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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
195
−6 vs. Q2 2023
Shares held
108.6M
+2.04M (+1.9%) vs. Q2 2023
Total value
$2.24B
−$898.3M (−28.6%) vs. Q2 2023
New holders
29
77 more added
Sold out
35
57 more reduced

2 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 195 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ3 2023: $2.24B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2023.

Institutions holding DNLI in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
XTX Topco Ltd44,656$921.3K0.16%+44,656New
ClariVest Asset Management LLC42,901$885.0K0.05%+38+0.1%Added
Trexquant Investment LP42,349$873.7K0.02%−24,586−36.7%Reduced
Tudor Investment Corp Et Al42,020$866.9K0.01%+42,020New
Profund Advisors LLC40,154$828.4K0.05%−6,321−13.6%Reduced
Jane Street Group, LLC38,739$799.2K0.00%−34,061−46.8%Reduced
Capula Management Ltd38,720$798.8K0.05%+38,720New
Knights of Columbus Asset Advisors LLC38,128$786.6K0.07%+1,151+3.1%Added
Capstone Investment Advisors, LLC37,567$775.0K0.02%+37,567New
Gsa Capital Partners LLP37,404$772.0K0.07%+37,404New
Concentric Wealth Management, LLC36,486$752.7K0.25%00.0%Unchanged
SG Americas Securities, LLC35,800$739.0K0.01%+26,326+277.9%Added
State Board of Administration of Florida Retirement System33,718$695.6K0.00%+180+0.5%Added
Erste Asset Management GmbH334,669$683.9K0.01%+307,769+1,144.1%Added
Arizona State Retirement System31,181$643.3K0.01%+469+1.5%Added
Teacher Retirement System of Texas31,102$642.0K0.00%+1,437+4.8%Added
Y-Intercept (Hong Kong) Ltd26,618$549.1K0.05%+26,618New
Bartlett & Co. LLC24,800$512.0K0.01%+3,260+15.1%Added
Bartlett & Co. Wealth Management LLC24,800$511.6K0.01%+3,260+15.1%Added
Dana Investment Advisors, Inc.24,629$508.1K0.03%−2,430−9.0%Reduced
ProShare Advisors LLC24,332$502.0K0.00%+109+0.4%Added
Engineers Gate Manager LP23,609$487.1K0.02%−8,211−25.8%Reduced
Envestnet Asset Management Inc23,121$477.0K0.00%+7,498+48.0%Added
Dynamic Technology Lab Private Ltd23,089$476.0K0.05%+23,089New
Zurcher Kantonalbank (Zurich Cantonalbank)20,679$426.6K0.00%+2,124+11.4%Added
Healthcare of Ontario Pension Plan Trust Fund20,200$416.7K0.00%+20,200New
VELA Investment Management, LLC19,899$410.5K0.18%−773−3.7%Reduced
Jump Financial, LLC19,787$408.2K0.02%+19,787New
Gotham Asset Management, LLC19,391$400.0K0.01%+19,391New
Aquatic Capital Management LLC18,300$378.0K0.02%+16,300+815.0%Added
Amalgamated Bank18,255$377.0K0.00%+679+3.9%Added
Ironwood Investment Management LLC18,096$373.3K0.23%−623−3.3%Reduced
Royal Bank of Canada17,974$371.0K0.00%+7,458+70.9%Added
Nisa Investment Advisors, LLC17,960$370.5K0.00%+10+0.1%Added
HSBC Holdings PLC17,427$359.4K0.00%+17,427New
ExodusPoint Capital Management, LP17,381$359.0K0.00%+17,381New
Campbell & CO Investment Adviser LLC17,258$356.0K0.04%+17,258New
Handelsbanken Fonder AB17,200$355.0K0.00%00.0%Unchanged
Allianz Asset Management GmbH14,700$303.3K0.00%00.0%Unchanged
Creative Planning14,416$297.4K0.00%+215+1.5%Added
Levin Capital Strategies, L.P.14,000$288.8K0.04%+6,500+86.7%Added
Bayesian Capital Management, LP13,942$287.6K0.03%+13,942New
STRS Ohio13,800$284.0K0.00%00.0%Unchanged
Qube Research & Technologies Ltd13,553$279.6K0.00%+13,553New
Arthur M. Cohen & Associates, LLC12,941$267.0K0.07%−8,189−38.8%Reduced
Jefferies Financial Group Inc.12,800$264.1K0.01%+12,800New
Stifel Financial Corp12,354$254.9K0.00%−905−6.8%Reduced
SEI Investments Co12,260$252.9K0.00%−4,261−25.8%Reduced
Public Employees Retirement Association of Colorado12,238$252.0K0.00%00.0%Unchanged
HRT Financial LP12,205$251.0K0.00%+12,205New
Victory Capital Management Inc12,081$249.2K0.00%+630+5.5%Added
E Fund Management Co., Ltd.11,781$243.0K0.02%−1,580−11.8%Reduced
Ameritas Investment Partners, Inc.11,738$242.2K0.01%+1,982+20.3%Added
Virginia Retirement Systems Et Al11,600$239.3K0.00%+1,200+11.5%Added
Teza Capital Management LLC10,818$223.2K0.04%+10,818New
Lazard Asset Management LLC10,861$223.0K0.00%+5,916+119.6%Added
Prelude Capital Management, LLC10,304$212.6K0.02%−335−3.1%Reduced
Raymond James & Associates9,894$204.1K0.00%−137−1.4%Reduced
Great West Life Assurance Co9,724$200.0K0.00%+5,400+124.9%Added
Metropolitan Life Insurance Co6,806$140.4K0.01%+354+5.5%Added
Allspring Global Investments Holdings, LLC5,166$106.6K0.00%−327−6.0%Reduced
Advisor Group Holdings, Inc.4,677$96.5K0.00%+2,478+112.7%Added
China Universal Asset Management Co., Ltd.3,526$72.7K0.02%+1,732+96.5%Added
Virtus ETF Advisers LLC3,045$62.8K0.04%−304−9.1%Reduced
KBC Group NV2,465$51.0K0.00%+2,465New
Assetmark, Inc2,148$44.3K0.00%+707+49.1%Added
Tower Research Capital LLC (TRC)1,708$35.2K0.00%−4,282−71.5%Reduced
The PNC Financial Services Group, Inc.1,679$34.6K0.00%−292−14.8%Reduced
US Bancorp840$17.3K0.00%+255+43.6%Added
Nemes Rush Group LLC700$14.4K0.00%00.0%Unchanged
CWM, LLC635$13.0K0.00%−22−3.3%Reduced
Signaturefd, LLC626$12.9K0.00%+300+92.0%Added
Daiwa Securities Group Inc.546$11.0K0.00%00.0%Unchanged
Huntington National Bank355$7.32K0.00%−98−21.6%Reduced
Parallel Advisors, LLC320$6.60K0.00%+292+1,042.9%Added
Comerica Bank318$6.57K0.00%+318New
Umb Bank N A306$6.31K0.00%00.0%Unchanged
Covestor Ltd290$6.00K0.00%−1−0.3%Reduced
NBC Securities, Inc.335$6.00K0.00%+335New
City State Bank250$5.00K0.00%00.0%Unchanged
Lindbrook Capital, LLC239$4.93K0.00%−403−62.8%Reduced
First Horizon Advisors, Inc.220$4.54K0.00%−11−4.8%Reduced
EverSource Wealth Advisors, LLC216$4.46K0.00%+172+390.9%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.145$2.99K0.00%+145New
Activest Wealth Management131$2.70K0.00%00.0%Unchanged
Your Advocates Ltd., LLP100$2.06K0.00%00.0%Unchanged
Allworth Financial LP49$1.01K0.00%+49New
Glassman Wealth Services46$9490.00%+46New
Bell Investment Advisors, Inc43$8880.00%−21−32.8%Reduced
Massmutual Trust Co FSB33$6810.00%+11+50.0%Added
Tfo-TDC, LLC12$3540.00%+12New
Institutional & Family Asset Management, LLC11$2270.00%00.0%Unchanged
Quadrant Capital Group LLC7$1450.00%+7New
Global Retirement Partners, LLC3$620.00%00.0%Unchanged
Toronto Dominion Bank2$410.00%00.0%Unchanged
Avidity Partners Management LP0$00.00%−282,752−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−223,471−100.0%Sold out
Platinum Investment Management Ltd0$00.00%−55,341−100.0%Sold out
Hamilton Lane Advisors LLC0$00.00%−52,129−100.0%Sold out
Bellevue Group AG0$00.00%−44,050−100.0%Sold out