Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 222
- +1 vs. Q4 2024
- Shares held
- 135.9M
- +8.35M (+6.5%) vs. Q4 2024
- Total value
- $1.85B
- −$751.0M (−28.9%) vs. Q4 2024
- New holders
- 36
- 74 more added
- Sold out
- 35
- 80 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Hemington Wealth Management | 16 | $0 | 0.00% | +5+45.5% | Added |
| Avion Wealth | 25 | $0 | 0.00% | +25 | New |
| Bay Harbor Wealth Management, LLC | 1 | $13 | 0.00% | +1 | New |
| DiNuzzo Private Wealth, Inc. | 2 | $28 | 0.00% | +2 | New |
| SJS Investment Consulting Inc. | 3 | $41 | 0.00% | +3 | New |
| SBI Securities Co., Ltd. | 5 | $68 | 0.00% | 00.0% | Unchanged |
| Global Financial Private Client, LLC | 5 | $68 | 0.00% | +3+150.0% | Added |
| Farther Finance Advisors, LLC | 7 | $86 | 0.00% | −28−80.0% | Reduced |
| Boston Private Wealth LLC | 11 | $150 | 0.00% | +11 | New |
| Hexagon Capital Partners LLC | 15 | $204 | 0.00% | +3+25.0% | Added |
| Principal Securities, Inc. | 14 | $285 | 0.00% | 00.0% | Unchanged |
| First Horizon Advisors, Inc. | 25 | $339 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 25 | $340 | 0.00% | 00.0% | Unchanged |
| South State Corp. | 30 | $408 | 0.00% | +30 | New |
| Stephens Consulting, LLC | 30 | $408 | 0.00% | +30 | New |
| Optiver Holding B.V. | 31 | $421 | 0.00% | +31 | New |
| Private Wealth Asset Management, LLC | 38 | $517 | 0.00% | +38 | New |
| Bell Investment Advisors, Inc | 52 | $707 | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 65 | $884 | 0.00% | −35−35.0% | Reduced |
| Sierra Ocean, LLC | 66 | $897 | 0.00% | +66 | New |
| National Bank of Canada | 70 | $952 | 0.00% | +63+900.0% | Added |
| Amundi | 88 | $1.13K | 0.00% | +3+3.5% | Added |
| Sherman Asset Management, Inc. | 94 | $1.28K | 0.00% | 00.0% | Unchanged |
| Your Advocates Ltd., LLP | 100 | $1.36K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 100 | $1.36K | 0.00% | +100 | New |
| Coldstream Capital Management Inc | 145 | $1.97K | 0.00% | +145 | New |
| Massmutual Trust Co FSB | 148 | $2.01K | 0.00% | −6−3.9% | Reduced |
| Lindbrook Capital, LLC | 153 | $2.08K | 0.00% | −102−40.0% | Reduced |
| Parallel Advisors, LLC | 162 | $2.20K | 0.00% | +63+63.6% | Added |
| City State Bank | 250 | $3.40K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 303 | $4.69K | 0.00% | +293+2,930.0% | Added |
| GWM Advisors LLC | 400 | $5.44K | 0.00% | +400 | New |
| Umb Bank N A | 416 | $5.66K | 0.00% | +34+8.9% | Added |
| EverSource Wealth Advisors, LLC | 431 | $5.86K | 0.00% | +135+45.6% | Added |
| Daiwa Securities Group Inc. | 475 | $6.00K | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 473 | $6.99K | 0.00% | −592−55.6% | Reduced |
| NBC Securities, Inc. | 532 | $7.00K | 0.00% | +532 | New |
| Quadrant Capital Group LLC | 515 | $7.00K | 0.00% | +515 | New |
| Signaturefd, LLC | 525 | $7.14K | 0.00% | −78−12.9% | Reduced |
| US Bancorp | 534 | $7.26K | 0.00% | −479−47.3% | Reduced |
| GAMMA Investing LLC | 585 | $7.95K | 0.00% | −1,663−74.0% | Reduced |
| Covestor Ltd | 581 | $8.00K | 0.01% | +2+0.3% | Added |
| Huntington National Bank | 693 | $9.42K | 0.00% | +100+16.9% | Added |
| Nemes Rush Group LLC | 700 | $9.52K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 716 | $9.73K | 0.00% | +513+252.7% | Added |
| Sterling Capital Management LLC | 989 | $13.4K | 0.00% | −784−44.2% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $13.6K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 1,048 | $14.3K | 0.00% | −545−34.2% | Reduced |
| Riverview Trust Co | 1,171 | $15.9K | 0.02% | +1,171 | New |
| Comerica Bank | 1,184 | $16.1K | 0.00% | +89+8.1% | Added |
| Nisa Investment Advisors, LLC | 1,416 | $19.3K | 0.00% | −65,205−97.9% | Reduced |
| Bartlett & Co. Wealth Management LLC | 1,500 | $20.4K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 2,024 | $28.0K | 0.00% | −378−15.7% | Reduced |
| Caitong International Asset Management Co., Ltd | 2,111 | $28.7K | 0.02% | +1,551+277.0% | Added |
| Russell Investments Group, Ltd. | 2,641 | $35.9K | 0.00% | −19,475−88.1% | Reduced |
| BI Asset Management Fondsmaeglerselskab A/S | 2,988 | $41.0K | 0.00% | +2,988 | New |
| Assetmark, Inc | 3,185 | $43.3K | 0.00% | −494−13.4% | Reduced |
| Tower Research Capital LLC (TRC) | 3,212 | $43.7K | 0.00% | −8,076−71.5% | Reduced |
| GF Fund Management Co. Ltd. | 3,685 | $50.1K | 0.00% | +663+21.9% | Added |
| The PNC Financial Services Group, Inc. | 3,742 | $50.9K | 0.00% | −48−1.3% | Reduced |
| Amalgamated Bank | 4,305 | $59.0K | 0.00% | +113+2.7% | Added |
| Shell Asset Management Co | 4,456 | $61.0K | 0.00% | +4,456 | New |
| Mirae Asset Global Investments Co., Ltd. | 4,859 | $71.8K | 0.00% | +63+1.3% | Added |
| KBC Group NV | 6,450 | $88.0K | 0.00% | +116+1.8% | Added |
| Virtus Investment Advisers, Inc. | 6,991 | $95.0K | 0.03% | +6,991 | New |
| BNP Paribas Arbitrage, SA | 8,715 | $118.5K | 0.00% | −7,228−45.3% | Reduced |
| Bayesian Capital Management, LP | 10,130 | $137.7K | 0.02% | −8,690−46.2% | Reduced |
| MONECO Advisors, LLC | 10,600 | $144.1K | 0.01% | 00.0% | Unchanged |
| Entropy Technologies, LP | 11,215 | $152.5K | 0.01% | +11,215 | New |
| E Fund Management Co., Ltd. | 12,069 | $164.1K | 0.01% | +2,072+20.7% | Added |
| Public Employees Retirement Association of Colorado | 12,238 | $166.0K | 0.00% | 00.0% | Unchanged |
| Pitcairn Co | 12,423 | $168.9K | 0.01% | +1,125+10.0% | Added |
| Ameritas Investment Partners, Inc. | 12,592 | $171.2K | 0.01% | 00.0% | Unchanged |
| Bridgefront Capital, LLC | 13,084 | $177.9K | 0.05% | +13,084 | New |
| Great West Life Assurance Co | 13,434 | $183.0K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 13,485 | $183.3K | 0.01% | −2,602−16.2% | Reduced |
| Verition Fund Management LLC | 13,729 | $186.6K | 0.00% | −8,872−39.3% | Reduced |
| ADAR1 Capital Management, LLC | 13,873 | $188.6K | 0.04% | −30,953−69.1% | Reduced |
| Oxford Asset Management LLP | 14,249 | $193.7K | 0.09% | +14,249 | New |
| Royal Bank of Canada | 14,436 | $196.0K | 0.00% | −3,075−17.6% | Reduced |
| Breakwater Capital Group | 15,015 | $204.1K | 0.04% | +15,015 | New |
| NEOS Investment Management LLC | 15,174 | $206.3K | 0.00% | +15,174 | New |
| Tema ETFs LLC | 15,174 | $206.3K | 0.06% | +15,174 | New |
| Balyasny Asset Management LLC | 16,595 | $225.6K | 0.00% | −399,479−96.0% | Reduced |
| Engineers Gate Manager LP | 17,198 | $233.8K | 0.00% | −36,160−67.8% | Reduced |
| SEI Investments Co | 17,276 | $234.9K | 0.00% | −6,771−28.2% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 18,699 | $254.2K | 0.00% | +18,699 | New |
| Cetera Investment Advisers | 19,993 | $271.8K | 0.00% | −2,707−11.9% | Reduced |
| Empowered Funds, LLC | 20,639 | $280.6K | 0.00% | +2,052+11.0% | Added |
| Polar Asset Management Partners Inc. | 20,952 | $284.8K | 0.01% | −530,140−96.2% | Reduced |
| HighTower Advisors, LLC | 23,603 | $320.9K | 0.00% | −2,535−9.7% | Reduced |
| STRS Ohio | 23,800 | $323.6K | 0.00% | 00.0% | Unchanged |
| Quest Partners LLC | 25,060 | $340.7K | 0.04% | +18,099+260.0% | Added |
| Raymond James Financial Inc | 25,934 | $352.6K | 0.00% | −209−0.8% | Reduced |
| KLP Kapitalforvaltning AS | 26,100 | $354.8K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 26,479 | $360.0K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Corp | 27,582 | $375.0K | 0.00% | +15,949+137.1% | Added |
| VELA Investment Management, LLC | 27,771 | $377.5K | 0.13% | +12,136+77.6% | Added |
| Profund Advisors LLC | 27,869 | $378.9K | 0.02% | −866−3.0% | Reduced |
| China Universal Asset Management Co., Ltd. | 29,128 | $396.0K | 0.04% | −1,389−4.6% | Reduced |