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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
214
+6 vs. Q2 2021
Shares held
84.8M
+4.69M (+5.8%) vs. Q2 2021
Total value
$4.28B
−$2.00B (−31.9%) vs. Q2 2021
New holders
37
81 more added
Sold out
31
65 more reduced

2 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 214 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ3 2021: $4.28B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2021.

Institutions holding DNLI in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Bamco Inc1,127,919$56.9M0.13%−127,305−10.1%Reduced
Geode Capital Management, LLC1,607,394$81.1M0.01%+90,373+6.0%Added
Casdin Capital, LLC1,700,000$85.8M2.14%+90,000+5.6%Added
Credit Suisse AG1,982,473$100.0M0.08%+15,965+0.8%Added
FMR LLC2,675,749$135.0M0.01%+6,666+0.2%Added
Flagship Pioneering Inc.2,730,263$137.7M1.44%00.0%Unchanged
State Street Corp2,798,134$141.2M0.01%+477,674+20.6%Added
Gilder Gagnon Howe & Co LLC2,802,994$141.4M0.73%−32,739−1.2%Reduced
Price T Rowe Associates Inc4,757,965$240.0M0.02%−145,487−3.0%Reduced
Temasek Holdings (Private) Ltd5,369,487$270.9M0.95%+959,030+21.7%Added
BlackRock Inc.7,560,837$381.4M0.01%+524,796+7.5%Added
Crestline Management, LP7,705,039$388.7M36.97%−430,442−5.3%Reduced
Vanguard Group Inc8,168,483$412.1M0.01%+524,353+6.9%Added
Baillie Gifford & Co15,009,816$757.2M0.40%−137,797−0.9%Reduced
Nomura Asset Management Co Ltd0$00.00%−7,210−100.0%Sold out
Euclidean Capital LLC0$00.00%−323,749−100.0%Sold out
Lisanti Capital Growth, LLC0$00.00%−98,130−100.0%Sold out
JGP Global Gestao de Recursos Ltda.0$00.00%−91,760−100.0%Sold out
Avidity Partners Management LP0$00.00%−86,100−100.0%Sold out
Stenahm Asset Managment Ltd0$00.00%−45,000−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−20,959−100.0%Sold out
Public Employees Retirement System of Ohio0$00.00%−20,201−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−19,993−100.0%Sold out
Hillsdale Investment Management Inc.0$00.00%−17,200−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−7,679−100.0%Sold out
Bellecapital International Ltd.0$00.00%−7,644−100.0%Sold out
Engineers Gate Manager LP0$00.00%−6,030−100.0%Sold out
JustInvest LLC0$00.00%−6,012−100.0%Sold out
Man Group plc0$00.00%−5,464−100.0%Sold out
Quantitative Systematic Strategies LLC0$00.00%−4,301−100.0%Sold out
Sargent Investment Group, LLC0$00.00%−3,817−100.0%Sold out
LPL Financial LLC0$00.00%−3,266−100.0%Sold out
Aigen Investment Management, LP0$00.00%−3,243−100.0%Sold out
Grace Capital0$00.00%−3,000−100.0%Sold out
Fernwood Investment Management, LLC0$00.00%−3,000−100.0%Sold out
Plancorp, LLC0$00.00%−2,900−100.0%Sold out
Connable Office Inc0$00.00%−2,699−100.0%Sold out
Toroso Investments, LLC0$00.00%−2,576−100.0%Sold out
Islay Capital Management, LLC0$00.00%−2,013−100.0%Sold out
Advisory Services Network, LLC0$00.00%−1,922−100.0%Sold out
Group One Trading, L.P.0$00.00%−1,193−100.0%Sold out
First Manhattan Co0$00.00%−200−100.0%Sold out
Princeton Global Asset Management LLC0$00.00%−80−100.0%Sold out
Bellwether Advisors, LLC0$00.00%−86−100.0%Sold out
AdvisorNet Financial, Inc0$00.00%−50−100.0%Sold out
Pictet Asset Management Ltd––––Not filed
Hoover Financial Advisors, Inc.––––Not filed