Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q2 2022
Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 188
- +2 vs. Q1 2022
- Shares held
- 92.7M
- +6.15M (+7.1%) vs. Q1 2022
- Total value
- $2.73B
- −$55.8M (−2.0%) vs. Q1 2022
- New holders
- 21
- 72 more added
- Sold out
- 19
- 58 more reduced
4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| PDT Partners, LLC | 36,341 | $1.07M | 0.09% | +18,491+103.6% | Added |
| AIA Group Ltd | 37,064 | $1.09M | 0.06% | −4,321−10.4% | Reduced |
| SG Americas Securities, LLC | 39,316 | $1.16M | 0.02% | +30,336+337.8% | Added |
| Los Angeles Capital Management LLC | 43,919 | $1.29M | 0.01% | +1,667+3.9% | Added |
| American International Group, Inc. | 46,116 | $1.36M | 0.01% | +945+2.1% | Added |
| Voloridge Investment Management, LLC | 48,058 | $1.41M | 0.01% | +10,669+28.5% | Added |
| MetLife Investment Management | 50,392 | $1.48M | 0.01% | 00.0% | Unchanged |
| Platinum Investment Management Ltd | 50,971 | $1.50M | 0.06% | 00.0% | Unchanged |
| ClariVest Asset Management LLC | 54,638 | $1.61M | 0.07% | −11,000−16.8% | Reduced |
| DekaBank Deutsche Girozentrale | 59,800 | $1.71M | 0.00% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 61,007 | $1.79M | 0.01% | +6,580+12.1% | Added |
| ExodusPoint Capital Management, LP | 64,187 | $1.89M | 0.03% | +64,187 | New |
| Putnam Investments LLC | 64,276 | $1.89M | 0.00% | +333+0.5% | Added |
| Two Sigma Investments, LP | 64,324 | $1.89M | 0.01% | +34,323+114.4% | Added |
| Natixis | 69,030 | $2.03M | 0.01% | −167,658−70.8% | Reduced |
| Wells Fargo & Company | 69,206 | $2.04M | 0.00% | −41,062−37.2% | Reduced |
| Cubist Systematic Strategies, LLC | 71,904 | $2.12M | 0.02% | +55,735+344.7% | Added |
| Alps Advisors Inc | 72,940 | $2.15M | 0.02% | +72,940 | New |
| Invesco Ltd. | 73,666 | $2.17M | 0.00% | +6,032+8.9% | Added |
| Northwest & Ethical Investments L.P. | 79,880 | $2.35M | 0.09% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 85,672 | $2.52M | 0.01% | −18,904−18.1% | Reduced |
| D. E. Shaw & Co., Inc. | 86,113 | $2.53M | 0.00% | +79,865+1,278.2% | Added |
| Legal & General Group Plc | 86,503 | $2.55M | 0.00% | +7,077+8.9% | Added |
| State of Wisconsin Investment Board | 87,139 | $2.56M | 0.01% | −34,661−28.5% | Reduced |
| Russell Investments Group, Ltd. | 88,230 | $2.60M | 0.01% | +36,710+71.3% | Added |
| State of New Jersey Common Pension Fund D | 91,898 | $2.71M | 0.01% | +14,967+19.5% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $2.94M | 0.07% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 100,025 | $2.94M | 0.00% | +2,653+2.7% | Added |
| Rafferty Asset Management, LLC | 101,471 | $2.99M | 0.03% | −74,491−42.3% | Reduced |
| Deutsche Bank AG | 110,297 | $3.25M | 0.00% | −2,617−2.3% | Reduced |
| Citigroup Inc | 111,814 | $3.29M | 0.00% | +76,430+216.0% | Added |
| California State Teachers Retirement System | 114,884 | $3.38M | 0.01% | +8,291+7.8% | Added |
| Rhumbline Advisers | 117,475 | $3.46M | 0.01% | +20,330+20.9% | Added |
| Bank of America Corp | 119,067 | $3.50M | 0.00% | −122,168−50.6% | Reduced |
| Manufacturers Life Insurance Company, The | 120,287 | $3.50M | 0.00% | +2,202+1.9% | Added |
| TD Asset Management Inc | 121,223 | $3.57M | 0.00% | −11,814−8.9% | Reduced |
| New York State Common Retirement Fund | 140,829 | $4.14M | 0.01% | +5,988+4.4% | Added |
| Alliancebernstein L.P. | 154,960 | $4.56M | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 160,500 | $4.72M | 0.01% | −11,700−6.8% | Reduced |
| Woodline Partners LP | 180,972 | $5.33M | 0.09% | −75,706−29.5% | Reduced |
| Swiss National Bank | 201,400 | $5.93M | 0.00% | +13,700+7.3% | Added |
| Sectoral Asset Management Inc | 202,100 | $5.95M | 1.20% | −5,000−2.4% | Reduced |
| California Public Employees Retirement System | 202,177 | $5.95M | 0.01% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 212,823 | $6.26M | 0.05% | +74,324+53.7% | Added |
| Tekla Capital Management LLC | 222,420 | $6.55M | 0.26% | 00.0% | Unchanged |
| Voya Investment Management LLC | 230,830 | $6.79M | 0.02% | +99,848+76.2% | Added |
| AXA S.A. | 247,691 | $7.29M | 0.03% | +47,123+23.5% | Added |
| Renaissance Technologies LLC | 253,500 | $7.46M | 0.01% | +130,900+106.8% | Added |
| Eagle Asset Management Inc | 263,704 | $7.76M | 0.05% | +59,854+29.4% | Added |
| Principal Financial Group Inc | 267,732 | $7.88M | 0.01% | −1,272−0.5% | Reduced |
| Bamco Inc | 275,705 | $8.11M | 0.03% | −379,643−57.9% | Reduced |
| Citadel Advisors LLC | 306,002 | $9.01M | 0.01% | −445,601−59.3% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 314,890 | $9.27M | 0.02% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 322,882 | $9.50M | 0.08% | +181,375+128.2% | Added |
| Wasatch Advisors Inc | 341,674 | $10.1M | 0.06% | +104,251+43.9% | Added |
| Nuveen Asset Management, LLC | 360,158 | $10.6M | 0.00% | −10,071−2.7% | Reduced |
| Barclays PLC | 368,771 | $10.9M | 0.01% | +310,639+534.4% | Added |
| Goldman Sachs Group Inc | 420,742 | $12.4M | 0.00% | +14,514+3.6% | Added |
| Morgan Stanley | 423,011 | $12.4M | 0.00% | −282,644−40.1% | Reduced |
| Artisan Partners Limited Partnership | 450,689 | $13.3M | 0.02% | −73,442−14.0% | Reduced |
| American Century Companies Inc | 469,281 | $13.8M | 0.01% | −67,190−12.5% | Reduced |
| UBS Asset Management Americas Inc | 487,405 | $14.3M | 0.01% | +52,578+12.1% | Added |
| Baker Bros. Advisors LP | 588,738 | $17.3M | 0.10% | +500,000+563.5% | Added |
| Artal Group S.A. | 600,000 | $17.7M | 0.98% | 00.0% | Unchanged |
| Millennium Management LLC | 645,336 | $19.0M | 0.02% | +645,336 | New |
| Federated Hermes, Inc. | 668,929 | $19.7M | 0.05% | −236,316−26.1% | Reduced |
| Charles Schwab Investment Management Inc | 731,522 | $21.5M | 0.01% | +27,271+3.9% | Added |
| Marshall Wace, LLP | 817,650 | $24.1M | 0.05% | +664,795+434.9% | Added |
| Norges Bank | 831,809 | $24.5M | 0.01% | −14,254−1.7% | Reduced |
| Northern Trust Corp | 890,618 | $26.2M | 0.01% | −15,610−1.7% | Reduced |
| Dimensional Fund Advisors LP | 891,678 | $26.2M | 0.01% | +13,454+1.5% | Added |
| Yiheng Capital Management, L.P. | 1,014,684 | $29.9M | 2.14% | 00.0% | Unchanged |
| Pictet Asset Management SA | 1,015,158 | $29.9M | 0.04% | −8,405−0.8% | Reduced |
| Casdin Capital, LLC | 1,500,000 | $44.1M | 3.73% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 1,706,581 | $50.2M | 0.01% | +75,634+4.6% | Added |
| Bank of New York Mellon Corp | 1,868,130 | $55.0M | 0.01% | +258,913+16.1% | Added |
| Gilder Gagnon Howe & Co LLC | 1,956,820 | $57.6M | 1.03% | −662,397−25.3% | Reduced |
| Credit Suisse AG | 1,960,025 | $57.7M | 0.06% | +1,451+0.1% | Added |
| Flagship Pioneering Inc. | 2,619,968 | $77.1M | 2.90% | 00.0% | Unchanged |
| FMR LLC | 2,869,740 | $84.5M | 0.01% | −74,315−2.5% | Reduced |
| State Street Corp | 3,750,700 | $110.4M | 0.01% | −76,092−2.0% | Reduced |
| Price T Rowe Associates Inc | 4,610,177 | $135.7M | 0.02% | −313,248−6.4% | Reduced |
| ARCH Venture Management, LLC | 5,168,749 | $152.1M | 18.54% | +5,168,749 | New |
| Temasek Holdings (Private) Ltd | 5,369,487 | $158.0M | 0.87% | 00.0% | Unchanged |
| Crestline Management, LP | 7,460,732 | $219.6M | 28.78% | 00.0% | Unchanged |
| Vanguard Group Inc | 8,302,501 | $244.3M | 0.01% | +190,471+2.3% | Added |
| BlackRock Inc. | 8,784,632 | $258.5M | 0.01% | +598,892+7.3% | Added |
| Baillie Gifford & Co | 14,869,374 | $437.6M | 0.45% | −111,058−0.7% | Reduced |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −34,435−100.0% | Sold out |
| Duality Advisers, LP | 0 | $0 | 0.00% | −34,200−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −28,296−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −26,000−100.0% | Sold out |
| Eaton Vance Management | 0 | $0 | 0.00% | −23,057−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −22,686−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −18,046−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −15,203−100.0% | Sold out |
| First Trust Advisors LP | 0 | $0 | 0.00% | −14,224−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −13,443−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −6,940−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −6,693−100.0% | Sold out |