Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 135
- +33 vs. Q4 2023
- Shares held
- 34.8M
- +29.9M (+612.9%) vs. Q4 2023
- Total value
- $327.2M
- +$309.4M (+1,731.0%) vs. Q4 2023
- New holders
- 46
- 31 more added
- Sold out
- 13
- 17 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Deep Track Capital, LP | 6,666,667 | $62.7M | 1.80% | +6,666,667 | New |
| Commodore Capital LP | 5,833,333 | $54.8M | 3.67% | +5,833,333 | New |
| Driehaus Capital Management LLC | 2,547,545 | $23.9M | 0.24% | +2,547,545 | New |
| Octagon Capital Advisors LP | 2,153,000 | $20.2M | 2.46% | +2,153,000 | New |
| Great Point Partners LLC | 2,000,000 | $18.8M | 2.93% | +2,000,000 | New |
| Marshall Wace, LLP | 1,998,544 | $18.8M | 0.03% | +1,998,544 | New |
| Blackstone Group Inc. | 1,249,875 | $11.7M | 0.05% | +1,249,875 | New |
| Ally Bridge Group (NY) LLC | 1,001,452 | $9.41M | 5.23% | +1,001,452 | New |
| Woodline Partners LP | 1,000,579 | $9.41M | 0.09% | +1,000,579 | New |
| Janus Henderson Group PLC | 955,678 | $8.96M | 0.00% | +955,678 | New |
| AWM Investment Company, Inc. | 833,000 | $7.83M | 1.03% | +833,000 | New |
| BlackRock Inc. | 794,312 | $7.47M | 0.00% | +243,695+44.3% | Added |
| Soleus Capital Management, L.P. | 750,237 | $7.05M | 0.62% | +750,237 | New |
| Two Sigma Investments, LP | 712,238 | $6.70M | 0.02% | +573,142+412.0% | Added |
| Vanguard Group Inc | 562,921 | $5.29M | 0.00% | −4,964−0.9% | Reduced |
| Goldman Sachs Group Inc | 408,000 | $3.84M | 0.00% | +296,069+264.5% | Added |
| Geode Capital Management, LLC | 389,404 | $3.66M | 0.00% | +11,489+3.0% | Added |
| Millennium Management LLC | 388,202 | $3.65M | 0.00% | +280,363+260.0% | Added |
| Tri Locum Partners LP | 379,596 | $3.57M | 1.24% | +379,596 | New |
| Jane Street Group, LLC | 372,459 | $3.50M | 0.00% | +262,796+239.6% | Added |
| Tang Capital Management LLC | 300,000 | $2.82M | 0.29% | +300,000 | New |
| Ikarian Capital, LLC | 297,481 | $2.80M | 0.76% | −302,519−50.4% | Reduced |
| Susquehanna International Group, LLP | 269,596 | $2.53M | 0.00% | +39,545+17.2% | Added |
| HRT Financial LP | 207,253 | $1.95M | 0.01% | +207,253 | New |
| Charles Schwab Investment Management Inc | 197,214 | $1.85M | 0.00% | +5,340+2.8% | Added |
| D. E. Shaw & Co., Inc. | 183,029 | $1.72M | 0.00% | +183,029 | New |
| Toroso Investments, LLC | 180,600 | $1.70M | 0.03% | +180,600 | New |
| Moloney Securities Asset Management, LLC | 161,961 | $1.52M | 0.23% | +92,450+133.0% | Added |
| State Street Corp | 118,904 | $1.12M | 0.00% | −3,200−2.6% | Reduced |
| Qube Research & Technologies Ltd | 116,327 | $1.09M | 0.00% | +22,678+24.2% | Added |
| Man Group plc | 112,177 | $1.05M | 0.00% | +112,177 | New |
| Citigroup Inc | 111,066 | $1.04M | 0.00% | −308−0.3% | Reduced |
| Morgan Stanley | 110,962 | $1.04M | 0.00% | +88,101+385.4% | Added |
| AdvisorShares Investments LLC | 109,507 | $1.03M | 0.17% | −3,267−2.9% | Reduced |
| Data Collective IV GP, LLC | 100,350 | $943.3K | 0.82% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 84,624 | $795.5K | 0.02% | −62,036−42.3% | Reduced |
| Northern Trust Corp | 65,549 | $616.2K | 0.00% | +3,486+5.6% | Added |
| Squarepoint Ops LLC | 57,650 | $541.9K | 0.00% | +57,650 | New |
| Citadel Advisors LLC | 57,320 | $538.8K | 0.00% | +56,235+5,182.9% | Added |
| Wellington Management Group LLP | 55,065 | $517.6K | 0.00% | +55,065 | New |
| Simplex Trading, LLC | 54,848 | $515.0K | 0.02% | +45,871+511.0% | Added |
| Scotia Capital Inc. | 53,951 | $505.9K | 0.00% | −67,805−55.7% | Reduced |
| Kestra Private Wealth Services, LLC | 51,339 | $482.6K | 0.01% | 00.0% | Unchanged |
| LPL Financial LLC | 43,727 | $411.0K | 0.00% | +8,497+24.1% | Added |
| Bank of New York Mellon Corp | 42,992 | $404.1K | 0.00% | −19,254−30.9% | Reduced |
| Wolverine Trading, LLC | 41,296 | $388.2K | 0.00% | +31,059+303.4% | Added |
| Royal Bank of Canada | 40,619 | $381.0K | 0.00% | +35,234+654.3% | Added |
| Group One Trading, L.P. | 36,358 | $341.8K | 0.01% | −74,070−67.1% | Reduced |
| Laurion Capital Management LP | 30,426 | $286.0K | 0.01% | +30,426 | New |
| Caxton Corp | 29,065 | $273.2K | 1.56% | +29,065 | New |
| Cubist Systematic Strategies, LLC | 28,618 | $269.0K | 0.00% | +28,618 | New |
| Bank of America Corp | 26,182 | $246.1K | 0.00% | −5,860−18.3% | Reduced |
| Virtu Financial LLC | 25,440 | $239.0K | 0.02% | +25,440 | New |
| GTS Securities LLC | 24,921 | $234.3K | 0.01% | +24,921 | New |
| Commonwealth Equity Services, LLC | 24,852 | $234.0K | 0.00% | +8,322+50.3% | Added |
| FMR LLC | 24,577 | $231.0K | 0.00% | +770+3.2% | Added |
| UBS Group AG | 24,384 | $229.2K | 0.00% | +23,981+5,950.6% | Added |
| Rathbone Brothers plc | 24,200 | $227.5K | 0.00% | −800−3.2% | Reduced |
| Bailard, Inc. | 24,100 | $226.5K | 0.01% | +6,800+39.3% | Added |
| Y-Intercept (Hong Kong) Ltd | 23,316 | $219.2K | 0.02% | +6,463+38.3% | Added |
| Two Sigma Advisers, LP | 21,917 | $206.0K | 0.00% | +21,917 | New |
| Mitchell McLeod Pugh & Williams Inc | 20,000 | $188.0K | 0.05% | 00.0% | Unchanged |
| Sequoia Financial Advisors, LLC | 17,912 | $168.4K | 0.00% | +17,912 | New |
| LMR Partners LLP | 16,374 | $153.9K | 0.00% | +16,374 | New |
| Chiron Investment Management, LLC | 15,932 | $149.8K | 0.06% | +15,932 | New |
| Federation des caisses Desjardins du Quebec | 14,121 | $149.1K | 0.00% | −66−0.5% | Reduced |
| PEAK6 Investments LLC | 15,454 | $145.3K | 0.01% | +15,454 | New |
| Mercer Global Advisors Inc | 14,928 | $140.0K | 0.00% | +14,928 | New |
| Raymond James Financial Services Advisors, Inc. | 13,762 | $129.4K | 0.00% | +13,762 | New |
| Polymer Capital Management (HK) LTD | 11,926 | $112.1K | 0.03% | +11,926 | New |
| Blair William & Co | 11,341 | $106.6K | 0.00% | +11,341 | New |
| Brevan Howard Capital Management LP | 10,649 | $100.1K | 0.01% | +10,649 | New |
| Thrivent Financial for Lutherans | 10,027 | $94.0K | 0.00% | +10,027 | New |
| Barclays PLC | 9,147 | $86.0K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 4,537 | $59.9K | 0.00% | +3,880+590.6% | Added |
| Tower Research Capital LLC (TRC) | 5,763 | $54.2K | 0.00% | −57−1.0% | Reduced |
| Deutsche Bank AG | 5,613 | $52.8K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 3,741 | $35.2K | 0.00% | +464+14.2% | Added |
| JPMorgan Chase & Co | 3,516 | $33.0K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 2,583 | $24.3K | 0.00% | +2,324+897.3% | Added |
| North Star Investment Management Corp. | 2,150 | $20.2K | 0.00% | +2,150 | New |
| Crewe Advisors LLC | 1,999 | $18.8K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 1,742 | $16.1K | 0.00% | +75+4.5% | Added |
| CWM, LLC | 1,538 | $14.0K | 0.00% | +270+21.3% | Added |
| Symmetry Peak Management LLC | 800 | $7.52K | 0.15% | +800 | New |
| NBC Securities, Inc. | 600 | $5.00K | 0.00% | +600 | New |
| CIBC Private Wealth Group, LLC | 434 | $4.13K | 0.00% | +434 | New |
| NVWM, LLC | 416 | $3.91K | 0.00% | 00.0% | Unchanged |
| Tortoise Investment Management, LLC | 400 | $3.76K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 368 | $3.46K | 0.00% | +352+2,200.0% | Added |
| Emfo, LLC | 300 | $2.82K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 279 | $2.62K | 0.00% | +179+179.0% | Added |
| Federated Hermes, Inc. | 247 | $2.32K | 0.00% | +247 | New |
| Cutler Group LP | 300 | $2.00K | 0.00% | +171+132.6% | Added |
| GWM Advisors LLC | 148 | $1.39K | 0.00% | 00.0% | Unchanged |
| Albion Financial Group | 132 | $1.24K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 100 | $952 | 0.00% | 00.0% | Unchanged |
| Fairman Group, LLC | 85 | $799 | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 68 | $639 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 66 | $621 | 0.00% | 00.0% | Unchanged |