Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 350
- −1 vs. Q2 2022
- Shares held
- 126.4M
- +1.80M (+1.4%) vs. Q2 2022
- Total value
- $5.59B
- +$976.9M (+21.2%) vs. Q2 2022
- New holders
- 50
- 97 more added
- Sold out
- 51
- 130 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Cornercap Investment Counsel Inc | 4,703 | $208.0K | 0.04% | +4,703 | New |
| Mitchell & Pahl Private Wealth, LLC | 4,866 | $215.0K | 0.16% | +4,866 | New |
| Ieq Capital, LLC | 4,983 | $220.0K | 0.01% | +4,983 | New |
| Beaird Harris Wealth Management, LLC | 5,000 | $221.0K | 0.05% | +5,000 | New |
| Archford Capital Strategies, LLC | 5,042 | $223.0K | 0.06% | +5,042 | New |
| Buckingham Strategic Wealth, LLC | 5,092 | $225.0K | 0.00% | +5,092 | New |
| Prospera Financial Services Inc | 5,095 | $226.0K | 0.01% | −26,189−83.7% | Reduced |
| Prudential Financial Inc | 5,098 | $226.0K | 0.00% | +5,098 | New |
| JustInvest LLC | 5,209 | $230.0K | 0.01% | −874−14.4% | Reduced |
| M&T Bank Corp | 5,168 | $230.0K | 0.00% | −333−6.1% | Reduced |
| CIBC Asset Management Inc | 5,203 | $230.0K | 0.00% | +5,203 | New |
| Seven Eight Capital, LP | 5,290 | $234.0K | 0.05% | −167−3.1% | Reduced |
| Prelude Capital Management, LLC | 5,341 | $236.0K | 0.01% | −2,087−28.1% | Reduced |
| Regions Financial Corp | 5,346 | $236.0K | 0.00% | +5,346 | New |
| Duality Advisers, LP | 5,792 | $256.0K | 0.03% | +5,792 | New |
| NewEdge Wealth, LLC | 5,854 | $259.0K | 0.01% | −1,461−20.0% | Reduced |
| Echo Street Capital Management LLC | 6,193 | $274.0K | 0.00% | +6,193 | New |
| IFP Advisors, Inc | 5,789 | $279.0K | 0.01% | 00.0% | Unchanged |
| Perkins Capital Management Inc | 6,400 | $283.0K | 0.32% | +6,400 | New |
| ExodusPoint Capital Management, LP | 6,417 | $284.0K | 0.00% | −31,173−82.9% | Reduced |
| Truist Financial Corp | 6,420 | $284.0K | 0.00% | −15,944−71.3% | Reduced |
| Engineers Gate Manager LP | 6,493 | $287.0K | 0.02% | −10,210−61.1% | Reduced |
| First Republic Investment Management, Inc. | 6,670 | $295.0K | 0.00% | +654+10.9% | Added |
| Baird Financial Group, Inc. | 6,772 | $300.0K | 0.00% | −125−1.8% | Reduced |
| Stonegate Investment Group, LLC | 6,807 | $301.0K | 0.01% | −248−3.5% | Reduced |
| Quantamental Technologies LLC | 6,899 | $305.0K | 0.12% | +6,899 | New |
| Virtus ETF Advisers LLC | 7,029 | $311.0K | 0.12% | +104+1.5% | Added |
| Allspring Global Investments Holdings, LLC | 7,045 | $311.0K | 0.00% | +1,526+27.6% | Added |
| Tanaka Capital Management Inc | 7,112 | $315.0K | 0.94% | 00.0% | Unchanged |
| Mariner, LLC | 7,141 | $316.0K | 0.00% | +7,141 | New |
| Northwestern Mutual Wealth Management Co | 7,247 | $320.0K | 0.00% | +268+3.8% | Added |
| National Asset Management, Inc. | 7,332 | $325.0K | 0.01% | −1,070−12.7% | Reduced |
| Commerce Bank | 7,431 | $329.0K | 0.00% | 00.0% | Unchanged |
| Utah Retirement Systems | 7,500 | $332.0K | 0.01% | +100+1.4% | Added |
| AQR Capital Management LLC | 7,710 | $341.0K | 0.00% | +7,710 | New |
| Northeast Financial Consultants Inc | 7,740 | $342.0K | 0.03% | 00.0% | Unchanged |
| Horizon Kinetics Asset Management LLC | 8,000 | $354.0K | 0.01% | 00.0% | Unchanged |
| Quantbot Technologies LP | 8,106 | $358.0K | 0.03% | +6,906+575.5% | Added |
| MetLife Investment Management | 8,287 | $366.5K | 0.00% | 00.0% | Unchanged |
| Independent Financial Group, LLC | 8,325 | $368.2K | 0.03% | +200+2.5% | Added |
| Brandywine Managers, LLC | 8,460 | $374.0K | 1.23% | 00.0% | Unchanged |
| Nicollet Investment Management, Inc. | 8,508 | $376.0K | 0.21% | +66+0.8% | Added |
| Two Sigma Securities, LLC | 8,670 | $383.0K | 0.05% | +2,097+31.9% | Added |
| Wrapmanager Inc | 8,833 | $391.0K | 0.13% | −718−7.5% | Reduced |
| HighTower Advisors, LLC | 8,865 | $393.0K | 0.00% | −623−6.6% | Reduced |
| Stephens Inc | 9,125 | $404.0K | 0.01% | −2,519−21.6% | Reduced |
| Corton Capital Inc. | 9,423 | $417.0K | 0.51% | +1,025+12.2% | Added |
| Delphia (USA) Inc. | 9,597 | $424.0K | 0.48% | +286+3.1% | Added |
| Martingale Asset Management L P | 9,713 | $431.0K | 0.01% | +2,308+31.2% | Added |
| The PNC Financial Services Group, Inc. | 9,829 | $435.0K | 0.00% | −153−1.5% | Reduced |
| Waddell & Associates, LLC | 10,042 | $444.0K | 0.09% | 00.0% | Unchanged |
| American Century Companies Inc | 10,079 | $446.0K | 0.00% | +2,724+37.0% | Added |
| E Fund Management Co., Ltd. | 10,170 | $450.0K | 0.04% | −2,427−19.3% | Reduced |
| Teza Capital Management LLC | 10,248 | $453.0K | 0.09% | −1,977−16.2% | Reduced |
| Brown Advisory Inc | 10,630 | $470.0K | 0.00% | +1,000+10.4% | Added |
| Occudo Quantitative Strategies LP | 10,766 | $476.0K | 0.04% | −50,905−82.5% | Reduced |
| Oppenheimer Asset Management Inc. | 10,834 | $479.0K | 0.01% | −69−0.6% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 10,922 | $483.0K | 0.00% | −200−1.8% | Reduced |
| Hanseatic Management Services Inc | 10,993 | $486.0K | 1.31% | −229−2.0% | Reduced |
| Neuberger Berman Group LLC | 11,199 | $495.0K | 0.00% | +113+1.0% | Added |
| Franklin Resources Inc | 11,251 | $497.0K | 0.00% | +11,251 | New |
| Shell Asset Management Co | 11,265 | $498.0K | 0.02% | −2,951−20.8% | Reduced |
| Plancorp, LLC | 11,255 | $498.0K | 0.03% | +20+0.2% | Added |
| Vontobel Holding Ltd. | 11,282 | $499.0K | 0.01% | −2,928−20.6% | Reduced |
| Advisor Group Holdings, Inc. | 11,535 | $510.0K | 0.00% | −5,889−33.8% | Reduced |
| Comerica Bank | 11,539 | $516.0K | 0.00% | −145−1.2% | Reduced |
| Qube Research & Technologies Ltd | 11,697 | $517.0K | 0.00% | +11,697 | New |
| Tower Research Capital LLC (TRC) | 11,755 | $520.0K | 0.01% | +10,325+722.0% | Added |
| Arden Trust Co | 11,916 | $527.0K | 0.13% | −276−2.3% | Reduced |
| SG Americas Securities, LLC | 12,698 | $562.0K | 0.01% | −59,859−82.5% | Reduced |
| Strategic Wealth Advisors Group, LLC | 12,729 | $563.0K | 0.02% | +639+5.3% | Added |
| Lincoln National Corp | 12,830 | $567.0K | 0.01% | −431−3.3% | Reduced |
| Storebrand Asset Management AS | 13,062 | $577.7K | 0.00% | −9,400−41.8% | Reduced |
| North Star Asset Management Inc | 13,680 | $605.0K | 0.04% | 00.0% | Unchanged |
| Creative Planning | 13,892 | $614.0K | 0.00% | +1,163+9.1% | Added |
| ProShare Advisors LLC | 14,198 | $628.0K | 0.00% | +831+6.2% | Added |
| AlphaCrest Capital Management LLC | 14,770 | $653.0K | 0.04% | −21,677−59.5% | Reduced |
| Blair William & Co | 14,844 | $657.0K | 0.00% | +237+1.6% | Added |
| Profund Advisors LLC | 15,477 | $685.0K | 0.05% | −726−4.5% | Reduced |
| Xponance, Inc. | 15,540 | $687.0K | 0.01% | +122+0.8% | Added |
| Victory Capital Management Inc | 15,795 | $699.0K | 0.00% | +2,249+16.6% | Added |
| Natixis Advisors, L.P. | 15,818 | $700.0K | 0.00% | −12−0.1% | Reduced |
| US Bancorp | 16,198 | $717.0K | 0.00% | −1,125−6.5% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 16,734 | $740.0K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 17,135 | $757.0K | 0.00% | +10,415+155.0% | Added |
| Calamos Advisors LLC | 17,119 | $757.0K | 0.00% | +17,119 | New |
| STRS Ohio | 17,308 | $765.0K | 0.00% | +17,308 | New |
| AtonRa Partners | 17,628 | $780.0K | 0.77% | −518−2.9% | Reduced |
| Handelsbanken Fonder AB | 18,511 | $819.0K | 0.01% | 00.0% | Unchanged |
| Millennium Management LLC | 18,929 | $837.0K | 0.00% | −301,686−94.1% | Reduced |
| SEI Investments Co | 19,129 | $845.0K | 0.00% | +8,503+80.0% | Added |
| Knowledge Leaders Capital, LLC | 19,360 | $856.0K | 1.09% | −15,280−44.1% | Reduced |
| Public Employees Retirement Association of Colorado | 19,604 | $867.0K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 20,390 | $898.0K | 0.00% | +20,390 | New |
| Castle Rock Wealth Management, LLC | 19,885 | $906.0K | 0.46% | +4,292+27.5% | Added |
| Jane Street Group, LLC | 20,629 | $913.0K | 0.00% | −70,260−77.3% | Reduced |
| Ziegler Capital Management, LLC | 20,659 | $914.0K | 0.04% | −120−0.6% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $923.0K | 0.01% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 21,109 | $934.0K | 0.02% | −53,083−71.5% | Reduced |
| Commonwealth Equity Services, LLC | 21,247 | $939.0K | 0.00% | −2,517−10.6% | Reduced |