Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 110
- +14 vs. Q3 2021
- Shares held
- 121.6M
- +355.0K (+0.3%) vs. Q3 2021
- Total value
- $478.9M
- −$104.1M (−17.9%) vs. Q3 2021
- New holders
- 24
- 38 more added
- Sold out
- 10
- 29 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Artal Group S.A. | 71,178,364 | $280.4M | 8.24% | 00.0% | Unchanged |
| BVF Inc | 14,360,000 | $56.6M | 2.05% | 00.0% | Unchanged |
| FMR LLC | 5,668,138 | $22.3M | 0.00% | −793,218−12.3% | Reduced |
| BlackRock Inc. | 4,547,924 | $17.9M | 0.00% | −102,746−2.2% | Reduced |
| Vanguard Group Inc | 4,151,752 | $16.4M | 0.00% | +166,572+4.2% | Added |
| D. E. Shaw & Co., Inc. | 2,808,428 | $11.1M | 0.01% | −407,620−12.7% | Reduced |
| NEA Management Company, LLC | 2,382,286 | $9.39M | 0.19% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 2,127,662 | $8.38M | 0.14% | +30,015+1.4% | Added |
| State Street Corp | 1,215,018 | $4.79M | 0.00% | +113,265+10.3% | Added |
| Geode Capital Management, LLC | 1,197,739 | $4.72M | 0.00% | +3,817+0.3% | Added |
| JPMorgan Chase & Co | 1,148,090 | $4.52M | 0.00% | −9,613−0.8% | Reduced |
| Eversept Partners, LP | 797,694 | $3.14M | 0.26% | −75,000−8.6% | Reduced |
| Dimensional Fund Advisors LP | 772,978 | $3.05M | 0.00% | +277,540+56.0% | Added |
| Northern Trust Corp | 688,376 | $2.71M | 0.00% | +2980.0% | Added |
| Nomura Holdings Inc | 578,380 | $2.28M | 0.01% | −87,366−13.1% | Reduced |
| Allspring Global Investments Holdings, LLC | 573,499 | $2.26M | 0.00% | +573,499 | New |
| Wells Fargo & Company | 492,731 | $1.94M | 0.00% | −60,232−10.9% | Reduced |
| Charles Schwab Investment Management Inc | 488,418 | $1.93M | 0.00% | +12,624+2.7% | Added |
| Panagora Asset Management Inc | 289,479 | $1.14M | 0.01% | +325+0.1% | Added |
| Bank of New York Mellon Corp | 284,248 | $1.12M | 0.00% | +23,258+8.9% | Added |
| Bank of America Corp | 276,523 | $1.09M | 0.00% | +257,515+1,354.8% | Added |
| Millennium Management LLC | 255,138 | $1.00M | 0.00% | +177,101+226.9% | Added |
| Russell Investments Group, Ltd. | 250,317 | $985.0K | 0.00% | +8,130+3.4% | Added |
| Prudential Financial Inc | 249,708 | $984.0K | 0.00% | +249,708 | New |
| Nuveen Asset Management, LLC | 242,353 | $904.0K | 0.00% | −340,947−58.5% | Reduced |
| Wellington Management Group LLP | 215,541 | $849.0K | 0.00% | +215,541 | New |
| Integral Health Asset Management, LLC | 200,000 | $788.0K | 0.22% | −150,000−42.9% | Reduced |
| Fisher Asset Management, LLC | 170,770 | $673.0K | 0.00% | +170,770 | New |
| State of Wisconsin Investment Board | 157,500 | $621.0K | 0.00% | −1,700−1.1% | Reduced |
| Goldman Sachs Group Inc | 157,482 | $621.0K | 0.00% | +67,569+75.1% | Added |
| Tudor Investment Corp Et Al | 150,948 | $595.0K | 0.01% | +42,407+39.1% | Added |
| Price T Rowe Associates Inc | 143,632 | $566.0K | 0.00% | +14,064+10.9% | Added |
| Susquehanna International Group, LLP | 135,776 | $535.0K | 0.00% | +4,427+3.4% | Added |
| Bridgeway Capital Management, LLC | 135,500 | $534.0K | 0.01% | −244,592−64.4% | Reduced |
| Group One Trading, L.P. | 134,678 | $531.0K | 0.01% | +118,305+722.6% | Added |
| Swiss National Bank | 127,300 | $502.0K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 119,274 | $470.0K | 0.00% | −84,085−41.3% | Reduced |
| Los Angeles Capital Management LLC | 118,867 | $468.0K | 0.00% | −332−0.3% | Reduced |
| Morgan Stanley | 108,468 | $427.0K | 0.00% | +8,893+8.9% | Added |
| Stifel Financial Corp | 105,419 | $415.0K | 0.00% | −10,495−9.1% | Reduced |
| BNP Paribas Arbitrage, SA | 103,344 | $407.2K | 0.00% | +88,103+578.1% | Added |
| HRT Financial LP | 101,561 | $400.0K | 0.00% | +101,561 | New |
| UBS Group AG | 96,000 | $378.0K | 0.00% | +92,026+2,315.7% | Added |
| Natixis Advisors, L.P. | 93,969 | $370.0K | 0.00% | −568−0.6% | Reduced |
| Rhumbline Advisers | 86,660 | $341.0K | 0.00% | +2,669+3.2% | Added |
| California State Teachers Retirement System | 85,888 | $338.0K | 0.00% | +2,000+2.4% | Added |
| Barclays PLC | 84,970 | $335.0K | 0.00% | +57,223+206.2% | Added |
| Parametric Portfolio Associates LLC | 84,335 | $332.0K | 0.00% | +5,537+7.0% | Added |
| UBS Asset Management Americas Inc | 83,874 | $330.5K | 0.00% | 00.0% | Unchanged |
| Susquehanna Fundamental Investments, LLC | 79,855 | $315.0K | 0.01% | −14,367−15.2% | Reduced |
| AXA S.A. | 75,200 | $296.0K | 0.00% | +75,200 | New |
| Salem Investment Counselors Inc | 73,000 | $288.0K | 0.01% | 00.0% | Unchanged |
| Cerity Partners LLC | 73,000 | $288.0K | 0.00% | +73,000 | New |
| Principal Financial Group Inc | 70,789 | $279.0K | 0.00% | −122,623−63.4% | Reduced |
| Cubist Systematic Strategies, LLC | 66,808 | $263.0K | 0.00% | +22,204+49.8% | Added |
| Alliancebernstein L.P. | 50,111 | $197.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 47,145 | $185.0K | 0.01% | −12,129−20.5% | Reduced |
| Credit Suisse AG | 42,744 | $168.0K | 0.00% | −2,264−5.0% | Reduced |
| Deutsche Bank AG | 42,411 | $167.0K | 0.00% | +2,158+5.4% | Added |
| Virtus ETF Advisers LLC | 41,584 | $164.0K | 0.06% | −2,794−6.3% | Reduced |
| Manufacturers Life Insurance Company, The | 39,340 | $155.0K | 0.00% | +270+0.7% | Added |
| Squarepoint Ops LLC | 38,765 | $153.0K | 0.00% | +26,451+214.8% | Added |
| Jane Street Group, LLC | 38,467 | $152.0K | 0.00% | −1,253−3.2% | Reduced |
| Jump Financial, LLC | 38,700 | $152.0K | 0.01% | +38,700 | New |
| American International Group, Inc. | 37,202 | $147.0K | 0.00% | +47+0.1% | Added |
| ProShare Advisors LLC | 36,257 | $143.0K | 0.00% | +36,257 | New |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $141.0K | 0.06% | 00.0% | Unchanged |
| Parallax Volatility Advisers, L.P. | 35,537 | $140.0K | 0.00% | +35,537 | New |
| ExodusPoint Capital Management, LP | 33,901 | $134.0K | 0.00% | +9,700+40.1% | Added |
| New York State Common Retirement Fund | 33,447 | $132.0K | 0.00% | −149−0.4% | Reduced |
| Citadel Advisors LLC | 33,046 | $130.0K | 0.00% | −13,810−29.5% | Reduced |
| Gsa Capital Partners LLP | 31,562 | $124.0K | 0.02% | +31,562 | New |
| State Board of Administration of Florida Retirement System | 29,390 | $116.0K | 0.00% | +176+0.6% | Added |
| Voya Investment Management LLC | 29,176 | $115.0K | 0.00% | +2,269+8.4% | Added |
| Invesco Ltd. | 28,778 | $113.0K | 0.00% | +1,025+3.7% | Added |
| Victory Capital Management Inc | 27,951 | $110.0K | 0.00% | +6,986+33.3% | Added |
| MetLife Investment Management | 25,604 | $100.9K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 23,607 | $93.0K | 0.00% | +14,672+164.2% | Added |
| Metropolitan Life Insurance Co | 20,131 | $79.3K | 0.00% | +760+3.9% | Added |
| SG Americas Securities, LLC | 19,844 | $78.0K | 0.00% | −40,148−66.9% | Reduced |
| Legal & General Group Plc | 17,566 | $69.0K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 15,554 | $61.0K | 0.00% | −178−1.1% | Reduced |
| Commonwealth Equity Services, LLC | 14,276 | $56.0K | 0.00% | 00.0% | Unchanged |
| Schechter Investment Advisors, LLC | 14,217 | $56.0K | 0.01% | +14,217 | New |
| Royal Bank of Canada | 13,786 | $54.0K | 0.00% | +7,109+106.5% | Added |
| Aigen Investment Management, LP | 13,429 | $53.0K | 0.00% | +13,429 | New |
| Adviser Investments LLC | 13,289 | $52.0K | 0.00% | +13,289 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,688 | $50.0K | 0.00% | +12,688 | New |
| Campbell & CO Investment Adviser LLC | 11,900 | $47.0K | 0.02% | −19,500−62.1% | Reduced |
| Janus Henderson Group PLC | 11,786 | $46.0K | 0.00% | +11,786 | New |
| Equitable Holdings, Inc. | 11,340 | $45.0K | 0.00% | +11,340 | New |
| Teacher Retirement System of Texas | 10,901 | $43.0K | 0.00% | +10,901 | New |
| Winton Group Ltd | 10,688 | $42.0K | 0.00% | −101,432−90.5% | Reduced |
| Amalgamated Bank | 10,304 | $41.0K | 0.00% | −149−1.4% | Reduced |
| Estabrook Capital Management | 10,000 | $39.4K | 0.01% | +10,000 | New |
| Pegasus Asset Management, Inc. | 10,000 | $39.0K | 0.02% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,681 | $30.0K | 0.00% | −7,319−48.8% | Reduced |
| Ameritas Investment Partners, Inc. | 5,367 | $21.0K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 4,635 | $18.0K | 0.00% | +4,635 | New |
| Compagnie Lombard Odier SCmA | 4,000 | $16.0K | 0.00% | 00.0% | Unchanged |