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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
98
+13 vs. Q2 2022
Shares held
148.9M
+30.1M (+25.3%) vs. Q2 2022
Total value
$357.3M
+$136.3M (+61.7%) vs. Q2 2022
New holders
21
38 more added
Sold out
8
22 more reduced

1 institution that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 98 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ3 2022: $357.3M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q2 2022.

Institutions holding LXRX in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Dark Forest Capital Management LP35$00.00%+35New
Northwestern Mutual Wealth Management Co500$1.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.434$1.00K0.00%00.0%Unchanged
Avion Wealth407$1.00K0.00%00.0%Unchanged
Wells Fargo & Company761$2.00K0.00%−566−42.7%Reduced
Royal Bank of Canada1,035$2.00K0.00%+115+12.5%Added
Farmers & Merchants Investments Inc1,000$2.00K0.00%00.0%Unchanged
Hall Laurie J Trustee1,140$3.00K0.00%−510−30.9%Reduced
China Universal Asset Management Co., Ltd.1,719$4.00K0.00%+1,719New
Barclays PLC3,531$8.00K0.00%−71,723−95.3%Reduced
Advisor Group Holdings, Inc.3,614$8.00K0.00%+1,023+39.5%Added
Citigroup Inc4,637$11.0K0.00%−11,916−72.0%Reduced
Ameritas Investment Partners, Inc.5,367$12.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co5,094$12.2K0.00%+5,094New
Allspring Global Investments Holdings, LLC8,339$20.0K0.00%−8,685−51.0%Reduced
Pegasus Asset Management, Inc.10,000$24.0K0.01%00.0%Unchanged
Estabrook Capital Management10,000$24.0K0.00%00.0%Unchanged
Principal Financial Group Inc10,006$24.0K0.00%+10,006New
Pinnacle Wealth Management Advisory Group, LLC10,140$24.0K0.00%+10,140New
Berger Financial Group, Inc10,929$26.0K0.00%00.0%Unchanged
Amalgamated Bank11,037$26.0K0.00%+1,113+11.2%Added
Janus Henderson Group PLC11,361$27.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)12,688$30.0K0.00%00.0%Unchanged
Virtu Financial LLC13,458$32.0K0.00%+13,458New
Simplex Trading, LLC14,835$35.0K0.00%+10,766+264.6%Added
BNP Paribas Arbitrage, SA15,459$37.1K0.00%−644−4.0%Reduced
Manufacturers Life Insurance Company, The15,878$38.1K0.00%+15,878New
Tower Research Capital LLC (TRC)19,389$46.0K0.00%+13,232+214.9%Added
Arizona State Retirement System19,957$48.0K0.00%+3,741+23.1%Added
Victory Capital Management Inc20,433$49.0K0.00%+8,873+76.8%Added
LPL Financial LLC20,700$50.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC22,845$55.0K0.00%+22,845New
Commonwealth Equity Services, LLC24,576$58.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas24,096$58.0K0.00%+24,096New
ProShare Advisors LLC24,625$59.0K0.00%+4,793+24.2%Added
Legal & General Group Plc26,653$64.0K0.00%+7,805+41.4%Added
State Board of Administration of Florida Retirement System29,400$71.0K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC30,000$72.0K0.00%+30,000New
Invesco Ltd.31,353$75.0K0.00%+2,830+9.9%Added
Voya Investment Management LLC32,681$78.4K0.00%+6,330+24.0%Added
New York State Common Retirement Fund33,539$80.0K0.00%+197+0.6%Added
SG Americas Securities, LLC34,589$83.0K0.00%−878−2.5%Reduced
Jane Street Group, LLC34,541$83.0K0.00%+34,541New
University of Texas/Texas Am Investment Managment Co35,714$86.0K0.03%00.0%Unchanged
Deutsche Bank AG36,090$87.0K0.00%+2,998+9.1%Added
Great West Life Assurance Co37,343$89.0K0.00%+32,708+705.7%Added
Credit Suisse AG39,483$95.0K0.00%+508+1.3%Added
American International Group, Inc.39,536$95.0K0.00%+5,444+16.0%Added
MetLife Investment Management40,056$96.1K0.00%+40,056New
Two Sigma Investments, LP43,297$104.0K0.00%+43,297New
HRT Financial LP45,569$109.0K0.00%+45,569New
Caxton Associates LP54,781$131.0K0.02%+54,781New
Gsa Capital Partners LLP71,004$170.0K0.02%−300,594−80.9%Reduced
State of Wisconsin Investment Board75,087$180.0K0.00%+60,519+415.4%Added
Susquehanna International Group, LLP79,352$190.0K0.00%−14,599−15.5%Reduced
Norges Bank82,900$199.0K0.00%+82,900New
Alliancebernstein L.P.85,011$204.0K0.00%+28,400+50.2%Added
Prudential Financial Inc85,358$205.0K0.00%−39,150−31.4%Reduced
Natixis Advisors, L.P.88,411$212.0K0.00%+88,411New
UBS Group AG93,686$225.0K0.00%−118,467−55.8%Reduced
California State Teachers Retirement System96,060$231.0K0.00%+14,835+18.3%Added
Compagnie Lombard Odier SCmA98,000$235.0K0.01%00.0%Unchanged
Bank of America Corp110,133$264.0K0.00%+71,823+187.5%Added
AXA S.A.112,168$269.2K0.00%+91,268+436.7%Added
Rhumbline Advisers113,395$272.0K0.00%+15,925+16.3%Added
UBS Asset Management Americas Inc119,046$285.7K0.00%−56,904−32.3%Reduced
Citadel Advisors LLC127,193$306.0K0.00%−38,486−23.2%Reduced
Group One Trading, L.P.129,272$310.0K0.01%+34,672+36.7%Added
Stifel Financial Corp136,683$328.0K0.00%−2,694−1.9%Reduced
Wellington Management Group LLP155,643$374.0K0.00%−61,554−28.3%Reduced
Morgan Stanley169,083$405.0K0.00%−399,825−70.3%Reduced
Swiss National Bank172,800$415.0K0.00%+32,000+22.7%Added
Price T Rowe Associates Inc193,275$464.0K0.00%−4,166−2.1%Reduced
Goldman Sachs Group Inc240,921$578.0K0.00%+32,896+15.8%Added
Russell Investments Group, Ltd.248,414$595.0K0.00%−1,903−0.8%Reduced
Bank of New York Mellon Corp291,660$699.0K0.00%+34,564+13.4%Added
AQR Capital Management LLC300,219$721.0K0.00%+300,219New
Parkman Healthcare Partners LLC303,614$729.0K0.21%+53,614+21.4%Added
Nuveen Asset Management, LLC306,516$736.0K0.00%+56,582+22.6%Added
ClariVest Asset Management LLC392,791$943.0K0.05%+392,791New
Dimensional Fund Advisors LP463,188$1.11M0.00%−201,600−30.3%Reduced
Renaissance Technologies LLC481,375$1.16M0.00%+481,375New
Fisher Asset Management, LLC605,528$1.45M0.00%00.0%Unchanged
Charles Schwab Investment Management Inc662,478$1.59M0.00%+227,914+52.4%Added
Northern Trust Corp735,510$1.76M0.00%+63,047+9.4%Added
Millennium Management LLC905,911$2.17M0.00%+687,963+315.7%Added
State Street Corp1,463,569$3.51M0.00%+111,568+8.3%Added
Geode Capital Management, LLC1,569,022$3.77M0.00%+227,609+17.0%Added
Pinnacle Associates Ltd2,031,207$4.88M0.11%−56,256−2.7%Reduced
NEA Management Company, LLC2,382,286$5.72M0.29%00.0%Unchanged
D. E. Shaw & Co., Inc.3,043,977$7.31M0.01%−184,095−5.7%Reduced
JPMorgan Chase & Co3,226,433$7.74M0.00%+2,093,656+184.8%Added
Point72 Asset Management, L.P.3,613,500$8.67M0.04%+3,613,500New
Vanguard Group Inc5,256,288$12.6M0.00%+1,334,318+34.0%Added
FMR LLC5,282,999$12.7M0.00%−7,615−0.1%Reduced
BlackRock Inc.5,760,000$13.8M0.00%+1,240,171+27.4%Added
BVF Inc16,149,179$38.8M1.60%+2,000,000+14.1%Added
Artal Group S.A.89,778,234$215.5M11.25%+18,599,870+26.1%Added
Integral Health Asset Management, LLC0$00.00%−300,000−100.0%Sold out
Nomura Holdings Inc0$00.00%−212,620−100.0%Sold out