Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 213
- +2 vs. Q3 2021
- Shares held
- 85.3M
- +675.1K (+0.8%) vs. Q3 2021
- Total value
- $3.80B
- −$465.4M (−10.9%) vs. Q3 2021
- New holders
- 29
- 86 more added
- Sold out
- 27
- 62 more reduced
3 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vontobel Holding Ltd. | 17,988 | $810.0K | 0.01% | +3,988+28.5% | Added |
| Millennium Management LLC | 18,360 | $819.0K | 0.00% | −23,482−56.1% | Reduced |
| Ironwood Investment Management LLC | 19,383 | $864.0K | 0.43% | +290+1.5% | Added |
| BNP Paribas Arbitrage, SA | 19,699 | $878.6K | 0.00% | +1,700+9.4% | Added |
| Arizona State Retirement System | 21,280 | $949.0K | 0.01% | −178−0.8% | Reduced |
| Metropolitan Life Insurance Co | 24,089 | $1.07M | 0.01% | 00.0% | Unchanged |
| Jane Street Group, LLC | 24,456 | $1.09M | 0.00% | +5,759+30.8% | Added |
| Virginia Retirement Systems Et Al | 25,700 | $1.15M | 0.01% | −2,900−10.1% | Reduced |
| International Biotechnology Trust PLC | 26,000 | $1.16M | 0.26% | +26,000 | New |
| Clarius Group, LLC | 26,445 | $1.18M | 0.09% | +13,750+108.3% | Added |
| Concentric Wealth Management, LLC | 27,967 | $1.25M | 0.35% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 28,563 | $1.27M | 0.00% | +2,312+8.8% | Added |
| Erste Asset Management GmbH | 30,600 | $1.35M | 0.02% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 30,468 | $1.36M | 0.00% | +449+1.5% | Added |
| STRS Ohio | 30,900 | $1.38M | 0.00% | 00.0% | Unchanged |
| Northwest & Ethical Investments L.P. | 31,600 | $1.41M | 0.04% | +31,600 | New |
| MetLife Investment Management | 32,389 | $1.44M | 0.01% | 00.0% | Unchanged |
| Parametric Portfolio Associates LLC | 32,444 | $1.45M | 0.00% | −554−1.7% | Reduced |
| SG Americas Securities, LLC | 32,802 | $1.46M | 0.01% | +1,907+6.2% | Added |
| Pier 88 Investment Partners LLC | 33,080 | $1.48M | 0.31% | +14,200+75.2% | Added |
| Voya Investment Management LLC | 35,073 | $1.56M | 0.00% | −518−1.5% | Reduced |
| Allianz Asset Management GmbH | 36,145 | $1.61M | 0.00% | +17,410+92.9% | Added |
| Allspring Global Investments Holdings, LLC | 38,612 | $1.72M | 0.00% | +38,612 | New |
| ProShare Advisors LLC | 39,402 | $1.76M | 0.00% | −435−1.1% | Reduced |
| Mark Asset Management LP | 40,370 | $1.80M | 0.26% | +19,841+96.6% | Added |
| Los Angeles Capital Management LLC | 41,092 | $1.83M | 0.01% | −430−1.0% | Reduced |
| Macquarie Group Ltd | 42,161 | $1.88M | 0.00% | +251+0.6% | Added |
| Invesco Ltd. | 44,464 | $1.98M | 0.00% | −3,754−7.8% | Reduced |
| Manufacturers Life Insurance Company, The | 46,496 | $2.09M | 0.00% | −439−0.9% | Reduced |
| Guggenheim Capital LLC | 46,982 | $2.10M | 0.01% | +46,982 | New |
| American International Group, Inc. | 48,350 | $2.16M | 0.01% | −1,447−2.9% | Reduced |
| Jupiter Asset Management Ltd | 50,023 | $2.25M | 0.02% | 00.0% | Unchanged |
| Platinum Investment Management Ltd | 50,971 | $2.27M | 0.06% | +20,180+65.5% | Added |
| AQR Capital Management LLC | 51,667 | $2.30M | 0.00% | −30,382−37.0% | Reduced |
| Woodline Partners LP | 52,454 | $2.34M | 0.03% | +52,454 | New |
| DekaBank Deutsche Girozentrale | 54,400 | $2.37M | 0.01% | +1,500+2.8% | Added |
| Polar Capital Holdings Plc | 53,835 | $2.40M | 0.01% | 00.0% | Unchanged |
| Tygh Capital Management, Inc. | 54,226 | $2.42M | 0.31% | −109−0.2% | Reduced |
| Renaissance Technologies LLC | 54,300 | $2.42M | 0.00% | −41,300−43.2% | Reduced |
| State of New Jersey Common Pension Fund D | 59,618 | $2.66M | 0.01% | +5,310+9.8% | Added |
| ClariVest Asset Management LLC | 65,638 | $2.93M | 0.09% | −5,828−8.2% | Reduced |
| Russell Investments Group, Ltd. | 66,121 | $2.95M | 0.00% | +770+1.2% | Added |
| Putnam Investments LLC | 76,860 | $3.43M | 0.00% | +5,159+7.2% | Added |
| Goldstream Capital Management Ltd | 78,418 | $3.50M | 0.86% | +78,418 | New |
| Legal & General Group Plc | 78,971 | $3.52M | 0.00% | +1,443+1.9% | Added |
| JPMorgan Chase & Co | 83,145 | $3.71M | 0.00% | −15,365−15.6% | Reduced |
| Baker Bros. Advisors LP | 88,738 | $3.96M | 0.02% | 00.0% | Unchanged |
| UBS Group AG | 92,348 | $4.12M | 0.00% | +27,868+43.2% | Added |
| Rhumbline Advisers | 96,649 | $4.31M | 0.01% | −756−0.8% | Reduced |
| Edmond de Rothschild Holding S.A. | 99,880 | $4.46M | 0.10% | −120−0.1% | Reduced |
| Integral Health Asset Management, LLC | 100,000 | $4.46M | 1.24% | +25,000+33.3% | Added |
| Janus Henderson Group PLC | 100,463 | $4.48M | 0.00% | +92,593+1,176.5% | Added |
| Ensign Peak Advisors, Inc | 104,456 | $4.66M | 0.01% | +38,108+57.4% | Added |
| AIA Group Ltd | 107,842 | $4.81M | 0.23% | +9,401+9.5% | Added |
| California State Teachers Retirement System | 116,515 | $5.20M | 0.01% | +2,780+2.4% | Added |
| Deutsche Bank AG | 118,332 | $5.28M | 0.00% | +2,316+2.0% | Added |
| Susquehanna International Group, LLP | 118,895 | $5.30M | 0.01% | +66,798+128.2% | Added |
| Citigroup Inc | 120,381 | $5.37M | 0.00% | +11,356+10.4% | Added |
| Barclays PLC | 120,821 | $5.39M | 0.00% | +49,856+70.3% | Added |
| Rafferty Asset Management, LLC | 121,755 | $5.43M | 0.03% | +61,394+101.7% | Added |
| State of Wisconsin Investment Board | 121,800 | $5.43M | 0.01% | −2,200−1.8% | Reduced |
| TD Asset Management Inc | 122,337 | $5.46M | 0.00% | −4,500−3.5% | Reduced |
| Bank of America Corp | 128,948 | $5.75M | 0.00% | +51,102+65.6% | Added |
| New York State Common Retirement Fund | 134,787 | $6.01M | 0.01% | −22,106−14.1% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 138,563 | $6.24M | 0.03% | +6,509+4.9% | Added |
| Candriam Luxembourg S.C.A. | 141,507 | $6.31M | 0.04% | +77,726+121.9% | Added |
| Wells Fargo & Company | 143,536 | $6.40M | 0.00% | −21,209−12.9% | Reduced |
| Alliancebernstein L.P. | 154,660 | $6.90M | 0.00% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 171,496 | $7.65M | 0.07% | 00.0% | Unchanged |
| Swiss National Bank | 173,700 | $7.75M | 0.00% | −400−0.2% | Reduced |
| Wasatch Advisors Inc | 174,242 | $7.77M | 0.03% | −286−0.2% | Reduced |
| Sectoral Asset Management Inc | 189,600 | $8.46M | 1.27% | +62,100+48.7% | Added |
| Eagle Asset Management Inc | 191,516 | $8.63M | 0.04% | −51,029−21.0% | Reduced |
| California Public Employees Retirement System | 202,177 | $9.02M | 0.01% | +803+0.4% | Added |
| Prudential Financial Inc | 215,801 | $9.71M | 0.01% | +28,339+15.1% | Added |
| AXA S.A. | 220,066 | $9.81M | 0.03% | +18,486+9.2% | Added |
| Tekla Capital Management LLC | 222,420 | $9.92M | 0.32% | 00.0% | Unchanged |
| Jennison Associates LLC | 224,184 | $10.0M | 0.01% | −4,238−1.9% | Reduced |
| Two Sigma Advisers, LP | 269,600 | $12.0M | 0.03% | −151,500−36.0% | Reduced |
| Morgan Stanley | 287,258 | $12.8M | 0.00% | −96,735−25.2% | Reduced |
| Natixis | 293,554 | $13.1M | 0.04% | +14,300+5.1% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 309,040 | $13.8M | 0.03% | −29,690−8.8% | Reduced |
| Principal Financial Group Inc | 330,275 | $14.7M | 0.01% | +26,448+8.7% | Added |
| Yiheng Capital Management, L.P. | 335,184 | $14.9M | 0.76% | +335,184 | New |
| Nuveen Asset Management, LLC | 377,044 | $16.8M | 0.00% | +11,966+3.3% | Added |
| Marshall Wace, LLP | 383,944 | $17.1M | 0.03% | −147,414−27.7% | Reduced |
| Goldman Sachs Group Inc | 410,764 | $18.3M | 0.00% | −645,794−61.1% | Reduced |
| UBS Asset Management Americas Inc | 440,036 | $19.6M | 0.01% | +5,302+1.2% | Added |
| Citadel Advisors LLC | 485,683 | $21.7M | 0.02% | +422,672+670.8% | Added |
| Artisan Partners Limited Partnership | 521,408 | $23.3M | 0.03% | −29,579−5.4% | Reduced |
| American Century Companies Inc | 536,282 | $23.9M | 0.02% | +187,295+53.7% | Added |
| Artal Group S.A. | 600,000 | $26.8M | 0.79% | +100,000+20.0% | Added |
| Charles Schwab Investment Management Inc | 717,190 | $32.0M | 0.01% | +13,438+1.9% | Added |
| Federated Hermes, Inc. | 735,432 | $32.8M | 0.06% | +396,272+116.8% | Added |
| Dimensional Fund Advisors LP | 772,197 | $34.4M | 0.01% | +137,462+21.7% | Added |
| Norges Bank | 846,109 | $37.7M | 0.01% | −7,247−0.8% | Reduced |
| Bank of New York Mellon Corp | 932,592 | $41.6M | 0.01% | +555,873+147.6% | Added |
| Northern Trust Corp | 959,089 | $42.8M | 0.01% | +7,364+0.8% | Added |
| Bamco Inc | 996,304 | $44.4M | 0.09% | −131,615−11.7% | Reduced |
| Pictet Asset Management SA | 998,620 | $44.5M | 0.04% | +130,117+15.0% | Added |