Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 326
- −9 vs. Q2 2021
- Shares held
- 121.7M
- −2.53M (−2.0%) vs. Q2 2021
- Total value
- $4.08B
- −$872.0M (−17.6%) vs. Q2 2021
- New holders
- 38
- 108 more added
- Sold out
- 47
- 103 more reduced
3 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Erste Asset Management GmbH | 51,300 | $1.72M | 0.03% | 00.0% | Unchanged |
| Deutsche Bank AG | 50,946 | $1.71M | 0.00% | −183,440−78.3% | Reduced |
| Treasurer of the State of North Carolina | 50,516 | $1.69M | 0.01% | +1,709+3.5% | Added |
| Raymond James Financial Services Advisors, Inc. | 46,156 | $1.55M | 0.00% | +1,325+3.0% | Added |
| International Biotechnology Trust PLC | 44,781 | $1.50M | 0.37% | −137,000−75.4% | Reduced |
| Jefferies Group LLC | 44,137 | $1.48M | 0.04% | −22,567−33.8% | Reduced |
| Private Advisor Group, LLC | 44,105 | $1.48M | 0.01% | +20,664+88.2% | Added |
| Principal Financial Group Inc | 42,685 | $1.43M | 0.00% | −5,285−11.0% | Reduced |
| Voya Investment Management LLC | 42,700 | $1.43M | 0.00% | −719−1.7% | Reduced |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.41M | 0.19% | 00.0% | Unchanged |
| Arrowstreet Capital, Limited Partnership | 41,100 | $1.38M | 0.00% | −51,800−55.8% | Reduced |
| Capital Counsel LLC | 40,580 | $1.36M | 0.07% | 00.0% | Unchanged |
| Gateway Investment Advisers LLC | 38,132 | $1.28M | 0.01% | +532+1.4% | Added |
| Commonwealth Equity Services, LLC | 38,118 | $1.28M | 0.00% | +12,388+48.1% | Added |
| First Foundation Advisors | 35,746 | $1.20M | 0.04% | +1,297+3.8% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 35,536 | $1.19M | 0.01% | +35,536 | New |
| Storebrand Asset Management AS | 34,666 | $1.16M | 0.01% | −756−2.1% | Reduced |
| Arizona State Retirement System | 34,557 | $1.16M | 0.01% | +96+0.3% | Added |
| Janney Montgomery Scott LLC | 34,153 | $1.15M | 0.00% | −4,493−11.6% | Reduced |
| ProShare Advisors LLC | 33,499 | $1.12M | 0.00% | +3,076+10.1% | Added |
| Macquarie Group Ltd | 32,428 | $1.09M | 0.00% | 00.0% | Unchanged |
| Employees Retirement System of Texas | 32,409 | $1.09M | 0.01% | 00.0% | Unchanged |
| Group One Trading, L.P. | 31,533 | $1.06M | 0.02% | +30.0% | Added |
| Truist Financial Corp | 30,977 | $1.04M | 0.00% | +5,876+23.4% | Added |
| Kestra Advisory Services, LLC | 27,924 | $937.0K | 0.01% | +5,078+22.2% | Added |
| Simplex Trading, LLC | 22,512 | $901.0K | 0.03% | +1,158+5.4% | Added |
| Eaton Vance Management | 26,874 | $885.0K | 0.00% | −200−0.7% | Reduced |
| BNP Paribas Arbitrage, SA | 25,732 | $863.1K | 0.00% | +4,465+21.0% | Added |
| Amalgamated Bank | 25,401 | $852.0K | 0.01% | −1,532−5.7% | Reduced |
| Utah Retirement Systems | 25,309 | $849.0K | 0.01% | −1,400−5.2% | Reduced |
| MML Investors Services, LLC | 24,614 | $826.0K | 0.01% | +1,828+8.0% | Added |
| Handelsbanken Fonder AB | 24,411 | $819.0K | 0.00% | 00.0% | Unchanged |
| Algert Global LLC | 23,474 | $787.0K | 0.10% | +23,474 | New |
| Profund Advisors LLC | 22,891 | $768.0K | 0.03% | −1,167−4.9% | Reduced |
| Sphera Funds Management Ltd. | 22,000 | $738.0K | 0.07% | +22,000 | New |
| Grandfield & Dodd, LLC | 21,691 | $730.0K | 0.05% | +638+3.0% | Added |
| Stephens Inc | 21,141 | $709.0K | 0.01% | −4,497−17.5% | Reduced |
| Oppenheimer & Co Inc | 21,127 | $709.0K | 0.01% | −221−1.0% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $700.0K | 0.00% | −11,415−35.3% | Reduced |
| Vestmark Advisory Solutions, Inc. | 20,033 | $672.0K | 0.05% | +146+0.7% | Added |
| Campbell & CO Investment Adviser LLC | 19,896 | $667.0K | 0.22% | +19,896 | New |
| Teacher Retirement System of Texas | 19,760 | $663.0K | 0.00% | +2,242+12.8% | Added |
| Allianz Asset Management GmbH | 19,710 | $661.0K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 19,721 | $661.0K | 0.00% | +8,472+75.3% | Added |
| Public Employees Retirement Association of Colorado | 19,604 | $658.0K | 0.00% | 00.0% | Unchanged |
| SG3 Management, LLC | 18,500 | $620.0K | 0.22% | −53,800−74.4% | Reduced |
| Advisor Group Holdings, Inc. | 18,441 | $619.0K | 0.00% | −2,462−11.8% | Reduced |
| Alexandria Capital, LLC | 18,362 | $616.0K | 0.06% | +65+0.4% | Added |
| Natixis Advisors, L.P. | 17,728 | $595.0K | 0.00% | −1,136−6.0% | Reduced |
| State of Wisconsin Investment Board | 17,579 | $590.0K | 0.00% | +830+5.0% | Added |
| Cambridge Investment Research Advisors, Inc. | 16,867 | $566.0K | 0.00% | −2,407−12.5% | Reduced |
| Emerald Advisers, LLC | 16,815 | $564.0K | 0.02% | −806−4.6% | Reduced |
| Tanaka Capital Management Inc | 16,661 | $559.0K | 0.80% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 16,672 | $559.0K | 0.03% | +16,672 | New |
| US Bancorp | 16,383 | $550.0K | 0.00% | +2,375+17.0% | Added |
| Castle Rock Wealth Management, LLC | 15,593 | $544.0K | 0.19% | 00.0% | Unchanged |
| Arden Trust Co | 16,097 | $540.0K | 0.09% | +104+0.7% | Added |
| AGF Investments LLC | 15,936 | $534.0K | 0.05% | −1,353−7.8% | Reduced |
| Brown Advisory Securities, LLC | 15,500 | $521.0K | 0.15% | +2,000+14.8% | Added |
| Walleye Capital LLC | 15,470 | $519.0K | 0.02% | +15,470 | New |
| Optimal Asset Management, Inc. | 15,118 | $507.0K | 0.06% | 00.0% | Unchanged |
| Creative Planning | 14,915 | $500.0K | 0.00% | +1,595+12.0% | Added |
| Xponance, Inc. | 14,572 | $489.0K | 0.01% | −654−4.3% | Reduced |
| Blair William & Co | 14,514 | $487.0K | 0.00% | +4,226+41.1% | Added |
| Lincoln National Corp | 14,270 | $479.0K | 0.01% | −800−5.3% | Reduced |
| Janus Henderson Group PLC | 13,748 | $461.0K | 0.00% | +13,748 | New |
| North Star Asset Management Inc | 13,680 | $459.0K | 0.03% | −73−0.5% | Reduced |
| JustInvest LLC | 13,544 | $454.0K | 0.04% | +13,544 | New |
| Victory Capital Management Inc | 13,339 | $447.0K | 0.00% | −877−6.2% | Reduced |
| Trexquant Investment LP | 13,297 | $446.0K | 0.04% | +13,297 | New |
| Berkshire Asset Management LLC | 13,060 | $438.0K | 0.03% | +1,661+14.6% | Added |
| Cowen and Company, LLC | 12,843 | $431.0K | 0.02% | −14,865−53.6% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,817 | $430.0K | 0.00% | 00.0% | Unchanged |
| Shell Asset Management Co | 12,603 | $423.0K | 0.01% | −566−4.3% | Reduced |
| Cetera Advisor Networks LLC | 12,552 | $421.0K | 0.01% | +4,335+52.8% | Added |
| Bank of Nova Scotia | 12,315 | $413.0K | 0.00% | −1,220−9.0% | Reduced |
| Virtus ETF Advisers LLC | 12,102 | $406.0K | 0.18% | −1,110−8.4% | Reduced |
| SEI Investments Co | 13,957 | $401.0K | 0.00% | −95−0.7% | Reduced |
| HAP Trading, LLC | 11,877 | $398.0K | 0.03% | +11,877 | New |
| Virginia Retirement Systems Et Al | 11,700 | $392.0K | 0.00% | +11,700 | New |
| Dynamic Technology Lab Private Ltd | 11,500 | $386.0K | 0.05% | +11,500 | New |
| Koss-Olinger Consulting, LLC | 11,432 | $383.0K | 0.06% | +11,432 | New |
| Brookstone Capital Management | 11,397 | $382.0K | 0.01% | +11,397 | New |
| National Asset Management, Inc. | 11,018 | $379.0K | 0.01% | −188−1.7% | Reduced |
| Plancorp, LLC | 11,134 | $373.0K | 0.03% | +14+0.1% | Added |
| Ameriprise Financial Inc | 10,899 | $366.0K | 0.00% | +974+9.8% | Added |
| Oppenheimer Asset Management Inc. | 10,882 | $365.0K | 0.01% | +165+1.5% | Added |
| Comerica Bank | 11,830 | $360.0K | 0.00% | −3,761−24.1% | Reduced |
| Nicollet Investment Management, Inc. | 10,501 | $352.0K | 0.15% | −30.0% | Reduced |
| Wrapmanager Inc | 10,324 | $346.0K | 0.09% | −259−2.4% | Reduced |
| Maryland State Retirement & Pension System | 9,956 | $336.0K | 0.01% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 9,857 | $334.0K | 0.00% | +554+6.0% | Added |
| Mackenzie Financial Corp | 9,783 | $328.0K | 0.00% | 00.0% | Unchanged |
| Bard Financial Services, Inc. | 9,725 | $326.0K | 0.03% | +9,725 | New |
| Walleye Trading LLC | 9,619 | $323.0K | 0.01% | +9,619 | New |
| Regions Financial Corp | 9,423 | $316.0K | 0.00% | 00.0% | Unchanged |
| Baird Financial Group, Inc. | 8,949 | $300.0K | 0.00% | +1,553+21.0% | Added |
| KBC Group NV | 8,912 | $299.0K | 0.00% | −2,899−24.5% | Reduced |
| Metropolitan Life Insurance Co | 8,880 | $297.8K | 0.00% | −293−3.2% | Reduced |
| The PNC Financial Services Group, Inc. | 8,799 | $294.0K | 0.00% | −548−5.9% | Reduced |