Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Definium Therapeutics, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 104
- +7 vs. Q3 2022
- Shares held
- 5.06M
- −640.9K (−11.2%) vs. Q3 2022
- Total value
- $11.1M
- −$8.73M (−44.0%) vs. Q3 2022
- New holders
- 29
- 19 more added
- Sold out
- 22
- 24 more reduced
4 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alyeska Investment Group, L.P. | 1,100,000 | $2.42M | 0.03% | +100,000+10.0% | Added |
| Vanguard Group Inc | 594,394 | $1.31M | 0.00% | +581,486+4,504.8% | Added |
| Merit Financial Group, LLC | 540,287 | $1.19M | 0.04% | −540,287−50.0% | Reduced |
| BlackRock Inc. | 451,992 | $994.4K | 0.00% | +421,478+1,381.3% | Added |
| Geode Capital Management, LLC | 281,671 | $619.0K | 0.00% | +281,671 | New |
| Millennium Management LLC | 249,450 | $549.0K | 0.00% | +94,551+61.0% | Added |
| Busey Wealth Management | 244,347 | $537.6K | 0.02% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 181,467 | $399.2K | 0.00% | +181,467 | New |
| Susquehanna International Group, LLP | 165,795 | $364.7K | 0.00% | +165,795 | New |
| AdvisorShares Investments LLC | 113,437 | $249.6K | 0.07% | +53,485+89.2% | Added |
| Data Collective IV GP, LLC | 100,350 | $220.8K | 0.23% | −1,404,898−93.3% | Reduced |
| State Street Corp | 98,901 | $217.6K | 0.00% | +44,994+83.5% | Added |
| Telemetry Investments, L.L.C. | 96,000 | $211.0K | 0.49% | −9,500−9.0% | Reduced |
| Goldman Sachs Group Inc | 86,861 | $191.1K | 0.00% | +71,056+449.6% | Added |
| Citadel Advisors LLC | 76,388 | $168.1K | 0.00% | −10,549−12.1% | Reduced |
| Virtu Financial LLC | 70,157 | $154.0K | 0.02% | +34,247+95.4% | Added |
| Cubist Systematic Strategies, LLC | 61,769 | $135.9K | 0.00% | +17,518+39.6% | Added |
| Northern Trust Corp | 55,688 | $122.5K | 0.00% | +55,688 | New |
| Morgan Stanley | 52,955 | $116.5K | 0.00% | +26,583+100.8% | Added |
| Kestra Private Wealth Services, LLC | 51,472 | $113.2K | 0.01% | +1,000+2.0% | Added |
| Fore Capital, LLC | 47,999 | $105.6K | 0.18% | 00.0% | Unchanged |
| Occudo Quantitative Strategies LP | 41,864 | $92.1K | 0.01% | +41,864 | New |
| Prelude Capital Management, LLC | 38,200 | $84.0K | 0.01% | +38,200 | New |
| Aristides Capital LLC | 37,625 | $82.8K | 0.05% | +37,625 | New |
| Two Sigma Investments, LP | 33,872 | $74.5K | 0.00% | +33,872 | New |
| Bank of New York Mellon Corp | 24,767 | $54.5K | 0.00% | +24,767 | New |
| Two Sigma Securities, LLC | 24,099 | $53.0K | 0.01% | +24,099 | New |
| LPL Financial LLC | 18,555 | $40.8K | 0.00% | +668+3.7% | Added |
| UBS Group AG | 15,536 | $34.2K | 0.00% | −6,711−30.2% | Reduced |
| Exchange Traded Concepts, LLC | 14,955 | $32.9K | 0.00% | +10,492+235.1% | Added |
| Bank of America Corp | 13,086 | $28.8K | 0.00% | −42,449−76.4% | Reduced |
| Freestone Capital Holdings, LLC | 11,497 | $25.3K | 0.00% | +11,497 | New |
| Schonfeld Strategic Advisors LLC | 10,400 | $22.9K | 0.00% | +10,400 | New |
| Deutsche Bank AG | 10,389 | $22.9K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 10,076 | $22.2K | 0.00% | +10,076 | New |
| Barclays PLC | 9,147 | $20.1K | 0.00% | −78−0.8% | Reduced |
| Royal Bank of Canada | 5,211 | $11.0K | 0.00% | −8,233−61.2% | Reduced |
| Advisor Group Holdings, Inc. | 4,099 | $9.40K | 0.00% | +2,308+128.9% | Added |
| Crewe Advisors LLC | 1,999 | $4.40K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 1,866 | $4.00K | 0.00% | −1,968−51.3% | Reduced |
| National Bank of Canada | 1,767 | $3.85K | 0.00% | +25+1.4% | Added |
| TD Waterhouse Canada Inc. | 1,028 | $3.06K | 0.00% | +373+56.9% | Added |
| Simplex Trading, LLC | 1,374 | $3.00K | 0.00% | −33,023−96.0% | Reduced |
| Tower Research Capital LLC (TRC) | 1,311 | $3.00K | 0.00% | −48−3.5% | Reduced |
| Legal & General Group Plc | 1,025 | $2.25K | 0.00% | −2,957−74.3% | Reduced |
| Federation des caisses Desjardins du Quebec | 987 | $2.17K | 0.00% | 00.0% | Unchanged |
| Accurate Wealth Management, LLC | 649 | $1.80K | 0.00% | +649 | New |
| Edmond de Rothschild Holding S.A. | 666 | $1.47K | 0.00% | 00.0% | Unchanged |
| Column Capital Advisors, LLC | 610 | $1.34K | 0.00% | +610 | New |
| Belpointe Asset Management LLC | 590 | $1.30K | 0.00% | +590 | New |
| Money Concepts Capital Corp | 500 | $1.10K | 0.00% | +500 | New |
| Tortoise Investment Management, LLC | 400 | $880 | 0.00% | −400−50.0% | Reduced |
| Albion Financial Group | 323 | $711 | 0.00% | 00.0% | Unchanged |
| Emfo, LLC | 300 | $660 | 0.00% | −300−50.0% | Reduced |
| Wells Fargo & Company | 225 | $495 | 0.00% | +225 | New |
| Kistler-Tiffany Companies, LLC | 218 | $480 | 0.00% | 00.0% | Unchanged |
| Tradewinds Capital Management, LLC | 154 | $339 | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 143 | $315 | 0.00% | 00.0% | Unchanged |
| Burleson & Company, LLC | 86 | $189 | 0.00% | −86−50.0% | Reduced |
| FMR LLC | 80 | $176 | 0.00% | +67+515.4% | Added |
| Allworth Financial LP | 66 | $145 | 0.00% | −16−19.5% | Reduced |
| Clearview Wealth Advisors LLC | 66 | $145 | 0.00% | 00.0% | Unchanged |
| Hollencrest Capital Management | 66 | $145 | 0.00% | +66 | New |
| HighMark Wealth Management LLC | 55 | $121 | 0.00% | −59−51.8% | Reduced |
| Citigroup Inc | 36 | $79 | 0.00% | −6,255−99.4% | Reduced |
| Plante Moran Financial Advisors, LLC | 36 | $79 | 0.00% | 00.0% | Unchanged |
| Horan Securities, Inc. | 35 | $77 | 0.00% | 00.0% | Unchanged |
| North Star Investment Management Corp. | 33 | $73 | 0.00% | 00.0% | Unchanged |
| FinTrust Capital Advisors, LLC | 33 | $73 | 0.00% | 00.0% | Unchanged |
| Glen Eagle Advisors, LLC | 30 | $66 | 0.00% | −22−42.3% | Reduced |
| Robbins Farley LLC | 28 | $62 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 28 | $62 | 0.00% | +28 | New |
| Heritage Wealth Management, LLC | 26 | $57 | 0.00% | +7+36.8% | Added |
| Advisory Services Network, LLC | 25 | $55 | 0.00% | +25 | New |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 24 | $52 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 22 | $48 | 0.00% | −644−96.7% | Reduced |
| Pacifica Partners Inc. | 20 | $45 | 0.00% | 00.0% | Unchanged |
| Gradient Investments LLC | 20 | $44 | 0.00% | −20−50.0% | Reduced |
| NewSquare Capital LLC | 17 | $37 | 0.00% | +17 | New |
| CoreCap Advisors, LLC | 17 | $37 | 0.00% | +17 | New |
| JJJ Advisors Inc. | 10 | $31 | 0.00% | 00.0% | Unchanged |
| SJS Investment Consulting Inc. | 14 | $31 | 0.00% | +12+600.0% | Added |
| Focused Wealth Management, Inc | 10 | $22 | 0.00% | 00.0% | Unchanged |
| Sargent Bickham Lagudis LLC | 10 | $22 | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 10 | $22 | 0.00% | +10 | New |
| CNB Bank | 10 | $22 | 0.00% | +10 | New |
| AdvisorNet Financial, Inc | 3 | $7 | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 2 | $4 | 0.00% | −2−50.0% | Reduced |
| Huntington National Bank | 1 | $1 | 0.00% | −2,000−100.0% | Reduced |
| Front Row Advisors LLC | 133 | $0 | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 16 | $0 | 0.00% | 00.0% | Unchanged |
| Arrow Financial Corp | 66 | $0 | 0.00% | 00.0% | Unchanged |
| Cutler Group LP | 86 | $0 | 0.00% | 00.0% | Unchanged |
| Westside Investment Management, Inc. | 66 | $0 | 0.00% | 00.0% | Unchanged |
| PrairieView Partners, LLC | 4 | $0 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 148 | $0 | 0.00% | 00.0% | Unchanged |
| Baldrige Asset Management LLC | 133 | $0 | 0.00% | 00.0% | Unchanged |
| Princeton Global Asset Management LLC | 100 | $0 | 0.00% | 00.0% | Unchanged |
| TSFG, LLC | 24 | $0 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 15 | $0 | 0.00% | +15 | New |