Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 202
- +4 vs. Q4 2022
- Shares held
- 108.0M
- +2.13M (+2.0%) vs. Q4 2022
- Total value
- $2.49B
- −$456.7M (−15.5%) vs. Q4 2022
- New holders
- 26
- 92 more added
- Sold out
- 22
- 51 more reduced
1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| American International Group, Inc. | 52,530 | $1.21M | 0.01% | +1,046+2.0% | Added |
| Tudor Investment Corp Et Al | 55,346 | $1.27M | 0.02% | +5,415+10.8% | Added |
| Platinum Investment Management Ltd | 55,341 | $1.28M | 0.04% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 56,244 | $1.30M | 0.01% | −8,447−13.1% | Reduced |
| Engineers Gate Manager LP | 56,785 | $1.31M | 0.05% | +56,785 | New |
| MetLife Investment Management | 57,027 | $1.31M | 0.01% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 59,800 | $1.32M | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 66,978 | $1.54M | 0.00% | +12,371+22.7% | Added |
| Two Sigma Investments, LP | 75,741 | $1.75M | 0.01% | +1,306+1.8% | Added |
| State of New Jersey Common Pension Fund D | 78,253 | $1.80M | 0.01% | 00.0% | Unchanged |
| Trexquant Investment LP | 80,524 | $1.86M | 0.05% | +57,669+252.3% | Added |
| Russell Investments Group, Ltd. | 82,295 | $1.90M | 0.00% | −17,078−17.2% | Reduced |
| Invesco Ltd. | 82,937 | $1.91M | 0.00% | −5,802−6.5% | Reduced |
| International Biotechnology Trust PLC | 86,575 | $1.99M | 0.56% | +48,575+127.8% | Added |
| State of Wisconsin Investment Board | 87,826 | $2.02M | 0.01% | +1,260+1.5% | Added |
| TCW Group Inc | 88,311 | $2.03M | 0.03% | +49,280+126.3% | Added |
| TD Asset Management Inc | 88,322 | $2.03M | 0.00% | −10,887−11.0% | Reduced |
| Alps Advisors Inc | 90,045 | $2.07M | 0.02% | −1,984−2.2% | Reduced |
| Susquehanna Fundamental Investments, LLC | 91,249 | $2.10M | 0.05% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 91,806 | $2.12M | 0.02% | +86,966+1,796.8% | Added |
| Northwest & Ethical Investments L.P. | 92,497 | $2.13M | 0.07% | −2,366−2.5% | Reduced |
| Jump Financial, LLC | 93,371 | $2.15M | 0.09% | +93,371 | New |
| Legal & General Group Plc | 97,618 | $2.25M | 0.00% | +2,603+2.7% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $2.30M | 0.05% | 00.0% | Unchanged |
| Woodline Partners LP | 100,311 | $2.31M | 0.03% | +100,311 | New |
| Manufacturers Life Insurance Company, The | 115,183 | $2.65M | 0.00% | +3,124+2.8% | Added |
| Jane Street Group, LLC | 115,805 | $2.67M | 0.00% | +100,836+673.6% | Added |
| Two Sigma Advisers, LP | 117,900 | $2.72M | 0.01% | −33,900−22.3% | Reduced |
| California State Teachers Retirement System | 124,012 | $2.86M | 0.00% | +5,431+4.6% | Added |
| Wells Fargo & Company | 125,070 | $2.88M | 0.00% | +60,381+93.3% | Added |
| UBS Group AG | 127,351 | $2.93M | 0.00% | +7,170+6.0% | Added |
| Deutsche Bank AG | 130,729 | $3.01M | 0.00% | +19,999+18.1% | Added |
| New York State Common Retirement Fund | 134,894 | $3.11M | 0.00% | −16,060−10.6% | Reduced |
| BNP Paribas Arbitrage, SA | 138,072 | $3.18M | 0.01% | +80,384+139.3% | Added |
| Ensign Peak Advisors, Inc | 144,547 | $3.33M | 0.01% | +2,000+1.4% | Added |
| JPMorgan Chase & Co | 145,987 | $3.36M | 0.00% | −37,989−20.6% | Reduced |
| Rhumbline Advisers | 146,142 | $3.37M | 0.00% | +3,210+2.2% | Added |
| Twinbeech Capital LP | 149,302 | $3.44M | 0.07% | +149,302 | New |
| Alliancebernstein L.P. | 170,160 | $3.92M | 0.00% | +15,200+9.8% | Added |
| California Public Employees Retirement System | 176,131 | $4.06M | 0.00% | −17,430−9.0% | Reduced |
| Voya Investment Management LLC | 191,728 | $4.42M | 0.00% | +21,854+12.9% | Added |
| Swiss National Bank | 205,200 | $4.73M | 0.00% | −3,300−1.6% | Reduced |
| Citigroup Inc | 208,340 | $4.80M | 0.01% | +80,220+62.6% | Added |
| Teachers Retirement System of the State of Kentucky | 221,500 | $5.10M | 0.05% | +15,000+7.3% | Added |
| Walleye Trading LLC | 226,753 | $5.22M | 0.19% | +226,753 | New |
| Squarepoint Ops LLC | 235,662 | $5.43M | 0.04% | +235,662 | New |
| Sectoral Asset Management Inc | 244,850 | $5.64M | 1.08% | +1,000+0.4% | Added |
| Rafferty Asset Management, LLC | 256,973 | $5.92M | 0.04% | −26,769−9.4% | Reduced |
| Jefferies Financial Group Inc. | 263,123 | $6.06M | 0.13% | +263,123 | New |
| AXA S.A. | 289,242 | $6.66M | 0.02% | −678−0.2% | Reduced |
| Clarius Group, LLC | 290,330 | $6.69M | 0.57% | +29,726+11.4% | Added |
| Eagle Asset Management Inc | 302,961 | $6.98M | 0.04% | −26,123−7.9% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 304,630 | $7.02M | 0.02% | +2,760+0.9% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 306,970 | $7.07M | 0.05% | −2,122−0.7% | Reduced |
| Eventide Asset Management, LLC | 313,407 | $7.22M | 0.13% | +313,407 | New |
| Tekla Capital Management LLC | 324,829 | $7.48M | 0.28% | +52,309+19.2% | Added |
| Candriam Luxembourg S.C.A. | 357,878 | $7.59M | 0.05% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 340,564 | $7.85M | 0.01% | +317,311+1,364.6% | Added |
| Marshall Wace, LLP | 350,539 | $8.08M | 0.02% | −610,100−63.5% | Reduced |
| Nuveen Asset Management, LLC | 360,636 | $8.31M | 0.00% | −15,111−4.0% | Reduced |
| Millennium Management LLC | 386,289 | $8.90M | 0.01% | +89,196+30.0% | Added |
| Renaissance Technologies LLC | 408,100 | $9.40M | 0.01% | +158,500+63.5% | Added |
| Bank of America Corp | 419,836 | $9.67M | 0.00% | +85,064+25.4% | Added |
| Artisan Partners Limited Partnership | 423,665 | $9.76M | 0.02% | −12,008−2.8% | Reduced |
| American Century Companies Inc | 473,783 | $10.9M | 0.01% | +1,495+0.3% | Added |
| Principal Financial Group Inc | 488,961 | $11.3M | 0.01% | −37,498−7.1% | Reduced |
| Polar Capital Holdings Plc | 505,000 | $11.6M | 0.09% | +505,000 | New |
| Wasatch Advisors Inc | 558,167 | $12.9M | 0.08% | +107,217+23.8% | Added |
| UBS Asset Management Americas Inc | 567,141 | $13.1M | 0.01% | +23,218+4.3% | Added |
| Morgan Stanley | 569,122 | $13.1M | 0.00% | +136,636+31.6% | Added |
| Goldman Sachs Group Inc | 572,843 | $13.2M | 0.00% | −198,609−25.7% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 594,989 | $13.7M | 0.31% | −205,011−25.6% | Reduced |
| Cercano Management LLC | 625,000 | $14.4M | 0.57% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 627,325 | $14.4M | 0.00% | +69,067+12.4% | Added |
| T. Rowe Price Investment Management, Inc. | 647,013 | $14.9M | 0.01% | +13,655+2.2% | Added |
| Barclays PLC | 656,427 | $15.1M | 0.02% | +70,462+12.0% | Added |
| Artal Group S.A. | 802,899 | $18.5M | 1.10% | +2,899+0.4% | Added |
| Charles Schwab Investment Management Inc | 836,328 | $19.3M | 0.01% | −3450.0% | Reduced |
| Norges Bank | 969,440 | $22.3M | 0.00% | −54,766−5.3% | Reduced |
| Yiheng Capital Management, L.P. | 1,014,684 | $23.4M | 1.82% | 00.0% | Unchanged |
| Northern Trust Corp | 1,018,004 | $23.5M | 0.00% | +33,813+3.4% | Added |
| Federated Hermes, Inc. | 1,063,500 | $24.5M | 0.06% | +288,500+37.2% | Added |
| Baker Bros. Advisors LP | 1,088,738 | $25.1M | 0.14% | 00.0% | Unchanged |
| FMR LLC | 1,093,564 | $25.2M | 0.00% | −1,120,230−50.6% | Reduced |
| Pictet Asset Management SA | 1,248,490 | $28.8M | 0.04% | +77,134+6.6% | Added |
| Casdin Capital, LLC | 1,300,000 | $30.0M | 2.47% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,374,325 | $31.7M | 0.03% | +1,339,712+3,870.5% | Added |
| Credit Suisse AG | 1,553,472 | $35.8M | 0.04% | +20,089+1.3% | Added |
| Gilder Gagnon Howe & Co LLC | 1,656,397 | $38.2M | 0.63% | −110,745−6.3% | Reduced |
| Bank of New York Mellon Corp | 2,016,623 | $46.5M | 0.01% | +10,703+0.5% | Added |
| Geode Capital Management, LLC | 2,146,172 | $49.4M | 0.01% | +96,215+4.7% | Added |
| Capital Research Global Investors | 2,468,824 | $56.9M | 0.02% | +208,182+9.2% | Added |
| ARCH Venture Management, LLC | 2,568,749 | $59.2M | 28.57% | −1,100,000−30.0% | Reduced |
| Flagship Pioneering Inc. | 2,619,968 | $60.4M | 2.35% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 3,537,778 | $81.5M | 0.01% | −111,110−3.0% | Reduced |
| State Street Corp | 4,591,389 | $105.8M | 0.01% | −254,421−5.3% | Reduced |
| Wellington Management Group LLP | 5,200,460 | $119.8M | 0.02% | +78,730+1.5% | Added |
| Crestline Management, LP | 6,410,732 | $147.7M | 18.05% | −450,000−6.6% | Reduced |
| Temasek Holdings (Private) Ltd | 6,895,992 | $158.9M | 0.94% | +379,951+5.8% | Added |
| BlackRock Inc. | 9,474,397 | $218.3M | 0.01% | +152,383+1.6% | Added |