Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 190
- −21 vs. Q4 2021
- Shares held
- 86.8M
- +1.55M (+1.8%) vs. Q4 2021
- Total value
- $2.79B
- −$1.01B (−26.6%) vs. Q4 2021
- New holders
- 19
- 68 more added
- Sold out
- 40
- 69 more reduced
2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| ProShare Advisors LLC | 31,881 | $1.03M | 0.00% | −7,521−19.1% | Reduced |
| Envestnet Asset Management Inc | 33,358 | $1.07M | 0.00% | +4,795+16.8% | Added |
| Duality Advisers, LP | 34,200 | $1.10M | 0.12% | +34,200 | New |
| Squarepoint Ops LLC | 34,435 | $1.11M | 0.01% | +34,435 | New |
| Citigroup Inc | 35,384 | $1.14M | 0.00% | −84,997−70.6% | Reduced |
| Clarius Group, LLC | 26,445 | $1.18M | 0.09% | 00.0% | Unchanged |
| Voloridge Investment Management, LLC | 37,389 | $1.20M | 0.01% | +23,448+168.2% | Added |
| UBS Group AG | 39,112 | $1.26M | 0.00% | −53,236−57.6% | Reduced |
| Allspring Global Investments Holdings, LLC | 40,217 | $1.29M | 0.00% | +1,605+4.2% | Added |
| AIA Group Ltd | 41,385 | $1.33M | 0.06% | −66,457−61.6% | Reduced |
| Los Angeles Capital Management LLC | 42,252 | $1.36M | 0.01% | +1,160+2.8% | Added |
| American International Group, Inc. | 45,171 | $1.45M | 0.01% | −3,179−6.6% | Reduced |
| MetLife Investment Management | 50,392 | $1.62M | 0.01% | +18,003+55.6% | Added |
| Platinum Investment Management Ltd | 50,971 | $1.64M | 0.05% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 51,520 | $1.66M | 0.00% | −14,601−22.1% | Reduced |
| Guggenheim Capital LLC | 54,427 | $1.75M | 0.01% | +7,445+15.8% | Added |
| Barclays PLC | 58,132 | $1.87M | 0.00% | −62,689−51.9% | Reduced |
| DekaBank Deutsche Girozentrale | 59,800 | $1.94M | 0.00% | +5,400+9.9% | Added |
| Putnam Investments LLC | 63,943 | $2.06M | 0.00% | −12,917−16.8% | Reduced |
| ClariVest Asset Management LLC | 65,638 | $2.11M | 0.08% | 00.0% | Unchanged |
| Invesco Ltd. | 67,634 | $2.18M | 0.00% | +23,170+52.1% | Added |
| State of New Jersey Common Pension Fund D | 76,931 | $2.48M | 0.01% | +17,313+29.0% | Added |
| Legal & General Group Plc | 79,426 | $2.56M | 0.00% | +455+0.6% | Added |
| Northwest & Ethical Investments L.P. | 79,880 | $2.57M | 0.08% | +48,280+152.8% | Added |
| Janus Henderson Group PLC | 83,695 | $2.69M | 0.00% | −16,768−16.7% | Reduced |
| Susquehanna International Group, LLP | 85,718 | $2.76M | 0.00% | −33,177−27.9% | Reduced |
| Baker Bros. Advisors LP | 88,738 | $2.85M | 0.02% | 00.0% | Unchanged |
| Rhumbline Advisers | 97,145 | $3.13M | 0.00% | +496+0.5% | Added |
| JPMorgan Chase & Co | 97,372 | $3.13M | 0.00% | +14,227+17.1% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $3.21M | 0.07% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 104,576 | $3.37M | 0.01% | +120+0.1% | Added |
| California State Teachers Retirement System | 106,593 | $3.43M | 0.00% | −9,922−8.5% | Reduced |
| Wells Fargo & Company | 110,268 | $3.55M | 0.00% | −33,268−23.2% | Reduced |
| Deutsche Bank AG | 112,914 | $3.63M | 0.00% | −5,418−4.6% | Reduced |
| Manufacturers Life Insurance Company, The | 118,085 | $3.82M | 0.00% | +71,589+154.0% | Added |
| State of Wisconsin Investment Board | 121,800 | $3.92M | 0.01% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 122,600 | $3.94M | 0.00% | +68,300+125.8% | Added |
| Voya Investment Management LLC | 130,982 | $4.21M | 0.01% | +95,909+273.5% | Added |
| TD Asset Management Inc | 133,037 | $4.28M | 0.00% | +10,700+8.7% | Added |
| New York State Common Retirement Fund | 134,841 | $4.34M | 0.00% | +540.0% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 138,499 | $4.46M | 0.03% | −640.0% | Reduced |
| Candriam Luxembourg S.C.A. | 141,507 | $4.55M | 0.03% | 00.0% | Unchanged |
| Marshall Wace, LLP | 152,855 | $4.92M | 0.01% | −231,089−60.2% | Reduced |
| Alliancebernstein L.P. | 154,960 | $4.99M | 0.00% | +300+0.2% | Added |
| Teachers Retirement System of the State of Kentucky | 171,496 | $5.52M | 0.05% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 172,200 | $5.54M | 0.01% | −97,400−36.1% | Reduced |
| Rafferty Asset Management, LLC | 175,962 | $5.66M | 0.03% | +54,207+44.5% | Added |
| Swiss National Bank | 187,700 | $6.04M | 0.00% | +14,000+8.1% | Added |
| AXA S.A. | 200,568 | $6.45M | 0.02% | −19,498−8.9% | Reduced |
| California Public Employees Retirement System | 202,177 | $6.50M | 0.01% | 00.0% | Unchanged |
| Eagle Asset Management Inc | 203,850 | $6.56M | 0.03% | +12,334+6.4% | Added |
| Sectoral Asset Management Inc | 207,100 | $6.66M | 1.18% | +17,500+9.2% | Added |
| Tekla Capital Management LLC | 222,420 | $7.16M | 0.25% | 00.0% | Unchanged |
| Natixis | 236,688 | $7.61M | 0.03% | −56,866−19.4% | Reduced |
| Wasatch Advisors Inc | 237,423 | $7.64M | 0.04% | +63,181+36.3% | Added |
| Bank of America Corp | 241,235 | $7.76M | 0.00% | +112,287+87.1% | Added |
| Woodline Partners LP | 256,678 | $8.26M | 0.14% | +204,224+389.3% | Added |
| Principal Financial Group Inc | 269,004 | $8.65M | 0.01% | −61,271−18.6% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 314,890 | $10.1M | 0.02% | +5,850+1.9% | Added |
| Nuveen Asset Management, LLC | 370,229 | $12.3M | 0.00% | −6,815−1.8% | Reduced |
| Goldman Sachs Group Inc | 406,228 | $13.1M | 0.00% | −4,536−1.1% | Reduced |
| UBS Asset Management Americas Inc | 434,827 | $14.0M | 0.01% | −5,209−1.2% | Reduced |
| Artisan Partners Limited Partnership | 524,131 | $16.9M | 0.02% | +2,723+0.5% | Added |
| American Century Companies Inc | 536,471 | $17.3M | 0.01% | +1890.0% | Added |
| Artal Group S.A. | 600,000 | $19.3M | 0.82% | 00.0% | Unchanged |
| Bamco Inc | 655,348 | $21.1M | 0.05% | −340,956−34.2% | Reduced |
| Charles Schwab Investment Management Inc | 704,251 | $22.7M | 0.01% | −12,939−1.8% | Reduced |
| Morgan Stanley | 705,655 | $22.7M | 0.00% | +418,397+145.7% | Added |
| Citadel Advisors LLC | 751,603 | $24.2M | 0.03% | +265,920+54.8% | Added |
| Norges Bank | 846,063 | $27.2M | 0.01% | −460.0% | Reduced |
| Dimensional Fund Advisors LP | 878,224 | $28.3M | 0.01% | +106,027+13.7% | Added |
| Federated Hermes, Inc. | 905,245 | $29.1M | 0.07% | +169,813+23.1% | Added |
| Northern Trust Corp | 906,228 | $29.2M | 0.01% | −52,861−5.5% | Reduced |
| Yiheng Capital Management, L.P. | 1,014,684 | $32.6M | 2.09% | +679,500+202.7% | Added |
| Pictet Asset Management SA | 1,023,563 | $32.9M | 0.04% | +24,943+2.5% | Added |
| Casdin Capital, LLC | 1,500,000 | $48.3M | 2.16% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 1,609,217 | $51.8M | 0.01% | +676,625+72.6% | Added |
| Geode Capital Management, LLC | 1,630,947 | $52.5M | 0.01% | +2,080+0.1% | Added |
| Credit Suisse AG | 1,958,574 | $63.0M | 0.05% | −5,074−0.3% | Reduced |
| Gilder Gagnon Howe & Co LLC | 2,619,217 | $84.3M | 0.78% | −280,897−9.7% | Reduced |
| Flagship Pioneering Inc. | 2,619,968 | $84.3M | 1.98% | 00.0% | Unchanged |
| FMR LLC | 2,944,055 | $94.7M | 0.01% | −7,736−0.3% | Reduced |
| State Street Corp | 3,826,792 | $123.1M | 0.01% | +799,221+26.4% | Added |
| Price T Rowe Associates Inc | 4,923,425 | $158.4M | 0.02% | +287,992+6.2% | Added |
| Temasek Holdings (Private) Ltd | 5,369,487 | $172.7M | 0.73% | 00.0% | Unchanged |
| Crestline Management, LP | 7,460,732 | $240.0M | 30.17% | −244,307−3.2% | Reduced |
| Vanguard Group Inc | 8,112,030 | $261.0M | 0.01% | −49,500−0.6% | Reduced |
| BlackRock Inc. | 8,185,740 | $263.3M | 0.01% | +74,918+0.9% | Added |
| Baillie Gifford & Co | 14,980,432 | $481.9M | 0.34% | −75,949−0.5% | Reduced |
| International Biotechnology Trust PLC | 38,000 | – | – | +12,000+46.2% | Added |
| Nomura Asset Management Co Ltd | 0 | $0 | 0.00% | −10,402−100.0% | Sold out |
| Jennison Associates LLC | 0 | $0 | 0.00% | −224,184−100.0% | Sold out |
| Goldstream Capital Management Ltd | 0 | $0 | 0.00% | −78,418−100.0% | Sold out |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −53,835−100.0% | Sold out |
| Jupiter Asset Management Ltd | 0 | $0 | 0.00% | −50,023−100.0% | Sold out |
| Mark Asset Management LP | 0 | $0 | 0.00% | −40,370−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −24,456−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −18,360−100.0% | Sold out |
| Vontobel Holding Ltd. | 0 | $0 | 0.00% | −17,988−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −12,874−100.0% | Sold out |