Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 231
- +10 vs. Q1 2025
- Shares held
- 137.6M
- +1.67M (+1.2%) vs. Q1 2025
- Total value
- $1.93B
- +$76.1M (+4.1%) vs. Q1 2025
- New holders
- 46
- 84 more added
- Sold out
- 36
- 64 more reduced
1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avion Wealth | 40 | $0 | 0.00% | +15+60.0% | Added |
| Hemington Wealth Management | 34 | $0 | 0.00% | +18+112.5% | Added |
| Bay Harbor Wealth Management, LLC | 1 | $13 | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 1 | $18 | 0.00% | +1 | New |
| Rialto Wealth Management, LLC | 2 | $28 | 0.00% | +2 | New |
| Global Retirement Partners, LLC | 3 | $42 | 0.00% | +3 | New |
| HFM Investment Advisors, LLC | 3 | $42 | 0.00% | +3 | New |
| SJS Investment Consulting Inc. | 4 | $56 | 0.00% | +1+33.3% | Added |
| SBI Securities Co., Ltd. | 5 | $70 | 0.00% | 00.0% | Unchanged |
| Private Wealth Asset Management, LLC | 8 | $112 | 0.00% | −30−78.9% | Reduced |
| WealthTrak Capital Management LLC | 10 | $140 | 0.00% | +10 | New |
| Skopos Labs, Inc. | 31 | $434 | 0.00% | +31 | New |
| CIBC Private Wealth Group, LLC | 35 | $490 | 0.00% | +35 | New |
| Bare Financial Services, Inc | 36 | $504 | 0.00% | +36 | New |
| Ronald Blue Trust, Inc. | 40 | $560 | 0.00% | +40 | New |
| Fortitude Family Office, LLC | 41 | $574 | 0.00% | +41 | New |
| SRS Capital Advisors, Inc. | 52 | $728 | 0.00% | +52 | New |
| True Wealth Design, LLC | 56 | $784 | 0.00% | +56 | New |
| Rise Advisors, LLC | 74 | $1.03K | 0.00% | +74 | New |
| Harbour Investments, Inc. | 100 | $1.40K | 0.00% | 00.0% | Unchanged |
| Your Advocates Ltd., LLP | 100 | $1.40K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 107 | $1.50K | 0.00% | +100+1,428.6% | Added |
| EverSource Wealth Advisors, LLC | 115 | $1.61K | 0.00% | −316−73.3% | Reduced |
| Massmutual Trust Co FSB | 123 | $1.72K | 0.00% | −25−16.9% | Reduced |
| Bell Investment Advisors, Inc | 123 | $1.72K | 0.00% | +71+136.5% | Added |
| UMA Financial Services, Inc. | 140 | $1.96K | 0.00% | +140 | New |
| Parkside Financial Bank & Trust | 150 | $2.10K | 0.00% | +150 | New |
| National Bank of Canada | 172 | $2.40K | 0.00% | +102+145.7% | Added |
| Caitong International Asset Management Co., Ltd | 200 | $2.80K | 0.00% | −1,911−90.5% | Reduced |
| Mount Yale Investment Advisors, LLC | 201 | $2.81K | 0.00% | +201 | New |
| City State Bank | 250 | $3.50K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 270 | $3.78K | 0.00% | −423−61.0% | Reduced |
| Allworth Financial LP | 275 | $3.85K | 0.00% | −28−9.2% | Reduced |
| Private Wealth Management Group, LLC | 296 | $4.14K | 0.00% | +296 | New |
| Rothschild Investment LLC | 325 | $4.55K | 0.00% | +260+400.0% | Added |
| Signaturefd, LLC | 329 | $4.60K | 0.00% | −196−37.3% | Reduced |
| GWM Advisors LLC | 400 | $5.60K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 441 | $6.17K | 0.00% | −93−17.4% | Reduced |
| Smartleaf Asset Management LLC | 454 | $6.40K | 0.00% | −19−4.0% | Reduced |
| NBC Securities, Inc. | 532 | $7.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 475 | $7.00K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 545 | $7.63K | 0.00% | +383+236.4% | Added |
| Covestor Ltd | 580 | $8.00K | 0.00% | −1−0.2% | Reduced |
| Nemes Rush Group LLC | 700 | $9.79K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 749 | $10.5K | 0.00% | +164+28.0% | Added |
| Optiver Holding B.V. | 893 | $12.5K | 0.00% | +862+2,780.6% | Added |
| IFP Advisors, Inc | 0 | $13.5K | 0.00% | 0 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $14.0K | 0.00% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,139 | $16.0K | 0.00% | +1,139 | New |
| Nisa Investment Advisors, LLC | 1,217 | $17.0K | 0.00% | −199−14.1% | Reduced |
| Comerica Bank | 1,284 | $18.0K | 0.00% | +100+8.4% | Added |
| Versant Capital Management, Inc | 1,286 | $18.0K | 0.00% | +570+79.6% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 1,369 | $19.2K | 0.00% | +1,369 | New |
| Bartlett & Co. Wealth Management LLC | 1,500 | $21.0K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 1,595 | $22.2K | 0.00% | +547+52.2% | Added |
| Headlands Technologies LLC | 1,847 | $25.8K | 0.00% | +1,847 | New |
| State of Wyoming | 2,099 | $29.4K | 0.00% | +2,099 | New |
| CWM, LLC | 2,275 | $32.0K | 0.00% | +251+12.4% | Added |
| Simplex Trading, LLC | 2,502 | $35.0K | 0.00% | +2,502 | New |
| Russell Investments Group, Ltd. | 2,558 | $35.8K | 0.00% | −83−3.1% | Reduced |
| Sterling Capital Management LLC | 3,386 | $47.4K | 0.00% | +2,397+242.4% | Added |
| Assetmark, Inc | 3,620 | $50.6K | 0.00% | +435+13.7% | Added |
| GF Fund Management Co. Ltd. | 3,685 | $51.6K | 0.00% | 00.0% | Unchanged |
| Shell Asset Management Co | 4,009 | $56.0K | 0.00% | −447−10.0% | Reduced |
| Amalgamated Bank | 4,305 | $60.0K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 4,495 | $63.0K | 0.00% | −1,955−30.3% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 5,612 | $78.5K | 0.00% | +753+15.5% | Added |
| Virtus Investment Advisers, Inc. | 6,300 | $88.1K | 0.03% | −691−9.9% | Reduced |
| The PNC Financial Services Group, Inc. | 8,236 | $115.2K | 0.00% | +4,494+120.1% | Added |
| HSBC Holdings PLC | 10,048 | $141.2K | 0.00% | −47,955−82.7% | Reduced |
| Xponance, Inc. | 10,352 | $144.8K | 0.00% | +10,352 | New |
| MONECO Advisors, LLC | 10,478 | $146.6K | 0.01% | −122−1.2% | Reduced |
| Aigen Investment Management, LP | 10,662 | $149.2K | 0.02% | +10,662 | New |
| Public Employees Retirement Association of Colorado | 12,238 | $171.0K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 13,434 | $188.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 13,522 | $189.2K | 0.01% | +930+7.4% | Added |
| E Fund Management Co., Ltd. | 13,612 | $190.4K | 0.01% | +1,543+12.8% | Added |
| Tower Research Capital LLC (TRC) | 13,669 | $191.2K | 0.01% | +10,457+325.6% | Added |
| Caxton Associates LLP | 14,229 | $199.1K | 0.01% | +14,229 | New |
| STRS Ohio | 14,300 | $200.1K | 0.00% | −9,500−39.9% | Reduced |
| Jain Global LLC | 14,486 | $202.7K | 0.00% | +14,486 | New |
| Empowered Funds, LLC | 14,820 | $207.3K | 0.00% | −5,819−28.2% | Reduced |
| NEOS Investment Management LLC | 15,174 | $212.3K | 0.00% | 00.0% | Unchanged |
| Tema ETFs LLC | 15,174 | $212.3K | 0.06% | 00.0% | Unchanged |
| JustInvest LLC | 15,329 | $214.5K | 0.00% | +15,329 | New |
| Prelude Capital Management, LLC | 15,940 | $223.0K | 0.02% | +15,940 | New |
| CIBC World Markets Corp | 16,318 | $228.3K | 0.00% | −11,264−40.8% | Reduced |
| Prudential Financial Inc | 16,878 | $236.1K | 0.00% | −21,765−56.3% | Reduced |
| Breakwater Capital Group | 17,096 | $239.2K | 0.04% | +2,081+13.9% | Added |
| Virtu Financial LLC | 18,438 | $258.0K | 0.01% | +18,438 | New |
| BNP Paribas Arbitrage, SA | 19,082 | $267.0K | 0.00% | +10,367+119.0% | Added |
| Two Sigma Investments, LP | 19,300 | $270.0K | 0.00% | −83,103−81.2% | Reduced |
| AQR Capital Management LLC | 21,217 | $296.8K | 0.00% | +21,217 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 21,484 | $300.6K | 0.00% | +2,785+14.9% | Added |
| Capital Fund Management S.A. | 21,871 | $306.0K | 0.00% | +21,871 | New |
| HighTower Advisors, LLC | 22,533 | $315.2K | 0.00% | −1,070−4.5% | Reduced |
| Quest Partners LLC | 22,964 | $321.3K | 0.03% | −2,096−8.4% | Reduced |
| Cinctive Capital Management LP | 24,310 | $340.1K | 0.02% | +24,310 | New |
| KLP Kapitalforvaltning AS | 26,100 | $365.1K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 26,596 | $372.1K | 0.00% | +662+2.6% | Added |