Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 354
- +1 vs. Q2 2024
- Shares held
- 157.5M
- +24.6M (+18.5%) vs. Q2 2024
- Total value
- $6.31B
- −$23.0M (−0.4%) vs. Q2 2024
- New holders
- 53
- 131 more added
- Sold out
- 52
- 107 more reduced
4 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Schonfeld Strategic Advisors LLC | 362,888 | $14.5M | 0.12% | −360,730−49.9% | Reduced |
| Voloridge Investment Management, LLC | 380,641 | $15.2M | 0.06% | +380,641 | New |
| Ameriprise Financial Inc | 397,898 | $15.9M | 0.00% | +389,106+4,425.7% | Added |
| Ghisallo Capital Management LLC | 400,000 | $16.0M | 0.79% | +400,000 | New |
| Citadel Advisors LLC | 401,151 | $16.1M | 0.02% | −225,882−36.0% | Reduced |
| First Trust Advisors LP | 402,300 | $16.1M | 0.02% | +386,106+2,384.3% | Added |
| Tocqueville Asset Management L.P. | 406,870 | $16.3M | 0.26% | +181,800+80.8% | Added |
| Millennium Management LLC | 430,723 | $17.3M | 0.01% | +302,508+235.9% | Added |
| Nomura Holdings Inc | 453,069 | $18.1M | 0.14% | −48,119−9.6% | Reduced |
| Eversept Partners, LP | 471,355 | $18.9M | 1.45% | +14,474+3.2% | Added |
| Adage Capital Partners GP, L.L.C. | 500,000 | $20.0M | 0.04% | −300,000−37.5% | Reduced |
| EcoR1 Capital, LLC | 500,000 | $20.0M | 0.69% | +500,000 | New |
| AXA S.A. | 561,243 | $22.5M | 0.07% | +96,280+20.7% | Added |
| Bank of America Corp | 568,660 | $22.8M | 0.00% | +54,117+10.5% | Added |
| JPMorgan Chase & Co | 568,906 | $22.8M | 0.00% | −25,185−4.2% | Reduced |
| Pinnacle Associates Ltd | 458,979 | $23.2M | 0.40% | +5,600+1.2% | Added |
| Man Group plc | 596,263 | $23.9M | 0.07% | −37,146−5.9% | Reduced |
| J. Goldman & Co LP | 609,416 | $24.4M | 1.06% | +591,914+3,382.0% | Added |
| Bank of New York Mellon Corp | 610,893 | $24.5M | 0.00% | +13,414+2.2% | Added |
| Barclays PLC | 637,032 | $25.5M | 0.01% | +21,358+3.5% | Added |
| Jacobs Levy Equity Management, Inc | 650,779 | $26.1M | 0.10% | +77,909+13.6% | Added |
| Royal Bank of Canada | 670,149 | $26.8M | 0.01% | −8,211−1.2% | Reduced |
| Northern Trust Corp | 742,904 | $29.8M | 0.00% | +24,929+3.5% | Added |
| Logos Global Management LP | 750,000 | $30.0M | 3.37% | +450,000+150.0% | Added |
| Hudson Bay Capital Management LP | 766,900 | $30.7M | 0.21% | +400,900+109.5% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 779,721 | $31.2M | 0.08% | −1,032−0.1% | Reduced |
| Invesco Ltd. | 810,301 | $32.5M | 0.01% | −158,616−16.4% | Reduced |
| Two Sigma Investments, LP | 919,077 | $36.8M | 0.08% | −109,065−10.6% | Reduced |
| Candriam Luxembourg S.C.A. | 948,266 | $38.0M | 0.22% | 00.0% | Unchanged |
| TD Asset Management Inc | 1,092,990 | $44.6M | 0.04% | +140,228+14.7% | Added |
| Morgan Stanley | 1,310,451 | $52.5M | 0.00% | +297,646+29.4% | Added |
| Pictet Asset Management Holding SA | 1,303,501 | $52.7M | 0.06% | −1,106,453−45.9% | Reduced |
| Two Sigma Advisers, LP | 1,332,411 | $53.4M | 0.13% | +45,300+3.5% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,384,269 | $55.5M | 0.51% | +23,244+1.7% | Added |
| Charles Schwab Investment Management Inc | 1,443,020 | $57.8M | 0.01% | +114,914+8.7% | Added |
| BVF Inc | 1,451,879 | $58.2M | 1.70% | −1,734,497−54.4% | Reduced |
| Clearbridge Investments, LLC | 1,702,393 | $68.2M | 0.05% | −457,877−21.2% | Reduced |
| Macquarie Group Ltd | 1,869,806 | $74.9M | 0.08% | −3,862−0.2% | Reduced |
| Marshall Wace, LLP | 1,920,464 | $76.9M | 0.10% | +1,747,265+1,008.8% | Added |
| Norges Bank | 2,027,161 | $81.2M | 0.01% | +1,007,820+98.9% | Added |
| Deep Track Capital, LP | 2,200,000 | $88.1M | 2.81% | +200,000+10.0% | Added |
| Artisan Partners Limited Partnership | 2,240,455 | $89.8M | 0.13% | +569,419+34.1% | Added |
| OrbiMed Advisors LLC | 2,324,447 | $93.1M | 1.70% | −47,886−2.0% | Reduced |
| Geode Capital Management, LLC | 2,668,358 | $106.9M | 0.01% | +183,814+7.4% | Added |
| Tweedy, Browne Co LLC | 3,454,676 | $138.4M | 6.60% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 4,210,172 | $168.7M | 0.02% | +275,861+7.0% | Added |
| State Street Corp | 4,850,137 | $194.3M | 0.01% | +659,632+15.7% | Added |
| Capital World Investors | 7,828,372 | $313.6M | 0.05% | +5,576,283+247.6% | Added |
| Bellevue Group AG | 7,874,400 | $315.4M | 5.11% | −386,034−4.7% | Reduced |
| Wellington Management Group LLP | 8,735,787 | $350.0M | 0.06% | +2,166,979+33.0% | Added |
| BlackRock, Inc. | 10,813,023 | $433.2M | 0.01% | +10,813,023 | New |
| T. Rowe Price Investment Management, Inc. | 14,168,116 | $567.6M | 0.34% | +1,528,432+12.1% | Added |
| Vanguard Group Inc | 15,055,758 | $603.1M | 0.01% | +1,210,046+8.7% | Added |
| FMR LLC | 22,479,529 | $900.5M | 0.05% | +584,723+2.7% | Added |
| Proequities, Inc. | 0 | $0 | 0.00% | −26−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −1,077,321−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −250,000−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −209,194−100.0% | Sold out |
| Zimmer Partners, LP | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Parkman Healthcare Partners LLC | 0 | $0 | 0.00% | −161,705−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −159,685−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −137,210−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −120,814−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −93,000−100.0% | Sold out |
| Bank of Nova Scotia | 0 | $0 | 0.00% | −51,879−100.0% | Sold out |
| DRW Securities, LLC | 0 | $0 | 0.00% | −50,956−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −35,311−100.0% | Sold out |
| Inceptionr LLC | 0 | $0 | 0.00% | −17,289−100.0% | Sold out |
| Simplicity Wealth,LLC | 0 | $0 | 0.00% | −16,340−100.0% | Sold out |
| Parallax Volatility Advisers, L.P. | 0 | $0 | 0.00% | −12,310−100.0% | Sold out |
| Lisanti Capital Growth, LLC | 0 | $0 | 0.00% | −10,845−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −8,231−100.0% | Sold out |
| Pearl River Capital, LLC | 0 | $0 | 0.00% | −6,187−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −6,184−100.0% | Sold out |
| Oppenheimer Asset Management Inc. | 0 | $0 | 0.00% | −5,777−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −5,600−100.0% | Sold out |
| Perkins Capital Management Inc | 0 | $0 | 0.00% | −5,550−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −5,421−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −5,326−100.0% | Sold out |
| Stephens Inc | 0 | $0 | 0.00% | −5,138−100.0% | Sold out |
| Beaird Harris Wealth Management, LLC | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −5,491−100.0% | Sold out |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −4,800−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −4,694−100.0% | Sold out |
| Mitchell & Pahl Private Wealth, LLC | 0 | $0 | 0.00% | −4,540−100.0% | Sold out |
| Wealth Enhancement Advisory Services, LLC | 0 | $0 | 0.00% | −4,508−100.0% | Sold out |
| Prospera Financial Services Inc | 0 | $0 | 0.00% | −4,451−100.0% | Sold out |
| Checchi Capital Advisers, LLC | 0 | $0 | 0.00% | −4,234−100.0% | Sold out |
| Redwood Wealth Management Group, LLC | 0 | $0 | 0.00% | −2,408−100.0% | Sold out |
| Pacer Advisors, Inc. | 0 | $0 | 0.00% | −960−100.0% | Sold out |
| nVerses Capital, LLC | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Pingora Partners LLC | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Banque Cantonale Vaudoise | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| ORG Partners LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −163−100.0% | Sold out |
| Ashton Thomas Private Wealth, LLC | 0 | $0 | 0.00% | −150−100.0% | Sold out |
| Unique Wealth Strategies, LLC | 0 | $0 | 0.00% | −140−100.0% | Sold out |
| Family Firm, Inc. | 0 | $0 | 0.00% | −91−100.0% | Sold out |
| Orion Capital Management LLC | 0 | $0 | 0.00% | −80−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −80−100.0% | Sold out |