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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
84
−4 vs. Q1 2023
Shares held
3.89M
−51.9K (−1.3%) vs. Q1 2023
Total value
$13.9M
+$1.34M (+10.6%) vs. Q1 2023
New holders
8
13 more added
Sold out
12
12 more reduced

1 institution that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 84 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ2 2023: $13.9M
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2023.

Institutions holding DFTX in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Alyeska Investment Group, L.P.796,962$2.85M0.02%−245,677−23.6%Reduced
Vanguard Group Inc567,885$2.03M0.00%−6,054−1.1%Reduced
BlackRock Inc.553,312$1.98M0.00%+101,320+22.4%Added
Geode Capital Management, LLC371,010$1.32M0.00%+30,955+9.1%Added
Busey Wealth Management244,347$872.3K0.04%00.0%Unchanged
Charles Schwab Investment Management Inc179,809$641.9K0.00%+859+0.5%Added
Cresset Asset Management, LLC159,499$569.4K0.00%+159,499New
Two Sigma Investments, LP157,744$563.1K0.00%−10,441−6.2%Reduced
State Street Corp122,000$435.5K0.00%00.0%Unchanged
Data Collective IV GP, LLC100,350$358.3K0.27%00.0%Unchanged
AdvisorShares Investments LLC91,364$326.2K0.09%−1,946−2.1%Reduced
Bank of New York Mellon Corp64,058$228.7K0.00%+29,782+86.9%Added
Northern Trust Corp62,032$221.5K0.00%+3,641+6.2%Added
Cornercap Investment Counsel Inc56,478$201.6K0.04%+56,478New
Kestra Private Wealth Services, LLC51,339$183.3K0.01%00.0%Unchanged
Group One Trading, L.P.50,153$179.0K0.01%+50,153New
Millennium Management LLC46,553$166.2K0.00%+46,553New
Renaissance Technologies LLC36,519$130.0K0.00%−19,267−34.5%Reduced
Morgan Stanley30,033$107.2K0.00%−7,008−18.9%Reduced
LPL Financial LLC20,835$74.4K0.00%+30.0%Added
Goldman Sachs Group Inc15,816$56.5K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec14,187$50.4K0.00%00.0%Unchanged
FMR LLC12,328$44.0K0.00%+12,180+8,229.7%Added
North Star Investment Management Corp.12,050$43.0K0.00%+2,925+32.1%Added
Freestone Capital Holdings, LLC11,497$41.0K0.00%00.0%Unchanged
Bank of America Corp11,183$39.9K0.00%+2,632+30.8%Added
Wolverine Trading, LLC10,770$37.3K0.00%+10,770New
Barclays PLC9,147$32.7K0.00%00.0%Unchanged
Royal Bank of Canada7,474$27.0K0.00%+2,824+60.7%Added
Deutsche Bank AG5,613$20.0K0.00%−2,408−30.0%Reduced
Advisor Group Holdings, Inc.3,763$13.5K0.00%−311−7.6%Reduced
TD Waterhouse Canada Inc.1,797$7.92K0.00%+1,062+144.5%Added
Moisand Fitzgerald Tamayo, LLC2,000$7.14K0.00%+2,000New
Crewe Advisors LLC1,999$7.14K0.00%00.0%Unchanged
CWM, LLC1,863$7.00K0.00%00.0%Unchanged
National Bank of Canada1,521$5.36K0.00%−46−2.9%Reduced
UBS Group AG752$2.68K0.00%−9,050−92.3%Reduced
Edmond de Rothschild Holding S.A.666$2.38K0.00%00.0%Unchanged
Column Capital Advisors, LLC610$2.18K0.00%00.0%Unchanged
Parallel Advisors, LLC543$1.94K0.00%00.0%Unchanged
Tortoise Investment Management, LLC400$1.43K0.00%00.0%Unchanged
Albion Financial Group323$1.15K0.00%00.0%Unchanged
Emfo, LLC300$1.07K0.00%00.0%Unchanged
Wells Fargo & Company245$8750.00%+17+7.5%Added
Kistler-Tiffany Companies, LLC218$7790.00%00.0%Unchanged
GWM Advisors LLC148$5280.00%+133+886.7%Added
Princeton Global Asset Management LLC100$3570.00%00.0%Unchanged
Farther Finance Advisors, LLC100$3570.00%00.0%Unchanged
Allworth Financial LP66$2360.00%00.0%Unchanged
US Bancorp66$2360.00%00.0%Unchanged
Arrow Financial Corp66$2360.00%00.0%Unchanged
Hollencrest Capital Management66$2360.00%00.0%Unchanged
Westside Investment Management, Inc.66$2360.00%00.0%Unchanged
Clearview Wealth Advisors LLC66$2360.00%00.0%Unchanged
Tradewinds Capital Management, LLC53$1900.00%00.0%Unchanged
Impact Partnership Wealth, LLC48$1710.00%+48New
Plante Moran Financial Advisors, LLC36$1290.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co33$1180.00%−33−50.0%Reduced
Chesapeake Asset Management LLC33$1170.00%00.0%Unchanged
Glen Eagle Advisors, LLC30$1080.00%00.0%Unchanged
HighMark Wealth Management LLC29$1040.00%00.0%Unchanged
SRS Capital Advisors, Inc.28$1000.00%00.0%Unchanged
Nelson, Van Denburg & Campbell Wealth Management Group, LLC24$850.00%00.0%Unchanged
Pacifica Partners Inc.20$750.00%00.0%Unchanged
JPMorgan Chase & Co16$750.00%00.0%Unchanged
FinTrust Capital Advisors, LLC33$730.00%00.0%Unchanged
Gradient Investments LLC18$640.00%−20−52.6%Reduced
NewSquare Capital LLC17$610.00%00.0%Unchanged
SJS Investment Consulting Inc.14$500.00%00.0%Unchanged
Harbour Investments, Inc.10$360.00%00.0%Unchanged
Focused Wealth Management, Inc10$360.00%00.0%Unchanged
JJJ Advisors Inc.10$360.00%00.0%Unchanged
CNB Bank10$360.00%00.0%Unchanged
Assetmark, Inc8$290.00%+8New
Belmont Capital, LLC6$210.00%00.0%Unchanged
Strategic Investment Solutions, Inc.6$210.00%00.0%Unchanged
AdvisorNet Financial, Inc3$110.00%00.0%Unchanged
Signaturefd, LLC2$70.00%00.0%Unchanged
Horan Securities, Inc.2$70.00%00.0%Unchanged
Huntington National Bank1$10.00%00.0%Unchanged
Cutler Group LP86$00.00%00.0%Unchanged
PrairieView Partners, LLC4$00.00%00.0%Unchanged
TSFG, LLC24$00.00%00.0%Unchanged
IFP Advisors, Inc30––00.0%Unchanged
Susquehanna International Group, LLP0$00.00%−232,027−100.0%Sold out
Man Group plc0$00.00%–Sold out
Citadel Advisors LLC0$00.00%−14,790−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−12,400−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−3,103−100.0%Sold out
Belpointe Asset Management LLC0$00.00%−604−100.0%Sold out
Robbins Farley LLC0$00.00%−28−100.0%Sold out
Advisory Services Network, LLC0$00.00%−9−100.0%Sold out
Grey Fox Wealth Advisors, LLC0$00.00%−6−100.0%Sold out
Ogorek Anthony Joseph0$00.00%−16−100.0%Sold out
Front Row Advisors LLC0$00.00%−133−100.0%Sold out
VitalStone Financial, LLC0$00.00%−350−100.0%Sold out
Baldrige Asset Management LLC––––Not filed