Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- +2 vs. Q4 2024
- Shares held
- 265.8M
- −30.8M (−10.4%) vs. Q4 2024
- Total value
- $122.5M
- −$96.9M (−44.2%) vs. Q4 2024
- New holders
- 31
- 34 more added
- Sold out
- 29
- 32 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 81 | $0 | 0.00% | 00.0% | Unchanged |
| Avion Wealth | 1,134 | $0 | 0.00% | +1,134 | New |
| Farther Finance Advisors, LLC | 2 | $1 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 5 | $2 | 0.00% | 00.0% | Unchanged |
| CBIZ Investment Advisory Services, LLC | 71 | $33 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 100 | $46 | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 122 | $56 | 0.00% | 00.0% | Unchanged |
| Syntax Research, Inc. | 142 | $66 | 0.00% | 00.0% | Unchanged |
| SJS Investment Consulting Inc. | 400 | $185 | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 406 | $187 | 0.00% | −25,426−98.4% | Reduced |
| Northwestern Mutual Wealth Management Co | 500 | $230 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 600 | $276 | 0.00% | +600 | New |
| True Wealth Design, LLC | 619 | $286 | 0.00% | +619 | New |
| EverSource Wealth Advisors, LLC | 930 | $429 | 0.00% | +898+2,806.3% | Added |
| Advisor Group Holdings, Inc. | 942 | $433 | 0.00% | +200+27.0% | Added |
| Pinney & Scofield, Inc. | 1,000 | $461 | 0.00% | 00.0% | Unchanged |
| US Bancorp | 1,082 | $499 | 0.00% | −542−33.4% | Reduced |
| Sterling Capital Management LLC | 1,280 | $590 | 0.00% | −1,197−48.3% | Reduced |
| Rialto Wealth Management, LLC | 1,313 | $606 | 0.00% | +1,313 | New |
| Coldstream Capital Management Inc | 1,388 | $640 | 0.00% | +1,388 | New |
| The PNC Financial Services Group, Inc. | 1,461 | $673 | 0.00% | +1,350+1,216.2% | Added |
| Optiver Holding B.V. | 1,843 | $849 | 0.00% | +643+53.6% | Added |
| Quintet Private Bank (Europe) S.A. | 1,928 | $888 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 3,159 | $1.00K | 0.00% | −6,752−68.1% | Reduced |
| Amalgamated Bank | 2,409 | $1.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 1,369 | $1.00K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 2,042 | $1.16K | 0.00% | +1,900+1,338.0% | Added |
| SBI Securities Co., Ltd. | 3,320 | $1.53K | 0.00% | +256+8.4% | Added |
| Golden State Wealth Management, LLC | 3,700 | $1.71K | 0.00% | +3,700 | New |
| California State Teachers Retirement System | 8,319 | $3.83K | 0.00% | −186,896−95.7% | Reduced |
| Ameritas Investment Partners, Inc. | 8,867 | $4.09K | 0.00% | 00.0% | Unchanged |
| Unique Wealth Strategies, LLC | 10,000 | $4.61K | 0.00% | 00.0% | Unchanged |
| Berger Financial Group, Inc | 10,929 | $5.04K | 0.00% | 00.0% | Unchanged |
| Chaney Capital Management, Inc. | 11,167 | $5.15K | 0.00% | +11,167 | New |
| Legal & General Group Plc | 11,466 | $5.28K | 0.00% | −99,937−89.7% | Reduced |
| North Star Asset Management Inc | 11,500 | $5.30K | 0.00% | 00.0% | Unchanged |
| Avantax Advisory Services, Inc. | 11,724 | $5.40K | 0.00% | +11,724 | New |
| Raymond James Financial Inc | 11,912 | $5.49K | 0.00% | 00.0% | Unchanged |
| Chemistry Wealth Management LLC | 12,000 | $5.53K | 0.00% | 00.0% | Unchanged |
| Buckingham Strategic Partners | 12,096 | $5.61K | 0.00% | +12,096 | New |
| XTX Topco Ltd | 12,471 | $5.75K | 0.00% | +12,471 | New |
| Point72 (DIFC) Ltd | 13,327 | $6.14K | 0.00% | +13,327 | New |
| Cubist Systematic Strategies, LLC | 13,797 | $6.36K | 0.00% | +13,797 | New |
| Voya Investment Management LLC | 13,922 | $6.42K | 0.00% | −24,496−63.8% | Reduced |
| Truist Financial Corp | 14,000 | $6.45K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 12,096 | $6.90K | 0.00% | +50+0.4% | Added |
| Merit Financial Group, LLC | 15,492 | $7.14K | 0.00% | +15,492 | New |
| HSBC Holdings PLC | 13,415 | $7.76K | 0.00% | −87−0.6% | Reduced |
| Ethic Inc. | 17,259 | $8.01K | 0.00% | +17,259 | New |
| Tiaa Trust, National Association | 20,000 | $9.22K | 0.00% | 00.0% | Unchanged |
| Invera Wealth Advisors, LLC | 20,000 | $9.22K | 0.01% | +20,000 | New |
| Oppenheimer & Co Inc | 20,100 | $9.26K | 0.00% | +20,100 | New |
| Simplicity Wealth,LLC | 20,447 | $9.42K | 0.00% | +20,447 | New |
| Steward Partners Investment Advisory, LLC | 21,323 | $9.83K | 0.00% | +20,923+5,230.8% | Added |
| Victory Capital Management Inc | 21,633 | $9.97K | 0.00% | +774+3.7% | Added |
| Cambridge Investment Research Advisors, Inc. | 22,075 | $10.0K | 0.00% | −1,538−6.5% | Reduced |
| SIH Partners, LLLP | 23,712 | $10.9K | 0.00% | +23,712 | New |
| CIBC World Markets Corp | 25,477 | $11.7K | 0.00% | +14,733+137.1% | Added |
| Tower Research Capital LLC (TRC) | 28,107 | $13.0K | 0.00% | +15,952+131.2% | Added |
| Police & Firemen's Retirement System of New Jersey | 29,715 | $13.7K | 0.00% | 00.0% | Unchanged |
| Pathstone Holdings, LLC | 31,397 | $14.5K | 0.00% | −22,654−41.9% | Reduced |
| Captrust Financial Advisors | 33,184 | $15.3K | 0.00% | +19,826+148.4% | Added |
| New York State Common Retirement Fund | 33,702 | $15.5K | 0.00% | 00.0% | Unchanged |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $16.5K | 0.00% | 00.0% | Unchanged |
| Pallas Capital Advisors LLC | 36,208 | $16.7K | 0.00% | +36,208 | New |
| JustInvest LLC | 36,736 | $16.9K | 0.00% | +13,513+58.2% | Added |
| Fortis Group Advisors, LLC | 37,800 | $17.4K | 0.00% | +37,800 | New |
| ProShare Advisors LLC | 41,162 | $19.0K | 0.00% | −8,298−16.8% | Reduced |
| Wedbush Securities Inc | 40,850 | $19.0K | 0.00% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 54,180 | $25.0K | 0.00% | −1,371,112−96.2% | Reduced |
| Corebridge Financial, Inc. | 56,248 | $25.9K | 0.00% | −834−1.5% | Reduced |
| Straight Path Wealth Management | 62,666 | $28.9K | 0.01% | +62,666 | New |
| Wells Fargo & Company | 63,928 | $29.5K | 0.00% | +1,405+2.2% | Added |
| KWB Wealth | 40,640 | $30.0K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 68,012 | $31.0K | 0.00% | +12,704+23.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 68,683 | $31.6K | 0.00% | +2,901+4.4% | Added |
| Wealth Enhancement Advisory Services, LLC | 69,207 | $31.9K | 0.00% | +69,207 | New |
| LPL Financial LLC | 70,957 | $32.7K | 0.00% | +13,950+24.5% | Added |
| China Universal Asset Management Co., Ltd. | 72,509 | $33.4K | 0.00% | −4,141−5.4% | Reduced |
| Intech Investment Management LLC | 73,853 | $34.0K | 0.00% | +17,164+30.3% | Added |
| JPMorgan Chase & Co | 88,199 | $40.6K | 0.00% | +582+0.7% | Added |
| BNP Paribas Arbitrage, SA | 89,114 | $41.1K | 0.00% | +69,410+352.3% | Added |
| Commonwealth Equity Services, LLC | 90,864 | $42.0K | 0.00% | −10,284−10.2% | Reduced |
| Price T Rowe Associates Inc | 92,248 | $43.0K | 0.00% | +14,746+19.0% | Added |
| Deutsche Bank AG | 94,394 | $43.4K | 0.00% | −221,265−70.1% | Reduced |
| Bank of America Corp | 96,387 | $44.3K | 0.00% | −40,020−29.3% | Reduced |
| Citigroup Inc | 96,968 | $44.7K | 0.00% | −9,818−9.2% | Reduced |
| Bank of Montreal | 100,000 | $46.1K | 0.00% | +30,000+42.9% | Added |
| CWM, LLC | 105,504 | $49.0K | 0.00% | +104,373+9,228.4% | Added |
| Compagnie Lombard Odier SCmA | 110,000 | $50.7K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 137,230 | $63.3K | 0.00% | −15,921−10.4% | Reduced |
| Barclays PLC | 146,071 | $67.3K | 0.00% | −97,245−40.0% | Reduced |
| Cerity Partners LLC | 170,387 | $78.5K | 0.00% | +73,875+76.5% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 171,147 | $78.9K | 0.02% | +171,147 | New |
| Simplex Trading, LLC | 174,982 | $80.0K | 0.00% | +78,899+82.1% | Added |
| Ieq Capital, LLC | 177,302 | $81.7K | 0.00% | +177,302 | New |
| Squarepoint Ops LLC | 195,409 | $90.0K | 0.00% | +195,409 | New |
| Alliancebernstein L.P. | 246,121 | $113.4K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 285,759 | $131.7K | 0.00% | +181,265+173.5% | Added |
| Bank of New York Mellon Corp | 310,119 | $142.9K | 0.00% | −4,800−1.5% | Reduced |