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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
188
+2 vs. Q1 2022
Shares held
92.7M
+6.15M (+7.1%) vs. Q1 2022
Total value
$2.73B
−$55.8M (−2.0%) vs. Q1 2022
New holders
21
72 more added
Sold out
19
58 more reduced

4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 188 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2022: $2.73B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2022.

Institutions holding DNLI in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
State of Wyoming8$00.00%−1,126−99.3%Reduced
Covestor Ltd13$00.00%−245−95.0%Reduced
Signaturefd, LLC5$00.00%−48−90.6%Reduced
Central Trust Co4$00.00%00.0%Unchanged
Toronto Dominion Bank2$00.00%00.0%Unchanged
Institutional & Family Asset Management, LLC6$00.00%00.0%Unchanged
Parallel Advisors, LLC10$00.00%+8+400.0%Added
Global Retirement Partners, LLC3$00.00%00.0%Unchanged
Allworth Financial LP8$00.00%+8New
Asset Management One Co.,Ltd.100$2.00K0.00%00.0%Unchanged
Farmers & Merchants Investments Inc58$2.00K0.00%00.0%Unchanged
CWM, LLC69$2.00K0.00%+69New
Bell Investment Advisors, Inc64$2.00K0.00%+64New
TCI Wealth Advisors, Inc.114$3.00K0.00%−182−61.5%Reduced
Your Advocates Ltd., LLP100$3.00K0.00%00.0%Unchanged
Hoey Investments, Inc100$3.00K0.00%+100New
Leonteq Securities AG103$3.03K0.00%−34−24.8%Reduced
Captrust Financial Advisors146$4.00K0.00%−25−14.6%Reduced
Huntington National Bank138$4.00K0.00%00.0%Unchanged
Activest Wealth Management131$4.00K0.00%00.0%Unchanged
Private Capital Group, LLC176$5.00K0.00%−16−8.3%Reduced
First Horizon Advisors, Inc.215$6.00K0.00%+200+1,333.3%Added
City State Bank250$7.00K0.00%00.0%Unchanged
Lindbrook Capital, LLC223$7.00K0.00%+19+9.3%Added
US Bancorp457$13.0K0.00%−102−18.2%Reduced
Umb Bank N A444$13.0K0.00%00.0%Unchanged
Daiwa Securities Group Inc.458$13.0K0.00%+102+28.7%Added
Cutler Group LP680$20.0K0.00%−620−47.7%Reduced
Quantbot Technologies LP800$23.0K0.00%+633+379.0%Added
Patriot Financial Group Insurance Agency, LLC800$24.0K0.00%−110−12.1%Reduced
The PNC Financial Services Group, Inc.818$24.0K0.00%−20−2.4%Reduced
International Biotechnology Trust PLC1,118$38.0K0.75%−36,882−97.1%Reduced
Macquarie Group Ltd1,411$42.0K0.00%00.0%Unchanged
Brown Brothers Harriman & Co1,524$45.0K0.00%−500−24.7%Reduced
Exchange Traded Concepts, LLC1,874$55.0K0.00%+1,382+280.9%Added
Itau Unibanco Holding S.A.1,951$57.0K0.00%+3+0.2%Added
High Net Worth Advisory Group LLC2,000$59.0K0.02%00.0%Unchanged
Advisor Group Holdings, Inc.2,264$66.0K0.00%−53−2.3%Reduced
Allspring Global Investments Holdings, LLC2,308$67.0K0.00%−37,909−94.3%Reduced
Levin Capital Strategies, L.P.2,500$74.0K0.01%+2,500New
Amundi3,017$102.0K0.00%00.0%Unchanged
Group One Trading, L.P.3,522$104.0K0.00%−3,437−49.4%Reduced
Great West Life Assurance Co4,642$137.0K0.00%+768+19.8%Added
Virtus ETF Advisers LLC4,839$142.0K0.05%+1,406+41.0%Added
Lazard Asset Management LLC5,353$157.0K0.00%+5,353New
Metropolitan Life Insurance Co5,945$175.0K0.01%+366+6.6%Added
UBS Group AG6,375$188.0K0.00%−32,737−83.7%Reduced
Mackenzie Financial Corp6,898$203.0K0.00%+6,898New
Creative Planning7,075$208.0K0.00%+295+4.4%Added
Ameritas Investment Partners, Inc.7,469$219.0K0.01%+335+4.7%Added
Prudential Financial Inc8,235$238.0K0.00%−12,518−60.3%Reduced
GAM Holding AG8,403$247.0K0.02%00.0%Unchanged
Bridgewater Associates, LP8,660$255.0K0.00%+1,793+26.1%Added
Fred Alger Management, LLC8,983$264.0K0.00%+8,983New
Brandywine Managers, LLC9,601$283.0K0.69%00.0%Unchanged
SEI Investments Co10,358$305.0K0.00%−160−1.5%Reduced
Tower Research Capital LLC (TRC)10,516$309.0K0.01%+8,419+401.5%Added
Susquehanna International Group, LLP10,526$310.0K0.00%−75,192−87.7%Reduced
Occudo Quantitative Strategies LP10,672$314.0K0.03%+10,672New
Victory Capital Management Inc10,883$320.0K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.11,230$330.0K0.00%−8,422−42.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)11,508$339.0K0.00%+118+1.0%Added
Utah Retirement Systems11,600$341.0K0.01%00.0%Unchanged
E Fund Management Co., Ltd.11,641$343.0K0.03%+2,814+31.9%Added
Public Employees Retirement Association of Colorado12,238$360.0K0.00%00.0%Unchanged
Arthur M. Cohen & Associates, LLC12,416$365.0K0.09%00.0%Unchanged
Profund Advisors LLC12,776$376.0K0.02%−1,478−10.4%Reduced
Stifel Financial Corp12,990$383.0K0.00%−650−4.8%Reduced
Pier 88 Investment Partners LLC13,080$385.0K0.09%+13,070+130,700.0%Added
AlphaCrest Capital Management LLC13,300$391.0K0.02%−13,900−51.1%Reduced
Dana Investment Advisors, Inc.13,350$393.0K0.02%+2,054+18.2%Added
Handelsbanken Fonder AB13,400$394.0K0.00%+1,600+13.6%Added
Royal Bank of Canada13,407$394.0K0.00%+5,026+60.0%Added
Teacher Retirement System of Texas13,879$408.0K0.00%−2,609−15.8%Reduced
Jane Street Group, LLC13,923$410.0K0.00%+13,923New
Jump Financial, LLC14,297$420.0K0.02%+14,297New
Allianz Asset Management GmbH14,820$436.0K0.00%−3,000−16.8%Reduced
Gotham Asset Management, LLC15,285$450.0K0.01%+15,285New
Amalgamated Bank15,562$458.0K0.00%+669+4.5%Added
Corton Capital Inc.15,973$470.0K0.44%+15,973New
Janus Henderson Group PLC16,068$472.0K0.00%−67,627−80.8%Reduced
Tudor Investment Corp Et Al16,464$485.0K0.01%+16,464New
Engineers Gate Manager LP17,320$510.0K0.02%+1,274+7.9%Added
Delphia (USA) Inc.17,586$518.0K0.36%+17,586New
Nisa Investment Advisors, LLC17,816$524.0K0.00%+15,200+581.0%Added
Bartlett & Co. Wealth Management LLC18,511$544.8K0.01%+10.0%Added
Bartlett & Co. LLC18,511$545.0K0.01%+10.0%Added
Ironwood Investment Management LLC19,856$584.0K0.39%+14+0.1%Added
ProShare Advisors LLC22,174$653.0K0.00%−9,707−30.4%Reduced
BNP Paribas Arbitrage, SA22,332$657.2K0.00%+14,089+170.9%Added
Arizona State Retirement System23,167$682.0K0.01%+1,709+8.0%Added
HRT Financial LP23,600$694.0K0.01%+23,600New
Mercer Global Advisors Inc23,863$702.0K0.00%+948+4.1%Added
Erste Asset Management GmbH26,900$779.6K0.02%00.0%Unchanged
Concentric Wealth Management, LLC27,967$823.0K0.28%00.0%Unchanged
Clarius Group, LLC28,519$839.0K0.08%+2,074+7.8%Added
Envestnet Asset Management Inc30,443$896.0K0.00%−2,915−8.7%Reduced
State Board of Administration of Florida Retirement System32,288$950.0K0.00%+1,820+6.0%Added
STRS Ohio33,700$991.0K0.00%+2,800+9.1%Added
Mirae Asset Global Investments Co., Ltd.35,234$1.04M0.00%+35,234New