Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Definium Therapeutics, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 104
- +12 vs. Q3 2023
- Shares held
- 4.88M
- +1.01M (+26.0%) vs. Q3 2023
- Total value
- $17.9M
- +$5.74M (+47.3%) vs. Q3 2023
- New holders
- 21
- 22 more added
- Sold out
- 9
- 20 more reduced
1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ikarian Capital, LLC | 600,000 | $2.20M | 0.60% | +600,000 | New |
| Vanguard Group Inc | 567,885 | $2.08M | 0.00% | 00.0% | Unchanged |
| BlackRock Inc. | 550,617 | $2.02M | 0.00% | +1,536+0.3% | Added |
| Geode Capital Management, LLC | 377,915 | $1.38M | 0.00% | +6,602+1.8% | Added |
| Susquehanna International Group, LLP | 230,051 | $842.0K | 0.00% | +36,169+18.7% | Added |
| Charles Schwab Investment Management Inc | 191,874 | $702.3K | 0.00% | +3,338+1.8% | Added |
| Busey Wealth Management | 156,320 | $572.1K | 0.02% | −50,000−24.2% | Reduced |
| Cresset Asset Management, LLC | 154,498 | $565.5K | 0.00% | −2,426−1.5% | Reduced |
| Boothbay Fund Management, LLC | 146,660 | $536.8K | 0.02% | +146,660 | New |
| Two Sigma Investments, LP | 139,096 | $509.1K | 0.00% | −18,343−11.7% | Reduced |
| State Street Corp | 122,104 | $446.9K | 0.00% | +104+0.1% | Added |
| Scotia Capital Inc. | 121,756 | $441.1K | 0.00% | +121,756 | New |
| AdvisorShares Investments LLC | 112,774 | $412.8K | 0.10% | −4,637−3.9% | Reduced |
| Goldman Sachs Group Inc | 111,931 | $409.7K | 0.00% | +85,025+316.0% | Added |
| Citigroup Inc | 111,374 | $407.6K | 0.00% | +24,279+27.9% | Added |
| Group One Trading, L.P. | 110,428 | $404.2K | 0.01% | −24,149−17.9% | Reduced |
| Jane Street Group, LLC | 109,663 | $401.4K | 0.00% | +93,079+561.3% | Added |
| Millennium Management LLC | 107,839 | $394.7K | 0.00% | −129,636−54.6% | Reduced |
| Data Collective IV GP, LLC | 100,350 | $367.3K | 0.30% | +10.0% | Added |
| Qube Research & Technologies Ltd | 93,649 | $342.8K | 0.00% | +84,644+940.0% | Added |
| Moloney Securities Asset Management, LLC | 69,511 | $254.4K | 0.04% | +69,511 | New |
| Bank of New York Mellon Corp | 62,246 | $227.8K | 0.00% | −687−1.1% | Reduced |
| Northern Trust Corp | 62,063 | $227.2K | 0.00% | −193−0.3% | Reduced |
| Cornercap Investment Counsel Inc | 56,957 | $208.5K | 0.03% | 00.0% | Unchanged |
| Kestra Private Wealth Services, LLC | 51,339 | $187.9K | 0.00% | 00.0% | Unchanged |
| Jump Financial, LLC | 36,826 | $134.8K | 0.00% | +2,826+8.3% | Added |
| LPL Financial LLC | 35,230 | $128.9K | 0.00% | +14,079+66.6% | Added |
| Bank of America Corp | 32,042 | $117.3K | 0.00% | +17,103+114.5% | Added |
| Rathbone Brothers plc | 25,000 | $91.5K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 23,935 | $87.6K | 0.02% | +23,935 | New |
| FMR LLC | 23,807 | $87.1K | 0.00% | +6,551+38.0% | Added |
| Morgan Stanley | 22,861 | $83.7K | 0.00% | −12,741−35.8% | Reduced |
| Mitchell McLeod Pugh & Williams Inc | 20,000 | $73.2K | 0.02% | +20,000 | New |
| Bailard, Inc. | 17,300 | $63.3K | 0.00% | +17,300 | New |
| Y-Intercept (Hong Kong) Ltd | 16,853 | $61.7K | 0.01% | +16,853 | New |
| Commonwealth Equity Services, LLC | 16,530 | $61.0K | 0.00% | −421−2.5% | Reduced |
| Regal Investment Advisors LLC | 14,556 | $53.3K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 14,187 | $51.8K | 0.00% | 00.0% | Unchanged |
| Wolverine Trading, LLC | 10,237 | $37.5K | 0.00% | −4,381−30.0% | Reduced |
| Barclays PLC | 9,147 | $33.5K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 8,977 | $32.0K | 0.00% | −758−7.8% | Reduced |
| Tower Research Capital LLC (TRC) | 5,820 | $21.3K | 0.00% | +5,687+4,275.9% | Added |
| Deutsche Bank AG | 5,613 | $20.5K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 5,385 | $20.0K | 0.00% | +939+21.1% | Added |
| JPMorgan Chase & Co | 3,516 | $12.9K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 3,277 | $12.0K | 0.00% | −1,638−33.3% | Reduced |
| Toronto Dominion Bank | 2,157 | $7.89K | 0.00% | −400−15.6% | Reduced |
| Crewe Advisors LLC | 1,999 | $7.32K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 1,667 | $6.00K | 0.00% | +33+2.0% | Added |
| CWM, LLC | 1,268 | $5.00K | 0.00% | −595−31.9% | Reduced |
| Citadel Advisors LLC | 1,085 | $3.97K | 0.00% | −60,603−98.2% | Reduced |
| TD Waterhouse Canada Inc. | 657 | $2.92K | 0.00% | −110−14.3% | Reduced |
| Edmond de Rothschild Holding S.A. | 666 | $2.44K | 0.00% | 00.0% | Unchanged |
| Householder Group Estate & Retirement Specialist, LLC | 600 | $2.00K | 0.00% | +300+100.0% | Added |
| Parallel Advisors, LLC | 477 | $1.75K | 0.00% | 00.0% | Unchanged |
| NVWM, LLC | 416 | $1.52K | 0.00% | +416 | New |
| UBS Group AG | 403 | $1.48K | 0.00% | −4,111−91.1% | Reduced |
| Tortoise Investment Management, LLC | 400 | $1.46K | 0.00% | 00.0% | Unchanged |
| Emfo, LLC | 300 | $1.10K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 259 | $948 | 0.00% | +16+6.6% | Added |
| GWM Advisors LLC | 148 | $542 | 0.00% | 00.0% | Unchanged |
| Albion Financial Group | 132 | $484 | 0.00% | −191−59.1% | Reduced |
| Princeton Global Asset Management LLC | 100 | $366 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 100 | $366 | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 100 | $366 | 0.00% | +90+900.0% | Added |
| Fairman Group, LLC | 85 | $311 | 0.00% | +85 | New |
| Signaturefd, LLC | 68 | $249 | 0.00% | 00.0% | Unchanged |
| US Bancorp | 66 | $242 | 0.00% | 00.0% | Unchanged |
| Arrow Financial Corp | 66 | $242 | 0.00% | 00.0% | Unchanged |
| Hollencrest Capital Management | 66 | $242 | 0.00% | 00.0% | Unchanged |
| Westside Investment Management, Inc. | 66 | $242 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 66 | $242 | 0.00% | 00.0% | Unchanged |
| Tradewinds Capital Management, LLC | 53 | $194 | 0.00% | 00.0% | Unchanged |
| Signature Resources Capital Management, LLC | 53 | $194 | 0.00% | +53 | New |
| Louisbourg Investments Inc. | 52 | $190 | 0.00% | +52 | New |
| Plante Moran Financial Advisors, LLC | 36 | $132 | 0.00% | 00.0% | Unchanged |
| American Capital Advisory, LLC | 33 | $121 | 0.00% | +33 | New |
| Chesapeake Asset Management LLC | 33 | $120 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 30 | $110 | 0.00% | 00.0% | Unchanged |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 30 | $109 | 0.00% | +6+25.0% | Added |
| SRS Capital Advisors, Inc. | 28 | $103 | 0.00% | 00.0% | Unchanged |
| Robbins Farley LLC | 28 | $103 | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 28 | $102 | 0.00% | 00.0% | Unchanged |
| Pacifica Partners Inc. | 20 | $70 | 0.00% | 00.0% | Unchanged |
| Vima LLC | 19 | $70 | 0.00% | +19 | New |
| Northwestern Mutual Wealth Management Co | 16 | $59 | 0.00% | +16 | New |
| Castleview Partners, LLC | 16 | $59 | 0.00% | +16 | New |
| SJS Investment Consulting Inc. | 14 | $52 | 0.00% | 00.0% | Unchanged |
| JJJ Advisors Inc. | 10 | $37 | 0.00% | 00.0% | Unchanged |
| Focused Wealth Management, Inc | 10 | $37 | 0.00% | 00.0% | Unchanged |
| CNB Bank | 10 | $37 | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 9 | $33 | 0.00% | +9 | New |
| Strategic Investment Solutions, Inc. | 6 | $22 | 0.00% | −372−98.4% | Reduced |
| Belmont Capital, LLC | 6 | $22 | 0.00% | 00.0% | Unchanged |
| Glen Eagle Advisors, LLC | 6 | $22 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 6 | $22 | 0.00% | +6 | New |
| Hexagon Capital Partners LLC | 4 | $15 | 0.00% | +4 | New |
| AdvisorNet Financial, Inc | 3 | $11 | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 3 | $11 | 0.00% | +3 | New |
| Coppell Advisory Solutions LLC | 1 | $4 | 0.00% | +1 | New |