Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 199
- −1 vs. Q3 2022
- Shares held
- 105.9M
- +13.5M (+14.6%) vs. Q3 2022
- Total value
- $2.94B
- +$108.6M (+3.8%) vs. Q3 2022
- New holders
- 27
- 86 more added
- Sold out
- 28
- 53 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Board of Administration of Florida Retirement System | 32,288 | $897.9K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 33,700 | $937.0K | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 34,613 | $962.6K | 0.00% | −28,924−45.5% | Reduced |
| Pier 88 Investment Partners LLC | 35,240 | $980.0K | 0.24% | +23,150+191.5% | Added |
| International Biotechnology Trust PLC | 38,000 | $1.06M | 0.33% | 00.0% | Unchanged |
| TCW Group Inc | 39,031 | $1.09M | 0.02% | +39,031 | New |
| Envestnet Asset Management Inc | 40,917 | $1.14M | 0.00% | −599−1.4% | Reduced |
| ClariVest Asset Management LLC | 49,228 | $1.37M | 0.07% | −152−0.3% | Reduced |
| Tudor Investment Corp Et Al | 49,931 | $1.39M | 0.03% | +49,931 | New |
| American International Group, Inc. | 51,484 | $1.43M | 0.01% | +4,707+10.1% | Added |
| Mirae Asset Global Investments Co., Ltd. | 54,607 | $1.52M | 0.00% | +5,709+11.7% | Added |
| Platinum Investment Management Ltd | 55,341 | $1.54M | 0.06% | +4,370+8.6% | Added |
| MetLife Investment Management | 57,027 | $1.59M | 0.01% | +4,600+8.8% | Added |
| BNP Paribas Arbitrage, SA | 57,688 | $1.60M | 0.00% | −50,881−46.9% | Reduced |
| DekaBank Deutsche Girozentrale | 59,800 | $1.67M | 0.00% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 61,096 | $1.70M | 0.01% | −51,436−45.7% | Reduced |
| Point72 Asset Management, L.P. | 64,400 | $1.79M | 0.01% | −568,600−89.8% | Reduced |
| Wells Fargo & Company | 64,689 | $1.80M | 0.00% | −198−0.3% | Reduced |
| Guggenheim Capital LLC | 64,691 | $1.80M | 0.02% | +14,256+28.3% | Added |
| Two Sigma Investments, LP | 74,435 | $2.07M | 0.01% | −186,735−71.5% | Reduced |
| State of New Jersey Common Pension Fund D | 78,253 | $2.18M | 0.01% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 86,566 | $2.41M | 0.01% | −990−1.1% | Reduced |
| Invesco Ltd. | 88,739 | $2.47M | 0.00% | +10,844+13.9% | Added |
| Susquehanna Fundamental Investments, LLC | 91,249 | $2.54M | 0.04% | +91,249 | New |
| Alps Advisors Inc | 92,029 | $2.56M | 0.02% | +24,706+36.7% | Added |
| Northwest & Ethical Investments L.P. | 94,863 | $2.64M | 0.09% | +14,983+18.8% | Added |
| Legal & General Group Plc | 95,015 | $2.64M | 0.00% | +8,998+10.5% | Added |
| TD Asset Management Inc | 99,209 | $2.76M | 0.00% | +5,086+5.4% | Added |
| Russell Investments Group, Ltd. | 99,373 | $2.76M | 0.01% | −7,488−7.0% | Reduced |
| Edmond de Rothschild Holding S.A. | 99,880 | $2.78M | 0.07% | 00.0% | Unchanged |
| Deutsche Bank AG | 110,730 | $3.08M | 0.00% | +9,880+9.8% | Added |
| Manufacturers Life Insurance Company, The | 112,059 | $3.14M | 0.00% | +1,802+1.6% | Added |
| California State Teachers Retirement System | 118,581 | $3.30M | 0.01% | +5,618+5.0% | Added |
| UBS Group AG | 120,181 | $3.34M | 0.00% | +77,727+183.1% | Added |
| Citigroup Inc | 128,120 | $3.56M | 0.01% | −64,522−33.5% | Reduced |
| D. E. Shaw & Co., Inc. | 134,427 | $3.74M | 0.01% | +134,427 | New |
| Ensign Peak Advisors, Inc | 142,547 | $3.96M | 0.01% | +19,900+16.2% | Added |
| Man Group plc | 142,929 | $3.97M | 0.01% | +108,508+315.2% | Added |
| Rhumbline Advisers | 142,932 | $3.98M | 0.01% | +14,999+11.7% | Added |
| New York State Common Retirement Fund | 150,954 | $4.20M | 0.01% | +6,049+4.2% | Added |
| Two Sigma Advisers, LP | 151,800 | $4.22M | 0.01% | −32,000−17.4% | Reduced |
| Alliancebernstein L.P. | 154,960 | $4.31M | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 169,874 | $4.72M | 0.01% | +3,938+2.4% | Added |
| JPMorgan Chase & Co | 183,976 | $5.12M | 0.00% | +75,622+69.8% | Added |
| California Public Employees Retirement System | 193,561 | $5.38M | 0.00% | −6,294−3.1% | Reduced |
| Teachers Retirement System of the State of Kentucky | 206,500 | $5.74M | 0.06% | +29,304+16.5% | Added |
| Swiss National Bank | 208,500 | $5.80M | 0.00% | +4,400+2.2% | Added |
| Sectoral Asset Management Inc | 243,850 | $6.78M | 1.31% | +500+0.2% | Added |
| Renaissance Technologies LLC | 249,600 | $6.94M | 0.01% | −142,600−36.4% | Reduced |
| Clarius Group, LLC | 260,604 | $7.25M | 0.65% | 00.0% | Unchanged |
| Bamco Inc | 264,256 | $7.35M | 0.02% | −10,606−3.9% | Reduced |
| Tekla Capital Management LLC | 272,520 | $7.58M | 0.29% | +50,100+22.5% | Added |
| Rafferty Asset Management, LLC | 283,742 | $7.89M | 0.07% | +76,374+36.8% | Added |
| AXA S.A. | 289,920 | $8.06M | 0.03% | +41,148+16.5% | Added |
| Millennium Management LLC | 297,093 | $8.26M | 0.01% | −199,091−40.1% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 301,870 | $8.40M | 0.02% | −5,590−1.8% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 309,092 | $8.60M | 0.06% | +17,784+6.1% | Added |
| Eagle Asset Management Inc | 329,084 | $9.09M | 0.06% | +73,624+28.8% | Added |
| Bank of America Corp | 334,772 | $9.31M | 0.00% | +114,555+52.0% | Added |
| Candriam Luxembourg S.C.A. | 357,878 | $9.95M | 0.07% | 00.0% | Unchanged |
| Nuveen Asset Management, LLC | 375,747 | $10.4M | 0.00% | +24,288+6.9% | Added |
| Morgan Stanley | 432,486 | $12.0M | 0.00% | −248,846−36.5% | Reduced |
| Artisan Partners Limited Partnership | 435,673 | $12.1M | 0.02% | −7,428−1.7% | Reduced |
| Wasatch Advisors Inc | 450,950 | $12.5M | 0.08% | +91,477+25.4% | Added |
| American Century Companies Inc | 472,288 | $13.1M | 0.01% | −860.0% | Reduced |
| Principal Financial Group Inc | 526,459 | $14.6M | 0.01% | −19,412−3.6% | Reduced |
| UBS Asset Management Americas Inc | 543,923 | $15.1M | 0.01% | +13,719+2.6% | Added |
| Dimensional Fund Advisors LP | 558,258 | $15.5M | 0.01% | −51,581−8.5% | Reduced |
| Barclays PLC | 585,965 | $16.3M | 0.01% | +260,498+80.0% | Added |
| Cercano Management LLC | 625,000 | $17.4M | 0.71% | +625,000 | New |
| T. Rowe Price Investment Management, Inc. | 633,358 | $17.6M | 0.01% | +211,001+50.0% | Added |
| Goldman Sachs Group Inc | 771,452 | $21.5M | 0.01% | +43,180+5.9% | Added |
| Federated Hermes, Inc. | 775,000 | $21.6M | 0.06% | +118,407+18.0% | Added |
| Artal Group S.A. | 800,000 | $22.2M | 1.28% | +200,000+33.3% | Added |
| Deerfield Management Company, L.P. (Series C) | 800,000 | $22.2M | 0.46% | +800,000 | New |
| Charles Schwab Investment Management Inc | 836,673 | $23.3M | 0.01% | +105,793+14.5% | Added |
| Marshall Wace, LLP | 960,639 | $26.7M | 0.07% | +284,769+42.1% | Added |
| Northern Trust Corp | 984,191 | $27.4M | 0.01% | +94,223+10.6% | Added |
| Yiheng Capital Management, L.P. | 1,014,684 | $28.2M | 2.19% | 00.0% | Unchanged |
| Norges Bank | 1,024,206 | $28.5M | 0.01% | +80,802+8.6% | Added |
| Baker Bros. Advisors LP | 1,088,738 | $30.3M | 0.18% | +500,000+84.9% | Added |
| Pictet Asset Management SA | 1,171,356 | $32.6M | 0.05% | +168,171+16.8% | Added |
| Casdin Capital, LLC | 1,300,000 | $36.2M | 2.82% | +305,000+30.7% | Added |
| Credit Suisse AG | 1,533,383 | $42.6M | 0.05% | −78,046−4.8% | Reduced |
| Gilder Gagnon Howe & Co LLC | 1,767,142 | $49.1M | 0.92% | −96,135−5.2% | Reduced |
| Bank of New York Mellon Corp | 2,005,920 | $55.8M | 0.01% | +110,628+5.8% | Added |
| Geode Capital Management, LLC | 2,049,957 | $57.0M | 0.01% | +273,793+15.4% | Added |
| FMR LLC | 2,213,794 | $61.6M | 0.01% | −238,662−9.7% | Reduced |
| Capital Research Global Investors | 2,260,642 | $62.9M | 0.02% | +2,172,875+2,475.7% | Added |
| Flagship Pioneering Inc. | 2,619,968 | $72.9M | 2.33% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 3,648,888 | $101.5M | 0.02% | +170,520+4.9% | Added |
| ARCH Venture Management, LLC | 3,668,749 | $102.0M | 26.13% | 00.0% | Unchanged |
| State Street Corp | 4,845,810 | $134.8M | 0.01% | +653,582+15.6% | Added |
| Wellington Management Group LLP | 5,121,730 | $142.4M | 0.03% | +5,100,036+23,509.0% | Added |
| Temasek Holdings (Private) Ltd | 6,516,041 | $181.2M | 1.06% | +940,000+16.9% | Added |
| Crestline Management, LP | 6,860,732 | $190.8M | 27.96% | −300,000−4.2% | Reduced |
| BlackRock Inc. | 9,322,014 | $259.2M | 0.01% | +723,802+8.4% | Added |
| Vanguard Group Inc | 9,947,098 | $276.6M | 0.01% | +1,545,067+18.4% | Added |
| Baillie Gifford & Co | 15,119,474 | $420.5M | 0.44% | +404,423+2.7% | Added |
| Woodline Partners LP | 0 | $0 | 0.00% | −444,256−100.0% | Sold out |