Karyopharm Therapeutics Inc.
KPTI- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 2 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.
13F holders, Q2 2024
Institutional positions in Karyopharm Therapeutics Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 114
- 0 vs. Q1 2024
- Shares held
- 67.6M
- −7.22M (−9.7%) vs. Q1 2024
- Total value
- $58.6M
- −$54.3M (−48.1%) vs. Q1 2024
- New holders
- 27
- 24 more added
- Sold out
- 27
- 33 more reduced
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KPTI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 96 | $206.8M |
| Q1 2026 | 77 | $98.4M |
| Q4 2025 | 68 | $69.6M |
| Q3 2025 | 52 | $19.5M |
| Q2 2025 | 50 | $19.0M |
| Q1 2025 | 50 | $13.7M |
| Q4 2024 | 87 | $41.2M |
| Q3 2024 | 91 | $49.2M |
| Q2 2024 | 114 | $58.6M |
| Q1 2024 | 114 | $113.0M |
| Q4 2023 | 120 | $63.5M |
| Q3 2023 | 120 | $102.8M |
| Q2 2023 | 138 | $145.0M |
| Q1 2023 | 132 | $340.1M |
| Q4 2022 | 155 | $334.4M |
| Q3 2022 | 147 | $364.1M |
| Q2 2022 | 150 | $302.8M |
| Q1 2022 | 139 | $501.8M |
| Q4 2021 | 143 | $347.5M |
| Q3 2021 | 134 | $334.4M |
| Q2 2021 | 154 | $608.7M |
| Q1 2021 | 171 | $637.1M |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Karyopharm Therapeutics Inc.; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wells Fargo & Company | 14 | $12 | 0.00% | −33,884−100.0% | Reduced |
| JJJ Advisors Inc. | 17 | $15 | 0.00% | 00.0% | Unchanged |
| CIBC Private Wealth Group, LLC | 50 | $40 | 0.00% | 00.0% | Unchanged |
| West Branch Capital LLC | 48 | $42 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 50 | $43 | 0.00% | −152−75.2% | Reduced |
| AdvisorNet Financial, Inc | 200 | $174 | 0.00% | 00.0% | Unchanged |
| Kelly Financial Services LLC | 250 | $217 | 0.00% | 00.0% | Unchanged |
| Providence Capital Advisors, LLC | 312 | $271 | 0.00% | 00.0% | Unchanged |
| Bruce G. Allen Investments, LLC | 507 | $440 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 500 | $445 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 538 | $467 | 0.00% | +538 | New |
| New York State Common Retirement Fund | 955 | $829 | 0.00% | −20,195−95.5% | Reduced |
| Activest Wealth Management | 1,000 | $868 | 0.00% | +1,000 | New |
| Harbour Investments, Inc. | 1,300 | $1.13K | 0.00% | 00.0% | Unchanged |
| MB, Levis & Associates, LLC | 1,500 | $1.30K | 0.00% | 00.0% | Unchanged |
| Founders Capital Management | 2,000 | $1.74K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 3,000 | $2.60K | 0.00% | 00.0% | Unchanged |
| Quent Capital, LLC | 3,489 | $3.03K | 0.00% | +3,489 | New |
| CWM, LLC | 6,248 | $5.00K | 0.00% | +6,236+51,966.7% | Added |
| Advisor Group Holdings, Inc. | 7,213 | $6.27K | 0.00% | −1,382−16.1% | Reduced |
| Janney Montgomery Scott LLC | 10,000 | $9.00K | 0.00% | 00.0% | Unchanged |
| Scientech Research LLC | 10,950 | $9.50K | 0.00% | +10,950 | New |
| Snowden Capital Advisors LLC | 11,000 | $9.54K | 0.00% | 00.0% | Unchanged |
| BLB&B Advisors, LLC | 11,150 | $9.67K | 0.00% | +11,150 | New |
| CI Private Wealth, LLC | 13,600 | $11.8K | 0.00% | −300−2.2% | Reduced |
| Two Sigma Investments, LP | 13,866 | $12.0K | 0.00% | +175+1.3% | Added |
| Victory Capital Management Inc | 13,993 | $12.1K | 0.00% | +13,993 | New |
| Winthrop Advisory Group LLC | 15,000 | $13.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 15,170 | $13.2K | 0.00% | −5,178−25.4% | Reduced |
| Paloma Partners Management Co | 15,435 | $13.4K | 0.00% | +15,435 | New |
| Rhumbline Advisers | 16,431 | $14.3K | 0.00% | −127,597−88.6% | Reduced |
| ELCO Management Co., LLC | 19,662 | $17.1K | 0.01% | −12,239−38.4% | Reduced |
| O'Shaughnessy Asset Management, LLC | 21,941 | $19.0K | 0.00% | +21,941 | New |
| Balyasny Asset Management LLC | 22,562 | $19.6K | 0.00% | +22,562 | New |
| Neuberger Berman Group LLC | 22,951 | $19.9K | 0.00% | +22,951 | New |
| Commonwealth Equity Services, LLC | 25,206 | $22.0K | 0.00% | −200−0.8% | Reduced |
| Banque Cantonale Vaudoise | 25,000 | $22.0K | 0.00% | 00.0% | Unchanged |
| Jump Financial, LLC | 26,798 | $23.3K | 0.00% | +26,798 | New |
| Catalyst Funds Management Pty Ltd | 28,600 | $24.8K | 0.01% | +28,600 | New |
| Engineers Gate Manager LP | 28,700 | $24.9K | 0.00% | 00.0% | Unchanged |
| Redwood Wealth Management Group, LLC | 34,030 | $29.5K | 0.02% | +34,030 | New |
| Kennedy Investment Group | 35,000 | $30.4K | 0.02% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 35,184 | $30.5K | 0.00% | +33,547+2,049.3% | Added |
| Point72 (DIFC) Ltd | 35,939 | $31.2K | 0.00% | +35,939 | New |
| Baird Financial Group, Inc. | 36,800 | $31.9K | 0.00% | +16,000+76.9% | Added |
| Eqis Capital Management, Inc. | 38,326 | $33.3K | 0.00% | +9,129+31.3% | Added |
| SEI Investments Co | 40,000 | $34.7K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 40,511 | $35.1K | 0.00% | +12,542+44.8% | Added |
| Simplicity Wealth,LLC | 49,160 | $42.7K | 0.00% | +5,149+11.7% | Added |
| Bleakley Financial Group, LLC | 49,160 | $42.7K | 0.00% | +5,149+11.7% | Added |
| Colony Group, LLC | 45,930 | $44.0K | 0.00% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 51,000 | $44.2K | 0.00% | −258,909−83.5% | Reduced |
| Royal Bank of Canada | 56,357 | $48.0K | 0.00% | −80,655−58.9% | Reduced |
| HSBC Holdings PLC | 53,091 | $48.1K | 0.00% | −472−0.9% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 56,945 | $49.4K | 0.00% | +56,945 | New |
| Schonfeld Strategic Advisors LLC | 57,600 | $50.0K | 0.00% | +57,600 | New |
| Verition Fund Management LLC | 68,932 | $59.8K | 0.00% | +68,932 | New |
| State of Wyoming | 82,685 | $71.7K | 0.01% | +35,378+74.8% | Added |
| Boothbay Fund Management, LLC | 91,091 | $79.0K | 0.00% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 97,100 | $84.0K | 0.00% | +2,009+2.1% | Added |
| Qube Research & Technologies Ltd | 106,470 | $92.4K | 0.00% | +106,470 | New |
| Woodline Partners LP | 134,112 | $116.4K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 140,576 | $122.0K | 0.01% | −102,265−42.1% | Reduced |
| UBS Group AG | 140,678 | $122.1K | 0.00% | −114,255−44.8% | Reduced |
| HRT Financial LP | 147,536 | $128.0K | 0.00% | +147,536 | New |
| Citigroup Inc | 162,027 | $140.6K | 0.00% | +143,103+756.2% | Added |
| Exchange Traded Concepts, LLC | 162,178 | $140.7K | 0.00% | −50,460−23.7% | Reduced |
| Point72 Asia (Singapore) Pte. Ltd. | 165,318 | $143.4K | 0.03% | +165,318 | New |
| Bank of New York Mellon Corp | 166,315 | $144.3K | 0.00% | −320,745−65.9% | Reduced |
| Acadian Asset Management LLC | 194,168 | $167.0K | 0.00% | +194,168 | New |
| DAFNA Capital Management LLC | 192,678 | $167.2K | 0.04% | 00.0% | Unchanged |
| Morgan Stanley | 200,008 | $173.5K | 0.00% | −94,779−32.2% | Reduced |
| Centiva Capital, LP | 203,600 | $176.6K | 0.01% | +203,600 | New |
| Atom Investors LP | 261,847 | $227.2K | 0.02% | +17,450+7.1% | Added |
| Bridgeway Capital Management, LLC | 264,500 | $229.5K | 0.01% | +75,000+39.6% | Added |
| FMR LLC | 293,213 | $254.4K | 0.00% | +19,405+7.1% | Added |
| Bank of America Corp | 298,685 | $259.0K | 0.00% | +140,770+89.1% | Added |
| Los Angeles Capital Management LLC | 354,020 | $307.1K | 0.00% | −33,500−8.6% | Reduced |
| Ikarian Capital, LLC | 409,355 | $355.2K | 0.11% | 00.0% | Unchanged |
| Y-Intercept (Hong Kong) Ltd | 410,954 | $356.5K | 0.02% | +410,954 | New |
| Susquehanna International Group, LLP | 443,474 | $384.8K | 0.00% | +366,875+479.0% | Added |
| State Street Corp | 453,810 | $393.7K | 0.00% | −1,831,978−80.1% | Reduced |
| Birchview Capital, LP | 469,832 | $407.6K | 0.38% | 00.0% | Unchanged |
| Macquarie Group Ltd | 505,684 | $438.9K | 0.00% | +5,684+1.1% | Added |
| Superstring Capital Management LP | 534,485 | $463.7K | 0.58% | +534,485 | New |
| Silverarc Capital Management, LLC | 558,466 | $484.5K | 0.12% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 568,975 | $493.6K | 0.01% | +568,975 | New |
| Altium Capital Management LP | 740,000 | $642.0K | 0.27% | 00.0% | Unchanged |
| AQR Capital Management LLC | 748,020 | $649.0K | 0.00% | +622,194+494.5% | Added |
| Renaissance Technologies LLC | 756,227 | $656.1K | 0.00% | −150,573−16.6% | Reduced |
| D. E. Shaw & Co., Inc. | 844,112 | $732.4K | 0.00% | −118,713−12.3% | Reduced |
| Northern Trust Corp | 870,167 | $755.0K | 0.00% | −88,638−9.2% | Reduced |
| Barclays PLC | 873,274 | $757.7K | 0.00% | −19,541−2.2% | Reduced |
| Gsa Capital Partners LLP | 983,417 | $853.0K | 0.06% | −315,734−24.3% | Reduced |
| UBS Oconnor LLC | 1,102,391 | $956.9K | 0.03% | +380,064+52.6% | Added |
| AlphaCentric Advisors LLC | 1,125,000 | $976.0K | 0.72% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 1,196,792 | $1.04M | 0.02% | +1,196,792 | New |
| Deutsche Bank AG | 1,268,777 | $1.10M | 0.00% | −56,200−4.2% | Reduced |
| JPMorgan Chase & Co | 1,275,859 | $1.11M | 0.00% | −101,725−7.4% | Reduced |
| Geode Capital Management, LLC | 1,311,536 | $1.14M | 0.00% | −1,208,569−48.0% | Reduced |