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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
305
−10 vs. Q1 2023
Shares held
136.5M
+5.40M (+4.1%) vs. Q1 2023
Total value
$5.60B
+$907.9M (+19.3%) vs. Q1 2023
New holders
33
97 more added
Sold out
43
111 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 305 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2023: $5.60B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2023.

Institutions holding IONS in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Bellevue Group AG9,380,300$384.9M5.49%−131,600−1.4%Reduced
T. Rowe Price Investment Management, Inc.13,083,727$536.8M0.37%+19,680+0.2%Added
Vanguard Group Inc14,523,266$595.9M0.01%+547,476+3.9%Added
FMR LLC21,463,816$880.7M0.07%+27,482+0.1%Added
Quilter Plc363––00.0%Unchanged
ExodusPoint Capital Management, LP0$00.00%−265,330−100.0%Sold out
Man Group plc0$00.00%–Sold out
Twinbeech Capital LP0$00.00%−136,967−100.0%Sold out
M28 Capital Management LP0$00.00%−126,300−100.0%Sold out
Alberta Investment Management Corp0$00.00%−101,426−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−67,918−100.0%Sold out
Highland Capital Management, LLC0$00.00%−37,598−100.0%Sold out
Caption Management, LLC0$00.00%−27,200−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−27,185−100.0%Sold out
Magnetar Financial LLC0$00.00%−23,652−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−21,227−100.0%Sold out
Federated Hermes, Inc.0$00.00%−18,473−100.0%Sold out
Lincoln National Corp0$00.00%−13,034−100.0%Sold out
Inceptionr LLC0$00.00%−12,790−100.0%Sold out
Illinois Municipal Retirement Fund0$00.00%−11,866−100.0%Sold out
Capital Fund Management S.A.0$00.00%−11,314−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−9,422−100.0%Sold out
Northeast Financial Consultants Inc0$00.00%−7,740−100.0%Sold out
Delphia (USA) Inc.0$00.00%−7,326−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−7,056−100.0%Sold out
HSBC Holdings PLC0$00.00%−6,623−100.0%Sold out
First Republic Investment Management, Inc.0$00.00%−5,896−100.0%Sold out
Kapitalo Investimentos Ltda0$00.00%−3,381−100.0%Sold out
Acadian Asset Management LLC0$00.00%−3,073−100.0%Sold out
Walleye Capital LLC0$00.00%−2,240−100.0%Sold out
Values First Advisors, Inc.0$00.00%−1,594−100.0%Sold out
United Community Bank0$00.00%−1,131−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,019−100.0%Sold out
Belpointe Asset Management LLC0$00.00%−548−100.0%Sold out
Advisory Services Network, LLC0$00.00%−519−100.0%Sold out
Strategic Investment Solutions, Inc.0$00.00%−500−100.0%Sold out
Fred Alger Management, LLC0$00.00%−499−100.0%Sold out
Advent Capital Management0$00.00%−464−100.0%Sold out
Geneos Wealth Management Inc.0$00.00%−400−100.0%Sold out
Ameritas Advisory Services, LLC0$00.00%−191−100.0%Sold out
Loomis Sayles & Co L P0$00.00%−146−100.0%Sold out
Salem Investment Counselors Inc0$00.00%−123−100.0%Sold out
Abound Wealth Management0$00.00%−67−100.0%Sold out
Leonteq Securities AG0$00.00%−55−100.0%Sold out
Jackson, Grant Investment Advisers, Inc.0$00.00%−40−100.0%Sold out
Orion Capital Management LLC0$00.00%−38−100.0%Sold out
TCI Wealth Advisors, Inc.0$00.00%−35−100.0%Sold out
Central Bank & Trust Co0$00.00%−28−100.0%Sold out