Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 159
- −16 vs. Q4 2021
- Shares held
- 48.4M
- −3.55M (−6.8%) vs. Q4 2021
- Total value
- $53.6M
- −$18.4M (−25.6%) vs. Q4 2021
- New holders
- 32
- 34 more added
- Sold out
- 48
- 41 more reduced
1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock Inc. | 16,434,210 | $18.2M | 0.00% | −631,364−3.7% | Reduced |
| State Street Corp | 6,145,503 | $6.82M | 0.00% | +416,765+7.3% | Added |
| Geode Capital Management, LLC | 2,822,682 | $3.13M | 0.00% | −86,053−3.0% | Reduced |
| Northern Trust Corp | 2,272,017 | $2.52M | 0.00% | −267,190−10.5% | Reduced |
| Morgan Stanley | 1,974,299 | $2.19M | 0.00% | −425,584−17.7% | Reduced |
| Vanguard Group Inc | 1,903,150 | $2.11M | 0.00% | −71,849−3.6% | Reduced |
| Data Collective IV GP, LLC | 1,505,248 | $1.67M | 0.35% | 00.0% | Unchanged |
| Busey Wealth Management | 1,248,201 | $1.39M | 0.06% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,200,074 | $1.33M | 0.00% | −460,676−27.7% | Reduced |
| Swiss National Bank | 951,100 | $1.08M | 0.00% | +178,300+23.1% | Added |
| Bank of New York Mellon Corp | 936,388 | $1.04M | 0.00% | +16,746+1.8% | Added |
| Charles Schwab Investment Management Inc | 718,559 | $798.0K | 0.00% | −30,829−4.1% | Reduced |
| Susquehanna International Group, LLP | 683,954 | $759.0K | 0.00% | −369,884−35.1% | Reduced |
| Two Sigma Investments, LP | 677,780 | $752.0K | 0.00% | −445,986−39.7% | Reduced |
| AdvisorShares Investments LLC | 649,168 | $721.0K | 0.12% | +231,646+55.5% | Added |
| Group One Trading, L.P. | 535,205 | $594.0K | 0.01% | +59,346+12.5% | Added |
| Millennium Management LLC | 436,336 | $484.0K | 0.00% | −639,817−59.5% | Reduced |
| Penserra Capital Management LLC | 480,853 | $442.0K | 0.01% | +238,737+98.6% | Added |
| Deutsche Bank AG | 366,292 | $406.0K | 0.00% | +34,574+10.4% | Added |
| Goldman Sachs Group Inc | 347,777 | $386.0K | 0.00% | +119,075+52.1% | Added |
| Jane Street Group, LLC | 297,788 | $338.0K | 0.00% | +122,583+70.0% | Added |
| Rhumbline Advisers | 301,676 | $335.0K | 0.00% | −8,267−2.7% | Reduced |
| Alliancebernstein L.P. | 291,800 | $324.0K | 0.00% | +1,100+0.4% | Added |
| Credit Suisse AG | 279,053 | $309.0K | 0.00% | +63,963+29.7% | Added |
| MMCAP International Inc. SPC | 240,300 | $267.0K | 0.02% | +240,300 | New |
| Man Group plc | 219,780 | $244.0K | 0.00% | +110,380+100.9% | Added |
| New York State Common Retirement Fund | 206,560 | $229.0K | 0.00% | +302+0.1% | Added |
| Commonwealth Equity Services, LLC | 185,625 | $206.0K | 0.00% | +19,423+11.7% | Added |
| tru Independence LLC | 167,293 | $183.0K | 0.05% | 00.0% | Unchanged |
| American International Group, Inc. | 159,905 | $177.0K | 0.00% | −25,009−13.5% | Reduced |
| Bank of Montreal | 146,833 | $175.0K | 0.00% | +103+0.1% | Added |
| JPMorgan Chase & Co | 151,310 | $168.0K | 0.00% | +16,666+12.4% | Added |
| MetLife Investment Management | 146,176 | $162.3K | 0.00% | +7,857+5.7% | Added |
| California State Teachers Retirement System | 137,970 | $153.0K | 0.00% | −50,099−26.6% | Reduced |
| Manufacturers Life Insurance Company, The | 135,904 | $150.9K | 0.00% | −41,852−23.5% | Reduced |
| Invesco Ltd. | 133,867 | $149.0K | 0.00% | −13,127−8.9% | Reduced |
| HighTower Advisors, LLC | 104,975 | $119.0K | 0.00% | +45,747+77.2% | Added |
| Ikarian Capital, LLC | 105,958 | $118.0K | 0.04% | +5,958+6.0% | Added |
| Cresset Asset Management, LLC | 101,100 | $112.0K | 0.00% | −100,000−49.7% | Reduced |
| Parallax Volatility Advisers, L.P. | 99,901 | $111.0K | 0.00% | +46,338+86.5% | Added |
| Fore Capital, LLC | 100,000 | $111.0K | 0.13% | +100,000 | New |
| Royal Bank of Canada | 92,643 | $103.0K | 0.00% | −51,034−35.5% | Reduced |
| Legal & General Group Plc | 84,554 | $96.0K | 0.00% | +30,064+55.2% | Added |
| Scotia Capital Inc. | 83,783 | $93.0K | 0.00% | −3,825−4.4% | Reduced |
| STRS Ohio | 79,800 | $88.0K | 0.00% | 00.0% | Unchanged |
| Audent Global Asset Management, LLC | 78,000 | $87.0K | 0.05% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 78,132 | $87.0K | 0.00% | +43,337+124.5% | Added |
| Gofen & Glossberg LLC | 72,500 | $80.0K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 71,163 | $79.0K | 0.00% | −130,566−64.7% | Reduced |
| ProShare Advisors LLC | 60,391 | $67.0K | 0.00% | −15,621−20.6% | Reduced |
| Principal Financial Group Inc | 58,480 | $65.0K | 0.00% | −709−1.2% | Reduced |
| Creative Planning | 55,495 | $62.0K | 0.00% | −2,585−4.5% | Reduced |
| Two Sigma Advisers, LP | 52,000 | $58.0K | 0.00% | −4,400−7.8% | Reduced |
| Barclays PLC | 52,281 | $58.0K | 0.00% | +52,281 | New |
| Stifel Financial Corp | 49,740 | $56.0K | 0.00% | +3,500+7.6% | Added |
| State Board of Administration of Florida Retirement System | 48,230 | $53.0K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 47,944 | $53.0K | 0.00% | +47,944 | New |
| Bank of America Corp | 47,463 | $52.0K | 0.00% | −107,995−69.5% | Reduced |
| Toronto Dominion Bank | 45,523 | $52.0K | 0.00% | +4,600+11.2% | Added |
| HSBC Holdings PLC | 43,081 | $48.0K | 0.00% | +4,852+12.7% | Added |
| Shell Asset Management Co | 37,982 | $43.0K | 0.00% | 00.0% | Unchanged |
| Accurate Wealth Management, LLC | 34,340 | $38.0K | 0.02% | +34,340 | New |
| National Bank of Canada | 33,510 | $37.0K | 0.00% | −143,543−81.1% | Reduced |
| Stratos Wealth Partners, LTD. | 33,604 | $37.0K | 0.00% | 00.0% | Unchanged |
| Cutler Group LP | 33,389 | $37.0K | 0.00% | +3,500+11.7% | Added |
| Alpine Global Management, LLC | 31,750 | $35.0K | 0.01% | −27,940−46.8% | Reduced |
| American Portfolios Advisors | 30,000 | $33.3K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 30,001 | $33.0K | 0.00% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 29,492 | $33.0K | 0.00% | +6,506+28.3% | Added |
| Pictet Asset Management SA | 27,463 | $30.0K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 26,036 | $29.0K | 0.00% | +26,036 | New |
| Parametric Portfolio Associates LLC | 25,362 | $28.0K | 0.00% | −188,790−88.2% | Reduced |
| Ameritas Investment Partners, Inc. | 25,253 | $28.0K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 21,331 | $24.0K | 0.00% | −85,500−80.0% | Reduced |
| K.J. Harrison & Partners Inc | 21,500 | $24.0K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 21,940 | $24.0K | 0.00% | +21,940 | New |
| Fisher Asset Management, LLC | 20,500 | $23.0K | 0.00% | +375+1.9% | Added |
| IFP Advisors, Inc | 29,709 | $23.0K | 0.00% | +18,652+168.7% | Added |
| Glenmede Trust Co NA | 21,585 | $23.0K | 0.00% | +21,585 | New |
| Freestone Capital Holdings, LLC | 20,685 | $23.0K | 0.00% | +20,685 | New |
| Prudential Financial Inc | 20,240 | $22.0K | 0.00% | 00.0% | Unchanged |
| Regions Financial Corp | 20,000 | $22.0K | 0.00% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 19,191 | $22.0K | 0.00% | 00.0% | Unchanged |
| Close Asset Management Ltd | 16,000 | $22.0K | 0.00% | 00.0% | Unchanged |
| Eudaimonia Partners, LLC | 20,000 | $22.0K | 0.00% | +20,000 | New |
| Two Sigma Securities, LLC | 18,769 | $21.0K | 0.00% | −17,578−48.4% | Reduced |
| CIBC World Markets Inc. | 18,206 | $20.0K | 0.00% | +2,660+17.1% | Added |
| Fulton Breakefield Broenniman LLC | 17,750 | $20.0K | 0.00% | +5,000+39.2% | Added |
| JSF Financial, LLC | 18,215 | $20.0K | 0.01% | +18,215 | New |
| Raymond James & Associates | 17,032 | $19.0K | 0.00% | +17,032 | New |
| Federation des caisses Desjardins du Quebec | 16,559 | $18.3K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 15,337 | $18.0K | 0.00% | −78,979−83.7% | Reduced |
| Beacon Pointe Advisors, LLC | 16,567 | $18.0K | 0.00% | +16,567 | New |
| Strategic Blueprint, LLC | 16,000 | $18.0K | 0.00% | +16,000 | New |
| Metropolitan Life Insurance Co | 15,727 | $17.5K | 0.00% | −61,625−79.7% | Reduced |
| Xponance, Inc. | 15,230 | $17.0K | 0.00% | −1,256−7.6% | Reduced |
| Veritable, L.P. | 15,100 | $17.0K | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 13,201 | $15.0K | 0.00% | 00.0% | Unchanged |
| Exchange Traded Concepts, LLC | 13,553 | $15.0K | 0.00% | +13,553 | New |
| Sawtooth Solutions, LLC | 13,315 | $15.0K | 0.00% | +13,315 | New |