Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 222
- +1 vs. Q4 2024
- Shares held
- 135.9M
- +8.35M (+6.5%) vs. Q4 2024
- Total value
- $1.85B
- −$751.0M (−28.9%) vs. Q4 2024
- New holders
- 36
- 74 more added
- Sold out
- 35
- 80 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SG Americas Securities, LLC | 48,365 | $658.0K | 0.00% | +37,362+339.6% | Added |
| MAI Capital Management | 46,526 | $632.5K | 0.00% | 00.0% | Unchanged |
| Pier 88 Investment Partners LLC | 44,910 | $610.6K | 0.12% | −500−1.1% | Reduced |
| Walleye Capital LLC | 44,138 | $600.1K | 0.01% | +19,318+77.8% | Added |
| Employees Retirement System of Texas | 43,769 | $595.0K | 0.01% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 43,245 | $587.9K | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 43,005 | $584.7K | 0.02% | +22,299+107.7% | Added |
| Victory Capital Management Inc | 41,627 | $565.9K | 0.00% | +3,119+8.1% | Added |
| Knights of Columbus Asset Advisors LLC | 40,275 | $547.5K | 0.04% | +1,058+2.7% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 39,757 | $540.5K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 38,643 | $525.2K | 0.00% | −71,950−65.1% | Reduced |
| Handelsbanken Fonder AB | 38,300 | $521.0K | 0.00% | 00.0% | Unchanged |
| Pathstone Holdings, LLC | 38,305 | $520.7K | 0.00% | +17,081+80.5% | Added |
| Arizona State Retirement System | 37,112 | $504.5K | 0.00% | −283−0.8% | Reduced |
| Two Sigma Advisers, LP | 35,300 | $479.9K | 0.00% | +20,200+133.8% | Added |
| Teacher Retirement System of Texas | 34,857 | $473.9K | 0.00% | −3,321−8.7% | Reduced |
| State Board of Administration of Florida Retirement System | 34,168 | $464.5K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 33,461 | $454.9K | 0.00% | −8,364−20.0% | Reduced |
| Dana Investment Advisors, Inc. | 32,155 | $437.1K | 0.02% | −2,147−6.3% | Reduced |
| Envestnet Asset Management Inc | 31,430 | $427.3K | 0.00% | −6,192−16.5% | Reduced |
| Creative Planning | 30,564 | $415.5K | 0.00% | −17,386−36.3% | Reduced |
| Erste Asset Management GmbH | 26,900 | $397.6K | 0.01% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 29,128 | $396.0K | 0.04% | −1,389−4.6% | Reduced |
| Profund Advisors LLC | 27,869 | $378.9K | 0.02% | −866−3.0% | Reduced |
| VELA Investment Management, LLC | 27,771 | $377.5K | 0.13% | +12,136+77.6% | Added |
| CIBC World Markets Corp | 27,582 | $375.0K | 0.00% | +15,949+137.1% | Added |
| Police & Firemen's Retirement System of New Jersey | 26,479 | $360.0K | 0.00% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 26,100 | $354.8K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 25,934 | $352.6K | 0.00% | −209−0.8% | Reduced |
| Quest Partners LLC | 25,060 | $340.7K | 0.04% | +18,099+260.0% | Added |
| STRS Ohio | 23,800 | $323.6K | 0.00% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 23,603 | $320.9K | 0.00% | −2,535−9.7% | Reduced |
| Polar Asset Management Partners Inc. | 20,952 | $284.8K | 0.01% | −530,140−96.2% | Reduced |
| Empowered Funds, LLC | 20,639 | $280.6K | 0.00% | +2,052+11.0% | Added |
| Cetera Investment Advisers | 19,993 | $271.8K | 0.00% | −2,707−11.9% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 18,699 | $254.2K | 0.00% | +18,699 | New |
| SEI Investments Co | 17,276 | $234.9K | 0.00% | −6,771−28.2% | Reduced |
| Engineers Gate Manager LP | 17,198 | $233.8K | 0.00% | −36,160−67.8% | Reduced |
| Balyasny Asset Management LLC | 16,595 | $225.6K | 0.00% | −399,479−96.0% | Reduced |
| NEOS Investment Management LLC | 15,174 | $206.3K | 0.00% | +15,174 | New |
| Tema ETFs LLC | 15,174 | $206.3K | 0.06% | +15,174 | New |
| Breakwater Capital Group | 15,015 | $204.1K | 0.04% | +15,015 | New |
| Royal Bank of Canada | 14,436 | $196.0K | 0.00% | −3,075−17.6% | Reduced |
| Oxford Asset Management LLP | 14,249 | $193.7K | 0.09% | +14,249 | New |
| ADAR1 Capital Management, LLC | 13,873 | $188.6K | 0.04% | −30,953−69.1% | Reduced |
| Verition Fund Management LLC | 13,729 | $186.6K | 0.00% | −8,872−39.3% | Reduced |
| XTX Topco Ltd | 13,485 | $183.3K | 0.01% | −2,602−16.2% | Reduced |
| Great West Life Assurance Co | 13,434 | $183.0K | 0.00% | 00.0% | Unchanged |
| Bridgefront Capital, LLC | 13,084 | $177.9K | 0.05% | +13,084 | New |
| Ameritas Investment Partners, Inc. | 12,592 | $171.2K | 0.01% | 00.0% | Unchanged |
| Pitcairn Co | 12,423 | $168.9K | 0.01% | +1,125+10.0% | Added |
| Public Employees Retirement Association of Colorado | 12,238 | $166.0K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 12,069 | $164.1K | 0.01% | +2,072+20.7% | Added |
| Entropy Technologies, LP | 11,215 | $152.5K | 0.01% | +11,215 | New |
| MONECO Advisors, LLC | 10,600 | $144.1K | 0.01% | 00.0% | Unchanged |
| Bayesian Capital Management, LP | 10,130 | $137.7K | 0.02% | −8,690−46.2% | Reduced |
| BNP Paribas Arbitrage, SA | 8,715 | $118.5K | 0.00% | −7,228−45.3% | Reduced |
| Virtus Investment Advisers, Inc. | 6,991 | $95.0K | 0.03% | +6,991 | New |
| KBC Group NV | 6,450 | $88.0K | 0.00% | +116+1.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 4,859 | $71.8K | 0.00% | +63+1.3% | Added |
| Shell Asset Management Co | 4,456 | $61.0K | 0.00% | +4,456 | New |
| Amalgamated Bank | 4,305 | $59.0K | 0.00% | +113+2.7% | Added |
| The PNC Financial Services Group, Inc. | 3,742 | $50.9K | 0.00% | −48−1.3% | Reduced |
| GF Fund Management Co. Ltd. | 3,685 | $50.1K | 0.00% | +663+21.9% | Added |
| Tower Research Capital LLC (TRC) | 3,212 | $43.7K | 0.00% | −8,076−71.5% | Reduced |
| Assetmark, Inc | 3,185 | $43.3K | 0.00% | −494−13.4% | Reduced |
| BI Asset Management Fondsmaeglerselskab A/S | 2,988 | $41.0K | 0.00% | +2,988 | New |
| Russell Investments Group, Ltd. | 2,641 | $35.9K | 0.00% | −19,475−88.1% | Reduced |
| Caitong International Asset Management Co., Ltd | 2,111 | $28.7K | 0.02% | +1,551+277.0% | Added |
| CWM, LLC | 2,024 | $28.0K | 0.00% | −378−15.7% | Reduced |
| Bartlett & Co. Wealth Management LLC | 1,500 | $20.4K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 1,416 | $19.3K | 0.00% | −65,205−97.9% | Reduced |
| Comerica Bank | 1,184 | $16.1K | 0.00% | +89+8.1% | Added |
| Riverview Trust Co | 1,171 | $15.9K | 0.02% | +1,171 | New |
| Advisor Group Holdings, Inc. | 1,048 | $14.3K | 0.00% | −545−34.2% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $13.6K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 989 | $13.4K | 0.00% | −784−44.2% | Reduced |
| Versant Capital Management, Inc | 716 | $9.73K | 0.00% | +513+252.7% | Added |
| Nemes Rush Group LLC | 700 | $9.52K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 693 | $9.42K | 0.00% | +100+16.9% | Added |
| Covestor Ltd | 581 | $8.00K | 0.01% | +2+0.3% | Added |
| GAMMA Investing LLC | 585 | $7.95K | 0.00% | −1,663−74.0% | Reduced |
| US Bancorp | 534 | $7.26K | 0.00% | −479−47.3% | Reduced |
| Signaturefd, LLC | 525 | $7.14K | 0.00% | −78−12.9% | Reduced |
| Quadrant Capital Group LLC | 515 | $7.00K | 0.00% | +515 | New |
| NBC Securities, Inc. | 532 | $7.00K | 0.00% | +532 | New |
| Smartleaf Asset Management LLC | 473 | $6.99K | 0.00% | −592−55.6% | Reduced |
| Daiwa Securities Group Inc. | 475 | $6.00K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 431 | $5.86K | 0.00% | +135+45.6% | Added |
| Umb Bank N A | 416 | $5.66K | 0.00% | +34+8.9% | Added |
| GWM Advisors LLC | 400 | $5.44K | 0.00% | +400 | New |
| Allworth Financial LP | 303 | $4.69K | 0.00% | +293+2,930.0% | Added |
| City State Bank | 250 | $3.40K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 162 | $2.20K | 0.00% | +63+63.6% | Added |
| Lindbrook Capital, LLC | 153 | $2.08K | 0.00% | −102−40.0% | Reduced |
| Massmutual Trust Co FSB | 148 | $2.01K | 0.00% | −6−3.9% | Reduced |
| Coldstream Capital Management Inc | 145 | $1.97K | 0.00% | +145 | New |
| Your Advocates Ltd., LLP | 100 | $1.36K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 100 | $1.36K | 0.00% | +100 | New |
| Sherman Asset Management, Inc. | 94 | $1.28K | 0.00% | 00.0% | Unchanged |