Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 361
- −2 vs. Q4 2023
- Shares held
- 142.2M
- −349.1K (−0.2%) vs. Q4 2023
- Total value
- $6.17B
- −$1.04B (−14.4%) vs. Q4 2023
- New holders
- 49
- 124 more added
- Sold out
- 51
- 127 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Paloma Partners Management Co | 4,909 | $212.8K | 0.03% | +4,909 | New |
| Brevan Howard Capital Management LP | 4,924 | $213.5K | 0.02% | +4,924 | New |
| Beaird Harris Wealth Management, LLC | 5,000 | $216.8K | 0.02% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 5,085 | $221.0K | 0.00% | −6,001−54.1% | Reduced |
| Level Four Advisory Services, LLC | 4,396 | $222.4K | 0.01% | +94+2.2% | Added |
| Buckingham Strategic Wealth, LLC | 5,251 | $227.6K | 0.00% | +81+1.6% | Added |
| Handelsinvest Investeringsforvaltning | 5,287 | $229.0K | 0.11% | −2,746−34.2% | Reduced |
| Kestra Advisory Services, LLC | 5,550 | $240.6K | 0.00% | +510+10.1% | Added |
| Perkins Capital Management Inc | 5,550 | $241.0K | 0.20% | 00.0% | Unchanged |
| Massachusetts Financial Services Co | 5,580 | $241.9K | 0.00% | −12−0.2% | Reduced |
| M&T Bank Corp | 5,848 | $253.7K | 0.00% | +660+12.7% | Added |
| Acadian Asset Management LLC | 5,891 | $255.0K | 0.00% | +5,891 | New |
| Diversified Trust Co | 6,015 | $260.8K | 0.01% | +6,015 | New |
| Wrapmanager Inc | 6,668 | $289.1K | 0.08% | −736−9.9% | Reduced |
| Baird Financial Group, Inc. | 6,696 | $290.3K | 0.00% | +7+0.1% | Added |
| Regions Financial Corp | 6,785 | $294.1K | 0.00% | +2,700+66.1% | Added |
| Gotham Asset Management, LLC | 6,786 | $294.2K | 0.00% | −203−2.9% | Reduced |
| Castle Rock Wealth Management, LLC | 6,972 | $299.9K | 0.08% | 00.0% | Unchanged |
| Point72 Asia (Singapore) Pte. Ltd. | 6,986 | $302.8K | 0.08% | +6,986 | New |
| JustInvest LLC | 7,363 | $319.2K | 0.01% | −979−11.7% | Reduced |
| Vontobel Holding Ltd. | 7,497 | $325.0K | 0.00% | −713−8.7% | Reduced |
| Twin Tree Management, LP | 7,563 | $327.9K | 0.01% | +7,563 | New |
| SG Americas Securities, LLC | 7,582 | $329.0K | 0.00% | +1,453+23.7% | Added |
| Virtus ETF Advisers LLC | 7,648 | $331.5K | 0.18% | +1,100+16.8% | Added |
| International Assets Investment Management, LLC | 7,607 | $334.3K | 0.03% | +7,607 | New |
| Lazard Asset Management LLC | 7,855 | $339.0K | 0.00% | +1,214+18.3% | Added |
| MetLife Investment Management | 7,841 | $339.9K | 0.00% | +24+0.3% | Added |
| Stephens Inc | 7,853 | $340.4K | 0.01% | −102−1.3% | Reduced |
| Utah Retirement Systems | 7,900 | $342.5K | 0.00% | 00.0% | Unchanged |
| Torno Capital, LLC | 8,000 | $346.8K | 0.07% | +5,500+220.0% | Added |
| Gsa Capital Partners LLP | 8,325 | $361.0K | 0.03% | −3,355−28.7% | Reduced |
| Centiva Capital, LP | 8,474 | $367.3K | 0.02% | +8,474 | New |
| Simplex Trading, LLC | 8,530 | $369.0K | 0.01% | −1,015−10.6% | Reduced |
| XTX Topco Ltd | 8,585 | $372.2K | 0.05% | +8,585 | New |
| Deutsche Bank AG | 8,588 | $372.3K | 0.00% | −27,114−75.9% | Reduced |
| The PNC Financial Services Group, Inc. | 8,819 | $382.3K | 0.00% | +441+5.3% | Added |
| Amalgamated Bank | 9,203 | $399.0K | 0.00% | −19,792−68.3% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 9,312 | $404.0K | 0.00% | −1,722−15.6% | Reduced |
| Walleye Trading LLC | 9,362 | $405.8K | 0.01% | +9,214+6,225.7% | Added |
| Truist Financial Corp | 9,499 | $411.8K | 0.00% | −466−4.7% | Reduced |
| Fifth Third Bancorp | 9,633 | $417.6K | 0.00% | +351+3.8% | Added |
| Midwest Professional Planners, LTD. | 9,716 | $421.2K | 0.15% | +1,197+14.1% | Added |
| Franklin Resources Inc | 9,809 | $425.2K | 0.00% | −3,896−28.4% | Reduced |
| E Fund Management Co., Ltd. | 9,825 | $425.9K | 0.03% | −40−0.4% | Reduced |
| Oppenheimer Asset Management Inc. | 9,826 | $426.0K | 0.01% | −723−6.9% | Reduced |
| Bard Financial Services, Inc. | 9,950 | $431.3K | 0.05% | −4,150−29.4% | Reduced |
| Cypress Capital, LLC | 10,000 | $433.5K | 0.12% | +10,000 | New |
| Sectoral Asset Management Inc | 10,100 | $437.8K | 0.17% | +3,620+55.9% | Added |
| Sherbrooke Park Advisers LLC | 10,119 | $438.7K | 0.09% | +3,330+49.0% | Added |
| ProShare Advisors LLC | 10,216 | $442.9K | 0.00% | +1,049+11.4% | Added |
| Capula Management Ltd | 10,217 | $442.9K | 0.01% | +10,217 | New |
| Maryland State Retirement & Pension System | 10,950 | $451.5K | 0.01% | 00.0% | Unchanged |
| Corton Capital Inc. | 10,631 | $460.9K | 0.17% | −845−7.4% | Reduced |
| Suvretta Capital Management, LLC | 10,800 | $468.2K | 0.02% | +10,800 | New |
| PEAK6 Investments LLC | 11,000 | $476.9K | 0.02% | +1,999+22.2% | Added |
| Two Sigma Securities, LLC | 11,122 | $482.1K | 0.02% | −4,282−27.8% | Reduced |
| Brown Advisory Inc | 11,122 | $482.1K | 0.00% | −422−3.7% | Reduced |
| Northwestern Mutual Wealth Management Co | 11,146 | $483.2K | 0.00% | 00.0% | Unchanged |
| Plancorp, LLC | 11,155 | $483.6K | 0.02% | 00.0% | Unchanged |
| Aquatic Capital Management LLC | 11,700 | $507.2K | 0.02% | +5,300+82.8% | Added |
| Chartwell Investment Partners, LLC | 11,756 | $510.0K | 0.02% | −1,226−9.4% | Reduced |
| US Bancorp | 11,927 | $517.0K | 0.00% | −8−0.1% | Reduced |
| Wolverine Trading, LLC | 12,047 | $522.2K | 0.01% | +2,552+26.9% | Added |
| Horizon Kinetics Asset Management LLC | 12,476 | $540.8K | 0.01% | 00.0% | Unchanged |
| Bank Julius Baer & Co. Ltd, Zurich | 14,230 | $570.6K | 0.00% | −4,820−25.3% | Reduced |
| Martingale Asset Management L P | 13,315 | $577.2K | 0.01% | +30.0% | Added |
| American Century Companies Inc | 13,378 | $579.9K | 0.00% | +162+1.2% | Added |
| Raymond James Financial Services Advisors, Inc. | 13,508 | $585.6K | 0.00% | −139−1.0% | Reduced |
| North Star Asset Management Inc | 13,640 | $591.3K | 0.03% | −10−0.1% | Reduced |
| Westmount Partners, LLC | 13,872 | $601.4K | 0.22% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 15,081 | $613.4K | 0.00% | +15,081 | New |
| Neuberger Berman Group LLC | 14,234 | $617.0K | 0.00% | +236+1.7% | Added |
| Entropy Technologies, LP | 14,542 | $630.4K | 0.07% | +14,542 | New |
| Tanaka Capital Management Inc | 14,612 | $633.0K | 1.56% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 14,626 | $633.9K | 0.00% | −4,284−22.7% | Reduced |
| Marshall Wace, LLP | 15,443 | $669.5K | 0.00% | −118,106−88.4% | Reduced |
| Ameriprise Financial Inc | 15,673 | $679.4K | 0.00% | −9,952−38.8% | Reduced |
| Jump Financial, LLC | 15,693 | $680.3K | 0.02% | −46,046−74.6% | Reduced |
| Xponance, Inc. | 16,209 | $702.7K | 0.01% | −484−2.9% | Reduced |
| Bleakley Financial Group, LLC | 16,229 | $703.5K | 0.02% | +3,990+32.6% | Added |
| Simplicity Wealth,LLC | 16,229 | $703.5K | 0.02% | +16,229 | New |
| Public Employees Retirement Association of Colorado | 16,574 | $718.0K | 0.00% | 00.0% | Unchanged |
| Aigen Investment Management, LP | 16,747 | $726.0K | 0.16% | −56,973−77.3% | Reduced |
| NBT Bank N A | 17,050 | $739.1K | 0.05% | 00.0% | Unchanged |
| Victory Capital Management Inc | 17,637 | $764.6K | 0.00% | −10,156−36.5% | Reduced |
| Edgestream Partners, L.P. | 17,646 | $765.0K | 0.04% | +17,646 | New |
| Toroso Investments, LLC | 20,405 | $884.6K | 0.02% | +20,405 | New |
| Nicollet Investment Management, Inc. | 20,521 | $890.0K | 0.33% | +10,745+109.9% | Added |
| Mariner, LLC | 20,784 | $901.0K | 0.00% | +112+0.5% | Added |
| Pathstone Holdings, LLC | 21,253 | $921.3K | 0.00% | +9,371+78.9% | Added |
| Cetera Investment Advisers | 21,758 | $943.2K | 0.00% | +21,758 | New |
| Commonwealth Equity Services, LLC | 21,974 | $953.0K | 0.00% | +512+2.4% | Added |
| Natixis Advisors, L.P. | 23,028 | $998.0K | 0.00% | +5,715+33.0% | Added |
| Teachers Retirement System of the State of Kentucky | 24,083 | $1.04M | 0.01% | +9,965+70.6% | Added |
| Pearl River Capital, LLC | 25,959 | $1.13M | 0.18% | +25,959 | New |
| Janney Montgomery Scott LLC | 26,893 | $1.17M | 0.00% | −1,486−5.2% | Reduced |
| Creative Planning | 27,005 | $1.17M | 0.00% | +1,706+6.7% | Added |
| Lisanti Capital Growth, LLC | 27,835 | $1.21M | 0.29% | −34,580−55.4% | Reduced |
| Blair William & Co | 27,838 | $1.21M | 0.00% | +11,210+67.4% | Added |
| China Universal Asset Management Co., Ltd. | 28,027 | $1.21M | 0.15% | +11,429+68.9% | Added |