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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
104
−1 vs. Q4 2022
Shares held
145.6M
−1.28M (−0.9%) vs. Q4 2022
Total value
$353.8M
+$73.3M (+26.1%) vs. Q4 2022
New holders
14
37 more added
Sold out
15
34 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 104 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ1 2023: $353.8M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2022.

Institutions holding LXRX in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Nisa Investment Advisors, LLC67$00.00%00.0%Unchanged
Avion Wealth407$00.00%00.0%Unchanged
Advisory Services Network, LLC242$5880.00%00.0%Unchanged
Daiwa Securities Group Inc.434$1.00K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co500$1.22K0.00%00.0%Unchanged
Global Retirement Partners, LLC1,000$2.74K0.00%+1,000New
Quintet Private Bank (Europe) S.A.1,930$4.69K0.00%+1,930New
China Universal Asset Management Co., Ltd.2,557$6.21K0.00%+639+33.3%Added
Advisor Group Holdings, Inc.2,882$7.00K0.00%−392−12.0%Reduced
Citigroup Inc4,045$9.83K0.00%−172−4.1%Reduced
Royal Bank of Canada4,660$11.0K0.00%−7,960−63.1%Reduced
Metropolitan Life Insurance Co4,595$11.2K0.00%−610−11.7%Reduced
Tower Research Capital LLC (TRC)5,611$13.0K0.00%−713−11.3%Reduced
Ameritas Investment Partners, Inc.5,367$13.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC5,922$14.4K0.00%−12,323−67.5%Reduced
Amalgamated Bank9,111$22.0K0.00%−1,926−17.5%Reduced
Estabrook Capital Management10,000$24.3K0.00%00.0%Unchanged
Pegasus Asset Management, Inc.10,000$24.3K0.01%00.0%Unchanged
Berger Financial Group, Inc10,929$26.6K0.00%00.0%Unchanged
Tudor Investment Corp Et Al11,000$27.0K0.00%+11,000New
Pinnacle Wealth Management Advisory Group, LLC11,385$27.7K0.00%+965+9.3%Added
Commonwealth Equity Services, LLC14,069$34.0K0.00%−10,400−42.5%Reduced
Beacon Pointe Advisors, LLC15,000$36.5K0.00%+15,000New
Hudson Capital Management LLC15,038$36.5K0.01%+15,038New
Wells Fargo & Company15,363$37.3K0.00%+15,363New
ExodusPoint Capital Management, LP15,536$38.0K0.00%+15,536New
Jump Financial, LLC18,200$44.2K0.00%+18,200New
BNP Paribas Arbitrage, SA18,552$45.1K0.00%+10,312+125.1%Added
Traynor Capital Management, Inc.19,064$46.3K0.01%+19,064New
Victory Capital Management Inc20,723$50.4K0.00%+300+1.5%Added
LPL Financial LLC20,732$50.4K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)20,787$50.5K0.00%−15,693−43.0%Reduced
Virtu Financial LLC21,729$53.0K0.01%+21,729New
Arizona State Retirement System21,873$53.2K0.00%+572+2.7%Added
ProShare Advisors LLC22,886$55.6K0.00%−3,438−13.1%Reduced
Teacher Retirement System of Texas23,255$57.0K0.00%+389+1.7%Added
Millennium Management LLC23,844$58.0K0.00%−1,152,723−98.0%Reduced
Squarepoint Ops LLC23,938$58.2K0.00%−3,326−12.2%Reduced
Janus Henderson Group PLC28,630$69.4K0.00%+17,269+152.0%Added
State Board of Administration of Florida Retirement System29,400$71.4K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC30,000$72.9K0.00%00.0%Unchanged
Legal & General Group Plc30,056$73.0K0.00%+3,403+12.8%Added
Voya Investment Management LLC32,681$79.4K0.00%00.0%Unchanged
Group One Trading, L.P.33,513$81.4K0.00%+9,289+38.3%Added
New York State Common Retirement Fund33,626$81.7K0.00%00.0%Unchanged
University of Texas/Texas Am Investment Managment Co35,714$87.0K0.03%00.0%Unchanged
Manufacturers Life Insurance Company, The35,943$87.3K0.00%00.0%Unchanged
SG Americas Securities, LLC37,689$92.0K0.00%+12,636+50.4%Added
American International Group, Inc.40,193$97.7K0.00%+800+2.0%Added
Principal Financial Group Inc40,544$98.5K0.00%−667−1.6%Reduced
Invesco Ltd.40,972$99.6K0.00%−251−0.6%Reduced
Barclays PLC42,296$102.8K0.00%+19,936+89.2%Added
MetLife Investment Management42,834$104.1K0.00%+20,999+96.2%Added
Jane Street Group, LLC43,523$105.8K0.00%+26,192+151.1%Added
Simplex Trading, LLC45,624$110.0K0.00%+28,416+165.1%Added
Captrust Financial Advisors46,489$113.0K0.00%+46,489New
Deutsche Bank AG52,625$127.9K0.00%+15,979+43.6%Added
Susquehanna International Group, LLP53,293$129.5K0.00%+4,438+9.1%Added
Great West Life Assurance Co54,172$131.0K0.00%+49,537+1,068.8%Added
Russell Investments Group, Ltd.55,327$134.4K0.00%−193,087−77.7%Reduced
Qube Research & Technologies Ltd60,723$147.6K0.00%+60,723New
Bank of America Corp60,761$147.6K0.00%−1,710−2.7%Reduced
Credit Suisse AG63,385$154.0K0.00%+200.0%Added
State of Wisconsin Investment Board63,765$154.9K0.00%−7,078−10.0%Reduced
Gsa Capital Partners LLP69,791$170.0K0.02%+69,791New
Natixis Advisors, L.P.87,505$213.0K0.00%+87,505New
Alliancebernstein L.P.93,411$227.0K0.00%+3,600+4.0%Added
Compagnie Lombard Odier SCmA94,000$228.4K0.01%−4,000−4.1%Reduced
California State Teachers Retirement System97,279$236.4K0.00%−1,960−2.0%Reduced
Prudential Financial Inc101,158$245.8K0.00%+15,800+18.5%Added
Citadel Advisors LLC110,829$269.3K0.00%−51,347−31.7%Reduced
Rhumbline Advisers125,066$304.0K0.00%+5,949+5.0%Added
Stifel Financial Corp128,311$311.8K0.00%+3,827+3.1%Added
UBS Asset Management Americas Inc137,735$334.7K0.00%+18,689+15.7%Added
UBS Group AG138,726$337.1K0.00%−21,092−13.2%Reduced
Wellington Management Group LLP151,493$368.1K0.00%−4,413−2.8%Reduced
Price T Rowe Associates Inc156,621$381.0K0.00%−37,492−19.3%Reduced
Schonfeld Strategic Advisors LLC159,000$386.4K0.00%+42,000+35.9%Added
Swiss National Bank162,900$395.8K0.00%−19,400−10.6%Reduced
Morgan Stanley198,304$481.9K0.00%+62,462+46.0%Added
Nuveen Asset Management, LLC201,514$489.0K0.00%−43,136−17.6%Reduced
Connor, Clark & Lunn Investment Management Ltd.208,333$506.2K0.00%+73,776+54.8%Added
Renaissance Technologies LLC263,875$641.0K0.00%−129,410−32.9%Reduced
Goldman Sachs Group Inc288,938$702.1K0.00%+22,581+8.5%Added
Bank of New York Mellon Corp317,502$771.5K0.00%−8,516−2.6%Reduced
AXA S.A.356,400$866.1K0.00%+335,500+1,605.3%Added
ClariVest Asset Management LLC390,161$949.0K0.04%+401+0.1%Added
Point72 Asset Management, L.P.516,367$1.25M0.00%−827,764−61.6%Reduced
Fisher Asset Management, LLC649,726$1.58M0.00%−70,517−9.8%Reduced
Parkman Healthcare Partners LLC675,328$1.64M0.36%+254,126+60.3%Added
Charles Schwab Investment Management Inc688,611$1.67M0.00%−7,329−1.1%Reduced
Dimensional Fund Advisors LP719,182$1.75M0.00%+306,384+74.2%Added
Northern Trust Corp763,264$1.85M0.00%−23,707−3.0%Reduced
State Street Corp1,564,098$3.80M0.00%+47,623+3.1%Added
Geode Capital Management, LLC1,725,409$4.19M0.00%+117,468+7.3%Added
Pinnacle Associates Ltd1,940,224$4.71M0.10%+7,447+0.4%Added
NEA Management Company, LLC2,382,286$5.79M0.40%00.0%Unchanged
D. E. Shaw & Co., Inc.2,940,997$7.15M0.01%−136,976−4.5%Reduced
JPMorgan Chase & Co3,305,991$8.03M0.00%+29,193+0.9%Added
FMR LLC5,240,247$12.7M0.00%−11,438−0.2%Reduced