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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

Q2 2026 vs. Q1 2026

How the institutions holding Definium Therapeutics, Inc. changed between Q1 2026 and Q2 2026.

All holders in Q2 2026All holders in Q1 2026

13F holders of DFTX: Q1 2026 compared with Q2 2026
MeasureQ1 2026Of which not filed for Q2 2026Q2 2026Change
Holders2485362+119
Shares78.1M3.56M114.8M+40.3M (+54.1%)
Value$1.47B$67.3M$5.35B+$3.94B (+280.1%)

5 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (148)

Institutions that held Definium Therapeutics, Inc. at the end of Q2 2026 but not at the end of Q1 2026.

Showing the largest 100 of 148 by value.

Institutions new to DFTX in Q2 2026
InstitutionSharesValue% of portfolio
Jupiter Topco LLC5,615,645$264.0M0.11%
Capital World Investors5,367,723$252.5M0.03%
Capital International Investors2,963,410$139.4M0.03%
Ra Capital Management, L.P.1,500,000$70.6M0.61%
Polar Capital Holdings Plc777,253$36.6M0.10%
Bamco Inc520,108$24.5M0.04%
Franklin Resources Inc486,219$22.9M0.00%
Great Point Partners LLC425,000$20.0M4.71%
Cormorant Asset Management, LP400,000$18.8M0.96%
Silverarc Capital Management, LLC400,000$18.8M2.09%
Assetmark, Inc396,542$18.7M0.03%
Duquesne Family Office LLCSuperinvestorDuquesne Family Office356,600$16.8M0.39%
Trexquant Investment LP233,199$11.0M0.07%
TD Asset Management Inc209,460$9.85M0.01%
SEB Asset Management AB208,254$9.80M0.04%
Emerald Advisers, LLC178,751$8.41M0.20%
Standard Life Aberdeen plc175,000$8.23M0.01%
LMR Partners LLP150,200$7.07M0.05%
Rock Springs Capital Management LP143,187$6.74M0.33%
SummitTX Capital, L.P.142,489$6.70M0.18%
California State Teachers Retirement System128,346$6.04M0.01%
Atika Capital Management LLC122,000$5.74M0.57%
Emerald Mutual Fund Advisers Trust121,249$5.70M0.20%
EAM Investors, LLC120,928$5.69M0.51%
HSBC Holdings PLC117,482$5.53M0.00%
Alps Advisors Inc110,388$5.19M0.02%
Keystone Investors Pte Ltd95,100$4.47M0.24%
Pier Capital, LLC88,598$4.17M0.55%
Squadron Capital Management LLC85,000$4.00M1.37%
XTX Topco Ltd84,393$3.97M0.05%
Shay Capital LLC80,000$3.76M0.42%
Logos Global Management LP80,000$3.76M0.16%
Sectoral Asset Management Inc78,310$3.68M2.57%
Algert Global LLC63,700$3.00M0.04%
Peak Financial Advisors LLC56,915$2.68M1.11%
Y-Intercept (Hong Kong) Ltd54,466$2.56M0.05%
Cerity Partners LLC53,883$2.53M0.00%
Moody Aldrich Partners LLC51,025$2.40M0.43%
Atom Investors LP49,436$2.33M0.21%
Polymer Capital Management (HK) LTD44,100$2.07M0.21%
Aquatic Capital Management LLC43,124$2.03M0.07%
Ghisallo Capital Management LLC41,500$1.95M0.04%
Vestmark Advisory Solutions, Inc.30,729$1.45M0.01%
Stableford Capital II LLC27,141$1.28M0.44%
Janney Montgomery Scott LLC26,664$1.25M0.00%
ACT Capital Management, LLC25,000$1.18M0.77%
Teachers Retirement System of the State of Kentucky24,500$1.15M0.01%
CI Private Wealth, LLC24,391$1.15M0.00%
IFG Advisory, LLC22,043$1.04M0.04%
TFB Advisors LLC21,523$1.01M0.45%
Birchview Capital, LP20,000$940.8K0.44%
Fore Capital, LLC20,000$940.8K1.25%
Envestnet Asset Management Inc16,626$782.1K0.00%
Cary Street Partners Financial LLC15,582$733.0K0.02%
Prudential Financial Inc15,500$729.1K0.00%
Diadema Partners LP15,451$726.8K0.26%
Allianz Asset Management GmbH13,800$649.2K0.00%
FORA Capital, LLC13,378$628.9K0.04%
Private Advisor Group, LLC13,336$627.3K0.00%
Dymon Asia Capital (Singapore) Pte. Ltd.13,289$625.1K0.10%
Xponance, Inc.12,716$598.2K0.00%
State of Wyoming12,448$585.6K0.06%
Axq Capital, LP12,444$585.4K0.06%
Captrust Financial Advisors12,148$571.4K0.00%
Glenmede Trust Co NA11,548$543.2K0.00%
Mount Yale Investment Advisors, LLC11,382$535.4K0.01%
Entropy Technologies, LP10,688$502.8K0.02%
Mercer Global Advisors Inc10,278$483.5K0.00%
Capital Fund Management S.A.10,128$476.4K0.00%
Principal Financial Group Inc9,952$468.1K0.00%
First Trust Advisors LP9,527$448.1K0.00%
Quantbot Technologies LP9,230$434.2K0.02%
Diversify Advisory Services, LLC10,025$427.6K0.01%
Mangrove Partners9,079$427.1K0.03%
Fearless Solutions, LLC dba Best Invest8,804$414.1K0.22%
Rafferty Asset Management, LLC8,548$402.1K0.00%
Fieldview Capital Management, LLC8,493$399.5K0.11%
Bellevue Group AG8,391$394.7K0.01%
Connor, Clark & Lunn Investment Management Ltd.8,295$390.2K0.00%
Flagship Harbor Advisors, LLC7,966$374.7K0.01%
Wealth Enhancement Advisory Services, LLC7,952$374.3K0.00%
CIBC Bancorp USA Inc.7,711$362.7K0.00%
Omers Administration Corp7,600$357.5K0.00%
Abel Hall, LLC7,551$355.2K0.06%
Action Point Financial Planning, LLC7,483$352.0K0.04%
EntryPoint Capital, LLC7,331$344.9K0.08%
Centiva Capital, LP7,242$340.7K0.01%
Change Path, LLC7,202$338.8K0.01%
Jump Financial, LLC7,064$332.3K0.00%
Chiron Capital Management, LLC7,000$329.3K0.30%
Creative Planning6,906$324.9K0.00%
McAdam, LLC6,879$323.6K0.01%
Two Sigma Securities, LLC6,704$315.4K0.03%
Sig Brokerage, LP6,563$308.7K0.05%
AMG National Trust Bank6,369$299.6K0.01%
Insigneo Advisory Services, LLC6,341$298.3K0.01%
Waldron Private Wealth LLC6,321$297.3K0.01%
Bailard, Inc.6,277$295.3K0.01%
Fiduciary Alliance LLC6,000$282.2K0.02%
Retirement Financial Solutions, LLC6,000$282.2K0.07%

Sold out (29)

Institutions that held Definium Therapeutics, Inc. at the end of Q1 2026 and filed for Q2 2026 without it.

Institutions that sold out of DFTX in Q2 2026
InstitutionShares, Q1 2026Value, Q1 2026
Trails Edge Capital Partners, LP1,738,110$32.9M
Patient Square Capital LP331,000$6.26M
Jane Street Group, LLC260,241$4.92M
Soviero Asset Management, LP140,000$2.65M
Squarepoint Ops LLC125,522$2.37M
Rosalind Advisors, Inc.125,000$2.36M
ExodusPoint Capital Management, LP104,915$1.98M
HRT Financial LP89,141$1.68M
Ikarian Capital, LLC58,803$1.11M
Twinbeech Capital LP42,100$795.7K
Caxton Associates LLP37,255$704.1K
Campbell & CO Investment Adviser LLC24,755$467.9K
Virtu Financial LLC14,460$273.0K
Boothbay Fund Management, LLC14,096$266.4K
Fox Run Management, L.L.C.14,557$254.7K
Magnetar Financial LLC13,178$249.1K
Summit Trail Advisors, LLC13,000$245.7K
RPS Advisory Solutions LLC11,355$214.6K
Dynamic Technology Lab Private Ltd10,880$205.6K
Verition Fund Management LLC10,384$196.3K
Sound Income Strategies, LLC3,690$76.0K
Advisory Services Network, LLC2,659$50.3K
Opal Wealth Advisors, LLC1,101$20.8K
Private Wealth Management Group, LLC450$8.51K
Meeder Asset Management Inc353$6.67K
Federated Hermes, Inc.207$3.91K
Louisbourg Investments Inc.52$983
RMG Wealth Management LLC30$642
CoreCap Advisors, LLC5$95

Not filed for Q2 2026 yet (5)

Institutions that held Definium Therapeutics, Inc. at the end of Q1 2026 and haven't filed a 13F for Q2 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding DFTX in Q1 2026 that haven't filed for Q2 2026
InstitutionShares, Q1 2026Value, Q1 2026
Janus Henderson Group PLC3,556,041$67.2M
CWM, LLC5,600$105.8K
Sunbelt Securities, Inc.44$832
Anfield Capital Management, LLC36$680
Sofos Investments, Inc.35$662