Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 362
- +119 vs. Q1 2026
- Shares held
- 114.8M
- +40.3M (+54.1%) vs. Q1 2026
- Total value
- $5.35B
- +$3.94B (+280.1%) vs. Q1 2026
- New holders
- 148
- 117 more added
- Sold out
- 29
- 64 more reduced
5 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Captrust Financial Advisors | 12,148 | $571.4K | 0.00% | +12,148 | New |
| Heritage Wealth Management, Inc. | 12,000 | $564.5K | 0.28% | −2,375−16.5% | Reduced |
| Advisor Group Holdings, Inc. | 11,952 | $562.2K | 0.00% | +1,393+13.2% | Added |
| Ameritas Investment Partners, Inc. | 11,736 | $552.1K | 0.01% | +4,095+53.6% | Added |
| Glenmede Trust Co NA | 11,548 | $543.2K | 0.00% | +11,548 | New |
| Steward Partners Investment Advisory, LLC | 11,540 | $542.8K | 0.00% | −1,700−12.8% | Reduced |
| Sanctuary Advisors, LLC | 11,502 | $541.1K | 0.00% | +36+0.3% | Added |
| Mount Yale Investment Advisors, LLC | 11,382 | $535.4K | 0.01% | +11,382 | New |
| Teacher Retirement System of Texas | 11,072 | $520.8K | 0.00% | +772+7.5% | Added |
| Entropy Technologies, LP | 10,688 | $502.8K | 0.02% | +10,688 | New |
| Mercer Global Advisors Inc | 10,278 | $483.5K | 0.00% | +10,278 | New |
| Engineers Gate Manager LP | 10,233 | $481.4K | 0.01% | −19,534−65.6% | Reduced |
| Capital Fund Management S.A. | 10,128 | $476.4K | 0.00% | +10,128 | New |
| Bank of Montreal | 10,030 | $471.8K | 0.00% | −2,106−17.4% | Reduced |
| PSP Research LLC | 10,000 | $470.4K | 0.25% | −24,800−71.3% | Reduced |
| Sharpepoint LLC | 10,000 | $470.4K | 0.24% | 00.0% | Unchanged |
| King Wealth | 10,000 | $470.0K | 0.05% | 00.0% | Unchanged |
| Principal Financial Group Inc | 9,952 | $468.1K | 0.00% | +9,952 | New |
| CIBC World Markets Inc. | 9,827 | $462.3K | 0.00% | −222−2.2% | Reduced |
| First Trust Advisors LP | 9,527 | $448.1K | 0.00% | +9,527 | New |
| Commonwealth Equity Services, LLC | 9,450 | $444.5K | 0.00% | −801−7.8% | Reduced |
| Quantbot Technologies LP | 9,230 | $434.2K | 0.02% | +9,230 | New |
| Federation des caisses Desjardins du Quebec | 9,104 | $428.2K | 0.00% | −3,540−28.0% | Reduced |
| Diversify Wealth Management, LLC | 10,025 | $427.6K | 0.01% | −975−8.9% | Reduced |
| Diversify Advisory Services, LLC | 10,025 | $427.6K | 0.01% | +10,025 | New |
| Mangrove Partners | 9,079 | $427.1K | 0.03% | +9,079 | New |
| Gsa Capital Partners LLP | 9,073 | $427.0K | 0.03% | −9,082−50.0% | Reduced |
| Fearless Solutions, LLC dba Best Invest | 8,804 | $414.1K | 0.22% | +8,804 | New |
| North Star Investment Management Corp. | 8,571 | $403.2K | 0.02% | +1,000+13.2% | Added |
| The PNC Financial Services Group, Inc. | 8,569 | $403.1K | 0.00% | +949+12.5% | Added |
| Rafferty Asset Management, LLC | 8,548 | $402.1K | 0.00% | +8,548 | New |
| Fieldview Capital Management, LLC | 8,493 | $399.5K | 0.11% | +8,493 | New |
| Bellevue Group AG | 8,391 | $394.7K | 0.01% | +8,391 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 8,295 | $390.2K | 0.00% | +8,295 | New |
| Flagship Harbor Advisors, LLC | 7,966 | $374.7K | 0.01% | +7,966 | New |
| Wealth Enhancement Advisory Services, LLC | 7,952 | $374.3K | 0.00% | +7,952 | New |
| CIBC Bancorp USA Inc. | 7,711 | $362.7K | 0.00% | +7,711 | New |
| Omers Administration Corp | 7,600 | $357.5K | 0.00% | +7,600 | New |
| Abel Hall, LLC | 7,551 | $355.2K | 0.06% | +7,551 | New |
| Action Point Financial Planning, LLC | 7,483 | $352.0K | 0.04% | +7,483 | New |
| EntryPoint Capital, LLC | 7,331 | $344.9K | 0.08% | +7,331 | New |
| Centiva Capital, LP | 7,242 | $340.7K | 0.01% | +7,242 | New |
| Change Path, LLC | 7,202 | $338.8K | 0.01% | +7,202 | New |
| Jump Financial, LLC | 7,064 | $332.3K | 0.00% | +7,064 | New |
| Chiron Capital Management, LLC | 7,000 | $329.3K | 0.30% | +7,000 | New |
| Creative Planning | 6,906 | $324.9K | 0.00% | +6,906 | New |
| McAdam, LLC | 6,879 | $323.6K | 0.01% | +6,879 | New |
| Marex Group plc | 6,771 | $318.5K | 0.00% | −13,229−66.1% | Reduced |
| Two Sigma Securities, LLC | 6,704 | $315.4K | 0.03% | +6,704 | New |
| Chicago Partners Investment Group LLC | 7,299 | $313.3K | 0.01% | −2,008−21.6% | Reduced |
| Sig Brokerage, LP | 6,563 | $308.7K | 0.05% | +6,563 | New |
| AMG National Trust Bank | 6,369 | $299.6K | 0.01% | +6,369 | New |
| Insigneo Advisory Services, LLC | 6,341 | $298.3K | 0.01% | +6,341 | New |
| Waldron Private Wealth LLC | 6,321 | $297.3K | 0.01% | +6,321 | New |
| Tower Research Capital LLC (TRC) | 6,308 | $296.7K | 0.01% | −997−13.6% | Reduced |
| Bailard, Inc. | 6,277 | $295.3K | 0.01% | +6,277 | New |
| Fiduciary Alliance LLC | 6,000 | $282.2K | 0.02% | +6,000 | New |
| Retirement Financial Solutions, LLC | 6,000 | $282.2K | 0.07% | +6,000 | New |
| Beck Bode, LLC | 5,939 | $279.4K | 0.04% | +5,939 | New |
| CRA Financial Services, LLC | 5,846 | $275.0K | 0.03% | +5,846 | New |
| 49 Wealth Management, LLC | 5,772 | $271.5K | 0.05% | +5,772 | New |
| Alongside, LLC | 5,772 | $271.5K | 0.05% | +5,772 | New |
| Regal Investment Advisors LLC | 5,709 | $268.6K | 0.01% | +5,709 | New |
| MAI Capital Management | 5,686 | $267.5K | 0.00% | +5,583+5,420.4% | Added |
| JustInvest LLC | 5,649 | $265.7K | 0.00% | +5,649 | New |
| Swiss Life Asset Management Ltd | 5,637 | $265.2K | 0.00% | −12,108−68.2% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 5,267 | $248.0K | 0.00% | +5,267 | New |
| Audent Global Asset Management, LLC | 5,200 | $244.6K | 0.27% | +5,200 | New |
| New Republic Capital, LLC | 5,175 | $243.4K | 0.06% | +5,175 | New |
| F/M Investments LLC | 5,139 | $241.7K | 0.01% | +5,139 | New |
| Winton Group Ltd | 5,100 | $239.9K | 0.01% | +5,100 | New |
| State Board of Administration of Florida Retirement System | 5,006 | $235.5K | 0.00% | +5,006 | New |
| Jain Global LLC | 4,983 | $234.4K | 0.00% | +4,983 | New |
| Mirae Asset Global Investments Co., Ltd. | 4,878 | $229.5K | 0.00% | −322−6.2% | Reduced |
| Confluence Wealth Services, Inc. | 4,796 | $225.6K | 0.01% | +4,796 | New |
| Endowment Wealth Management, Inc. | 4,793 | $225.5K | 0.09% | +4,793 | New |
| GWM Advisors LLC | 4,721 | $222.1K | 0.00% | +4,714+67,342.9% | Added |
| Lewis Asset Management, LLC | 4,585 | $215.7K | 0.08% | +4,585 | New |
| Oppenheimer & Co Inc | 4,490 | $211.2K | 0.00% | +4,490 | New |
| DnB Asset Management AS | 4,480 | $210.7K | 0.00% | +4,480 | New |
| Gotham Asset Management, LLC | 4,412 | $207.5K | 0.00% | +4,412 | New |
| KBC Group NV | 3,310 | $156.0K | 0.00% | +1,138+52.4% | Added |
| Fifth Third Bancorp | 3,300 | $155.2K | 0.00% | 00.0% | Unchanged |
| Strategic Investment Advisors | 2,345 | $110.3K | 0.01% | +2,345 | New |
| Allworth Financial LP | 2,336 | $109.9K | 0.00% | +2,209+1,739.4% | Added |
| Caitong International Asset Management Co., Ltd | 2,201 | $103.5K | 0.01% | −1,835−45.5% | Reduced |
| GF Fund Management Co. Ltd. | 2,111 | $99.3K | 0.00% | −102−4.6% | Reduced |
| Crewe Advisors LLC | 1,999 | $94.0K | 0.01% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,711 | $80.5K | 0.00% | −101−5.6% | Reduced |
| High Note Wealth, LLC | 1,600 | $75.3K | 0.01% | +100+6.7% | Added |
| Penserra Capital Management LLC | 1,370 | $64.0K | 0.00% | +1,370 | New |
| US Bancorp | 1,283 | $60.4K | 0.00% | +1,283 | New |
| National Bank of Canada | 1,265 | $59.4K | 0.00% | −443−25.9% | Reduced |
| GAMMA Investing LLC | 1,212 | $57.0K | 0.00% | +101+9.1% | Added |
| Farther Finance Advisors, LLC | 1,162 | $54.7K | 0.00% | +595+104.9% | Added |
| Kemnay Advisory Services Inc. | 1,135 | $53.4K | 0.01% | +329+40.8% | Added |
| Stone House Investment Management, LLC | 1,000 | $47.0K | 0.01% | 00.0% | Unchanged |
| Rothschild Investment LLC | 999 | $47.0K | 0.00% | +707+242.1% | Added |
| First Horizon Corp | 966 | $45.4K | 0.00% | +4+0.4% | Added |
| Nykredit A/S | 947 | $44.5K | 0.00% | +947 | New |