0%Reduced
Tarbox Family Office, Inc.3,000$14.0K0.00%+3,000New
Hall Laurie J Trustee2,880$13.0K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA2,757$12.7K0.00%−4,041−59.4%Reduced
UBS Group AG1,991$9.00K0.00%−11,657−85.4%Reduced
Meeder Asset Management Inc1,535$7.00K0.00%+1,535New
Advisor Group Holdings, Inc.1,324$6.00K0.00%−365−21.6%Reduced