Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 365
- +57 vs. Q3 2023
- Shares held
- 142.5M
- +2.89M (+2.1%) vs. Q3 2023
- Total value
- $7.21B
- +$870.9M (+13.7%) vs. Q3 2023
- New holders
- 85
- 108 more added
- Sold out
- 28
- 116 more reduced
4 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Privium Fund Management B.V. | 217,493 | $11.5M | 3.20% | −11,000−4.8% | Reduced |
| Kennedy Capital Management, Inc. | 228,425 | $11.6M | 0.25% | −10,210−4.3% | Reduced |
| Stifel Financial Corp | 246,029 | $12.4M | 0.02% | −174−0.1% | Reduced |
| Nikko Asset Management Americas, Inc. | 252,459 | $12.8M | 0.12% | −40,014−13.7% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 252,459 | $12.8M | 0.01% | −40,014−13.7% | Reduced |
| Citadel Advisors LLC | 252,528 | $12.8M | 0.01% | −283,390−52.9% | Reduced |
| Swiss National Bank | 254,300 | $12.9M | 0.01% | −28,800−10.2% | Reduced |
| Alliancebernstein L.P. | 257,320 | $13.0M | 0.01% | −47,198−15.5% | Reduced |
| Manufacturers Life Insurance Company, The | 260,702 | $13.2M | 0.01% | +31,025+13.5% | Added |
| Voloridge Investment Management, LLC | 264,121 | $13.4M | 0.05% | +264,121 | New |
| CI Private Wealth, LLC | 267,312 | $13.5M | 0.02% | −39,678−12.9% | Reduced |
| Liontrust Investment Partners LLP | 283,981 | $14.4M | 0.21% | −26,045−8.4% | Reduced |
| Amundi | 272,650 | $14.4M | 0.01% | +146,986+117.0% | Added |
| Baillie Gifford & Co | 298,483 | $15.1M | 0.01% | −18,146−5.7% | Reduced |
| C WorldWide Group Holding A/S | 300,000 | $15.2M | 0.20% | +300,000 | New |
| Schonfeld Strategic Advisors LLC | 313,274 | $15.8M | 0.13% | +251,726+409.0% | Added |
| Nuveen Asset Management, LLC | 324,006 | $16.4M | 0.01% | +14,862+4.8% | Added |
| Eversept Partners, LP | 324,654 | $16.4M | 1.61% | +72,208+28.6% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 339,667 | $17.2M | 0.05% | +339,667 | New |
| BNP Paribas Arbitrage, SA | 354,955 | $18.0M | 0.03% | −55,719−13.6% | Reduced |
| First Turn Management, LLC | 356,679 | $18.0M | 2.59% | +356,679 | New |
| Groupama Asset Managment | 357,036 | $18.1M | 0.47% | +357,036 | New |
| Goldman Sachs Group Inc | 381,382 | $19.3M | 0.00% | +43,555+12.9% | Added |
| Bank of America Corp | 455,078 | $23.0M | 0.00% | −80,966−15.1% | Reduced |
| Pinnacle Associates Ltd | 458,979 | $23.2M | 0.39% | −4,056−0.9% | Reduced |
| AXA S.A. | 464,741 | $23.5M | 0.08% | −16,841−3.5% | Reduced |
| Nomura Holdings Inc | 489,189 | $24.7M | 0.22% | +29,878+6.5% | Added |
| Jacobs Levy Equity Management, Inc | 509,533 | $25.8M | 0.13% | +136,416+36.6% | Added |
| Wells Fargo & Company | 594,250 | $30.1M | 0.01% | −23,680−3.8% | Reduced |
| Candriam Luxembourg S.C.A. | 629,067 | $31.8M | 0.22% | +80,000+14.6% | Added |
| Bank of New York Mellon Corp | 641,063 | $32.4M | 0.01% | +13,904+2.2% | Added |
| Barclays PLC | 644,508 | $32.6M | 0.02% | +4,955+0.8% | Added |
| Northern Trust Corp | 687,986 | $34.8M | 0.01% | −2,738−0.4% | Reduced |
| Royal Bank of Canada | 774,246 | $39.2M | 0.01% | +110,802+16.7% | Added |
| Two Sigma Advisers, LP | 777,011 | $39.3M | 0.09% | +172,700+28.6% | Added |
| Two Sigma Investments, LP | 801,448 | $40.5M | 0.10% | +325,391+68.4% | Added |
| Capital World Investors | 839,463 | $42.5M | 0.01% | 00.0% | Unchanged |
| Camber Capital Management LP | 865,000 | $43.8M | 1.53% | −1,385,000−61.6% | Reduced |
| Millennium Management LLC | 890,325 | $45.0M | 0.04% | +453,202+103.7% | Added |
| JPMorgan Chase & Co | 941,032 | $47.6M | 0.00% | +39,975+4.4% | Added |
| TD Asset Management Inc | 956,852 | $48.4M | 0.05% | +58,000+6.5% | Added |
| Point72 Asset Management, L.P. | 968,800 | $49.0M | 0.15% | +827,300+584.7% | Added |
| Morgan Stanley | 1,090,263 | $55.2M | 0.00% | +56,859+5.5% | Added |
| First Trust Advisors LP | 1,097,730 | $55.5M | 0.06% | −37,249−3.3% | Reduced |
| Norges Bank | 1,171,936 | $59.3M | 0.01% | +18,010+1.6% | Added |
| Deep Track Capital, LP | 1,249,068 | $63.2M | 2.21% | −1,585,001−55.9% | Reduced |
| Charles Schwab Investment Management Inc | 1,275,319 | $64.5M | 0.02% | +33,012+2.7% | Added |
| Adage Capital Partners GP, L.L.C. | 1,385,300 | $70.1M | 0.15% | +318,300+29.8% | Added |
| Farallon Capital Management, L.L.C. | 1,555,020 | $78.7M | 0.49% | +828,020+113.9% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,905,056 | $96.4M | 0.57% | −461,311−19.5% | Reduced |
| OrbiMed Advisors LLC | 2,064,797 | $104.5M | 2.09% | −104,703−4.8% | Reduced |
| Geode Capital Management, LLC | 2,275,931 | $115.2M | 0.01% | +81,200+3.7% | Added |
| BVF Inc | 2,428,613 | $122.9M | 3.07% | −1,576,000−39.4% | Reduced |
| Macquarie Group Ltd | 3,088,235 | $156.2M | 0.18% | +152,311+5.2% | Added |
| Tweedy, Browne Co LLC | 3,454,676 | $174.8M | 8.53% | −55,497−1.6% | Reduced |
| Pictet Asset Management Holding SA | 3,518,317 | $178.0M | 0.20% | +277,383+8.6% | Added |
| State Street Corp | 4,008,797 | $202.8M | 0.01% | +53,768+1.4% | Added |
| Price T Rowe Associates Inc | 4,255,074 | $215.3M | 0.03% | +497,077+13.2% | Added |
| Wellington Management Group LLP | 4,616,978 | $233.6M | 0.04% | +2,856,353+162.2% | Added |
| Clearbridge Investments, LLC | 4,707,480 | $238.2M | 0.20% | −133,215−2.8% | Reduced |
| Bellevue Group AG | 8,713,987 | $440.8M | 6.74% | −519,713−5.6% | Reduced |
| BlackRock Inc. | 9,057,530 | $458.2M | 0.01% | −57,097−0.6% | Reduced |
| T. Rowe Price Investment Management, Inc. | 13,201,453 | $667.9M | 0.43% | +78,398+0.6% | Added |
| Vanguard Group Inc | 14,203,481 | $718.6M | 0.02% | −298,544−2.1% | Reduced |
| FMR LLC | 21,520,872 | $1.09B | 0.08% | +21,950+0.1% | Added |
| Woodline Partners LP | 0 | $0 | 0.00% | −315,094−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −114,600−100.0% | Sold out |
| Boulder Hill Capital Management LP | 0 | $0 | 0.00% | −46,500−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −29,262−100.0% | Sold out |
| Bokf, NA | 0 | $0 | 0.00% | −26,974−100.0% | Sold out |
| Twin Tree Management, LP | 0 | $0 | 0.00% | −20,441−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −19,537−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −16,547−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −16,352−100.0% | Sold out |
| Centiva Capital, LP | 0 | $0 | 0.00% | −13,307−100.0% | Sold out |
| Mirae Asset Global Investments Co., Ltd. | 0 | $0 | 0.00% | −12,042−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −11,300−100.0% | Sold out |
| Waddell & Associates, LLC | 0 | $0 | 0.00% | −10,042−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −8,803−100.0% | Sold out |
| Bridgefront Capital, LLC | 0 | $0 | 0.00% | −4,948−100.0% | Sold out |
| Arden Trust Co | 0 | $0 | 0.00% | −4,792−100.0% | Sold out |
| Wealthcare Advisory Partners LLC | 0 | $0 | 0.00% | −4,613−100.0% | Sold out |
| Toroso Investments, LLC | 0 | $0 | 0.00% | −4,427−100.0% | Sold out |
| Peoples Bank | 0 | $0 | 0.00% | −850−100.0% | Sold out |
| Riverview Trust Co | 0 | $0 | 0.00% | −476−100.0% | Sold out |
| Carolinas Wealth Consulting LLC | 0 | $0 | 0.00% | −161−100.0% | Sold out |
| Leonteq Securities AG | 0 | $0 | 0.00% | −130−100.0% | Sold out |
| Umb Bank N A | 0 | $0 | 0.00% | −101−100.0% | Sold out |
| Legacy Financial Group LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Baker Avenue Asset Management, LP | 0 | $0 | 0.00% | −77−100.0% | Sold out |
| Centerpoint Advisors, LLC | 0 | $0 | 0.00% | −68−100.0% | Sold out |
| Earnest Partners LLC | 0 | $0 | 0.00% | −49−100.0% | Sold out |
| Quilter Plc | 0 | $0 | 0.00% | −363−100.0% | Sold out |
| International Biotechnology Trust PLC | – | – | – | – | Not filed |
| Virginia Retirement Systems Et Al | – | – | – | – | Not filed |
| Icon Wealth Partners, LLC | – | – | – | – | Not filed |
| Johnson Midwest Financial, LLC | – | – | – | – | Not filed |