Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- +2 vs. Q4 2024
- Shares held
- 265.8M
- −30.8M (−10.4%) vs. Q4 2024
- Total value
- $122.5M
- −$96.9M (−44.2%) vs. Q4 2024
- New holders
- 31
- 34 more added
- Sold out
- 29
- 32 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Jones Financial Companies LLLP | 2,042 | $1.16K | 0.00% | +1,900+1,338.0% | Added |
| Royal Bank of Canada | 3,159 | $1.00K | 0.00% | −6,752−68.1% | Reduced |
| Amalgamated Bank | 2,409 | $1.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 1,369 | $1.00K | 0.00% | 00.0% | Unchanged |
| Quintet Private Bank (Europe) S.A. | 1,928 | $888 | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 1,843 | $849 | 0.00% | +643+53.6% | Added |
| The PNC Financial Services Group, Inc. | 1,461 | $673 | 0.00% | +1,350+1,216.2% | Added |
| Coldstream Capital Management Inc | 1,388 | $640 | 0.00% | +1,388 | New |
| Rialto Wealth Management, LLC | 1,313 | $606 | 0.00% | +1,313 | New |
| Sterling Capital Management LLC | 1,280 | $590 | 0.00% | −1,197−48.3% | Reduced |
| US Bancorp | 1,082 | $499 | 0.00% | −542−33.4% | Reduced |
| Pinney & Scofield, Inc. | 1,000 | $461 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 942 | $433 | 0.00% | +200+27.0% | Added |
| EverSource Wealth Advisors, LLC | 930 | $429 | 0.00% | +898+2,806.3% | Added |
| True Wealth Design, LLC | 619 | $286 | 0.00% | +619 | New |
| Nisa Investment Advisors, LLC | 600 | $276 | 0.00% | +600 | New |
| Northwestern Mutual Wealth Management Co | 500 | $230 | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 406 | $187 | 0.00% | −25,426−98.4% | Reduced |
| SJS Investment Consulting Inc. | 400 | $185 | 0.00% | 00.0% | Unchanged |
| Syntax Research, Inc. | 142 | $66 | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 122 | $56 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 100 | $46 | 0.00% | 00.0% | Unchanged |
| CBIZ Investment Advisory Services, LLC | 71 | $33 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 5 | $2 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 2 | $1 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 81 | $0 | 0.00% | 00.0% | Unchanged |
| Avion Wealth | 1,134 | $0 | 0.00% | +1,134 | New |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −8,988,421−100.0% | Sold out |
| NEA Management Company, LLC | 0 | $0 | 0.00% | −2,382,286−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −747,996−100.0% | Sold out |
| Swiss National Bank | 0 | $0 | 0.00% | −426,600−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −425,269−100.0% | Sold out |
| UBS Asset Management Americas Inc | 0 | $0 | 0.00% | −353,508−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −229,376−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −220,264−100.0% | Sold out |
| Stifel Financial Corp | 0 | $0 | 0.00% | −112,853−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −88,982−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −65,415−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −64,966−100.0% | Sold out |
| Arizona State Retirement System | 0 | $0 | 0.00% | −62,976−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −51,141−100.0% | Sold out |
| Great West Life Assurance Co | 0 | $0 | 0.00% | −46,013−100.0% | Sold out |
| Rpo LLC | 0 | $0 | 0.00% | −44,242−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −42,000−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −31,500−100.0% | Sold out |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −29,646−100.0% | Sold out |
| KLP Kapitalforvaltning AS | 0 | $0 | 0.00% | −26,200−100.0% | Sold out |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −15,034−100.0% | Sold out |
| Vermillion & White Wealth Management Group, LLC | 0 | $0 | 0.00% | −13,415−100.0% | Sold out |
| Pinnacle Wealth Management Advisory Group, LLC | 0 | $0 | 0.00% | −12,445−100.0% | Sold out |
| Estabrook Capital Management | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Nordwand Advisors, LLC | 0 | $0 | 0.00% | −4,000−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −3,040−100.0% | Sold out |
| Manchester Capital Management LLC | 0 | $0 | 0.00% | −2,380−100.0% | Sold out |
| Signaturefd, LLC | 0 | $0 | 0.00% | −388−100.0% | Sold out |
| Coppell Advisory Solutions LLC | 0 | $0 | 0.00% | −52−100.0% | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |