Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 294
- +28 vs. Q1 2026
- Shares held
- 156.2M
- +8.88M (+6.0%) vs. Q1 2026
- Total value
- $4.00B
- +$1.18B (+41.8%) vs. Q1 2026
- New holders
- 56
- 120 more added
- Sold out
- 28
- 68 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sector Gamma AS | 0 | $0 | 0.00% | −162,710−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −78,007−100.0% | Sold out |
| Polen Capital Management LLC | 0 | $0 | 0.00% | −65,301−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −43,362−100.0% | Sold out |
| Seven Fleet Capital Management LP | 0 | $0 | 0.00% | −35,286−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −32,147−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −23,000−100.0% | Sold out |
| Amundi | 0 | $0 | 0.00% | −18,604−100.0% | Sold out |
| Perbak Capital Partners LLP | 0 | $0 | 0.00% | −13,175−100.0% | Sold out |
| Headlands Technologies LLC | 0 | $0 | 0.00% | −10,557−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −848−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −758−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −512−100.0% | Sold out |
| GWM Advisors LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Eastern Bank | 0 | $0 | 0.00% | −282−100.0% | Sold out |
| Root Financial Partners, LLC | 0 | $0 | 0.00% | −188−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −246−100.0% | Sold out |
| Golden State Equity Partners | 0 | $0 | 0.00% | −130−100.0% | Sold out |
| Your Advocates Ltd., LLP | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Wealth Preservation Advisors, LLC | 0 | $0 | 0.00% | −43−100.0% | Sold out |
| Vermillion Wealth Management, Inc. | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Curio Wealth, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Janus Henderson Group PLC | – | – | – | – | Not filed |
| CWM, LLC | – | – | – | – | Not filed |
| Sunbelt Securities, Inc. | – | – | – | – | Not filed |