Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 105
- +7 vs. Q3 2022
- Shares held
- 146.9M
- −1.99M (−1.3%) vs. Q3 2022
- Total value
- $280.5M
- −$76.8M (−21.5%) vs. Q3 2022
- New holders
- 14
- 38 more added
- Sold out
- 7
- 31 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avion Wealth | 407 | $0 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 67 | $0 | 0.00% | +67 | New |
| Strengthening Families & Communities, LLC | 1 | $0 | 0.00% | +1 | New |
| CIBC Private Wealth Group, LLC | 30,000 | $57 | 0.00% | 00.0% | Unchanged |
| Coppell Advisory Solutions LLC | 113 | $216 | 0.00% | +113 | New |
| Coppell Advisory Solutions Corp. | 113 | $216 | 0.00% | +113 | New |
| Advisory Services Network, LLC | 242 | $462 | 0.00% | +242 | New |
| Northwestern Mutual Wealth Management Co | 500 | $955 | 0.00% | 00.0% | Unchanged |
| Hall Laurie J Trustee | 720 | $1.00K | 0.00% | −420−36.8% | Reduced |
| Daiwa Securities Group Inc. | 434 | $1.00K | 0.00% | 00.0% | Unchanged |
| Farmers & Merchants Investments Inc | 1,000 | $1.91K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 1,918 | $3.66K | 0.00% | +199+11.6% | Added |
| Rockefeller Capital Management L.P. | 3,000 | $5.00K | 0.00% | +3,000 | New |
| Advisor Group Holdings, Inc. | 3,274 | $6.00K | 0.00% | −340−9.4% | Reduced |
| Aquatic Capital Management LLC | 4,000 | $8.00K | 0.00% | +4,000 | New |
| Citigroup Inc | 4,217 | $8.05K | 0.00% | −420−9.1% | Reduced |
| Great West Life Assurance Co | 4,635 | $9.00K | 0.00% | −32,708−87.6% | Reduced |
| Point72 Middle East FZE | 5,167 | $9.87K | 0.00% | +5,167 | New |
| Metropolitan Life Insurance Co | 5,205 | $9.94K | 0.00% | +111+2.2% | Added |
| Tower Research Capital LLC (TRC) | 6,324 | $12.0K | 0.00% | −13,065−67.4% | Reduced |
| Ameritas Investment Partners, Inc. | 5,367 | $12.0K | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 8,160 | $15.6K | 0.00% | −179−2.1% | Reduced |
| BNP Paribas Arbitrage, SA | 8,240 | $15.7K | 0.00% | −7,219−46.7% | Reduced |
| Estabrook Capital Management | 10,000 | $19.1K | 0.00% | 00.0% | Unchanged |
| Pegasus Asset Management, Inc. | 10,000 | $19.1K | 0.01% | 00.0% | Unchanged |
| Pinnacle Wealth Management Advisory Group, LLC | 10,420 | $19.9K | 0.00% | +280+2.8% | Added |
| Berger Financial Group, Inc | 10,929 | $20.9K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 11,037 | $21.0K | 0.00% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 11,361 | $21.6K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 12,620 | $24.0K | 0.00% | +11,585+1,119.3% | Added |
| Simplex Trading, LLC | 17,208 | $32.0K | 0.00% | +2,373+16.0% | Added |
| Acrisure Capital Management, LLC | 16,861 | $32.2K | 0.04% | +16,861 | New |
| Jane Street Group, LLC | 17,331 | $33.1K | 0.00% | −17,210−49.8% | Reduced |
| Cubist Systematic Strategies, LLC | 18,245 | $34.8K | 0.00% | −4,600−20.1% | Reduced |
| Victory Capital Management Inc | 20,423 | $39.0K | 0.00% | −100.0% | Reduced |
| LPL Financial LLC | 20,732 | $39.6K | 0.00% | +32+0.2% | Added |
| AXA S.A. | 20,900 | $39.9K | 0.00% | −91,268−81.4% | Reduced |
| Arizona State Retirement System | 21,301 | $40.7K | 0.00% | +1,344+6.7% | Added |
| MetLife Investment Management | 21,835 | $41.7K | 0.00% | −18,221−45.5% | Reduced |
| Barclays PLC | 22,360 | $42.7K | 0.00% | +18,829+533.2% | Added |
| Teacher Retirement System of Texas | 22,866 | $44.0K | 0.00% | −1,230−5.1% | Reduced |
| Commonwealth Equity Services, LLC | 24,469 | $46.0K | 0.00% | −107−0.4% | Reduced |
| Group One Trading, L.P. | 24,224 | $46.3K | 0.00% | −105,048−81.3% | Reduced |
| SG Americas Securities, LLC | 25,053 | $48.0K | 0.00% | −9,536−27.6% | Reduced |
| ProShare Advisors LLC | 26,324 | $50.3K | 0.00% | +1,699+6.9% | Added |
| Legal & General Group Plc | 26,653 | $50.9K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 27,264 | $52.1K | 0.00% | +27,264 | New |
| State Board of Administration of Florida Retirement System | 29,400 | $56.2K | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 32,681 | $62.4K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 33,626 | $64.2K | 0.00% | +87+0.3% | Added |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $68.0K | 0.03% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 35,943 | $68.7K | 0.00% | +20,065+126.4% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 36,480 | $69.7K | 0.00% | +23,792+187.5% | Added |
| Deutsche Bank AG | 36,646 | $70.0K | 0.00% | +556+1.5% | Added |
| Balyasny Asset Management LLC | 38,377 | $73.3K | 0.00% | +38,377 | New |
| American International Group, Inc. | 39,393 | $75.2K | 0.00% | −143−0.4% | Reduced |
| Principal Financial Group Inc | 41,211 | $78.7K | 0.00% | +31,205+311.9% | Added |
| Invesco Ltd. | 41,223 | $78.7K | 0.00% | +9,870+31.5% | Added |
| Caxton Associates LP | 46,281 | $88.4K | 0.01% | −8,500−15.5% | Reduced |
| AQR Capital Management LLC | 47,014 | $89.8K | 0.00% | −253,205−84.3% | Reduced |
| Susquehanna International Group, LLP | 48,855 | $93.3K | 0.00% | −30,497−38.4% | Reduced |
| Bank of America Corp | 62,471 | $119.3K | 0.00% | −47,662−43.3% | Reduced |
| Credit Suisse AG | 63,365 | $121.0K | 0.00% | +23,882+60.5% | Added |
| State of Wisconsin Investment Board | 70,843 | $135.3K | 0.00% | −4,244−5.7% | Reduced |
| Prudential Financial Inc | 85,358 | $163.0K | 0.00% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 89,811 | $171.5K | 0.00% | +4,800+5.6% | Added |
| Compagnie Lombard Odier SCmA | 98,000 | $187.0K | 0.01% | 00.0% | Unchanged |
| California State Teachers Retirement System | 99,239 | $189.5K | 0.00% | +3,179+3.3% | Added |
| Two Sigma Investments, LP | 115,231 | $220.1K | 0.00% | +71,934+166.1% | Added |
| Schonfeld Strategic Advisors LLC | 117,000 | $223.5K | 0.00% | +117,000 | New |
| UBS Asset Management Americas Inc | 119,046 | $227.4K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 119,117 | $228.0K | 0.00% | +5,722+5.0% | Added |
| Stifel Financial Corp | 124,484 | $237.8K | 0.00% | −12,199−8.9% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 134,557 | $257.0K | 0.00% | +134,557 | New |
| Morgan Stanley | 135,842 | $259.5K | 0.00% | −33,241−19.7% | Reduced |
| Wellington Management Group LLP | 155,906 | $297.8K | 0.00% | +263+0.2% | Added |
| UBS Group AG | 159,818 | $305.3K | 0.00% | +66,132+70.6% | Added |
| Citadel Advisors LLC | 162,176 | $309.8K | 0.00% | +34,983+27.5% | Added |
| Swiss National Bank | 182,300 | $348.2K | 0.00% | +9,500+5.5% | Added |
| Price T Rowe Associates Inc | 194,113 | $371.0K | 0.00% | +838+0.4% | Added |
| Nuveen Asset Management, LLC | 244,650 | $467.0K | 0.00% | −61,866−20.2% | Reduced |
| Russell Investments Group, Ltd. | 248,414 | $474.5K | 0.00% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 266,357 | $508.7K | 0.00% | +25,436+10.6% | Added |
| Bank of New York Mellon Corp | 326,018 | $622.7K | 0.00% | +34,358+11.8% | Added |
| ClariVest Asset Management LLC | 389,760 | $744.0K | 0.04% | −3,031−0.8% | Reduced |
| Renaissance Technologies LLC | 393,285 | $751.0K | 0.00% | −88,090−18.3% | Reduced |
| Dimensional Fund Advisors LP | 412,798 | $788.0K | 0.00% | −50,390−10.9% | Reduced |
| Parkman Healthcare Partners LLC | 421,202 | $804.5K | 0.21% | +117,588+38.7% | Added |
| Charles Schwab Investment Management Inc | 695,940 | $1.33M | 0.00% | +33,462+5.1% | Added |
| Fisher Asset Management, LLC | 720,243 | $1.38M | 0.00% | +114,715+18.9% | Added |
| Northern Trust Corp | 786,971 | $1.50M | 0.00% | +51,461+7.0% | Added |
| Millennium Management LLC | 1,176,567 | $2.25M | 0.00% | +270,656+29.9% | Added |
| Point72 Asset Management, L.P. | 1,344,131 | $2.57M | 0.01% | −2,269,369−62.8% | Reduced |
| State Street Corp | 1,516,475 | $2.90M | 0.00% | +52,906+3.6% | Added |
| Geode Capital Management, LLC | 1,607,941 | $3.07M | 0.00% | +38,919+2.5% | Added |
| Pinnacle Associates Ltd | 1,932,777 | $3.69M | 0.08% | −98,430−4.8% | Reduced |
| NEA Management Company, LLC | 2,382,286 | $4.55M | 0.26% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 3,077,973 | $5.88M | 0.01% | +33,996+1.1% | Added |
| JPMorgan Chase & Co | 3,276,798 | $6.26M | 0.00% | +50,365+1.6% | Added |
| FMR LLC | 5,251,685 | $10.0M | 0.00% | −31,314−0.6% | Reduced |