Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 361
- −2 vs. Q4 2023
- Shares held
- 142.2M
- −349.1K (−0.2%) vs. Q4 2023
- Total value
- $6.17B
- −$1.04B (−14.4%) vs. Q4 2023
- New holders
- 49
- 124 more added
- Sold out
- 51
- 127 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Kennedy Capital Management, Inc. | 249,527 | $10.8M | 0.22% | +21,102+9.2% | Added |
| Man Group plc | 253,221 | $11.0M | 0.03% | +174,746+222.7% | Added |
| Swiss National Bank | 254,900 | $11.0M | 0.01% | +600+0.2% | Added |
| CI Private Wealth, LLC | 267,291 | $11.6M | 0.02% | −210.0% | Reduced |
| Zimmer Partners, LP | 270,300 | $11.7M | 0.25% | +270,300 | New |
| Assenagon Asset Management S.A. | 271,263 | $11.8M | 0.03% | +86,862+47.1% | Added |
| Cubist Systematic Strategies, LLC | 277,791 | $12.0M | 0.14% | +78,314+39.3% | Added |
| Verition Fund Management LLC | 285,947 | $12.4M | 0.12% | +143,093+100.2% | Added |
| Point72 Asset Management, L.P. | 286,602 | $12.4M | 0.04% | −682,198−70.4% | Reduced |
| Liontrust Investment Partners LLP | 288,544 | $12.5M | 0.17% | +4,563+1.6% | Added |
| Cutter Capital Management, LP | 289,366 | $12.5M | 4.84% | +289,366 | New |
| Baillie Gifford & Co | 295,683 | $12.8M | 0.01% | −2,800−0.9% | Reduced |
| C WorldWide Group Holding A/S | 300,000 | $13.0M | 0.15% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 335,500 | $14.5M | 0.13% | +190,500+131.4% | Added |
| Eversept Partners, LP | 376,438 | $16.3M | 1.22% | +51,784+16.0% | Added |
| Groupama Asset Managment | 257,868 | $17.0M | 0.31% | −99,168−27.8% | Reduced |
| Artisan Partners Limited Partnership | 416,729 | $18.1M | 0.03% | +416,729 | New |
| First Turn Management, LLC | 421,487 | $18.3M | 2.73% | +64,808+18.2% | Added |
| Nuveen Asset Management, LLC | 423,030 | $18.3M | 0.01% | +99,024+30.6% | Added |
| Invesco Ltd. | 442,887 | $19.2M | 0.00% | +236,986+115.1% | Added |
| Pinnacle Associates Ltd | 459,758 | $19.9M | 0.31% | +779+0.2% | Added |
| AXA S.A. | 464,815 | $20.1M | 0.06% | +740.0% | Added |
| Nomura Holdings Inc | 470,837 | $20.4M | 0.17% | −18,352−3.8% | Reduced |
| Jacobs Levy Equity Management, Inc | 571,763 | $24.8M | 0.11% | +62,230+12.2% | Added |
| Barclays PLC | 577,387 | $25.0M | 0.01% | −67,121−10.4% | Reduced |
| Millennium Management LLC | 583,179 | $25.3M | 0.02% | −307,146−34.5% | Reduced |
| Bank of New York Mellon Corp | 583,589 | $25.3M | 0.00% | −57,474−9.0% | Reduced |
| Wells Fargo & Company | 584,158 | $25.3M | 0.01% | −10,092−1.7% | Reduced |
| Bank of America Corp | 606,298 | $26.3M | 0.00% | +151,220+33.2% | Added |
| JPMorgan Chase & Co | 630,979 | $27.4M | 0.00% | −310,053−32.9% | Reduced |
| Northern Trust Corp | 692,247 | $30.0M | 0.01% | +4,261+0.6% | Added |
| Royal Bank of Canada | 732,237 | $31.7M | 0.01% | −42,009−5.4% | Reduced |
| Farallon Capital Management, L.L.C. | 734,000 | $31.8M | 0.19% | −821,020−52.8% | Reduced |
| Squarepoint Ops LLC | 745,173 | $32.3M | 0.13% | +685,969+1,158.7% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 778,593 | $33.8M | 0.09% | +438,926+129.2% | Added |
| Capital World Investors | 839,463 | $36.4M | 0.01% | 00.0% | Unchanged |
| TD Asset Management Inc | 898,362 | $38.9M | 0.04% | −58,490−6.1% | Reduced |
| Candriam Luxembourg S.C.A. | 911,897 | $39.5M | 0.25% | +282,830+45.0% | Added |
| Adage Capital Partners GP, L.L.C. | 1,000,000 | $43.4M | 0.08% | −385,300−27.8% | Reduced |
| Two Sigma Advisers, LP | 1,040,111 | $45.1M | 0.10% | +263,100+33.9% | Added |
| Two Sigma Investments, LP | 1,083,879 | $47.0M | 0.12% | +282,431+35.2% | Added |
| Morgan Stanley | 1,163,598 | $50.4M | 0.00% | +73,335+6.7% | Added |
| Norges Bank | 1,236,998 | $53.6M | 0.01% | +65,062+5.6% | Added |
| Charles Schwab Investment Management Inc | 1,301,368 | $56.4M | 0.01% | +26,049+2.0% | Added |
| Deep Track Capital, LP | 1,373,475 | $59.5M | 1.71% | +124,407+10.0% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,399,852 | $60.7M | 0.42% | −505,204−26.5% | Reduced |
| OrbiMed Advisors LLC | 2,013,033 | $87.3M | 1.71% | −51,764−2.5% | Reduced |
| Geode Capital Management, LLC | 2,364,256 | $102.5M | 0.01% | +88,325+3.9% | Added |
| BVF Inc | 2,428,613 | $105.3M | 2.89% | 00.0% | Unchanged |
| Macquarie Group Ltd | 3,200,578 | $138.7M | 0.16% | +112,343+3.6% | Added |
| Tweedy, Browne Co LLC | 3,454,676 | $149.8M | 7.03% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 3,522,203 | $152.7M | 0.02% | −732,871−17.2% | Reduced |
| Pictet Asset Management Holding SA | 3,739,757 | $163.2M | 0.18% | +221,440+6.3% | Added |
| State Street Corp | 4,155,664 | $180.1M | 0.01% | +146,867+3.7% | Added |
| Clearbridge Investments, LLC | 4,466,191 | $193.6M | 0.15% | −241,289−5.1% | Reduced |
| Wellington Management Group LLP | 5,695,699 | $246.9M | 0.04% | +1,078,721+23.4% | Added |
| Bellevue Group AG | 8,299,514 | $359.8M | 5.49% | −414,473−4.8% | Reduced |
| BlackRock Inc. | 9,771,891 | $423.6M | 0.01% | +714,361+7.9% | Added |
| T. Rowe Price Investment Management, Inc. | 13,317,112 | $577.3M | 0.35% | +115,659+0.9% | Added |
| Vanguard Group Inc | 13,430,456 | $582.2M | 0.01% | −773,025−5.4% | Reduced |
| FMR LLC | 21,862,735 | $947.7M | 0.06% | +341,863+1.6% | Added |
| Camber Capital Management LP | 0 | $0 | 0.00% | −865,000−100.0% | Sold out |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | $0 | 0.00% | −127,954−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −73,256−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −57,348−100.0% | Sold out |
| Cowen and Company, LLC | 0 | $0 | 0.00% | −51,415−100.0% | Sold out |
| Estate Counselors, LLC | 0 | $0 | 0.00% | −32,800−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −24,054−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −20,015−100.0% | Sold out |
| Calamos Advisors LLC | 0 | $0 | 0.00% | −16,379−100.0% | Sold out |
| Friedenthal Financial | 0 | $0 | 0.00% | −14,225−100.0% | Sold out |
| Granite Bay Wealth Management, LLC | 0 | $0 | 0.00% | −13,579−100.0% | Sold out |
| Captrust Financial Advisors | 0 | $0 | 0.00% | −10,108−100.0% | Sold out |
| Point72 Middle East FZE | 0 | $0 | 0.00% | −9,983−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −9,271−100.0% | Sold out |
| Weiss Asset Management LP | 0 | $0 | 0.00% | −5,874−100.0% | Sold out |
| Kapitalo Investimentos Ltda | 0 | $0 | 0.00% | −5,714−100.0% | Sold out |
| Legato Capital Management LLC | 0 | $0 | 0.00% | −5,455−100.0% | Sold out |
| Capital Wealth Planning, LLC | 0 | $0 | 0.00% | −5,408−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −5,273−100.0% | Sold out |
| Oracle Alpha Inc. | 0 | $0 | 0.00% | −5,019−100.0% | Sold out |
| Mercer Global Advisors Inc | 0 | $0 | 0.00% | −4,676−100.0% | Sold out |
| Mitchell & Pahl Private Wealth, LLC | 0 | $0 | 0.00% | −4,617−100.0% | Sold out |
| Koss-Olinger Consulting, LLC | 0 | $0 | 0.00% | −4,539−100.0% | Sold out |
| MML Investors Services, LLC | 0 | $0 | 0.00% | −4,324−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −4,269−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −4,300−100.0% | Sold out |
| Checchi Capital Advisers, LLC | 0 | $0 | 0.00% | −4,234−100.0% | Sold out |
| Berkshire Asset Management LLC | 0 | $0 | 0.00% | −4,180−100.0% | Sold out |
| Cetera Advisor Networks LLC | 0 | $0 | 0.00% | −4,081−100.0% | Sold out |
| CIBC Asset Management Inc | 0 | $0 | 0.00% | −4,002−100.0% | Sold out |
| Itau Unibanco Holding S.A. | 0 | $0 | 0.00% | −1,429−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −1,018−100.0% | Sold out |
| nVerses Capital, LLC | 0 | $0 | 0.00% | – | Sold out |
| Glassman Wealth Services | 0 | $0 | 0.00% | −686−100.0% | Sold out |
| Tennessee Valley Asset Management Partners | 0 | $0 | 0.00% | −673−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −519−100.0% | Sold out |
| ORG Partners LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Colonial Trust Co | 0 | $0 | 0.00% | −120−100.0% | Sold out |