Definium Therapeutics, Inc.

DFTX

Exchange: Nasdaq
Industry: Medicinal Chemicals & Botanical Products
SEC CIK: 0001813814

SEC filings (opens in a new tab)

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

Q1 2024 vs. Q4 2023

How the institutions holding Definium Therapeutics, Inc. changed between Q4 2023 and Q1 2024.

All holders in Q1 2024 All holders in Q4 2023

13F holders of DFTX: Q4 2023 compared with Q1 2024
Measure	Q4 2023	Of which not filed for Q1 2024	Q1 2024	Change
Holders	104	2	135	+33
Shares	4.88M	7	34.8M	+29.9M (+612.9%)
Value	$17.9M	$26	$327.2M	+$309.4M (+1,731.0%)

2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so the changes leave them out.

New holders (46)

Institutions that held Definium Therapeutics, Inc. at the end of Q1 2024 but not at the end of Q4 2023.

Institutions new to DFTX in Q1 2024
Institution	Shares	Value	% of portfolio
Deep Track Capital, LP	6,666,667	$62.7M	1.80%
Commodore Capital LP	5,833,333	$54.8M	3.67%
Driehaus Capital Management LLC	2,547,545	$23.9M	0.24%
Octagon Capital Advisors LP	2,153,000	$20.2M	2.46%
Great Point Partners LLC	2,000,000	$18.8M	2.93%
Marshall Wace, LLP	1,998,544	$18.8M	0.03%
Blackstone Group Inc.	1,249,875	$11.7M	0.05%
Ally Bridge Group (NY) LLC	1,001,452	$9.41M	5.23%
Woodline Partners LP	1,000,579	$9.41M	0.09%
Janus Henderson Group PLC	955,678	$8.96M	0.00%
AWM Investment Company, Inc.	833,000	$7.83M	1.03%
Soleus Capital Management, L.P.	750,237	$7.05M	0.62%
Tri Locum Partners LP	379,596	$3.57M	1.24%
Tang Capital Management LLC	300,000	$2.82M	0.29%
HRT Financial LP	207,253	$1.95M	0.01%
D. E. Shaw & Co., Inc.	183,029	$1.72M	0.00%
Toroso Investments, LLC	180,600	$1.70M	0.03%
Man Group plc	112,177	$1.05M	0.00%
Squarepoint Ops LLC	57,650	$541.9K	0.00%
Wellington Management Group LLP	55,065	$517.6K	0.00%
Laurion Capital Management LP	30,426	$286.0K	0.01%
Caxton Corp	29,065	$273.2K	1.56%
Cubist Systematic Strategies, LLC	28,618	$269.0K	0.00%
Virtu Financial LLC	25,440	$239.0K	0.02%
GTS Securities LLC	24,921	$234.3K	0.01%
Two Sigma Advisers, LP	21,917	$206.0K	0.00%
Sequoia Financial Advisors, LLC	17,912	$168.4K	0.00%
LMR Partners LLP	16,374	$153.9K	0.00%
Chiron Investment Management, LLC	15,932	$149.8K	0.06%
PEAK6 Investments LLC	15,454	$145.3K	0.01%
Mercer Global Advisors Inc	14,928	$140.0K	0.00%
Raymond James Financial Services Advisors, Inc.	13,762	$129.4K	0.00%
Polymer Capital Management (HK) LTD	11,926	$112.1K	0.03%
Blair William & Co	11,341	$106.6K	0.00%
Brevan Howard Capital Management LP	10,649	$100.1K	0.01%
Thrivent Financial for Lutherans	10,027	$94.0K	0.00%
North Star Investment Management Corp.	2,150	$20.2K	0.00%
Symmetry Peak Management LLC	800	$7.52K	0.15%
NBC Securities, Inc.	600	$5.00K	0.00%
CIBC Private Wealth Group, LLC	434	$4.13K	0.00%
Federated Hermes, Inc.	247	$2.32K	0.00%
Continuum Advisory, LLC	20	$182	0.00%
CoreCap Advisors, LLC	15	$141	0.00%
Macquarie Group Ltd	3,779	$36	0.00%
Sofos Investments, Inc.	2	$19	0.00%
SageView Advisory Group, LLC	2,648	–	–

Sold out (13)

Institutions that held Definium Therapeutics, Inc. at the end of Q4 2023 and filed for Q1 2024 without it.

Institutions that sold out of DFTX in Q1 2024
Institution	Shares, Q4 2023	Value, Q4 2023
Busey Wealth Management	156,320	$572.1K
Cresset Asset Management, LLC	154,498	$565.5K
Cornercap Investment Counsel Inc	56,957	$208.5K
Jump Financial, LLC	36,826	$134.8K
XTX Topco Ltd	23,935	$87.6K
Regal Investment Advisors LLC	14,556	$53.3K
Edmond de Rothschild Holding S.A.	666	$2.44K
Householder Group Estate & Retirement Specialist, LLC	600	$2.00K
Princeton Global Asset Management LLC	100	$366
US Bancorp	66	$242
Focused Wealth Management, Inc	10	$37
Advisory Services Network, LLC	9	$33
AdvisorNet Financial, Inc	3	$11

Not filed for Q1 2024 yet (2)

Institutions that held Definium Therapeutics, Inc. at the end of Q4 2023 and haven't filed a 13F for Q1 2024. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding DFTX in Q4 2023 that haven't filed for Q1 2024
Institution	Shares, Q4 2023	Value, Q4 2023
Strategic Investment Solutions, Inc.	6	$22
Coppell Advisory Solutions LLC	1	$4