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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
203
−6 vs. Q1 2024
Shares held
123.9M
+3.03M (+2.5%) vs. Q1 2024
Total value
$2.88B
+$396.3M (+16.0%) vs. Q1 2024
New holders
29
84 more added
Sold out
35
60 more reduced

2 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 203 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2024: $2.88B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2024.

Institutions holding DNLI in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc11,312,439$262.7M0.01%+344,146+3.1%Added
BlackRock Inc.13,174,562$305.9M0.01%+974,706+8.0%Added
Baillie Gifford & Co13,763,596$319.6M0.25%−277,632−2.0%Reduced
Flagship Pioneering Inc.0$00.00%−1,364,516−100.0%Sold out
Gilder Gagnon Howe & Co LLC0$00.00%−1,172,785−100.0%Sold out
T. Rowe Price Investment Management, Inc.0$00.00%−498,969−100.0%Sold out
Polar Capital Holdings Plc0$00.00%−452,669−100.0%Sold out
ARCH Venture Management, LLC0$00.00%−381,249−100.0%Sold out
Altitude Crest Partners Inc.0$00.00%−209,613−100.0%Sold out
Twinbeech Capital LP0$00.00%−177,364−100.0%Sold out
Edgestream Partners, L.P.0$00.00%−112,118−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−69,314−100.0%Sold out
American International Group, Inc.0$00.00%−58,847−100.0%Sold out
Bamco Inc0$00.00%−50,500−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−47,000−100.0%Sold out
Bank of Montreal0$00.00%−42,288−100.0%Sold out
EP Wealth Advisors, LLC0$00.00%−40,500−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−37,749−100.0%Sold out
LPL Financial LLC0$00.00%−34,085−100.0%Sold out
University of Texas/Texas Am Investment Managment Co0$00.00%−30,428−100.0%Sold out
Harvest Investment Services, LLC0$00.00%−27,978−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−21,900−100.0%Sold out
Seven Eight Capital, LP0$00.00%−20,541−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−19,741−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−15,400−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−12,081−100.0%Sold out
AQR Capital Management LLC0$00.00%−11,001−100.0%Sold out
Mackenzie Financial Corp0$00.00%−10,560−100.0%Sold out
Group One Trading, L.P.0$00.00%−8,455−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−6,471−100.0%Sold out
Fernwood Investment Management, LLC0$00.00%−5,000−100.0%Sold out
Lazard Asset Management LLC0$00.00%−4,410−100.0%Sold out
Headlands Technologies LLC0$00.00%−4,295−100.0%Sold out
New Covenant Trust Company, N.A.0$00.00%−784−100.0%Sold out
Nelson, Van Denburg & Campbell Wealth Management Group, LLC0$00.00%−153−100.0%Sold out
Naples Money Management LLC0$00.00%−45−100.0%Sold out
Financial Synergies Wealth Advisors, Inc.0$00.00%−36−100.0%Sold out
Capital Advisors, Ltd. LLC0$00.00%−6−100.0%Sold out
Credit Suisse AG––––Not filed
Cutler Group LP––––Not filed