Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 110
- +14 vs. Q3 2021
- Shares held
- 121.6M
- +355.0K (+0.3%) vs. Q3 2021
- Total value
- $478.9M
- −$104.1M (−17.9%) vs. Q3 2021
- New holders
- 24
- 38 more added
- Sold out
- 10
- 29 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Captrust Financial Advisors | 1 | $0 | 0.00% | +1 | New |
| Northwestern Mutual Wealth Management Co | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| Avion Wealth | 407 | $2.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 434 | $2.00K | 0.00% | +434 | New |
| Costello Asset Management, INC | 500 | $2.00K | 0.00% | +500 | New |
| Farmers & Merchants Investments Inc | 1,000 | $4.00K | 0.00% | 00.0% | Unchanged |
| TCI Wealth Advisors, Inc. | 991 | $4.00K | 0.00% | +991 | New |
| Hall Laurie J Trustee | 1,650 | $7.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 2,559 | $10.0K | 0.00% | +1,035+67.9% | Added |
| Quantbot Technologies LP | 3,625 | $14.0K | 0.00% | 00.0% | Unchanged |
| Compagnie Lombard Odier SCmA | 4,000 | $16.0K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 4,635 | $18.0K | 0.00% | +4,635 | New |
| Ameritas Investment Partners, Inc. | 5,367 | $21.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,681 | $30.0K | 0.00% | −7,319−48.8% | Reduced |
| Pegasus Asset Management, Inc. | 10,000 | $39.0K | 0.02% | 00.0% | Unchanged |
| Estabrook Capital Management | 10,000 | $39.4K | 0.01% | +10,000 | New |
| Amalgamated Bank | 10,304 | $41.0K | 0.00% | −149−1.4% | Reduced |
| Winton Group Ltd | 10,688 | $42.0K | 0.00% | −101,432−90.5% | Reduced |
| Teacher Retirement System of Texas | 10,901 | $43.0K | 0.00% | +10,901 | New |
| Equitable Holdings, Inc. | 11,340 | $45.0K | 0.00% | +11,340 | New |
| Janus Henderson Group PLC | 11,786 | $46.0K | 0.00% | +11,786 | New |
| Campbell & CO Investment Adviser LLC | 11,900 | $47.0K | 0.02% | −19,500−62.1% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,688 | $50.0K | 0.00% | +12,688 | New |
| Adviser Investments LLC | 13,289 | $52.0K | 0.00% | +13,289 | New |
| Aigen Investment Management, LP | 13,429 | $53.0K | 0.00% | +13,429 | New |
| Royal Bank of Canada | 13,786 | $54.0K | 0.00% | +7,109+106.5% | Added |
| Commonwealth Equity Services, LLC | 14,276 | $56.0K | 0.00% | 00.0% | Unchanged |
| Schechter Investment Advisors, LLC | 14,217 | $56.0K | 0.01% | +14,217 | New |
| Arizona State Retirement System | 15,554 | $61.0K | 0.00% | −178−1.1% | Reduced |
| Legal & General Group Plc | 17,566 | $69.0K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 19,844 | $78.0K | 0.00% | −40,148−66.9% | Reduced |
| Metropolitan Life Insurance Co | 20,131 | $79.3K | 0.00% | +760+3.9% | Added |
| Citigroup Inc | 23,607 | $93.0K | 0.00% | +14,672+164.2% | Added |
| MetLife Investment Management | 25,604 | $100.9K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 27,951 | $110.0K | 0.00% | +6,986+33.3% | Added |
| Invesco Ltd. | 28,778 | $113.0K | 0.00% | +1,025+3.7% | Added |
| Voya Investment Management LLC | 29,176 | $115.0K | 0.00% | +2,269+8.4% | Added |
| State Board of Administration of Florida Retirement System | 29,390 | $116.0K | 0.00% | +176+0.6% | Added |
| Gsa Capital Partners LLP | 31,562 | $124.0K | 0.02% | +31,562 | New |
| Citadel Advisors LLC | 33,046 | $130.0K | 0.00% | −13,810−29.5% | Reduced |
| New York State Common Retirement Fund | 33,447 | $132.0K | 0.00% | −149−0.4% | Reduced |
| ExodusPoint Capital Management, LP | 33,901 | $134.0K | 0.00% | +9,700+40.1% | Added |
| Parallax Volatility Advisers, L.P. | 35,537 | $140.0K | 0.00% | +35,537 | New |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $141.0K | 0.06% | 00.0% | Unchanged |
| ProShare Advisors LLC | 36,257 | $143.0K | 0.00% | +36,257 | New |
| American International Group, Inc. | 37,202 | $147.0K | 0.00% | +47+0.1% | Added |
| Jane Street Group, LLC | 38,467 | $152.0K | 0.00% | −1,253−3.2% | Reduced |
| Jump Financial, LLC | 38,700 | $152.0K | 0.01% | +38,700 | New |
| Squarepoint Ops LLC | 38,765 | $153.0K | 0.00% | +26,451+214.8% | Added |
| Manufacturers Life Insurance Company, The | 39,340 | $155.0K | 0.00% | +270+0.7% | Added |
| Virtus ETF Advisers LLC | 41,584 | $164.0K | 0.06% | −2,794−6.3% | Reduced |
| Deutsche Bank AG | 42,411 | $167.0K | 0.00% | +2,158+5.4% | Added |
| Credit Suisse AG | 42,744 | $168.0K | 0.00% | −2,264−5.0% | Reduced |
| Simplex Trading, LLC | 47,145 | $185.0K | 0.01% | −12,129−20.5% | Reduced |
| Alliancebernstein L.P. | 50,111 | $197.0K | 0.00% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 66,808 | $263.0K | 0.00% | +22,204+49.8% | Added |
| Principal Financial Group Inc | 70,789 | $279.0K | 0.00% | −122,623−63.4% | Reduced |
| Salem Investment Counselors Inc | 73,000 | $288.0K | 0.01% | 00.0% | Unchanged |
| Cerity Partners LLC | 73,000 | $288.0K | 0.00% | +73,000 | New |
| AXA S.A. | 75,200 | $296.0K | 0.00% | +75,200 | New |
| Susquehanna Fundamental Investments, LLC | 79,855 | $315.0K | 0.01% | −14,367−15.2% | Reduced |
| UBS Asset Management Americas Inc | 83,874 | $330.5K | 0.00% | 00.0% | Unchanged |
| Parametric Portfolio Associates LLC | 84,335 | $332.0K | 0.00% | +5,537+7.0% | Added |
| Barclays PLC | 84,970 | $335.0K | 0.00% | +57,223+206.2% | Added |
| California State Teachers Retirement System | 85,888 | $338.0K | 0.00% | +2,000+2.4% | Added |
| Rhumbline Advisers | 86,660 | $341.0K | 0.00% | +2,669+3.2% | Added |
| Natixis Advisors, L.P. | 93,969 | $370.0K | 0.00% | −568−0.6% | Reduced |
| UBS Group AG | 96,000 | $378.0K | 0.00% | +92,026+2,315.7% | Added |
| HRT Financial LP | 101,561 | $400.0K | 0.00% | +101,561 | New |
| BNP Paribas Arbitrage, SA | 103,344 | $407.2K | 0.00% | +88,103+578.1% | Added |
| Stifel Financial Corp | 105,419 | $415.0K | 0.00% | −10,495−9.1% | Reduced |
| Morgan Stanley | 108,468 | $427.0K | 0.00% | +8,893+8.9% | Added |
| Los Angeles Capital Management LLC | 118,867 | $468.0K | 0.00% | −332−0.3% | Reduced |
| AQR Capital Management LLC | 119,274 | $470.0K | 0.00% | −84,085−41.3% | Reduced |
| Swiss National Bank | 127,300 | $502.0K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 134,678 | $531.0K | 0.01% | +118,305+722.6% | Added |
| Bridgeway Capital Management, LLC | 135,500 | $534.0K | 0.01% | −244,592−64.4% | Reduced |
| Susquehanna International Group, LLP | 135,776 | $535.0K | 0.00% | +4,427+3.4% | Added |
| Price T Rowe Associates Inc | 143,632 | $566.0K | 0.00% | +14,064+10.9% | Added |
| Tudor Investment Corp Et Al | 150,948 | $595.0K | 0.01% | +42,407+39.1% | Added |
| State of Wisconsin Investment Board | 157,500 | $621.0K | 0.00% | −1,700−1.1% | Reduced |
| Goldman Sachs Group Inc | 157,482 | $621.0K | 0.00% | +67,569+75.1% | Added |
| Fisher Asset Management, LLC | 170,770 | $673.0K | 0.00% | +170,770 | New |
| Integral Health Asset Management, LLC | 200,000 | $788.0K | 0.22% | −150,000−42.9% | Reduced |
| Wellington Management Group LLP | 215,541 | $849.0K | 0.00% | +215,541 | New |
| Nuveen Asset Management, LLC | 242,353 | $904.0K | 0.00% | −340,947−58.5% | Reduced |
| Prudential Financial Inc | 249,708 | $984.0K | 0.00% | +249,708 | New |
| Russell Investments Group, Ltd. | 250,317 | $985.0K | 0.00% | +8,130+3.4% | Added |
| Millennium Management LLC | 255,138 | $1.00M | 0.00% | +177,101+226.9% | Added |
| Bank of America Corp | 276,523 | $1.09M | 0.00% | +257,515+1,354.8% | Added |
| Bank of New York Mellon Corp | 284,248 | $1.12M | 0.00% | +23,258+8.9% | Added |
| Panagora Asset Management Inc | 289,479 | $1.14M | 0.01% | +325+0.1% | Added |
| Charles Schwab Investment Management Inc | 488,418 | $1.93M | 0.00% | +12,624+2.7% | Added |
| Wells Fargo & Company | 492,731 | $1.94M | 0.00% | −60,232−10.9% | Reduced |
| Allspring Global Investments Holdings, LLC | 573,499 | $2.26M | 0.00% | +573,499 | New |
| Nomura Holdings Inc | 578,380 | $2.28M | 0.01% | −87,366−13.1% | Reduced |
| Northern Trust Corp | 688,376 | $2.71M | 0.00% | +2980.0% | Added |
| Dimensional Fund Advisors LP | 772,978 | $3.05M | 0.00% | +277,540+56.0% | Added |
| Eversept Partners, LP | 797,694 | $3.14M | 0.26% | −75,000−8.6% | Reduced |
| JPMorgan Chase & Co | 1,148,090 | $4.52M | 0.00% | −9,613−0.8% | Reduced |