Skip to main content

Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2023

Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
89
−10 vs. Q4 2022
Shares held
3.94M
−1.02M (−20.6%) vs. Q4 2022
Total value
$12.6M
+$1.63M (+14.9%) vs. Q4 2022
New holders
9
16 more added
Sold out
19
22 more reduced

5 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 89 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ1 2023: $12.6M
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2022.

Institutions holding DFTX in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Alyeska Investment Group, L.P.1,042,639$3.31M0.03%−57,361−5.2%Reduced
Vanguard Group Inc573,939$1.82M0.00%−20,455−3.4%Reduced
BlackRock Inc.451,992$1.43M0.00%00.0%Unchanged
Geode Capital Management, LLC340,055$1.08M0.00%+58,384+20.7%Added
Busey Wealth Management244,347$774.6K0.03%00.0%Unchanged
Susquehanna International Group, LLP232,027$735.5K0.00%+66,232+39.9%Added
Charles Schwab Investment Management Inc178,950$567.3K0.00%−2,517−1.4%Reduced
Two Sigma Investments, LP168,185$533.1K0.00%+134,313+396.5%Added
State Street Corp122,000$386.7K0.00%+23,099+23.4%Added
Data Collective IV GP, LLC100,350$318.1K0.34%00.0%Unchanged
AdvisorShares Investments LLC93,310$295.8K0.09%−20,127−17.7%Reduced
Northern Trust Corp58,391$185.1K0.00%+2,703+4.9%Added
Renaissance Technologies LLC55,786$177.0K0.00%+55,786New
Kestra Private Wealth Services, LLC51,339$162.7K0.01%−133−0.3%Reduced
Morgan Stanley37,041$117.4K0.00%−15,914−30.1%Reduced
Bank of New York Mellon Corp34,276$108.7K0.00%+9,509+38.4%Added
LPL Financial LLC20,832$66.0K0.00%+2,277+12.3%Added
Man Group plc–$59.0K0.00%–New
Goldman Sachs Group Inc15,816$50.1K0.00%−71,045−81.8%Reduced
Citadel Advisors LLC14,790$46.9K0.00%−61,598−80.6%Reduced
Federation des caisses Desjardins du Quebec14,187$44.7K0.00%+13,200+1,337.4%Added
Prelude Capital Management, LLC12,400$39.3K0.00%−25,800−67.5%Reduced
Freestone Capital Holdings, LLC11,497$36.4K0.00%00.0%Unchanged
UBS Group AG9,802$31.1K0.00%−5,734−36.9%Reduced
Barclays PLC9,147$29.0K0.00%00.0%Unchanged
North Star Investment Management Corp.9,125$28.9K0.00%+9,092+27,551.5%Added
Bank of America Corp8,551$27.1K0.00%−4,535−34.7%Reduced
Deutsche Bank AG8,021$25.4K0.00%−2,368−22.8%Reduced
Royal Bank of Canada4,650$14.0K0.00%−561−10.8%Reduced
Advisor Group Holdings, Inc.4,074$12.9K0.00%−25−0.6%Reduced
Tower Research Capital LLC (TRC)3,103$10.0K0.00%+1,792+136.7%Added
Crewe Advisors LLC1,999$6.34K0.00%00.0%Unchanged
CWM, LLC1,863$6.00K0.00%−3−0.2%Reduced
National Bank of Canada1,567$4.89K0.00%−200−11.3%Reduced
TD Waterhouse Canada Inc.735$2.54K0.00%−293−28.5%Reduced
Edmond de Rothschild Holding S.A.666$2.11K0.00%00.0%Unchanged
Column Capital Advisors, LLC610$1.93K0.00%00.0%Unchanged
Belpointe Asset Management LLC604$1.91K0.00%+14+2.4%Added
Parallel Advisors, LLC543$1.72K0.00%+400+279.7%Added
Tortoise Investment Management, LLC400$1.27K0.00%00.0%Unchanged
Albion Financial Group323$1.02K0.00%00.0%Unchanged
Emfo, LLC300$9510.00%00.0%Unchanged
Wells Fargo & Company228$7230.00%+3+1.3%Added
Kistler-Tiffany Companies, LLC218$6920.00%00.0%Unchanged
FMR LLC148$4690.00%+68+85.0%Added
Princeton Global Asset Management LLC100$3170.00%00.0%Unchanged
Farther Finance Advisors, LLC100$3170.00%+100New
Allworth Financial LP66$2100.00%00.0%Unchanged
Hollencrest Capital Management66$2090.00%00.0%Unchanged
Clearview Wealth Advisors LLC66$2090.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co66$2090.00%+44+200.0%Added
Arrow Financial Corp66$2090.00%00.0%Unchanged
Westside Investment Management, Inc.66$2090.00%00.0%Unchanged
US Bancorp66$2090.00%+66New
Tradewinds Capital Management, LLC53$1690.00%−101−65.6%Reduced
Gradient Investments LLC38$1200.00%+18+90.0%Added
Plante Moran Financial Advisors, LLC36$1140.00%00.0%Unchanged
Chesapeake Asset Management LLC33$1040.00%+33New
Glen Eagle Advisors, LLC30$950.00%00.0%Unchanged
HighMark Wealth Management LLC29$920.00%−26−47.3%Reduced
SRS Capital Advisors, Inc.28$890.00%00.0%Unchanged
Robbins Farley LLC28$890.00%00.0%Unchanged
Nelson, Van Denburg & Campbell Wealth Management Group, LLC24$760.00%00.0%Unchanged
FinTrust Capital Advisors, LLC33$730.00%00.0%Unchanged
Pacifica Partners Inc.20$580.00%00.0%Unchanged
NewSquare Capital LLC17$540.00%00.0%Unchanged
GWM Advisors LLC15$480.00%00.0%Unchanged
SJS Investment Consulting Inc.14$450.00%00.0%Unchanged
JJJ Advisors Inc.10$320.00%00.0%Unchanged
Harbour Investments, Inc.10$320.00%00.0%Unchanged
Focused Wealth Management, Inc10$320.00%00.0%Unchanged
CNB Bank10$320.00%00.0%Unchanged
Advisory Services Network, LLC9$290.00%−16−64.0%Reduced
Belmont Capital, LLC6$190.00%00.0%Unchanged
Strategic Investment Solutions, Inc.6$190.00%+6New
Grey Fox Wealth Advisors, LLC6$190.00%+6New
AdvisorNet Financial, Inc3$100.00%00.0%Unchanged
Horan Securities, Inc.2$60.00%−33−94.3%Reduced
Signaturefd, LLC2$60.00%00.0%Unchanged
Huntington National Bank1$10.00%00.0%Unchanged
JPMorgan Chase & Co16$00.00%00.0%Unchanged
Cutler Group LP86$00.00%00.0%Unchanged
PrairieView Partners, LLC4$00.00%00.0%Unchanged
Front Row Advisors LLC133$00.00%00.0%Unchanged
Baldrige Asset Management LLC133$00.00%00.0%Unchanged
TSFG, LLC24$00.00%00.0%Unchanged
Ogorek Anthony Joseph16$00.00%+16New
VitalStone Financial, LLC350$00.00%+350New
IFP Advisors, Inc30––−203−87.1%Reduced
Merit Financial Group, LLC0$00.00%−540,287−100.0%Sold out
Millennium Management LLC0$00.00%−249,450−100.0%Sold out
Virtu Financial LLC0$00.00%−70,157−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−61,769−100.0%Sold out
Fore Capital, LLC0$00.00%−47,999−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−41,864−100.0%Sold out
Aristides Capital LLC0$00.00%−37,625−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−24,099−100.0%Sold out
Exchange Traded Concepts, LLC0$00.00%−14,955−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−10,400−100.0%Sold out
Engineers Gate Manager LP0$00.00%−10,076−100.0%Sold out