Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 169
- −1 vs. Q4 2025
- Shares held
- 71.7M
- +7.83M (+12.3%) vs. Q4 2025
- Total value
- $550.1M
- −$172.3M (−23.9%) vs. Q4 2025
- New holders
- 37
- 74 more added
- Sold out
- 38
- 38 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 61,041 | $468.2K | 0.00% | +53,350+693.7% | Added |
| Creative Planning | 64,089 | $491.6K | 0.00% | +41,985+189.9% | Added |
| Rhumbline Advisers | 66,175 | $507.6K | 0.00% | +10,462+18.8% | Added |
| Atom Investors LP | 69,155 | $530.4K | 0.04% | +8,560+14.1% | Added |
| RBF Capital, LLC | 70,000 | $536.9K | 0.03% | −10,506−13.0% | Reduced |
| XTX Topco Ltd | 71,603 | $549.2K | 0.01% | +19,801+38.2% | Added |
| Russell Investments Group, Ltd. | 79,157 | $607.1K | 0.00% | +75,583+2,114.8% | Added |
| Price T Rowe Associates Inc | 80,169 | $615.0K | 0.00% | +16,409+25.7% | Added |
| Barclays PLC | 88,458 | $678.5K | 0.00% | −44,083−33.3% | Reduced |
| Susquehanna International Group, LLP | 101,336 | $777.2K | 0.00% | +13,406+15.2% | Added |
| Invesco Ltd. | 111,125 | $852.3K | 0.00% | −306,064−73.4% | Reduced |
| Simplify Asset Management Inc. | 115,994 | $889.7K | 0.01% | −43,680−27.4% | Reduced |
| Wellington Management Group LLP | 118,600 | $909.7K | 0.00% | −27,827−19.0% | Reduced |
| Engineers Gate Manager LP | 126,109 | $967.3K | 0.01% | +126,109 | New |
| Bank of America Corp | 126,559 | $970.7K | 0.00% | −104,618−45.3% | Reduced |
| Nuveen, LLC | 129,618 | $994.2K | 0.00% | +17,415+15.5% | Added |
| ADAR1 Capital Management, LLC | 130,560 | $1.00M | 0.06% | −1,123,189−89.6% | Reduced |
| Fiduciary Trust Co | 136,555 | $1.05M | 0.01% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 136,664 | $1.05M | 0.07% | +36,955+37.1% | Added |
| Two Sigma Investments, LP | 139,000 | $1.07M | 0.00% | +139,000 | New |
| Bank of New York Mellon Corp | 149,942 | $1.15M | 0.00% | +33,036+28.3% | Added |
| Y-Intercept (Hong Kong) Ltd | 153,344 | $1.18M | 0.02% | +86,628+129.8% | Added |
| State of Wisconsin Investment Board | 154,435 | $1.18M | 0.00% | +67,936+78.5% | Added |
| American Century Companies Inc | 156,242 | $1.20M | 0.00% | −1,430−0.9% | Reduced |
| Morgan Stanley | 173,337 | $1.33M | 0.00% | +7,714+4.7% | Added |
| Squarepoint Ops LLC | 175,944 | $1.35M | 0.00% | +110,092+167.2% | Added |
| DAFNA Capital Management LLC | 205,000 | $1.57M | 0.36% | +205,000 | New |
| Panagora Asset Management Inc | 243,565 | $1.87M | 0.01% | +243,565 | New |
| Bessemer Group Inc | 286,988 | $2.20M | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 303,988 | $2.33M | 0.05% | −213,538−41.3% | Reduced |
| Jane Street Group, LLC | 310,417 | $2.38M | 0.00% | −183,333−37.1% | Reduced |
| UBS Group AG | 315,185 | $2.42M | 0.00% | +212,218+206.1% | Added |
| Vanguard Fiduciary Trust Co | 329,884 | $2.53M | 0.00% | +329,884 | New |
| Millennium Management LLC | 356,471 | $2.73M | 0.00% | +302,040+554.9% | Added |
| Jump Financial, LLC | 369,805 | $2.84M | 0.04% | +277,605+301.1% | Added |
| Adage Capital Partners GP, L.L.C. | 400,000 | $3.07M | 0.00% | −1,300,000−76.5% | Reduced |
| Silverarc Capital Management, LLC | 419,949 | $3.22M | 0.38% | +25,299+6.4% | Added |
| Charles Schwab Investment Management Inc | 426,869 | $3.27M | 0.00% | +37,973+9.8% | Added |
| Trexquant Investment LP | 453,529 | $3.48M | 0.03% | +97,982+27.6% | Added |
| Northern Trust Corp | 472,985 | $3.63M | 0.00% | −79,235−14.3% | Reduced |
| AQR Capital Management LLC | 543,165 | $4.17M | 0.00% | +527,663+3,403.8% | Added |
| Goldman Sachs Group Inc | 571,909 | $4.39M | 0.00% | +248,030+76.6% | Added |
| Vanguard Portfolio Management LLC | 599,379 | $4.60M | 0.00% | +599,379 | New |
| Acadian Asset Management LLC | 727,315 | $5.57M | 0.01% | −9,425−1.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 736,684 | $5.65M | 0.01% | +154,307+26.5% | Added |
| Qube Research & Technologies Ltd | 974,739 | $7.48M | 0.01% | +582,250+148.3% | Added |
| Ikarian Capital, LLC | 1,049,161 | $8.05M | 1.15% | −326,311−23.7% | Reduced |
| Vestal Point Capital, LP | 1,100,000 | $8.44M | 0.24% | +150,000+15.8% | Added |
| Dimensional Fund Advisors LP | 1,130,281 | $8.66M | 0.00% | +79,157+7.5% | Added |
| Assenagon Asset Management S.A. | 1,193,873 | $9.16M | 0.01% | +1,193,873 | New |
| Citadel Advisors LLC | 1,292,486 | $9.91M | 0.01% | +85,482+7.1% | Added |
| Alyeska Investment Group, L.P. | 1,328,449 | $10.2M | 0.03% | +1,328,449 | New |
| Geode Capital Management, LLC | 1,486,542 | $11.4M | 0.00% | +380,729+34.4% | Added |
| State Street Corp | 1,549,851 | $11.9M | 0.00% | +544,506+54.2% | Added |
| D. E. Shaw & Co., Inc. | 1,623,281 | $12.5M | 0.01% | −290,474−15.2% | Reduced |
| Jones Hill Capital LP | 1,771,926 | $13.6M | 2.91% | +1,771,926 | New |
| Balyasny Asset Management LLC | 1,779,946 | $13.7M | 0.03% | +809,507+83.4% | Added |
| GSK plc | 1,785,714 | $13.7M | 2.29% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 2,074,855 | $15.9M | 0.03% | −323,377−13.5% | Reduced |
| Standard Life Aberdeen plc | 2,211,953 | $17.0M | 0.03% | +957,926+76.4% | Added |
| First Turn Management, LLC | 2,256,109 | $17.3M | 1.93% | +363,426+19.2% | Added |
| Siren, L.L.C. | 2,350,000 | $18.0M | 0.50% | +400,000+20.5% | Added |
| Vanguard Capital Management LLC | 2,692,948 | $20.7M | 0.00% | +2,692,948 | New |
| Nantahala Capital Management, LLC | 3,050,040 | $23.4M | 1.46% | −1,243,306−29.0% | Reduced |
| Braidwell LP | 3,134,922 | $24.0M | 0.80% | +73,700+2.4% | Added |
| TCG Crossover Management, LLC | 5,250,000 | $40.3M | 1.15% | 00.0% | Unchanged |
| BlackRock, Inc. | 5,390,593 | $41.3M | 0.00% | +1,126,832+26.4% | Added |
| Ra Capital Management, L.P. | 6,053,960 | $46.4M | 0.49% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 6,561,111 | $50.3M | 1.36% | 00.0% | Unchanged |
| Great Point Partners LLC | 0 | $0 | 0.00% | −800,000−100.0% | Sold out |
| Sio Capital Management, LLC | 0 | $0 | 0.00% | −382,000−100.0% | Sold out |
| Driehaus Capital Management LLC | 0 | $0 | 0.00% | −243,388−100.0% | Sold out |
| Catalio Capital Management, LP | 0 | $0 | 0.00% | −201,301−100.0% | Sold out |
| Nicholas Investment Partners, LP | 0 | $0 | 0.00% | −182,961−100.0% | Sold out |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −138,143−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −108,434−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −102,921−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −100,675−100.0% | Sold out |
| Maven Securities LTD | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Principal Financial Group Inc | 0 | $0 | 0.00% | −97,688−100.0% | Sold out |
| Exome Asset Management LLC | 0 | $0 | 0.00% | −92,055−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −74,691−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −72,060−100.0% | Sold out |
| Legato Capital Management LLC | 0 | $0 | 0.00% | −66,347−100.0% | Sold out |
| Integrated Quantitative Investments LLC | 0 | $0 | 0.00% | −62,522−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −61,620−100.0% | Sold out |
| DekaBank Deutsche Girozentrale | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| KVP Capital Advisors, LP | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Seven Grand Managers, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −41,260−100.0% | Sold out |
| SEI Investments Co | 0 | $0 | 0.00% | −37,511−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −35,601−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −30,500−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −28,832−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −25,568−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −17,165−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −16,791−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −14,294−100.0% | Sold out |
| Alphabet Inc. | 0 | $0 | 0.00% | −14,262−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −9,658−100.0% | Sold out |