Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2021
Institutional positions in Definium Therapeutics, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 175
- +22 vs. Q2 2021
- Shares held
- 44.7M
- +6.88M (+18.2%) vs. Q2 2021
- Total value
- $104.8M
- −$26.1M (−19.9%) vs. Q2 2021
- New holders
- 40
- 56 more added
- Sold out
- 18
- 34 more reduced
3 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock Inc. | 16,681,997 | $38.9M | 0.00% | +997,490+6.4% | Added |
| State Street Corp | 5,634,088 | $13.1M | 0.00% | +1,159,118+25.9% | Added |
| Geode Capital Management, LLC | 2,913,033 | $6.79M | 0.00% | +200,941+7.4% | Added |
| Northern Trust Corp | 2,589,317 | $6.03M | 0.00% | +2,370,459+1,083.1% | Added |
| Vanguard Group Inc | 1,875,408 | $4.37M | 0.00% | +207,346+12.4% | Added |
| Millennium Management LLC | 1,392,359 | $3.24M | 0.00% | +350,178+33.6% | Added |
| Susquehanna International Group, LLP | 1,061,186 | $2.47M | 0.00% | −177,056−14.3% | Reduced |
| Goldman Sachs Group Inc | 1,016,014 | $2.37M | 0.00% | +742,184+271.0% | Added |
| Bank of New York Mellon Corp | 885,835 | $2.06M | 0.00% | +134,482+17.9% | Added |
| Busey Wealth Management | 816,934 | $1.90M | 0.08% | +816,934 | New |
| Charles Schwab Investment Management Inc | 737,060 | $1.72M | 0.00% | +54,260+7.9% | Added |
| Swiss National Bank | 716,500 | $1.72M | 0.00% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 335,900 | $783.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 332,906 | $776.0K | 0.00% | +332,906 | New |
| MMCAP International Inc. SPC | 325,804 | $759.0K | 0.05% | +325,804 | New |
| Deutsche Bank AG | 314,629 | $732.0K | 0.00% | +25,705+8.9% | Added |
| Rhumbline Advisers | 307,204 | $716.0K | 0.00% | +14,880+5.1% | Added |
| Simplex Trading, LLC | 198,466 | $680.0K | 0.02% | −5,805−2.8% | Reduced |
| Citadel Advisors LLC | 270,095 | $629.0K | 0.00% | −50,168−15.7% | Reduced |
| JPMorgan Chase & Co | 128,678 | $603.0K | 0.00% | −184,601−58.9% | Reduced |
| Credit Suisse AG | 237,331 | $553.0K | 0.00% | −703−0.3% | Reduced |
| Manufacturers Life Insurance Company, The | 176,046 | $537.0K | 0.00% | +248+0.1% | Added |
| New York State Common Retirement Fund | 206,923 | $482.0K | 0.00% | −68,977−25.0% | Reduced |
| Invesco Ltd. | 199,632 | $465.0K | 0.00% | +46,695+30.5% | Added |
| Penserra Capital Management LLC | 196,020 | $456.0K | 0.01% | +72,611+58.8% | Added |
| Morgan Stanley | 194,828 | $453.0K | 0.00% | +22,894+13.3% | Added |
| American International Group, Inc. | 190,445 | $444.0K | 0.00% | +9,975+5.5% | Added |
| California State Teachers Retirement System | 188,695 | $440.0K | 0.00% | −255,577−57.5% | Reduced |
| Bank of Montreal | 169,612 | $400.0K | 0.00% | +21,119+14.2% | Added |
| D. E. Shaw & Co., Inc. | 170,522 | $397.0K | 0.00% | +37,719+28.4% | Added |
| Belvedere Trading LLC | 171,274 | $392.0K | 0.11% | −11,870−6.5% | Reduced |
| tru Independence LLC | 167,293 | $385.0K | 0.11% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 149,962 | $361.0K | 0.00% | +29,770+24.8% | Added |
| AdvisorShares Investments LLC | 152,518 | $355.0K | 0.06% | +72,518+90.6% | Added |
| Group One Trading, L.P. | 147,657 | $344.0K | 0.01% | +35,568+31.7% | Added |
| Shay Capital LLC | 141,250 | $329.0K | 0.10% | −29,200−17.1% | Reduced |
| SG Americas Securities, LLC | 141,023 | $329.0K | 0.00% | +123,477+703.7% | Added |
| BIT Capital GmbH | 140,000 | $326.2K | 0.02% | 00.0% | Unchanged |
| Voya Investment Management LLC | 134,392 | $313.0K | 0.00% | +7,913+6.3% | Added |
| Parametric Portfolio Associates LLC | 125,880 | $293.0K | 0.00% | +77,430+159.8% | Added |
| HighTower Advisors, LLC | 112,203 | $264.0K | 0.00% | +54,721+95.2% | Added |
| Royal Bank of Canada | 96,013 | $223.0K | 0.00% | −13,256−12.1% | Reduced |
| MetLife Investment Management | 92,265 | $215.0K | 0.00% | −33,654−26.7% | Reduced |
| Scotia Capital Inc. | 83,147 | $194.0K | 0.00% | +90.0% | Added |
| STRS Ohio | 79,800 | $185.0K | 0.00% | +5,100+6.8% | Added |
| Creative Planning | 76,232 | $178.0K | 0.00% | +54,096+244.4% | Added |
| Advisor Group Holdings, Inc. | 73,292 | $172.0K | 0.00% | +37,000+102.0% | Added |
| Principal Financial Group Inc | 73,001 | $170.0K | 0.00% | +21,507+41.8% | Added |
| Gofen & Glossberg LLC | 72,500 | $169.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 70,945 | $165.3K | 0.00% | −25,461−26.4% | Reduced |
| Huntington National Bank | 60,000 | $140.0K | 0.00% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 60,504 | $140.0K | 0.00% | +19,321+46.9% | Added |
| Legal & General Group Plc | 53,688 | $129.0K | 0.00% | +2,065+4.0% | Added |
| Jane Street Group, LLC | 51,035 | $123.0K | 0.00% | −571,329−91.8% | Reduced |
| State Board of Administration of Florida Retirement System | 48,130 | $112.0K | 0.00% | +48,130 | New |
| Ergoteles LLC | 48,108 | $112.0K | 0.00% | +48,108 | New |
| Stokes Family Office, LLC | 46,095 | $111.0K | 0.02% | 00.0% | Unchanged |
| Stifel Financial Corp | 44,980 | $105.0K | 0.00% | +240+0.5% | Added |
| ProShare Advisors LLC | 44,591 | $104.0K | 0.00% | −38,965−46.6% | Reduced |
| Envestnet Asset Management Inc | 44,030 | $103.0K | 0.00% | +44,030 | New |
| LPL Financial LLC | 43,885 | $102.0K | 0.00% | −285−0.6% | Reduced |
| First Republic Investment Management, Inc. | 42,337 | $99.0K | 0.00% | +42,337 | New |
| Citigroup Inc | 40,527 | $98.0K | 0.00% | +25,197+164.4% | Added |
| Toronto Dominion Bank | 39,823 | $96.0K | 0.00% | −6,400−13.8% | Reduced |
| HSBC Holdings PLC | 28,115 | $93.0K | 0.00% | +28,115 | New |
| Jaffetilchin Investment Partners, LLC | 36,855 | $89.0K | 0.01% | −725−1.9% | Reduced |
| Virtu Financial LLC | 37,355 | $87.0K | 0.01% | −195,551−84.0% | Reduced |
| Bank of America Corp | 37,194 | $87.0K | 0.00% | −12,615−25.3% | Reduced |
| Stratos Wealth Partners, LTD. | 33,604 | $78.0K | 0.00% | +1,128+3.5% | Added |
| Intersect Capital LLC | 32,500 | $76.0K | 0.01% | 00.0% | Unchanged |
| Koshinski Asset Management, Inc. | 32,272 | $75.2K | 0.01% | +17,112+112.9% | Added |
| Arete Wealth Advisors, LLC | 32,052 | $75.0K | 0.01% | −446−1.4% | Reduced |
| Hochman Cole Investment Advisors, Inc. | 31,760 | $74.0K | 0.03% | +31,760 | New |
| Cutler Group LP | 31,021 | $72.0K | 0.01% | +23,403+307.2% | Added |
| Cubist Systematic Strategies, LLC | 30,600 | $71.0K | 0.00% | +26,800+705.3% | Added |
| IHT Wealth Management, LLC | 30,000 | $70.0K | 0.01% | 00.0% | Unchanged |
| American Portfolios Advisors | 30,000 | $69.9K | 0.00% | 00.0% | Unchanged |
| Shell Asset Management Co | 28,813 | $69.0K | 0.00% | −1,209−4.0% | Reduced |
| Price T Rowe Associates Inc | 28,786 | $67.0K | 0.00% | +985+3.5% | Added |
| Wolverine Trading, LLC | 27,394 | $64.0K | 0.00% | −51,970−65.5% | Reduced |
| Pictet Asset Management SA | 27,463 | $64.0K | 0.00% | +27,463 | New |
| Accurate Wealth Management, LLC | 26,440 | $63.0K | 0.06% | +3,890+17.3% | Added |
| Wells Fargo & Company | 26,193 | $61.0K | 0.00% | +25,683+5,035.9% | Added |
| Ameritas Investment Partners, Inc. | 25,253 | $59.0K | 0.00% | 00.0% | Unchanged |
| Conservest Capital Advisors, Inc. | 23,444 | $55.0K | 0.01% | 00.0% | Unchanged |
| Prudential Financial Inc | 22,750 | $53.0K | 0.00% | +1,110+5.1% | Added |
| K.J. Harrison & Partners Inc | 21,500 | $52.0K | 0.01% | 00.0% | Unchanged |
| Wedbush Securities Inc | 22,500 | $52.0K | 0.00% | +22,500 | New |
| Eudaimonia Partners, LLC | 20,000 | $47.0K | 0.01% | +5,000+33.3% | Added |
| Mackenzie Financial Corp | 18,914 | $45.0K | 0.00% | +18,914 | New |
| Texas Yale Capital Corp. | 17,300 | $40.0K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 16,659 | $38.7K | 0.00% | −600−3.5% | Reduced |
| Sara-Bay Financial | 16,204 | $38.0K | 0.01% | −3,000−15.6% | Reduced |
| Xponance, Inc. | 16,369 | $38.0K | 0.00% | −1,261−7.2% | Reduced |
| Invst, LLC | 16,058 | $37.0K | 0.01% | 00.0% | Unchanged |
| Close Asset Management Ltd | 16,000 | $37.0K | 0.00% | +16,000 | New |
| CIBC World Markets Inc. | 15,371 | $36.0K | 0.00% | +15,371 | New |
| Veritable, L.P. | 15,100 | $35.0K | 0.00% | 00.0% | Unchanged |
| Platform Technology Partners | 15,000 | $35.0K | 0.02% | 00.0% | Unchanged |
| United Capital Financial Advisers, LLC | 15,079 | $35.0K | 0.00% | +15,079 | New |