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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q3 2021

Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
326
−9 vs. Q2 2021
Shares held
121.7M
−2.53M (−2.0%) vs. Q2 2021
Total value
$4.08B
−$872.0M (−17.6%) vs. Q2 2021
New holders
38
108 more added
Sold out
47
103 more reduced

3 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 326 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ3 2021: $4.08B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2021.

Institutions holding IONS in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Parkside Financial Bank & Trust37$2.00K0.00%+14+60.9%Added
Massmutual Trust Co FSB64$2.00K0.00%+64New
PSI Advisors, LLC50$2.00K0.00%+50New
Kelly Financial Services LLC30$1.01K0.00%−1,167−97.5%Reduced
Sargent Bickham Lagudis LLC43$1.00K0.00%00.0%Unchanged
Bedel Financial Consulting, Inc.38$1.00K0.00%00.0%Unchanged
Liberty Wealth Management LLC44$1.00K0.00%00.0%Unchanged
Orion Capital Management LLC38$1.00K0.00%00.0%Unchanged
Covington Capital Management23$1.00K0.00%−13−36.1%Reduced
AdvisorNet Financial, Inc29$1.00K0.00%00.0%Unchanged
Allworth Financial LP17$1.00K0.00%00.0%Unchanged
Cranbrook Wealth Management, LLC25$1.00K0.00%00.0%Unchanged
Stonebridge Capital Advisors LLC29$1.00K0.00%00.0%Unchanged
BDO Wealth Advisors, LLC33$1.00K0.00%00.0%Unchanged
Sound Income Strategies, LLC20$1.00K0.00%00.0%Unchanged
Private Capital Group, LLC31$1.00K0.00%00.0%Unchanged
Focused Wealth Management, Inc16$1.00K0.00%+16New
Meridian Wealth Partners, LLC23$1.00K0.00%+23New
Raffa Wealth Management, LLC28$9390.00%00.0%Unchanged
TD Private Client Wealth LLC11$3690.00%−118−91.5%Reduced
Meeder Asset Management Inc14$00.00%00.0%Unchanged
Huntington National Bank14$00.00%+13+1,300.0%Added
Gemmer Asset Management LLC3$00.00%00.0%Unchanged
Aspire Private Capital, LLC8$00.00%00.0%Unchanged
Ci Investments Inc.8$00.00%+8New
Bell Investment Advisors, Inc10$00.00%+10New
Nomura Asset Management Co Ltd0$00.00%−7,417−100.0%Sold out
Bank Julius Baer & Co. Ltd, Zurich0$00.00%−288,844−100.0%Sold out
Worldquant Millennium Advisors LLC0$00.00%−251,075−100.0%Sold out
Marshall Wace, LLP0$00.00%−176,820−100.0%Sold out
Van Eck Associates Corp0$00.00%−147,383−100.0%Sold out
PDT Partners, LLC0$00.00%−141,925−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−88,273−100.0%Sold out
Jump Financial, LLC0$00.00%−62,400−100.0%Sold out
Seeyond0$00.00%−33,852−100.0%Sold out
Edgestream Partners, L.P.0$00.00%−31,262−100.0%Sold out
Twin Tree Management, LP0$00.00%−29,382−100.0%Sold out
APG Asset Management N.V.0$00.00%−28,200−100.0%Sold out
Brookfield Asset Management Inc.0$00.00%−13,568−100.0%Sold out
AQR Capital Management LLC0$00.00%−13,434−100.0%Sold out
Waddell & Associates, LLC0$00.00%−10,042−100.0%Sold out
HSBC Holdings PLC0$00.00%−9,435−100.0%Sold out
Aigen Investment Management, LP0$00.00%−8,912−100.0%Sold out
Natixis0$00.00%−8,530−100.0%Sold out
USS Investment Management Ltd0$00.00%−8,363−100.0%Sold out
Bridgewater Associates, LP0$00.00%−7,981−100.0%Sold out
Wealthcare Advisory Partners LLC0$00.00%−7,472−100.0%Sold out
Hussman Strategic Advisors, Inc.0$00.00%−7,200−100.0%Sold out
Commerce Bank0$00.00%−6,291−100.0%Sold out
ProVise Management Group, LLC0$00.00%−6,111−100.0%Sold out
III Capital Management0$00.00%−6,000−100.0%Sold out
Wellington Management Group LLP0$00.00%−5,911−100.0%Sold out
Icon Wealth Partners, LLC0$00.00%−5,917−100.0%Sold out
Vident Investment Advisory, LLC0$00.00%−5,587−100.0%Sold out
CIBC Asset Management Inc0$00.00%−5,140−100.0%Sold out
Buckingham Strategic Wealth, LLC0$00.00%−5,078−100.0%Sold out
Weiss Multi-Strategy Advisers LLC0$00.00%−5,073−100.0%Sold out
Credit Agricole S A0$00.00%−4,210−100.0%Sold out
KB Financial Partners, LLC0$00.00%−4,030−100.0%Sold out
Panagora Asset Management Inc0$00.00%−2,329−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−1,484−100.0%Sold out
Wolverine Asset Management LLC0$00.00%−783−100.0%Sold out
S.A. Mason LLC0$00.00%−775−100.0%Sold out
NuWave Investment Management, LLC0$00.00%−551−100.0%Sold out
Advisory Services Network, LLC0$00.00%−519−100.0%Sold out
SkyView Investment Advisors, LLC0$00.00%−271−100.0%Sold out
Brown Brothers Harriman & Co0$00.00%−200−100.0%Sold out
Cordasco Financial Network0$00.00%−200−100.0%Sold out
Loring Wolcott & Coolidge Fiduciary Advisors LLP0$00.00%−45−100.0%Sold out
Harbor Investment Advisory, LLC0$00.00%−38−100.0%Sold out
Clean Yield Group0$00.00%−50−100.0%Sold out
Prestige Wealth Management Group LLC0$00.00%−60−100.0%Sold out
Enterprise Financial Services Corp0$00.00%−23−100.0%Sold out
Pictet Asset Management Ltd––––Not filed
CWM, LLC––––Not filed
First Horizon Corp––––Not filed