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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q3 2023

Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
312
+12 vs. Q2 2023
Shares held
139.7M
+6.44M (+4.8%) vs. Q2 2023
Total value
$6.35B
+$878.1M (+16.1%) vs. Q2 2023
New holders
39
101 more added
Sold out
27
103 more reduced

5 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 312 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ3 2023: $6.35B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2023.

Institutions holding IONS in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Pictet Asset Management Holding SA3,240,934$147.0M0.18%+3,240,934New
Tweedy, Browne Co LLC3,510,173$159.2M8.52%−30,685−0.9%Reduced
Price T Rowe Associates Inc3,757,997$170.5M0.03%−77,870−2.0%Reduced
State Street Corp3,955,029$179.4M0.01%−19,424−0.5%Reduced
BVF Inc4,004,613$181.6M4.90%+1,158,598+40.7%Added
Clearbridge Investments, LLC4,840,695$219.6M0.21%−346,509−6.7%Reduced
BlackRock Inc.9,114,627$413.4M0.01%−21,547−0.2%Reduced
Bellevue Group AG9,233,700$418.8M6.75%−146,600−1.6%Reduced
T. Rowe Price Investment Management, Inc.13,123,055$595.3M0.42%+39,328+0.3%Added
Vanguard Group Inc14,502,025$657.8M0.02%−21,241−0.1%Reduced
FMR LLC21,498,922$975.2M0.08%+35,106+0.2%Added
Quilter Plc363––00.0%Unchanged
Thrivent Financial for Lutherans0$00.00%−987,450−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−125,850−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−110,000−100.0%Sold out
Public Sector Pension Investment Board0$00.00%−98,000−100.0%Sold out
Agf Management Ltd0$00.00%−87,867−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−84,961−100.0%Sold out
Bank of Nova Scotia0$00.00%−78,042−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−39,025−100.0%Sold out
Engineers Gate Manager LP0$00.00%−34,047−100.0%Sold out
Vestmark Advisory Solutions, Inc.0$00.00%−23,623−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−23,100−100.0%Sold out
Canada Pension Plan Investment Board0$00.00%−21,019−100.0%Sold out
Aigen Investment Management, LP0$00.00%−16,019−100.0%Sold out
Seven Eight Capital, LP0$00.00%−6,178−100.0%Sold out
MML Investors Services, LLC0$00.00%−5,956−100.0%Sold out
National Asset Management, Inc.0$00.00%−5,615−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−5,348−100.0%Sold out
Teza Capital Management LLC0$00.00%−5,134−100.0%Sold out
Regions Financial Corp0$00.00%−5,110−100.0%Sold out
New England Capital Financial Advisors LLC0$00.00%−1,300−100.0%Sold out
First Manhattan Co0$00.00%−775−100.0%Sold out
HM Payson & Co0$00.00%−360−100.0%Sold out
Stonebridge Capital Advisors LLC0$00.00%−69−100.0%Sold out
Plante Moran Financial Advisors, LLC0$00.00%−40−100.0%Sold out
CVA Family Office, LLC0$00.00%−30−100.0%Sold out
Valley National Advisers Inc0$00.00%−11−100.0%Sold out
Fairfield, Bush & Co.0$00.00%−4−100.0%Sold out
Pictet Asset Management SA––––Not filed
Tekla Capital Management LLC––––Not filed
PFS Investments Inc.––––Not filed
Kistler-Tiffany Companies, LLC––––Not filed
Coastal Capital Group, Inc.––––Not filed