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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2022

Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
159
−16 vs. Q4 2021
Shares held
48.4M
−3.55M (−6.8%) vs. Q4 2021
Total value
$53.6M
−$18.4M (−25.6%) vs. Q4 2021
New holders
32
34 more added
Sold out
48
41 more reduced

1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 159 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ1 2022: $53.6M
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2021.

Institutions holding DFTX in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
SJS Investment Consulting Inc.30$00.00%−4,000−99.3%Reduced
Montag A & Associates Inc57$00.00%00.0%Unchanged
Signaturefd, LLC30$00.00%00.0%Unchanged
Focused Wealth Management, Inc160$00.00%00.0%Unchanged
JJJ Advisors Inc.150$00.00%00.0%Unchanged
Gemmer Asset Management LLC20$00.00%00.0%Unchanged
Sargent Bickham Lagudis LLC160$00.00%00.0%Unchanged
Foresight Capital Management Advisors, Inc.288$00.00%00.0%Unchanged
Sterling Investment Advisors, Ltd.30$00.00%00.0%Unchanged
PrairieView Partners, LLC67$00.00%00.0%Unchanged
Larson Financial Group LLC210$00.00%00.0%Unchanged
Professional Financial Advisors, LLC84$00.00%00.0%Unchanged
Pacifica Partners Inc.300$00.00%00.0%Unchanged
Robbins Farley LLC350$00.00%+130+59.1%Added
Charter Oak Capital Management, LLC405$00.00%+405New
Heritage Wealth Management, LLC300$00.00%+300New
Laffer Tengler Investments100$1110.00%00.0%Unchanged
Glen Eagle Advisors, LLC433$4810.00%+433New
Burleson & Company, LLC1,301$1.00K0.00%00.0%Unchanged
Arrow Financial Corp1,000$1.00K0.00%00.0%Unchanged
American Research & Management Co.1,000$1.00K0.00%00.0%Unchanged
Pflug Koory, LLC520$1.00K0.00%00.0%Unchanged
Banque Cantonale Vaudoise763$1.00K0.00%00.0%Unchanged
1832 Asset Management L.P.700$1.00K0.00%+700New
Allworth Financial LP1,000$1.00K0.00%+1,000New
Geneos Wealth Management Inc.1,000$1.00K0.00%+1,000New
RPg Family Wealth Advisory, LLC1,000$1.11K0.00%+1,000New
US Bancorp2,000$2.00K0.00%00.0%Unchanged
Front Row Advisors LLC2,000$2.00K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.2,239$2.00K0.00%+5+0.2%Added
Baldrige Asset Management LLC2,000$2.00K0.00%00.0%Unchanged
TFC Financial Management2,000$2.00K0.00%00.0%Unchanged
HighMark Wealth Management LLC2,003$2.00K0.00%+2,003New
Tradewinds Capital Management, LLC2,300$3.00K0.00%+1,500+187.5%Added
Captrust Financial Advisors3,778$4.00K0.00%−1,000−20.9%Reduced
Kistler-Tiffany Companies, LLC3,275$4.00K0.00%00.0%Unchanged
Albion Financial Group4,870$5.00K0.00%00.0%Unchanged
Clearstead Advisors, LLC4,405$5.00K0.00%00.0%Unchanged
Tortoise Investment Management, LLC6,000$7.00K0.00%00.0%Unchanged
Private Capital Group, LLC6,097$7.00K0.00%00.0%Unchanged
VisionPoint Advisory Group, LLC10,000$7.00K0.00%+10,000New
Advisor Group Holdings, Inc.7,631$9.00K0.00%−5,905−43.6%Reduced
Tower Research Capital LLC (TRC)9,121$10.0K0.00%−983−9.7%Reduced
Chase Investment Counsel Corp10,375$11.0K0.00%00.0%Unchanged
First National Trust Co10,000$11.0K0.00%00.0%Unchanged
Boothbay Fund Management, LLC11,040$12.0K0.00%00.0%Unchanged
NorthRock Partners, LLC10,750$12.0K0.00%−31−0.3%Reduced
Almanack Investment Partners, LLC.10,471$12.0K0.00%+10,471New
TD Waterhouse Canada Inc.10,054$12.4K0.00%−3,346−25.0%Reduced
Conservest Capital Advisors, Inc.11,944$13.0K0.00%−11,751−49.6%Reduced
HRT Financial LP12,110$13.0K0.00%−5,633−31.7%Reduced
United Capital Financial Advisers, LLC11,699$13.0K0.00%−1,880−13.8%Reduced
Apollon Wealth Management, LLC11,427$13.0K0.00%+11,427New
EP Wealth Advisors, LLC12,372$14.0K0.00%00.0%Unchanged
FMR LLC13,024$14.0K0.00%+13,024New
Oppenheimer & Co Inc12,825$14.0K0.00%+12,825New
Ausdal Financial Partners, Inc.12,970$14.0K0.00%+12,970New
Pacitti Group Inc.12,600$14.0K0.01%+12,600New
Endowment Wealth Management, Inc.12,413$14.0K0.01%+12,413New
MAI Capital Management13,201$15.0K0.00%00.0%Unchanged
Exchange Traded Concepts, LLC13,553$15.0K0.00%+13,553New
Sawtooth Solutions, LLC13,315$15.0K0.00%+13,315New
Xponance, Inc.15,230$17.0K0.00%−1,256−7.6%Reduced
Veritable, L.P.15,100$17.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co15,727$17.5K0.00%−61,625−79.7%Reduced
Citigroup Inc15,337$18.0K0.00%−78,979−83.7%Reduced
Beacon Pointe Advisors, LLC16,567$18.0K0.00%+16,567New
Strategic Blueprint, LLC16,000$18.0K0.00%+16,000New
Federation des caisses Desjardins du Quebec16,559$18.3K0.00%00.0%Unchanged
Raymond James & Associates17,032$19.0K0.00%+17,032New
CIBC World Markets Inc.18,206$20.0K0.00%+2,660+17.1%Added
Fulton Breakefield Broenniman LLC17,750$20.0K0.00%+5,000+39.2%Added
JSF Financial, LLC18,215$20.0K0.01%+18,215New
Two Sigma Securities, LLC18,769$21.0K0.00%−17,578−48.4%Reduced
Prudential Financial Inc20,240$22.0K0.00%00.0%Unchanged
Regions Financial Corp20,000$22.0K0.00%00.0%Unchanged
Mackenzie Financial Corp19,191$22.0K0.00%00.0%Unchanged
Close Asset Management Ltd16,000$22.0K0.00%00.0%Unchanged
Eudaimonia Partners, LLC20,000$22.0K0.00%+20,000New
Fisher Asset Management, LLC20,500$23.0K0.00%+375+1.9%Added
IFP Advisors, Inc29,709$23.0K0.00%+18,652+168.7%Added
Glenmede Trust Co NA21,585$23.0K0.00%+21,585New
Freestone Capital Holdings, LLC20,685$23.0K0.00%+20,685New
UBS Group AG21,331$24.0K0.00%−85,500−80.0%Reduced
K.J. Harrison & Partners Inc21,500$24.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC21,940$24.0K0.00%+21,940New
Parametric Portfolio Associates LLC25,362$28.0K0.00%−188,790−88.2%Reduced
Ameritas Investment Partners, Inc.25,253$28.0K0.00%00.0%Unchanged
Virtu Financial LLC26,036$29.0K0.00%+26,036New
Pictet Asset Management SA27,463$30.0K0.00%00.0%Unchanged
Huntington National Bank30,001$33.0K0.00%00.0%Unchanged
Price T Rowe Associates Inc29,492$33.0K0.00%+6,506+28.3%Added
American Portfolios Advisors30,000$33.3K0.00%00.0%Unchanged
Alpine Global Management, LLC31,750$35.0K0.01%−27,940−46.8%Reduced
National Bank of Canada33,510$37.0K0.00%−143,543−81.1%Reduced
Stratos Wealth Partners, LTD.33,604$37.0K0.00%00.0%Unchanged
Cutler Group LP33,389$37.0K0.00%+3,500+11.7%Added
Accurate Wealth Management, LLC34,340$38.0K0.02%+34,340New
Shell Asset Management Co37,982$43.0K0.00%00.0%Unchanged
HSBC Holdings PLC43,081$48.0K0.00%+4,852+12.7%Added