Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 326
- −9 vs. Q2 2021
- Shares held
- 121.7M
- −2.53M (−2.0%) vs. Q2 2021
- Total value
- $4.08B
- −$872.0M (−17.6%) vs. Q2 2021
- New holders
- 38
- 108 more added
- Sold out
- 47
- 103 more reduced
3 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nuveen Asset Management, LLC | 628,476 | $21.1M | 0.01% | −94,625−13.1% | Reduced |
| Northern Trust Corp | 655,421 | $22.0M | 0.00% | −16,152−2.4% | Reduced |
| Nikko Asset Management Americas, Inc. | 675,301 | $22.6M | 0.10% | +166,927+32.8% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 685,660 | $23.0M | 0.01% | +161,334+30.8% | Added |
| Bank of America Corp | 710,117 | $23.8M | 0.00% | −7,380−1.0% | Reduced |
| Candriam Luxembourg S.C.A. | 726,359 | $24.4M | 0.17% | +173,793+31.5% | Added |
| Wells Fargo & Company | 853,370 | $28.6M | 0.01% | +11,939+1.4% | Added |
| Citadel Advisors LLC | 1,049,857 | $35.2M | 0.04% | +504,377+92.5% | Added |
| Charles Schwab Investment Management Inc | 1,069,732 | $35.9M | 0.01% | +355,772+49.8% | Added |
| Swedbank AB | 1,117,339 | $37.5M | 0.07% | +640.0% | Added |
| Norges Bank | 1,146,918 | $38.5M | 0.01% | +250,629+28.0% | Added |
| Jacobs Levy Equity Management, Inc | 1,191,236 | $40.0M | 0.27% | +106,814+9.8% | Added |
| Rockefeller Capital Management L.P. | 1,332,780 | $44.7M | 0.23% | +8,169+0.6% | Added |
| Thrivent Financial for Lutherans | 1,387,764 | $46.5M | 0.09% | +1,264,397+1,024.9% | Added |
| First Trust Advisors LP | 1,680,549 | $56.4M | 0.06% | +158,100+10.4% | Added |
| Geode Capital Management, LLC | 1,772,767 | $59.5M | 0.01% | +10,227+0.6% | Added |
| JPMorgan Chase & Co | 2,416,313 | $81.0M | 0.01% | +140,607+6.2% | Added |
| Camber Capital Management LP | 2,500,000 | $83.8M | 3.12% | +500,000+25.0% | Added |
| State Street Corp | 3,521,314 | $118.1M | 0.01% | +290,363+9.0% | Added |
| Clearbridge Investments, LLC | 7,327,322 | $245.8M | 0.18% | +511,721+7.5% | Added |
| BlackRock Inc. | 8,119,853 | $272.3M | 0.01% | −59,813−0.7% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 8,511,384 | $285.5M | 0.69% | −396,349−4.4% | Reduced |
| Bellevue Group AG | 9,347,926 | $313.5M | 3.18% | −582,319−5.9% | Reduced |
| Price T Rowe Associates Inc | 11,737,321 | $393.7M | 0.04% | −521,506−4.3% | Reduced |
| Vanguard Group Inc | 11,800,009 | $395.8M | 0.01% | −855,820−6.8% | Reduced |
| FMR LLC | 21,172,154 | $710.1M | 0.06% | +27,699+0.1% | Added |
| Nomura Asset Management Co Ltd | 0 | $0 | 0.00% | −7,417−100.0% | Sold out |
| Bank Julius Baer & Co. Ltd, Zurich | 0 | $0 | 0.00% | −288,844−100.0% | Sold out |
| Worldquant Millennium Advisors LLC | 0 | $0 | 0.00% | −251,075−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −176,820−100.0% | Sold out |
| Van Eck Associates Corp | 0 | $0 | 0.00% | −147,383−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −141,925−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −88,273−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −62,400−100.0% | Sold out |
| Seeyond | 0 | $0 | 0.00% | −33,852−100.0% | Sold out |
| Edgestream Partners, L.P. | 0 | $0 | 0.00% | −31,262−100.0% | Sold out |
| Twin Tree Management, LP | 0 | $0 | 0.00% | −29,382−100.0% | Sold out |
| APG Asset Management N.V. | 0 | $0 | 0.00% | −28,200−100.0% | Sold out |
| Brookfield Asset Management Inc. | 0 | $0 | 0.00% | −13,568−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −13,434−100.0% | Sold out |
| Waddell & Associates, LLC | 0 | $0 | 0.00% | −10,042−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −9,435−100.0% | Sold out |
| Aigen Investment Management, LP | 0 | $0 | 0.00% | −8,912−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −8,530−100.0% | Sold out |
| USS Investment Management Ltd | 0 | $0 | 0.00% | −8,363−100.0% | Sold out |
| Bridgewater Associates, LP | 0 | $0 | 0.00% | −7,981−100.0% | Sold out |
| Wealthcare Advisory Partners LLC | 0 | $0 | 0.00% | −7,472−100.0% | Sold out |
| Hussman Strategic Advisors, Inc. | 0 | $0 | 0.00% | −7,200−100.0% | Sold out |
| Commerce Bank | 0 | $0 | 0.00% | −6,291−100.0% | Sold out |
| ProVise Management Group, LLC | 0 | $0 | 0.00% | −6,111−100.0% | Sold out |
| III Capital Management | 0 | $0 | 0.00% | −6,000−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −5,911−100.0% | Sold out |
| Icon Wealth Partners, LLC | 0 | $0 | 0.00% | −5,917−100.0% | Sold out |
| Vident Investment Advisory, LLC | 0 | $0 | 0.00% | −5,587−100.0% | Sold out |
| CIBC Asset Management Inc | 0 | $0 | 0.00% | −5,140−100.0% | Sold out |
| Buckingham Strategic Wealth, LLC | 0 | $0 | 0.00% | −5,078−100.0% | Sold out |
| Weiss Multi-Strategy Advisers LLC | 0 | $0 | 0.00% | −5,073−100.0% | Sold out |
| Credit Agricole S A | 0 | $0 | 0.00% | −4,210−100.0% | Sold out |
| KB Financial Partners, LLC | 0 | $0 | 0.00% | −4,030−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −2,329−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −1,484−100.0% | Sold out |
| Wolverine Asset Management LLC | 0 | $0 | 0.00% | −783−100.0% | Sold out |
| S.A. Mason LLC | 0 | $0 | 0.00% | −775−100.0% | Sold out |
| NuWave Investment Management, LLC | 0 | $0 | 0.00% | −551−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −519−100.0% | Sold out |
| SkyView Investment Advisors, LLC | 0 | $0 | 0.00% | −271−100.0% | Sold out |
| Brown Brothers Harriman & Co | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Cordasco Financial Network | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 0 | $0 | 0.00% | −45−100.0% | Sold out |
| Harbor Investment Advisory, LLC | 0 | $0 | 0.00% | −38−100.0% | Sold out |
| Clean Yield Group | 0 | $0 | 0.00% | −50−100.0% | Sold out |
| Prestige Wealth Management Group LLC | 0 | $0 | 0.00% | −60−100.0% | Sold out |
| Enterprise Financial Services Corp | 0 | $0 | 0.00% | −23−100.0% | Sold out |
| Pictet Asset Management Ltd | – | – | – | – | Not filed |
| CWM, LLC | – | – | – | – | Not filed |
| First Horizon Corp | – | – | – | – | Not filed |