Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- −9 vs. Q3 2024
- Shares held
- 297.7M
- +9.07M (+3.1%) vs. Q3 2024
- Total value
- $220.1M
- −$232.9M (−51.4%) vs. Q3 2024
- New holders
- 25
- 45 more added
- Sold out
- 34
- 24 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| R Squared Ltd | 3,040 | $2.25K | 0.00% | +3,040 | New |
| Amalgamated Bank | 2,409 | $2.00K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 2,477 | $1.83K | 0.00% | +2,205+810.7% | Added |
| Manchester Capital Management LLC | 2,380 | $1.76K | 0.00% | 00.0% | Unchanged |
| Quintet Private Bank (Europe) S.A. | 1,928 | $1.42K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 1,624 | $1.20K | 0.00% | +1,624 | New |
| Daiwa Securities Group Inc. | 1,369 | $1.00K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 1,131 | $1.00K | 0.00% | +1,031+1,031.0% | Added |
| Optiver Holding B.V. | 1,200 | $886 | 0.00% | +1,200 | New |
| Global Retirement Partners, LLC | 1,000 | $739 | 0.00% | 00.0% | Unchanged |
| Pinney & Scofield, Inc. | 1,000 | $739 | 0.00% | +1,000 | New |
| Advisor Group Holdings, Inc. | 742 | $549 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 500 | $369 | 0.00% | 00.0% | Unchanged |
| SJS Investment Consulting Inc. | 400 | $296 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 400 | $295 | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 388 | $287 | 0.00% | −786−67.0% | Reduced |
| Syntax Research, Inc. | 142 | $105 | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 142 | $105 | 0.00% | +142 | New |
| Comerica Bank | 122 | $90 | 0.00% | +122 | New |
| The PNC Financial Services Group, Inc. | 111 | $82 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 100 | $74 | 0.00% | 00.0% | Unchanged |
| CBIZ Investment Advisory Services, LLC | 71 | $52 | 0.00% | +71 | New |
| Coppell Advisory Solutions LLC | 52 | $37 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 32 | $24 | 0.00% | +32 | New |
| GWM Advisors LLC | 5 | $4 | 0.00% | +5 | New |
| Farther Finance Advisors, LLC | 2 | $1 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 81 | $0 | 0.00% | +15+22.7% | Added |
| OrbiMed Advisors LLC | 0 | $0 | 0.00% | −11,024,000−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −2,327,110−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −1,398,876−100.0% | Sold out |
| Braidwell LP | 0 | $0 | 0.00% | −801,584−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −574,150−100.0% | Sold out |
| Knott David M Jr | 0 | $0 | 0.00% | −500,000−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −204,879−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −188,842−100.0% | Sold out |
| Deerfield Management Company, L.P. (Series C) | 0 | $0 | 0.00% | −156,860−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −80,423−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −77,733−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −58,007−100.0% | Sold out |
| MetLife Investment Management | 0 | $0 | 0.00% | −55,182−100.0% | Sold out |
| CIBC Private Wealth Group, LLC | 0 | $0 | 0.00% | −50,010−100.0% | Sold out |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −49,100−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −24,527−100.0% | Sold out |
| Cetera Investment Advisers | 0 | $0 | 0.00% | −21,775−100.0% | Sold out |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Cresset Asset Management, LLC | 0 | $0 | 0.00% | −15,120−100.0% | Sold out |
| Prosperity Financial Group, Inc. | 0 | $0 | 0.00% | −14,437−100.0% | Sold out |
| Perennial Investment Advisors, LLC | 0 | $0 | 0.00% | −11,600−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −11,338−100.0% | Sold out |
| Wolverine Trading, LLC | 0 | $0 | 0.00% | −11,192−100.0% | Sold out |
| River Wealth Advisors LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Legacy Capital Wealth Partners, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| LifeSteps Financial, Inc. | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −2,205−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −1,371−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −639−100.0% | Sold out |
| Nisa Investment Advisors, LLC | 0 | $0 | 0.00% | −147−100.0% | Sold out |
| Tortoise Investment Management, LLC | 0 | $0 | 0.00% | −21−100.0% | Sold out |
| Capital Performance Advisors LLP | 0 | $0 | 0.00% | −18−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −6−100.0% | Sold out |
| Avion Wealth | 0 | $0 | 0.00% | −407−100.0% | Sold out |
| Raymond James & Associates | – | – | – | – | Not filed |