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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2024

Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
135
+33 vs. Q4 2023
Shares held
34.8M
+29.9M (+612.9%) vs. Q4 2023
Total value
$327.2M
+$309.4M (+1,731.0%) vs. Q4 2023
New holders
46
31 more added
Sold out
13
17 more reduced

2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 135 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ1 2024: $327.2M
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2023.

Institutions holding DFTX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
TSFG, LLC24$00.00%00.0%Unchanged
Huntington National Bank1$10.00%00.0%Unchanged
Sofos Investments, Inc.2$190.00%+2New
Rothschild Investment LLC3$280.00%00.0%Unchanged
Macquarie Group Ltd3,779$360.00%+3,779New
Hexagon Capital Partners LLC4$380.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC6$560.00%00.0%Unchanged
Belmont Capital, LLC6$560.00%00.0%Unchanged
Glen Eagle Advisors, LLC6$560.00%00.0%Unchanged
Vima LLC29$920.00%+10+52.6%Added
JJJ Advisors Inc.10$940.00%00.0%Unchanged
CNB Bank10$940.00%00.0%Unchanged
American Capital Advisory, LLC33$1050.00%00.0%Unchanged
SJS Investment Consulting Inc.12$1130.00%−2−14.3%Reduced
CoreCap Advisors, LLC15$1410.00%+15New
Castleview Partners, LLC16$1500.00%00.0%Unchanged
Parallel Advisors, LLC19$1790.00%−458−96.0%Reduced
Continuum Advisory, LLC20$1820.00%+20New
Signature Resources Capital Management, LLC53$1940.00%00.0%Unchanged
Pacifica Partners Inc.20$2080.00%00.0%Unchanged
Nelson, Van Denburg & Campbell Wealth Management Group, LLC24$2250.00%−6−20.0%Reduced
HighMark Wealth Management LLC28$2630.00%00.0%Unchanged
SRS Capital Advisors, Inc.28$2640.00%00.0%Unchanged
Robbins Farley LLC28$2640.00%00.0%Unchanged
IFP Advisors, Inc30$2820.00%00.0%Unchanged
Chesapeake Asset Management LLC33$3100.00%00.0%Unchanged
Plante Moran Financial Advisors, LLC36$3380.00%00.0%Unchanged
Louisbourg Investments Inc.52$4920.00%00.0%Unchanged
Tradewinds Capital Management, LLC53$4990.00%00.0%Unchanged
Toronto Dominion Bank55$5170.00%−2,102−97.5%Reduced
Arrow Financial Corp66$6200.00%00.0%Unchanged
Hollencrest Capital Management66$6200.00%00.0%Unchanged
Westside Investment Management, Inc.66$6200.00%00.0%Unchanged
Allworth Financial LP66$6210.00%00.0%Unchanged
Signaturefd, LLC68$6390.00%00.0%Unchanged
Fairman Group, LLC85$7990.00%00.0%Unchanged
Farther Finance Advisors, LLC100$9520.00%00.0%Unchanged
Albion Financial Group132$1.24K0.00%00.0%Unchanged
GWM Advisors LLC148$1.39K0.00%00.0%Unchanged
Cutler Group LP300$2.00K0.00%+171+132.6%Added
Federated Hermes, Inc.247$2.32K0.00%+247New
Harbour Investments, Inc.279$2.62K0.00%+179+179.0%Added
Emfo, LLC300$2.82K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co368$3.46K0.00%+352+2,200.0%Added
Tortoise Investment Management, LLC400$3.76K0.00%00.0%Unchanged
NVWM, LLC416$3.91K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC434$4.13K0.00%+434New
NBC Securities, Inc.600$5.00K0.00%+600New
Symmetry Peak Management LLC800$7.52K0.15%+800New
CWM, LLC1,538$14.0K0.00%+270+21.3%Added
National Bank of Canada1,742$16.1K0.00%+75+4.5%Added
Crewe Advisors LLC1,999$18.8K0.00%00.0%Unchanged
North Star Investment Management Corp.2,150$20.2K0.00%+2,150New
Wells Fargo & Company2,583$24.3K0.00%+2,324+897.3%Added
JPMorgan Chase & Co3,516$33.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.3,741$35.2K0.00%+464+14.2%Added
Deutsche Bank AG5,613$52.8K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)5,763$54.2K0.00%−57−1.0%Reduced
TD Waterhouse Canada Inc.4,537$59.9K0.00%+3,880+590.6%Added
Barclays PLC9,147$86.0K0.00%00.0%Unchanged
Thrivent Financial for Lutherans10,027$94.0K0.00%+10,027New
Brevan Howard Capital Management LP10,649$100.1K0.01%+10,649New
Blair William & Co11,341$106.6K0.00%+11,341New
Polymer Capital Management (HK) LTD11,926$112.1K0.03%+11,926New
Raymond James Financial Services Advisors, Inc.13,762$129.4K0.00%+13,762New
Mercer Global Advisors Inc14,928$140.0K0.00%+14,928New
PEAK6 Investments LLC15,454$145.3K0.01%+15,454New
Federation des caisses Desjardins du Quebec14,121$149.1K0.00%−66−0.5%Reduced
Chiron Investment Management, LLC15,932$149.8K0.06%+15,932New
LMR Partners LLP16,374$153.9K0.00%+16,374New
Sequoia Financial Advisors, LLC17,912$168.4K0.00%+17,912New
Mitchell McLeod Pugh & Williams Inc20,000$188.0K0.05%00.0%Unchanged
Two Sigma Advisers, LP21,917$206.0K0.00%+21,917New
Y-Intercept (Hong Kong) Ltd23,316$219.2K0.02%+6,463+38.3%Added
Bailard, Inc.24,100$226.5K0.01%+6,800+39.3%Added
Rathbone Brothers plc24,200$227.5K0.00%−800−3.2%Reduced
UBS Group AG24,384$229.2K0.00%+23,981+5,950.6%Added
FMR LLC24,577$231.0K0.00%+770+3.2%Added
Commonwealth Equity Services, LLC24,852$234.0K0.00%+8,322+50.3%Added
GTS Securities LLC24,921$234.3K0.01%+24,921New
Virtu Financial LLC25,440$239.0K0.02%+25,440New
Bank of America Corp26,182$246.1K0.00%−5,860−18.3%Reduced
Cubist Systematic Strategies, LLC28,618$269.0K0.00%+28,618New
Caxton Corp29,065$273.2K1.56%+29,065New
Laurion Capital Management LP30,426$286.0K0.01%+30,426New
Group One Trading, L.P.36,358$341.8K0.01%−74,070−67.1%Reduced
Royal Bank of Canada40,619$381.0K0.00%+35,234+654.3%Added
Wolverine Trading, LLC41,296$388.2K0.00%+31,059+303.4%Added
Bank of New York Mellon Corp42,992$404.1K0.00%−19,254−30.9%Reduced
LPL Financial LLC43,727$411.0K0.00%+8,497+24.1%Added
Kestra Private Wealth Services, LLC51,339$482.6K0.01%00.0%Unchanged
Scotia Capital Inc.53,951$505.9K0.00%−67,805−55.7%Reduced
Simplex Trading, LLC54,848$515.0K0.02%+45,871+511.0%Added
Wellington Management Group LLP55,065$517.6K0.00%+55,065New
Citadel Advisors LLC57,320$538.8K0.00%+56,235+5,182.9%Added
Squarepoint Ops LLC57,650$541.9K0.00%+57,650New
Northern Trust Corp65,549$616.2K0.00%+3,486+5.6%Added
Boothbay Fund Management, LLC84,624$795.5K0.02%−62,036−42.3%Reduced
Data Collective IV GP, LLC100,350$943.3K0.82%00.0%Unchanged
AdvisorShares Investments LLC109,507$1.03M0.17%−3,267−2.9%Reduced