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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2021

Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
156
+148 vs. Q1 2021
Shares held
37.8M
+37.5M (+12,753.2%) vs. Q1 2021
Total value
$131.0M
+$130.1M (+13,959.7%) vs. Q1 2021
New holders
149
2 more added
Sold out
1
0 more reduced

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 156 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ2 2021: $131.0M
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2021.

Institutions holding DFTX in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock Inc.15,684,507$54.1M0.00%+15,684,507New
State Street Corp4,474,970$15.4M0.00%+4,474,970New
Geode Capital Management, LLC2,712,092$9.36M0.00%+2,712,092New
Vanguard Group Inc1,668,062$5.75M0.00%+1,668,062New
Susquehanna International Group, LLP1,238,242$4.27M0.00%+1,238,242New
Millennium Management LLC1,042,181$3.60M0.00%+1,042,181New
Bank of New York Mellon Corp751,353$2.59M0.00%+751,353New
Swiss National Bank716,500$2.50M0.00%+716,500New
Charles Schwab Investment Management Inc682,800$2.36M0.00%+682,800New
Jane Street Group, LLC622,364$2.16M0.01%+622,364New
California State Teachers Retirement System444,272$1.53M0.00%+444,272New
JPMorgan Chase & Co313,279$1.47M0.00%+313,279New
Alliancebernstein L.P.335,900$1.16M0.00%+335,900New
Citadel Advisors LLC320,263$1.10M0.00%+320,263New
Rhumbline Advisers292,324$1.01M0.00%+292,324New
Deutsche Bank AG288,924$997.0K0.00%+288,924New
New York State Common Retirement Fund275,900$952.0K0.00%+275,900New
Goldman Sachs Group Inc273,830$944.0K0.00%+273,830New
Credit Suisse AG238,034$822.0K0.00%+238,034New
Virtu Financial LLC232,906$804.0K0.08%+232,906New
Manufacturers Life Insurance Company, The175,798$758.0K0.00%+175,798New
Northern Trust Corp218,858$755.0K0.00%+218,858New
Simplex Trading, LLC204,271$704.0K0.03%+204,271New
American International Group, Inc.180,470$623.0K0.00%+180,470New
Morgan Stanley171,934$594.0K0.00%+171,934New
Shay Capital LLC170,450$588.0K0.14%+170,450New
Belvedere Trading LLC183,144$582.0K0.24%+183,144New
tru Independence LLC167,293$577.0K0.17%00.0%Unchanged
UBS Asset Management Americas Inc163,000$567.3K0.00%+163,000New
Bank of Montreal148,493$539.0K0.00%+148,493New
Invesco Ltd.152,937$528.0K0.00%+152,937New
BIT Capital GmbH140,000$483.0K0.03%+140,000New
D. E. Shaw & Co., Inc.132,803$458.0K0.00%+132,803New
Voya Investment Management LLC126,479$436.0K0.00%+126,479New
MetLife Investment Management125,919$434.4K0.00%+125,919New
Penserra Capital Management LLC123,409$425.0K0.01%+123,409New
Commonwealth Equity Services, LLC120,192$418.0K0.00%+120,192New
Group One Trading, L.P.112,089$387.0K0.01%+112,089New
Royal Bank of Canada109,269$377.0K0.00%+109,269New
Metropolitan Life Insurance Co96,406$332.6K0.00%+96,406New
Scotia Capital Inc.83,138$288.0K0.00%+83,138New
ProShare Advisors LLC83,556$288.0K0.00%+83,556New
Wolverine Trading, LLC79,364$286.0K0.01%+79,364New
AdvisorShares Investments LLC80,000$276.0K0.04%+80,000New
STRS Ohio74,700$257.0K0.00%+74,700New
Gofen & Glossberg LLC72,500$250.0K0.01%00.0%Unchanged
HAP Trading, LLC68,055$235.0K0.01%+68,055New
Huntington National Bank60,000$207.0K0.00%+60,000New
HighTower Advisors, LLC57,482$198.0K0.00%+57,482New
Legal & General Group Plc51,623$182.0K0.00%+51,623New
Principal Financial Group Inc51,494$178.0K0.00%+51,494New
Bank of America Corp49,809$172.0K0.00%+49,809New
Parametric Portfolio Associates LLC48,450$167.0K0.00%+48,450New
Toronto Dominion Bank46,223$160.0K0.00%+46,223New
Stokes Family Office, LLC46,095$160.0K0.02%+46,095New
Stifel Financial Corp44,740$154.0K0.00%+44,740New
LPL Financial LLC44,170$152.0K0.00%+44,170New
Two Sigma Advisers, LP43,500$150.0K0.00%+43,500New
FNY Investment Advisers, LLC41,300$142.0K0.06%+21,300+106.5%Added
Private Advisor Group, LLC41,183$141.0K0.00%+41,183New
Jaffetilchin Investment Partners, LLC37,580$131.0K0.01%+37,580New
Advisor Group Holdings, Inc.36,292$124.0K0.00%+36,292New
Stratos Wealth Partners, LTD.32,476$112.0K0.00%+32,476New
Intersect Capital LLC32,500$112.0K0.02%+32,500New
Arete Wealth Advisors, LLC32,498$111.0K0.02%+32,498New
Shell Asset Management Co30,022$104.0K0.00%+30,022New
MYDA Advisors LLC30,000$104.0K0.03%+30,000New
IHT Wealth Management, LLC30,000$104.0K0.01%+30,000New
American Portfolios Advisors30,000$103.5K0.00%+30,000New
Price T Rowe Associates Inc27,801$96.0K0.00%+27,801New
Ameritas Investment Partners, Inc.25,253$87.0K0.00%+25,253New
Conservest Capital Advisors, Inc.23,444$81.0K0.01%+23,444New
Accurate Wealth Management, LLC22,550$78.0K0.07%+22,550New
Creative Planning22,136$76.0K0.00%+22,136New
Prudential Financial Inc21,640$75.0K0.00%+21,640New
K.J. Harrison & Partners Inc21,500$75.0K0.01%+21,500New
CWM, LLC20,900$72.0K0.00%00.0%Unchanged
Sandy Spring Bank19,424$67.0K0.00%+19,424New
Sara-Bay Financial19,204$66.0K0.03%+19,204New
SG Americas Securities, LLC17,546$61.0K0.00%+17,546New
Xponance, Inc.17,630$61.0K0.00%+17,630New
Texas Yale Capital Corp.17,300$60.0K0.00%+17,300New
Federation des caisses Desjardins du Quebec17,259$59.6K0.00%+17,259New
Engineers Gate Manager LP17,144$59.0K0.00%+17,144New
Point72 Hong Kong Ltd16,821$58.0K0.00%+16,821New
Gerber Kawasaki Wealth & Investment Management17,012$58.0K0.01%+17,012New
Blair William & Co15,926$55.0K0.00%+15,926New
Pictet Asset Management Ltd15,700$54.0K0.00%+15,700New
Citigroup Inc15,330$53.0K0.00%+15,330New
Veritable, L.P.15,100$52.0K0.00%+15,100New
Koshinski Asset Management, Inc.15,160$52.0K0.01%+15,160New
Eudaimonia Partners, LLC15,000$52.0K0.01%+15,000New
Platform Technology Partners15,000$52.0K0.02%+15,000New
Invst, LLC16,058$51.0K0.01%+16,058New
Newport Wealth Strategies, Inc.13,200$46.0K0.03%+13,200New
Pacitti Group Inc.12,875$44.0K0.03%+12,875New
IFP Advisors, Inc12,157$42.0K0.00%+10,657+710.5%Added
EP Wealth Advisors, LLC12,292$42.0K0.00%+12,292New
Csenge Advisory Group12,112$42.0K0.00%+12,112New
Truist Financial Corp11,468$40.0K0.00%+11,468New