Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Definium Therapeutics, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 158
- +9 vs. Q2 2024
- Shares held
- 49.5M
- +13.3M (+36.9%) vs. Q2 2024
- Total value
- $281.6M
- +$21.1M (+8.1%) vs. Q2 2024
- New holders
- 30
- 50 more added
- Sold out
- 21
- 29 more reduced
3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Commodore Capital LP | 8,000,000 | $45.5M | 2.84% | +854,112+12.0% | Added |
| Deep Track Capital, LP | 7,065,099 | $40.2M | 1.28% | +961,282+15.7% | Added |
| BlackRock, Inc. | 5,664,033 | $32.2M | 0.00% | +5,664,033 | New |
| Blackstone Group Inc. | 3,912,479 | $22.3M | 0.10% | +2,014,154+106.1% | Added |
| Driehaus Capital Management LLC | 3,894,127 | $22.2M | 0.19% | +1,355,717+53.4% | Added |
| Octagon Capital Advisors LP | 3,018,000 | $17.2M | 2.75% | +865,000+40.2% | Added |
| Marshall Wace, LLP | 2,287,865 | $13.0M | 0.02% | +127,662+5.9% | Added |
| Vanguard Group Inc | 1,948,307 | $11.1M | 0.00% | +206,904+11.9% | Added |
| State Street Corp | 1,814,829 | $10.3M | 0.00% | +9,782+0.5% | Added |
| Geode Capital Management, LLC | 1,677,702 | $9.55M | 0.00% | +162,933+10.8% | Added |
| Tri Locum Partners LP | 1,662,953 | $9.46M | 2.27% | +1,280,898+335.3% | Added |
| Woodline Partners LP | 1,002,544 | $5.70M | 0.05% | +1,294+0.1% | Added |
| AWM Investment Company, Inc. | 853,000 | $4.85M | 0.59% | +20,000+2.4% | Added |
| Ally Bridge Group (NY) LLC | 788,508 | $4.49M | 2.40% | −176,918−18.3% | Reduced |
| Northern Trust Corp | 608,277 | $3.46M | 0.00% | +424,363+230.7% | Added |
| Charles Schwab Investment Management Inc | 602,544 | $3.43M | 0.00% | +46,187+8.3% | Added |
| Morgan Stanley | 355,619 | $2.02M | 0.00% | +197,638+125.1% | Added |
| Bank of America Corp | 312,591 | $1.78M | 0.00% | +236,833+312.6% | Added |
| Two Sigma Investments, LP | 279,039 | $1.59M | 0.00% | −404,648−59.2% | Reduced |
| Nuveen Asset Management, LLC | 277,478 | $1.58M | 0.00% | +73,338+35.9% | Added |
| Bank of New York Mellon Corp | 189,783 | $1.08M | 0.00% | −56,425−22.9% | Reduced |
| Wellington Management Group LLP | 185,722 | $1.06M | 0.00% | +109,152+142.6% | Added |
| Goldman Sachs Group Inc | 169,949 | $967.0K | 0.00% | +100,435+144.5% | Added |
| Barclays PLC | 136,098 | $774.4K | 0.00% | +91,271+203.6% | Added |
| UBS Group AG | 128,298 | $730.0K | 0.00% | +71,810+127.1% | Added |
| Swiss National Bank | 119,900 | $682.2K | 0.00% | +9,000+8.1% | Added |
| Moloney Securities Asset Management, LLC | 115,511 | $657.3K | 0.09% | −19,800−14.6% | Reduced |
| AdvisorShares Investments LLC | 109,166 | $621.2K | 0.12% | −15,000−12.1% | Reduced |
| Data Collective IV GP, LLC | 100,350 | $571.0K | 0.35% | 00.0% | Unchanged |
| Rhumbline Advisers | 95,827 | $545.2K | 0.00% | +1,711+1.8% | Added |
| Citigroup Inc | 84,496 | $480.8K | 0.00% | +58,591+226.2% | Added |
| Squarepoint Ops LLC | 80,121 | $455.9K | 0.00% | +80,121 | New |
| Millennium Management LLC | 79,210 | $450.7K | 0.00% | +79,210 | New |
| Alliancebernstein L.P. | 75,330 | $428.6K | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 70,353 | $400.3K | 0.00% | −7,726−9.9% | Reduced |
| Alyeska Investment Group, L.P. | 66,694 | $379.5K | 0.00% | +66,694 | New |
| Ikarian Capital, LLC | 62,481 | $355.5K | 0.11% | −100,000−61.5% | Reduced |
| XTX Topco Ltd | 59,222 | $337.0K | 0.02% | +59,222 | New |
| California State Teachers Retirement System | 58,484 | $332.8K | 0.00% | +2,184+3.9% | Added |
| Legal & General Group Plc | 57,675 | $328.2K | 0.00% | +4,442+8.3% | Added |
| Royal Bank of Canada | 56,688 | $323.0K | 0.00% | −10,210−15.3% | Reduced |
| Scotia Capital Inc. | 53,951 | $306.8K | 0.00% | 00.0% | Unchanged |
| Oppenheimer & Co Inc | 52,381 | $298.0K | 0.00% | +52,381 | New |
| Kestra Private Wealth Services, LLC | 51,339 | $292.1K | 0.01% | 00.0% | Unchanged |
| LPL Financial LLC | 47,895 | $272.5K | 0.00% | +1,630+3.5% | Added |
| Deutsche Bank AG | 46,879 | $266.7K | 0.00% | +10,189+27.8% | Added |
| Citadel Advisors LLC | 42,843 | $243.8K | 0.00% | +25,263+143.7% | Added |
| MetLife Investment Management | 42,549 | $242.1K | 0.00% | +42,549 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 39,508 | $224.8K | 0.00% | +39,508 | New |
| Corebridge Financial, Inc. | 38,495 | $219.0K | 0.00% | −238−0.6% | Reduced |
| JPMorgan Chase & Co | 36,995 | $210.5K | 0.00% | +2,797+8.2% | Added |
| Invesco Ltd. | 36,836 | $209.6K | 0.00% | +395+1.1% | Added |
| Caxton Corp | 34,073 | $193.9K | 0.80% | +3,690+12.1% | Added |
| Jane Street Group, LLC | 30,721 | $174.8K | 0.00% | −47,552−60.8% | Reduced |
| Fore Capital, LLC | 30,000 | $170.7K | 0.33% | +15,000+100.0% | Added |
| Janus Henderson Group PLC | 28,000 | $159.2K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 26,605 | $151.4K | 0.00% | −739−2.7% | Reduced |
| Balyasny Asset Management LLC | 26,386 | $150.1K | 0.00% | +8,723+49.4% | Added |
| Wells Fargo & Company | 24,705 | $140.6K | 0.00% | −665−2.6% | Reduced |
| Voya Investment Management LLC | 24,303 | $138.3K | 0.00% | +95+0.4% | Added |
| Bailard, Inc. | 24,100 | $137.1K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 23,473 | $133.6K | 0.00% | +23,473 | New |
| Price T Rowe Associates Inc | 22,952 | $131.0K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 22,773 | $129.6K | 0.00% | +22,773 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 22,226 | $126.5K | 0.00% | +4,079+22.5% | Added |
| GTS Securities LLC | 21,567 | $122.7K | 0.00% | −6,218−22.4% | Reduced |
| Sanctuary Advisors, LLC | 16,002 | $121.0K | 0.00% | +16,002 | New |
| Profund Advisors LLC | 20,843 | $118.6K | 0.00% | −30.0% | Reduced |
| Rathbone Brothers plc | 20,200 | $114.9K | 0.00% | −4,000−16.5% | Reduced |
| Mitchell McLeod Pugh & Williams Inc | 20,000 | $113.8K | 0.02% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 19,922 | $113.4K | 0.00% | +2,706+15.7% | Added |
| Commonwealth Equity Services, LLC | 19,564 | $111.0K | 0.00% | −5,402−21.6% | Reduced |
| Two Sigma Advisers, LP | 19,250 | $109.5K | 0.00% | −65,767−77.4% | Reduced |
| Rafferty Asset Management, LLC | 18,658 | $106.2K | 0.00% | +1,359+7.9% | Added |
| Wolverine Trading, LLC | 17,351 | $101.5K | 0.00% | +77+0.4% | Added |
| Boothbay Fund Management, LLC | 17,774 | $101.1K | 0.00% | −28,447−61.5% | Reduced |
| Arizona State Retirement System | 17,570 | $100.0K | 0.00% | +1,781+11.3% | Added |
| New York State Common Retirement Fund | 17,100 | $97.3K | 0.00% | −12,000−41.2% | Reduced |
| Sequoia Financial Advisors, LLC | 16,578 | $94.3K | 0.00% | −110−0.7% | Reduced |
| Mercer Global Advisors Inc | 16,520 | $93.0K | 0.00% | +2,000+13.8% | Added |
| Stoneridge Investment Partners LLC | 16,362 | $93.0K | 0.03% | +16,362 | New |
| SG Americas Securities, LLC | 16,402 | $93.0K | 0.00% | +16,402 | New |
| Teacher Retirement System of Texas | 15,290 | $87.0K | 0.00% | +2,901+23.4% | Added |
| Sherbrooke Park Advisers LLC | 13,827 | $78.7K | 0.02% | +13,827 | New |
| ProShare Advisors LLC | 13,605 | $77.4K | 0.00% | +13,605 | New |
| HighTower Advisors, LLC | 12,979 | $73.0K | 0.00% | −1,551−10.7% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 12,789 | $72.8K | 0.00% | 00.0% | Unchanged |
| Change Path, LLC | 12,462 | $70.9K | 0.00% | −4,382−26.0% | Reduced |
| FMR LLC | 12,142 | $69.1K | 0.00% | +414+3.5% | Added |
| Voloridge Investment Management, LLC | 11,198 | $63.7K | 0.00% | −15,649−58.3% | Reduced |
| Blair William & Co | 11,000 | $62.6K | 0.00% | −268−2.4% | Reduced |
| Wealth Alliance | 11,000 | $62.6K | 0.01% | 00.0% | Unchanged |
| Diversify Wealth Management, LLC | 10,000 | $62.2K | 0.01% | 00.0% | Unchanged |
| SEI Investments Co | 10,415 | $59.3K | 0.00% | +10,415 | New |
| Wealth Enhancement Advisory Services, LLC | 10,200 | $58.0K | 0.00% | +10,200 | New |
| North Star Investment Management Corp. | 9,401 | $53.5K | 0.00% | +6,901+276.0% | Added |
| Advisor Group Holdings, Inc. | 7,976 | $45.4K | 0.00% | +3,742+88.4% | Added |
| Ameritas Investment Partners, Inc. | 7,053 | $40.1K | 0.00% | 00.0% | Unchanged |
| PEAK6 Investments LLC | 6,223 | $35.4K | 0.00% | −19,477−75.8% | Reduced |
| TD Waterhouse Canada Inc. | 4,335 | $24.3K | 0.00% | −163−3.6% | Reduced |